- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
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The cheapest and fastest buses from Rome to Lyon
Showing times and prices for May 31
Cheapest price
$37
Average price
$88
Fastest journey
14 h 30 m
Average duration
14 h 47 m
Buses per day
18
Distance
747 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Lyon will cost around $88 if you buy it on the day, but the cheapest tickets can be found for only $37.
Fast buses
Of the 18 buses that leave Rome for Lyon on Sun, May 31, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, May 31 the direct buses cover the 747 km distance in an average of 14 h 47 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Sun, May 31 the slowest buses will take 14 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
34927:00 AM14h30Roma, Autostazione Tiburtina9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$371One-way0 transfers- 38989:45 PM15h10Roma, Autostazione Tiburtina12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$421One-way0 transfers
FlixBus8:50 AM14h55Roma, Autostazione Tiburtina11:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way0 transfers- FlixBus5:25 PM15h20Roma, Autostazione (Metro Anagnina)8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way0 transfers
- 3804 · 30901:00 PM15h55Roma, Autostazione Tiburtina4:55 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way1 transfer
- 34927:00 AM14h30Roma, Autostazione Tiburtina9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$371One-way0 transfers
47883:20 PM14h45Roma, Autostazione Tiburtina6:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$531One-way0 transfers- FlixBus · FlixBus1:05 PM14h50Roma, Autostazione (Metro Anagnina)3:55 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1121One-way1 transfer
- FlixBus7:45 AM14h55Roma, Autostazione Tiburtina10:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$931One-way0 transfers
- FlixBus8:50 AM14h55Roma, Autostazione Tiburtina11:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way0 transfers
Travel Information
Compare bus, flight, and train for Rome to Lyon
Omio recommends booking the bus as it is the most popular option from Rome to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a flight which can get you there in 4h 7m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $78.
Distance: 464 miles (747 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$55 Average price Cheapest | $200 Average price | $165 Average price | $400 Average price (fuel + tolls) |
13h 0m Average total duration 12h 30m Onboard + 30m Additional time* | 7h 7m Average total duration Fastest 4h 7m Onboard + 3h 0m Additional time* | 9h 46m Average total duration 9h 16m Onboard + 30m Additional time* | 9h 55m Average total duration (door-to-door) |
0.7 - 1.9kg CO2 emissions Lowest | 2.2 - 4.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Lyon is a bus with an average price of $55 (€44).
This is compared to other travel options from Rome to Lyon:
A bus is $110 (€88) less than a train for this route with tickets for a train from Rome to Lyon costing on average $165 (€133).
A bus is $145 (€117) less than a flight for this route with tickets for a flight from Rome to Lyon costing on average $200 (€161).
The fastest way to travel from Rome to Lyon is by flight with an average journey time of 4h 7m.
Other travel options to Lyon take longer:
Train takes on average 9h 16m.
Bus takes on average 12h 30m.
It's helpful to compare your options as there are 3 ways to travel between Rome and Lyon including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from Rome to Lyon among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $55 (€44) compared to roughly $400 (€322) in fuel and tolls — a saving of about $345 (€278). The journey takes 12h 30m versus 9h 55m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rome to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 06:10PM | Duration 16h50 | Departure days Everyday | Cheapest price $86 |
Operator Itabus | Departure Time 07:00AM | Arrival Time 09:30PM | Duration 14h30 | Departure days Everyday | Cheapest price $37 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 10:40PM | Duration 14h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator Itabus | Departure Time 08:00AM | Arrival Time 12:25AM | Duration 16h25 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 11:45PM | Duration 14h55 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 03:55AM | Duration 16h45 | Departure days Fri | Cheapest price $89 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 04:50AM | Duration 16h40 | Departure days Sat, Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 07:45AM | Duration 19h25 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $86 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 02:50PM | Duration 49h50 | Departure days Wed | Cheapest price $161 |
Operator Itabus | Departure Time 01:00PM | Arrival Time 04:55AM | Duration 15h55 | Departure days Thu, Fri, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 03:55AM | Duration 14h50 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 06:30AM | Duration 15h45 | Departure days Sun | Cheapest price $104 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 06:05AM | Duration 14h45 | Departure days Wed, Thu, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 08:45AM | Duration 15h40 | Departure days Everyday | Cheapest price $84 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 08:45AM | Duration 15h20 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 12:00PM | Duration 16h00 | Departure days Everyday | Cheapest price $69 |
Operator Itabus | Departure Time 09:45PM | Arrival Time 12:55PM | Duration 15h10 | Departure days Everyday | Cheapest price $42 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 02:10PM | Duration 16h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 03:05PM | Duration 16h20 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 04:25PM | Duration 16h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $104 |
Live departures
Rome to Lyon bus times
The table below shows live departures for Rome to Lyon buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 8:50 AM Roma, Autostazione Tiburtina | 14h55 | 11:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 8:50 AM Roma, Autostazione Tiburtina | 17h35 | 2:25 AM Lyon | 2 transfers | |
| FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 16h40 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 18h10 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 14h50 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| 4788 | 3:20 PM Roma, Autostazione Tiburtina | 14h45 | 6:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 15h40 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 15h20 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 16h00 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| 3898 | 9:45 PM Roma, Autostazione Tiburtina | 15h10 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus · FlixBus | 9:55 PM Roma, Autostazione Tiburtina | 16h15 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 16h20 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 15h30 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
| Sunday, May 31 | |||||
| FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 16h50 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| 3492 | 7:00 AM Roma, Autostazione Tiburtina | 14h30 | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus | 7:45 AM Roma, Autostazione Tiburtina | 14h55 | 10:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| 2126 · 3092 | 8:00 AM Roma, Autostazione Tiburtina | 16h25 | 12:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Lyon by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Lyon buses with Omio?
