- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
Kč1132
Average price
Kč1739
Fastest journey
6 h 10 m
Average duration
6 h 16 m
Buses per day
23
Distance
339 km
The best way to find a cheap bus ticket from Milan to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Lyon will cost around Kč1739 if you buy it on the day, but the cheapest tickets can be found for only Kč1132.
Of the 23 buses that leave Milan for Lyon on Thu, Aug 20, 19 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 20 the direct buses cover the 339 km distance in an average of 6 h 16 m but if you time it right, some buses will get you there in just 6 h 10 m .
On Thu, Aug 20 the slowest buses will take 6 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1716 · 80014
FlixBus
3492
FlixBus
FlixBus
FlixBus
4782
FlixBus
FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Milan to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from Kč309. For those with little time consider booking a flight which can get you there in 2h 34m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of Kč309, and a flight costs an average of Kč2486.
Distance: 210 miles (339 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
Kč667 Average price Cheapest | Kč2676 Average price | Kč6145 Average price | Kč5101 Average price (fuel + tolls) |
7h 14m Average total duration 6h 44m Onboard + 30m Additional time* | 6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 5h 34m Average total duration Fastest 2h 34m Onboard + 3h 0m Additional time* | 5h 17m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Lyon:
A bus is Kč2411 less than a train for this route with tickets for a train from Milan to Lyon costing on average Kč3082.
A bus is Kč4221 less than a flight for this route with tickets for a flight from Milan to Lyon costing on average Kč4892.
Other travel options to Lyon take longer:
Train takes on average 6h 18m.
Bus takes on average 6h 44m.
Tickets start at around Kč671 compared to roughly Kč5101 in fuel and tolls — a saving of about Kč4430. The journey takes 6h 44m versus 5h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, FlixBus, Itabus, Union Ivkoni International, BlaBlaCar, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:30AM | Arrival Time 08:45AM | Duration 8h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč1351 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 12:00PM | Duration 6h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč797 |
Operator Itabus | Departure Time 06:20AM | Arrival Time 01:00PM | Duration 6h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price Kč772 |
Operator BlaBlaCar | Departure Time 06:40AM | Arrival Time 12:30PM | Duration 5h50 | Departure days Fri | Cheapest price Kč769 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 02:10PM | Duration 6h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč797 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 01:10PM | Duration 5h10 | Departure days Sun | Cheapest price Kč1027 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 03:05PM | Duration 6h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč823 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 04:25PM | Duration 7h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč772 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 02:40PM | Duration 5h00 | Departure days Fri | Cheapest price Kč1027 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 03:00PM | Duration 5h10 | Departure days Fri | Cheapest price Kč1027 |
Operator BlaBlaCar | Departure Time 10:10AM | Arrival Time 03:20PM | Duration 5h10 | Departure days Fri | Cheapest price Kč769 |
Operator BlaBlaCar Bus | Departure Time 10:20AM | Arrival Time 05:05PM | Duration 6h45 | Departure days Fri, Sat, Sun | Cheapest price Kč1287 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 10:40PM | Duration 12h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč2007 |
Operator BlaBlaCar Bus | Departure Time 10:35AM | Arrival Time 06:55PM | Duration 8h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price Kč1003 |
Operator BlaBlaCar Bus | Departure Time 11:35AM | Arrival Time 07:35PM | Duration 8h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč1287 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 05:40PM | Duration 5h40 | Departure days Tue, Sat | Cheapest price Kč1027 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 06:40PM | Duration 6h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč823 |
Operator Itabus | Departure Time 02:55PM | Arrival Time 09:30PM | Duration 6h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč669 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 08:20PM | Duration 5h20 | Departure days Sun | Cheapest price Kč1055 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 09:10PM | Duration 6h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč1209 |
Operator BlaBlaCar Bus | Departure Time 04:00PM | Arrival Time 10:55PM | Duration 6h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč772 |
Operator Itabus | Departure Time 05:50PM | Arrival Time 12:25AM | Duration 6h35 | Departure days Everyday | Cheapest price Kč669 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 11:00PM | Duration 5h00 | Departure days Fri | Cheapest price Kč1122 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:35AM | Duration 6h35 | Departure days Everyday | Cheapest price Kč797 |
