- Must visit
Musée des Confluences
A striking science and anthropology museum at the meeting of the Rhône and Saône, known for bold architecture and major permanent exhibitions.
Cheapest price
$15
Average price
$41
Fastest journey
6 h 10 m
Average duration
6 h 19 m
Buses per day
25
Distance
339 km
The best way to find a cheap bus ticket from Milan to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Lyon will cost around $41 if you buy it on the day, but the cheapest tickets can be found for only $15.
Of the 25 buses that leave Milan for Lyon on Fri, May 22, 20 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 22 the direct buses cover the 339 km distance in an average of 6 h 19 m but if you time it right, some buses will get you there in just 6 h 10 m .
On Fri, May 22 the slowest buses will take 6 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3090
3492
4768
1726
4750
FlixBus
FlixBus
FlixBus
FlixBus
3090Omio recommends booking the bus as it is the most popular option from Milan to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a flight which can get you there in 2h 34m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $15, and a flight costs an average of $120.
Distance: 210 miles (339 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$32 Average price Cheapest | $129 Average price | $295 Average price | $245 Average price (fuel + tolls) |
7h 14m Average total duration 6h 44m Onboard + 30m Additional time* | 6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 5h 34m Average total duration Fastest 2h 34m Onboard + 3h 0m Additional time* | 5h 17m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Lyon:
A bus is $97 (€78) less than a train for this route with tickets for a train from Milan to Lyon costing on average $129 (€104).
A bus is $263 (€213) less than a flight for this route with tickets for a flight from Milan to Lyon costing on average $295 (€239).
Other travel options to Lyon take longer:
Train takes on average 6h 18m.
Bus takes on average 6h 44m.
Tickets start at around $32 (€26) compared to roughly $245 (€198) in fuel and tolls — a saving of about $213 (€172). The journey takes 6h 44m versus 5h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, FlixBus, Itabus, Union Ivkoni International, BlaBlaCar, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:30AM | Arrival Time 08:45AM | Duration 8h15 | Departure days Mon, Fri, Sat, Sun | Cheapest price $59 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 12:00PM | Duration 6h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $30 |
Operator | Departure Time 06:00AM | Arrival Time 02:15PM | Duration 8h15 | Departure days Wed, Fri | Cheapest price $32 |
Operator Itabus | Departure Time 06:20AM | Arrival Time 12:55PM | Duration 6h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $19 |
Operator | Departure Time 06:45AM | Arrival Time 03:00PM | Duration 8h15 | Departure days Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 02:10PM | Duration 6h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 03:05PM | Duration 6h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 01:50PM | Duration 4h50 | Departure days Sat | Cheapest price $37 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 04:25PM | Duration 7h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $22 |
Operator BlaBlaCar Bus | Departure Time 10:20AM | Arrival Time 05:05PM | Duration 6h45 | Departure days Mon, Fri, Sat, Sun | Cheapest price $31 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 01:25AM | Duration 15h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $82 |
Operator BlaBlaCar Bus | Departure Time 10:35AM | Arrival Time 06:50PM | Duration 8h15 | Departure days Mon, Fri, Sat, Sun | Cheapest price $31 |
Operator BlaBlaCar Bus | Departure Time 11:35AM | Arrival Time 07:35PM | Duration 8h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 06:10PM | Duration 5h40 | Departure days Fri | Cheapest price $43 |
Operator Itabus | Departure Time 02:55PM | Arrival Time 09:30PM | Duration 6h35 | Departure days Everyday | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 07:50PM | Duration 4h50 | Departure days Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 09:10PM | Duration 6h10 | Departure days Everyday | Cheapest price $54 |
Operator BlaBlaCar Bus | Departure Time 04:00PM | Arrival Time 10:55PM | Duration 6h55 | Departure days Everyday | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 08:20PM | Duration 4h20 | Departure days Sun | Cheapest price $40 |
Operator BlaBlaCar Bus | Departure Time 05:00PM | Arrival Time 11:50PM | Duration 6h50 | Departure days Wed, Thu, Sat, Sun | Cheapest price $17 |
Operator Itabus | Departure Time 05:50PM | Arrival Time 12:25AM | Duration 6h35 | Departure days Everyday | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 10:30PM | Duration 4h30 | Departure days Thu | Cheapest price $51 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:35AM | Duration 6h35 | Departure days Everyday | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 06:40PM | Arrival Time 11:40PM | Duration 5h00 | Departure days Fri | Cheapest price $44 |
Operator BlaBlaCar Bus | Departure Time 06:50PM | Arrival Time 01:20AM | Duration 6h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 07:10PM | Arrival Time 12:30AM | Duration 5h20 | Departure days Sat | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 07:20PM | Arrival Time 12:30AM | Duration 5h10 | Departure days Fri | Cheapest price $46 |
Operator BlaBlaCar Bus | Departure Time 08:00PM | Arrival Time 02:20AM | Duration 6h20 | Departure days Wed, Thu, Sat, Sun | Cheapest price $22 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:45AM | Duration 11h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 03:55AM | Duration 6h20 | Departure days Everyday | Cheapest price $32 |
Operator Itabus | Departure Time 10:25PM | Arrival Time 04:55AM | Duration 6h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 04:50AM | Duration 6h20 | Departure days Everyday | Cheapest price $32 |
Operator BlaBlaCar Bus | Departure Time 11:35PM | Arrival Time 06:45AM | Duration 7h10 | Departure days Everyday | Cheapest price $17 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 06:30AM | Duration 6h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $30 |