Itabus as well as FlixBus, BlaBlaCar Bus, Infobus and more offer buses services from Rome to Lyon.
Omio is an official ticket reseller for all your travel options from Rome to Lyon.
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Infobus to find the best option for your trip from Rome to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Rome to Lyon.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Infobus to find the best option for your trip from Rome to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Rome to Lyon.
Journey information
Overview: Bus from Rome to Lyon
Italy
France
Buses from Rome to Lyon run on average 14 times per day, taking around 12h 30m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:04, the last at 23:50. The fastest bus covers the 464 miles (747 km) distance in 14h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 464 miles (747 km) |
Average bus duration 12h 30m |
Cheapest ticket price $22 (€18) |
Buses per day 14 |
Direct buses 5 |
Fastest bus 14h 30m |
First bus 12:04 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus from Rome to LyonYou can travel by bus between Rome to Lyon with Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus for as low as $22 (€18). When you search for schedules and tickets, Omio will show you the best journey
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
14h 30m
Cheapest Price
$22 (€18)
Itabus frequency
4 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 55m
Cheapest Price
$37 (€30)
FlixBus frequency
12 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Duration
14h 30m
Cheapest Price
$60 (€48)
Infobus frequency
2 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
14h 45m
Cheapest Price
$45 (€36)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
1 a day
Complete guide to Lyon
Things to do in Lyon
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
- Must visit
Musée des Beaux-Arts de Lyon
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
- Recommended
Lugdunum - Musée et Théâtres romains
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
- Must visit
Vieux Lyon
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
- Must visit
Place Bellecour
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
- Must visit
Parc de la Tête d'Or
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Quenelles De Brochet
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
Salade Lyonnaise
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Saucisson Brioché
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
La Mère Brazier
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
Les Halles De Lyon Paul Bocuse
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
Daniel Et Denise
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Euro
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 10-15 for a bakery lunch or kebab.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 2.50-4 for an espresso or cappuccino.
Tipping culture
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
TCL: Itinéraires & Tickets
Get the appOfficial public transport app
Prices
- Single ticket
- 2.00 EUR
- Day pass
- 6.70 EUR
To the city center
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
- Distance
- 4 km
- Travel time
- 15 min
- You can buy tickets in the official TCL app, at ticket machines, or at metro and tram stops. Contactless bank card payment is available on TCL buses and trams.
- Validate your ticket when boarding or entering the network, and keep it until the end of your journey. A Day Pass is usually best value if you plan several trips in one day.
FAQs: Bus from Rome to Lyon
Find answers to the most common questions about traveling from Rome to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Lyon can start from as little as $22 (€18) when you book in advance. The average bus ticket price for Rome to Lyon is $55 (€44) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Lyon is 14h 30m to travel the 464 miles (747 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Lyon leaves at 12:04 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Lyon leaves at 11:50 PM.
Yes, there are 5 direct buses a day from Rome to Lyon with Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Lyon, you can count on Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus for the best way to get you to Lyon. You can also check all possible bus companies who offer a service between Rome and Lyon and compare the amenities they offer before buying a bus ticket.
A trip to Lyon from Rome is worth doing but not as a day trip with a journey time of 14h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Lyon is February.
It's helpful to compare your options as there are 3 ways to travel between Rome and Lyon including taking a bus, flight, and train.
Yes, there are bathrooms on board the bus from Rome to Lyon for bus company Itabus, FlixBus, BlaBlaCar Bus, Infobus.
Yes, the following accessibility options are available when taking the bus from Rome to Lyon:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Some of the most interesting sights to explore in Lyon are:
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
The best things to do in Lyon include:
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
Whether you can cancel your bus ticket from Rome to Lyon depends on the bus companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company Itabus, FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Lyon.
Yes, the following luggage options are included when booking a bus ticket from Rome to Lyon:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Lyon:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Rome to Lyon. The following conditions apply:
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Rome to Lyon with the following bus company: Itabus, FlixBus, BlaBlaCar Bus, Infobus
Yes, there are USB plugs on board the bus from Rome to Lyon with the following bus company: Itabus, FlixBus, BlaBlaCar Bus, Infobus.
Yes, there is Wifi on board the bus from Rome to Lyon with the following bus company: Itabus, FlixBus, BlaBlaCar Bus, Infobus.
Since both Rome and Lyon are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Rome to Lyon among Omio's users.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
In Lyon, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, popular tourist spots, and markets. Common scams include distraction techniques and fake charity collectors. It's advisable to keep valuables secure and be wary of overly friendly strangers offering unsolicited help. Avoid unlicensed taxi services to prevent overcharging. Staying alert in busy zones ensures a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Lyon
Rome
Lyon
The major bus station for departures in Rome is Roma, Autostazione Tiburtina. Find all the information you need to know about services, amenities and connections at Roma, Autostazione Tiburtina for your trip from Rome to Lyon.
Roma, Autostazione Tiburtina
information
Roma, Autostazione (Metro Anagnina)
information
Roma
information
The major bus station for arrivals in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip to Lyon from Rome.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
information
Lyon, Gare Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
Cours de Verdun RambaudWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available on the concourse.
Public transit options for Lyon, Gare Perrache
- Bus: C21, C22, S1 Metro: A Train: TER
More options for your journey from Rome to Lyon
Here are some other resources that might have the information you need
Most popular buses to and from Lyon and Rome
Most popular bus connections to Lyon
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