- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$65
Average price
$125
Fastest journey
1 d 4 h
Average duration
1 d 6 h 50 m
Buses per day
2
Distance
1292 km
The best way to find a cheap bus ticket from Seville to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Seville to Lyon will cost around $125 if you buy it on the day, but the cheapest tickets can be found for only $65.
It's difficult to get from Seville to Lyon without transferring at least once.
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FlixBus · FlixBus
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FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Seville to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $47. For those with little time consider booking a flight which can get you there in 3h 16m. The ticket price range depends on the travel mode: a bus costs an average of $47, and a flight costs an average of $63.
Distance: 802 miles (1292 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$147 Average price Cheapest | $220 Average price | $183 Average price | $333 Average price (fuel + tolls) |
25h 18m Average total duration 24h 48m Onboard + 30m Additional time* | 6h 16m Average total duration Fastest 3h 16m Onboard + 3h 0m Additional time* | 28h 58m Average total duration 28h 28m Onboard + 30m Additional time* | 16h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Seville to Lyon:
A bus is $36 (€29) less than a train for this route with tickets for a train from Seville to Lyon costing on average $183 (€147).
A bus is $73 (€59) less than a flight for this route with tickets for a flight from Seville to Lyon costing on average $220 (€177).
Other travel options to Lyon take longer:
Bus takes on average 24h 48m.
Train takes on average 28h 28m.
Tickets start at around $147 (€118) compared to roughly $333 (€268) in fuel and tolls — a saving of about $186 (€150). The journey takes 24h 48m versus 16h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:50AM | Arrival Time 05:30PM | Duration 33h40 | Departure days Everyday | Cheapest price $139 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 07:45AM | Duration 42h50 | Departure days Thu, Fri, Sat, Sun | Cheapest price $138 |
Operator Alsa | Departure Time 10:00PM | Arrival Time 02:00AM | Duration 28h00 | Departure days Tue, Thu, Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 10:50AM | Duration 34h55 | Departure days Mon, Wed, Fri | Cheapest price $156 |
The table below shows live departures for Seville to Lyon buses for today, Monday, June 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:50 AM Sevilla, Estación de Autobuses (Plaza de Armas) | 33h40 | 5:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:55 PM Sevilla, Estación de Autobuses (Plaza de Armas) | 34h55 | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Seville to Lyon run on average 2 times per day, taking around 24h 48m. Cheap bus tickets for this journey start at $47 (€38) if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 802 miles (1292 km) distance in 27h 0m.
Distance 802 miles (1292 km) |
Average bus duration 24h 48m |
Cheapest ticket price $47 (€38) |
Buses per day 2 |
Fastest bus 27h 0m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Sun |
Best time to book 7 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
Find answers to the most common questions about traveling from Seville to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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