The table below shows live departures for Milan to Lyon buses for today, Thursday, May 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
3492 | 2:55 PM Milano, Autostazione Lampugnano | 6h35 | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 6h10 | 9:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4750 | 4:00 PM Milano, Autostazione Lampugnano | 6h55 | 10:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
51065 | 5:00 PM Milano, Autostazione Lampugnano | 6h50 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
3092 | 5:50 PM Milano, Autostazione Lampugnano | 6h35 | 12:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 6:00 PM Milano, Autostazione Lampugnano | 6h35 | 12:35 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
94742 | 6:50 PM Milano, Autostazione Lampugnano | 6h30 | 1:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
94782 | 8:00 PM Milano, Autostazione Lampugnano | 6h20 | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 9:00 PM Milano, Milan Linate Airport | 11h45 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 9:35 PM Milano, Autostazione Lampugnano | 6h20 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
3090 | 10:25 PM Milano, Autostazione Lampugnano | 6h30 | 4:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 10:30 PM Milano, Autostazione Lampugnano | 6h20 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4768 | 11:35 PM Milano, Autostazione Lampugnano | 7h10 | 6:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:45 PM Milano, Autostazione Lampugnano | 6h45 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Friday, May 22 | |||||
FlixBus · FlixBus | 12:30 AM Milano, Autostazione Lampugnano | 8h15 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 5:45 AM Milano, Autostazione Lampugnano | 6h15 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
![]() | 6:00 AM Milan, Lampugnano (M1) | 8h15 | 2:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
3898 | 6:20 AM Milano, Autostazione Lampugnano | 6h35 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:30 AM Milano, Autostazione Lampugnano | 6h40 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 8:30 AM Milano, Autostazione Lampugnano | 6h35 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 9:15 AM Milano, Autostazione Lampugnano | 7h10 | 4:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
94766 | 10:20 AM Milano, Autostazione Lampugnano | 6h45 | 5:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 12h20 | 10:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1716 | 10:35 AM Milano, Autostazione Lampugnano | 8h15 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
1716 · 80014 | 10:35 AM Milano, Autostazione Lampugnano | 8h20 | 6:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1726 | 11:35 AM Milano, Autostazione Lampugnano | 8h00 | 7:35 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Lyon run on average 22 times per day, taking around 6h 44m. Cheap bus tickets for this journey start at $15 (€12) if you book in advance.
There are 17 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 210 miles (339 km) distance in 6h 20m.
Distance 210 miles (339 km) |
Average bus duration 6h 44m |
Cheapest ticket price $15 (€12) |
Buses per day 22 |
Direct buses 17 |
Fastest bus 6h 20m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A striking science and anthropology museum at the meeting of the Rhône and Saône, known for bold architecture and major permanent exhibitions.
One of France’s leading fine arts museums, housed in a former abbey with strong collections from antiquity to modern art.
Archaeological museum on Fourvière Hill with Roman mosaics, inscriptions, and access to the adjacent ancient theatres.
One of Europe’s largest open squares, a central meeting point and starting place for exploring Lyon.
Lyon’s flagship urban park with a lake, botanical gardens, rose garden, and broad walking paths.
The central peninsula between the Rhône and Saône, packed with shopping streets, squares, and grand architecture.
Light dumplings traditionally made with pike and served with a rich Nantua crayfish sauce, a classic of Lyonnais cooking.
A warm salad with frisée, lardons, croutons, and a poached egg, widely associated with Lyon's bouchon tradition.
A robust sausage made from pork tripe, famous in Lyon for its strong flavor and served in many traditional bouchons.
Historic fine-dining institution in Lyon, renowned for haute cuisine rooted in the legacy of Eugénie Brazier.
Popular modern bouchon offering refined Lyonnais classics in a warm, intimate setting.
Classic bouchon known for traditional Lyonnais dishes, hearty set menus, and a lively, old-school atmosphere.
Moderate by French standards: bakeries and bouchons are reasonable, while hotels and fine dining cost more.
Service is included in restaurant bills. Leaving 5-10% for great service is appreciated but not required. Round up for taxis; small change for cafés is optional.
Official public transport app
Lyon Perrache Bus Station -> Lyon Part-Dieu Station
Buses in Europe are an affordable way to travel between cities, with a number of bus companies offering both domestic and international routes. Buses from Milan to Lyon are operated by Flixbus, Ouibus, and Baltour with daily departures from around 9:00 a.m., until just after 11:00 p.m. Flixbus operates approximately 5 direct buses per day, with a journey time of approximately 6:45 h.
Return buses from Lyon to Milan | Compare all modes of traveling from Milan to Lyon | Or learn more about buses to Lyon
Average prices for buses from Milan to Lyon when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€40 |
1 Day in Advance |
€36 |
1 Week in Advance |
€25 |
2 Weeks in Advance |
€25 |
1 Month in Advance |
€25 |
3 Months in Advance |
€25 |
Milan to Lyon Buses: General Information
Buses traveling from Milan to Lyon are usually cheaper than taking a flight or the train, taking at least 6½ hours to arrive Lyon.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Milan to Lyon buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Milan to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need