- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.






Cheapest price
$61
Average price
$129
Fastest journey
28h 0m
Average duration
36h 33m
Buses per day
6
Distance
311 km
Omio recommends booking the flight as it is the most popular option from Seville to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $46. For those with little time consider booking a flight which can get you there in 3h 16m. The ticket price range depends on the travel mode: a bus costs an average of $46, and a flight costs an average of $62.
Distance: 802 miles (1292 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$144 Average price Cheapest | $216 Average price | $179 Average price | $327 Average price (fuel + tolls) |
25h 18m Average total duration 24h 48m Onboard + 30m Additional time* | 6h 16m Average total duration Fastest 3h 16m Onboard + 3h 0m Additional time* | 28h 58m Average total duration 28h 28m Onboard + 30m Additional time* | 16h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Seville to Lyon:
A bus is $35 (€29) less than a train for this route with tickets for a train from Seville to Lyon costing on average $179 (€147).
A bus is $72 (€59) less than a flight for this route with tickets for a flight from Seville to Lyon costing on average $216 (€177).
Other travel options to Lyon take longer:
Bus takes on average 24h 48m.
Train takes on average 28h 28m.
Tickets start at around $144 (€118) compared to roughly $327 (€268) in fuel and tolls — a saving of about $183 (€150). The journey takes 24h 48m versus 16h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 10:50AM | Duration 34h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $96 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 05:30PM | Duration 33h40 | Departure days Everyday | Cheapest price $98 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 01:50AM | Duration 17h50 | Departure days Sat | Cheapest price $216 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 11:15PM | Duration 34h20 | Departure days Everyday | Cheapest price $98 |
Operator Alsa | Departure Time 10:00PM | Arrival Time 02:00AM | Duration 28h00 | Departure days Tue, Thu, Sat | Cheapest price $61 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 10:50AM | Duration 34h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $117 |
The table below shows live departures for Seville to Lyon buses for today, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:50 AM Sevilla, Estación de Autobuses (Plaza de Armas) | 33h40 | 5:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 7:50 AM Sevilla, Estación de Autobuses (Plaza de Armas) | 43h05 | 2:55 AM Lyon | 3 transfers | |
FlixBus · FlixBus · FlixBus | 12:55 PM Sevilla, Estación de Autobuses (Plaza de Armas) | 39h40 | 4:35 AM Lyon | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:55 PM Sevilla, Estación de Autobuses (Plaza de Armas) | 39h55 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
Normal · Normal · Normal | 10:00 PM Sevilla, Estación de Autobuses (Plaza de Armas) | 28h00 | 2:00 AM Lyon, Perrache Bus Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:55 PM Sevilla, Estación de Autobuses (Plaza de Armas) | 34h55 | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
| Friday, July 17 | |||||
FlixBus · FlixBus | 12:15 AM Sevilla, Estación de Autobuses (Plaza de Armas) | 34h35 | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Seville to Lyon run on average 2 times per day, taking around 24h 48m. Cheap bus tickets for this journey start at $46 (€38) if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 802 miles (1292 km) distance in 27h 0m.
Distance 802 miles (1292 km) |
Average bus duration 24h 48m |
Cheapest ticket price $46 (€38) |
Buses per day 2 |
Fastest bus 27h 0m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Sun |
Best time to book 7 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Seville to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Seville to Lyon buses use the Sevilla, Estación de Autobuses (Plaza de Armas) to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan). Use this guide to compare Seville and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Sevilla, Estación de Autobuses (Plaza de Armas) is 2 km from Seville city centre. Public transport options include:
Sevilla, Estación de Autobuses (Plaza de Armas) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante La Azotea (0.5 km), Bar El Comercio (0.7 km).
Free Wi-Fi. ATMs are located near the entrance and in the main hall.
Ticket office support is available at Sevilla, Estación de Autobuses (Plaza de Armas).
Available at Sevilla, Estación de Autobuses (Plaza de Armas): Parking, Taxis, WC.
Accessibility facilities are available at Sevilla, Estación de Autobuses (Plaza de Armas): Elevators, ramps.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
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