Operator BlaBlaCar Bus | Departure Time 06:50PM | Arrival Time 01:20AM | Duration 6h30 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price Kč1415 |
Operator BlaBlaCar Bus | Departure Time 08:00PM | Arrival Time 02:15AM | Duration 6h15 | Departure days Everyday | Cheapest price Kč772 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:45AM | Duration 11h45 | Departure days Everyday | Cheapest price Kč1724 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 03:55AM | Duration 6h20 | Departure days Everyday | Cheapest price Kč875 |
Operator Itabus | Departure Time 10:25PM | Arrival Time 04:55AM | Duration 6h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price Kč1544 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 04:50AM | Duration 6h20 | Departure days Everyday | Cheapest price Kč1544 |
Operator BlaBlaCar Bus | Departure Time 11:35PM | Arrival Time 06:45AM | Duration 7h10 | Departure days Everyday | Cheapest price Kč772 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 06:30AM | Duration 6h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price Kč1003 |
The table below shows live departures for Milan to Lyon buses for today, Wednesday, August 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
3092 | 5:50 PM Milano, Autostazione Lampugnano | 6h35 | 12:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 6:00 PM Milano, Autostazione Lampugnano | 6h35 | 12:35 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
94742 | 6:50 PM Milano, Autostazione Lampugnano | 6h30 | 1:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4782 | 8:00 PM Milano, Autostazione Lampugnano | 6h15 | 2:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 9:00 PM Milano, Milan Linate Airport | 11h45 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 9:35 PM Milano, Autostazione Lampugnano | 6h20 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 10:30 PM Milano, Autostazione Lampugnano | 6h20 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4768 | 11:35 PM Milano, Autostazione Lampugnano | 7h10 | 6:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:45 PM Milano, Autostazione Lampugnano | 6h45 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Thursday, August 20 | |||||
FlixBus · FlixBus | 12:30 AM Milano, Autostazione Lampugnano | 8h15 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 5:45 AM Milano, Autostazione Lampugnano | 6h15 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:30 AM Milano, Autostazione Lampugnano | 6h40 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 8:30 AM Milano, Autostazione Lampugnano | 6h35 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 9:15 AM Milano, Autostazione Lampugnano | 7h10 | 4:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 12h20 | 10:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1716 · 80014 | 10:35 AM Milano, Autostazione Lampugnano | 8h20 | 6:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1716 | 10:35 AM Milano, Autostazione Lampugnano | 8h15 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
1726 | 11:35 AM Milano, Autostazione Lampugnano | 8h00 | 7:35 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 12:05 PM Milano, Autostazione Lampugnano | 6h35 | 6:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
3492 | 2:55 PM Milano, Autostazione Lampugnano | 6h35 | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 6h10 | 9:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4750 | 4:00 PM Milano, Autostazione Lampugnano | 6h55 | 10:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Lyon run on average 22 times per day, taking around 6h 44m. Cheap bus tickets for this journey start at Kč309 if you book in advance.
There are 17 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 210 miles (339 km) distance in 6h 20m.
Distance 210 miles (339 km) |
Average bus duration 6h 44m |
Cheapest ticket price Kč309 |
Buses per day 22 |
Direct buses 17 |
Fastest bus 6h 20m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Buses in Europe are an affordable way to travel between cities, with a number of bus companies offering both domestic and international routes. Buses from Milan to Lyon are operated by Flixbus, Ouibus, and Baltour with daily departures from around 9:00 a.m., until just after 11:00 p.m. Flixbus operates approximately 5 direct buses per day, with a journey time of approximately 6:45 h.
Return buses from Lyon to Milan | Compare all modes of traveling from Milan to Lyon | Or learn more about buses to Lyon
Average prices for buses from Milan to Lyon when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€40 |
1 Day in Advance |
€36 |
1 Week in Advance |
€25 |
2 Weeks in Advance |
€25 |
1 Month in Advance |
€25 |
3 Months in Advance |
€25 |
Milan to Lyon Buses: General Information
Buses traveling from Milan to Lyon are usually cheaper than taking a flight or the train, taking at least 6½ hours to arrive Lyon.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Milan to Lyon buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Milan to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Milan to Lyon buses use the Milano, Autostazione Lampugnano to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Milan and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Here are some other resources that might have the information you need