The cheapest and fastest buses from Rome to Lyon
Cheapest price
$55
Average price
$111
Fastest journey
14 h 30 m
Average duration
14 h 46 m
Buses per day
15
Distance
747 km
The best way to find a cheap bus ticket from Rome to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Lyon will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $55.
Of the 15 buses that leave Rome for Lyon on Sun, Mar 01, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 01 the direct buses cover the 747 km distance in an average of 14 h 46 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Sun, Mar 01 the slowest buses will take 14 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2126 · 3092
3898
3492
FlixBus · FlixBus
FlixBus · FlixBus
3492
FlixBus · FlixBus
4788
FlixBus
FlixBusTravel Information
Compare train, bus, and flight for Rome to Lyon
Omio recommends booking the flight as it is the most popular option from Rome to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a flight which can get you there in 2h 51m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a flight costs an average of $63.
Distance: 464 miles (747 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$58 Average price Cheapest | $184 Average price | $152 Average price |
14h 48m Average total duration 14h 18m Onboard + 30m Additional time* | 5h 51m Average total duration Fastest 2h 51m Onboard + 3h 0m Additional time* | 9h 51m Average total duration 9h 21m Onboard + 30m Additional time* |
0.7 - 1.9kg CO2 emissions Lowest | 2.2 - 4.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:10AM | Arrival Time 04:25PM | Duration 16h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 12:15AM | Arrival Time 09:10PM | Duration 20h55 | Departure days Mon, Thu, Fri | Cheapest price $81 |
Operator Itabus | Departure Time 07:00AM | Arrival Time 09:30PM | Duration 14h30 | Departure days Wed, Thu, Fri, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 10:40PM | Duration 14h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $54 |
Operator Itabus | Departure Time 08:00AM | Arrival Time 12:25AM | Duration 16h25 | Departure days Thu, Fri, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 11:45PM | Duration 14h55 | Departure days Everyday | Cheapest price $60 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 05:15AM | Duration 17h05 | Departure days Wed, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 06:30AM | Duration 18h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $77 |
Operator Regiojet | Departure Time 01:00PM | Arrival Time 02:50PM | Duration 49h50 | Departure days Wed | Cheapest price $174 |
Operator Itabus | Departure Time 01:00PM | Arrival Time 04:55AM | Duration 15h55 | Departure days Thu, Fri | Cheapest price $35 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 03:50AM | Duration 14h45 | Departure days Everyday | Cheapest price $69 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 06:05AM | Duration 14h45 | Departure days Wed, Thu, Sat, Sun | Cheapest price $58 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 08:45AM | Duration 16h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 08:45AM | Duration 15h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 12:00PM | Duration 16h00 | Departure days Everyday | Cheapest price $64 |
Operator Itabus | Departure Time 09:45PM | Arrival Time 12:55PM | Duration 15h10 | Departure days Everyday | Cheapest price $33 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 02:10PM | Duration 16h15 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 03:05PM | Duration 16h20 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $64 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:05PM | Duration 15h30 | Departure days Fri, Sat | Cheapest price $86 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 09:10PM | Duration 21h20 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $77 |
Live departures
Rome to Lyon bus times
The table below shows live departures for Rome to Lyon buses for today, Saturday, February 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 16h00 | 11:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
3898 | 8:45 PM Roma, Autostazione Tiburtina | 15h10 | 11:55 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 16h15 | 1:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 16h20 | 2:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:35 PM Roma, Autostazione (Metro Anagnina) | 15h30 | 2:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 2 transfers | |
FlixBus · FlixBus | 11:10 PM Roma, Autostazione Tiburtina | 16h15 | 3:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
| Sunday, March 1 | |||||
3492 | 6:00 AM Roma, Autostazione Tiburtina | 14h30 | 8:30 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus | 6:45 AM Roma, Autostazione Tiburtina | 14h55 | 9:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 0 transfersDirect | |
2126 · 3092 | 7:00 AM Roma, Autostazione Tiburtina | 16h25 | 11:25 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 7:50 AM Roma, Autostazione Tiburtina | 14h55 | 10:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 0 transfersDirect | |
FlixBus · FlixBus | 11:10 AM Roma, Autostazione Tiburtina | 17h05 | 4:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 18h10 | 5:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 14h45 | 2:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
4788 | 2:20 PM Roma, Autostazione Tiburtina | 14h45 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 0 transfersDirect | |
FlixBus · FlixBus | 3:00 PM Roma, Autostazione Tiburtina | 16h45 | 7:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 15h20 | 7:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Why should you book Rome to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus, Itabus or Infobus to find the best option for your trip from Rome to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus, Itabus or Infobus to find the best option for your trip from Rome to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Lyon.
Journey information
Overview: Bus from Rome to Lyon
Buses from Rome to Lyon run on average 13 times per day, taking around 14h 18m. Cheap bus tickets for this journey start at $26 (€21) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:04, the last at 23:50. The fastest bus covers the 464 miles (747 km) distance in 14h 30m.
Distance 464 miles (747 km) |
Average bus duration 14h 18m |
Cheapest ticket price $26 (€21) |
Buses per day 13 |
Direct buses 5 |
Fastest bus 14h 30m |
First bus 00:04 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar Bus, Itabus, BlaBlaCar, Infobus from Rome to LyonYou can travel by bus between Rome to Lyon with FlixBus, BlaBlaCar Bus, Itabus, BlaBlaCar, Infobus for as low as $26 (€21). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Infobus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Rome to Lyon
Find answers to the most common questions about traveling from Rome to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Rome to Lyon
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
More options for your journey from Rome to Lyon
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