- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$48
Average price
$79
Fastest journey
16 h
Average duration
16 h 40 m
Buses per day
11
Distance
912 km
The best way to find a cheap bus ticket from Madrid to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Lyon will cost around $79 if you buy it on the day, but the cheapest tickets can be found for only $48.
Of the 11 buses that leave Madrid for Lyon on Wed, May 27, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, May 27 the direct buses cover the 912 km distance in an average of 16 h 40 m but if you time it right, some buses will get you there in just 16 h .
On Wed, May 27 the slowest buses will take 17 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Normal · Normal
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54152
3187
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FlixBus
3187
Normal · NormalOmio recommends booking the bus as it is the most popular option from Madrid to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 5h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $43.
Distance: 566 miles (912 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$75 Average price Cheapest | $234 Average price | $145 Average price | $244 Average price (fuel + tolls) |
15h 52m Average total duration 15h 22m Onboard + 30m Additional time* | 8h 9m Average total duration Fastest 5h 9m Onboard + 3h 0m Additional time* | 8h 42m Average total duration 8h 12m Onboard + 30m Additional time* | 12h 21m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Lyon:
A bus is $70 (€57) less than a train for this route with tickets for a train from Madrid to Lyon costing on average $145 (€117).
A bus is $160 (€129) less than a flight for this route with tickets for a flight from Madrid to Lyon costing on average $234 (€189).
Other travel options to Lyon take longer:
Train takes on average 8h 12m.
Bus takes on average 15h 22m.
Tickets start at around $75 (€60) compared to roughly $244 (€197) in fuel and tolls — a saving of about $170 (€137). The journey takes 15h 22m versus 12h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, Alsa, FlixBus, Union Ivkoni International, Internorte, Union Ivkoni.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 06:30AM | Arrival Time 01:10AM | Duration 18h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $68 |
Operator BlaBlaCar Bus | Departure Time 08:35AM | Arrival Time 01:55AM | Duration 17h20 | Departure days Wed, Fri, Sun | Cheapest price $56 |
Operator | Departure Time 10:00AM | Arrival Time 04:45AM | Duration 18h45 | Departure days Fri, Sun | Cheapest price $114 |
Operator Alsa | Departure Time 11:00AM | Arrival Time 10:14AM | Duration 23h14 | Departure days Fri | Cheapest price $87 |
Operator Alsa | Departure Time 11:15AM | Arrival Time 04:05AM | Duration 16h50 | Departure days Thu, Fri | Cheapest price $56 |
Operator Alsa | Departure Time 11:55AM | Arrival Time 05:15AM | Duration 17h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $48 |
Operator Alsa | Departure Time 01:00PM | Arrival Time 10:14AM | Duration 21h14 | Departure days Fri | Cheapest price $87 |
Operator Alsa | Departure Time 01:15PM | Arrival Time 05:15AM | Duration 16h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 10:50AM | Duration 20h00 | Departure days Thu, Sat | Cheapest price $144 |
Operator Alsa | Departure Time 03:00PM | Arrival Time 10:14AM | Duration 19h14 | Departure days Fri | Cheapest price $114 |
Operator Alsa | Departure Time 03:15PM | Arrival Time 10:14AM | Duration 18h59 | Departure days Fri | Cheapest price $115 |
Operator BlaBlaCar Bus | Departure Time 03:30PM | Arrival Time 02:40PM | Duration 23h10 | Departure days Thu, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 10:50AM | Duration 18h55 | Departure days Thu, Sat | Cheapest price $142 |
Operator BlaBlaCar Bus | Departure Time 06:35PM | Arrival Time 06:50PM | Duration 24h15 | Departure days Mon | Cheapest price $84 |
Operator BlaBlaCar Bus | Departure Time 08:30PM | Arrival Time 01:40PM | Duration 17h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $68 |
Operator Internorte | Departure Time 08:30PM | Arrival Time 01:40PM | Duration 17h10 | Departure days Thu | Cheapest price $61 |
Operator Alsa | Departure Time 08:30PM | Arrival Time 01:40PM | Duration 17h10 | Departure days Thu | Cheapest price $61 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 01:30PM | Duration 16h40 | Departure days Everyday | Cheapest price $74 |
Operator Internorte | Departure Time 08:55PM | Arrival Time 01:40PM | Duration 16h45 | Departure days Thu | Cheapest price $61 |
Operator Alsa | Departure Time 08:55PM | Arrival Time 01:40PM | Duration 16h45 | Departure days Thu | Cheapest price $61 |
Operator BlaBlaCar Bus | Departure Time 10:30PM | Arrival Time 06:10PM | Duration 19h40 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $85 |
Operator BlaBlaCar Bus | Departure Time 11:00PM | Arrival Time 08:00PM | Duration 21h00 | Departure days Wed, Fri, Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 05:30PM | Duration 17h55 | Departure days Everyday | Cheapest price $74 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 05:30PM | Duration 17h31 | Departure days Everyday | Cheapest price $76 |
The table below shows live departures for Madrid to Lyon buses for today, Tuesday, May 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 8:50 PM Madrid, Estación Sur de Autobuses | 16h40 | 1:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:35 PM Madrid, Estación Sur de Autobuses | 17h55 | 5:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:59 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 17h31 | 5:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Wednesday, May 27 | |||||
54152 | 8:35 AM Madrid, Estación Sur de Autobuses | 17h20 | 1:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Normal · Normal | 11:55 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 17h20 | 5:15 AM Lyon, Perrache Bus Station | 1 transfer | |
Normal · Normal | 11:55 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 16h10 | 4:05 AM Lyon, Perrache Bus Station | 1 transfer | |
Normal · Normal | 1:15 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 16h00 | 5:15 AM Lyon, Perrache Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Madrid to Lyon run on average 11 times per day, taking around 15h 22m. Cheap bus tickets for this journey start at $32 (€26) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:14, the last at 23:50. The fastest bus covers the 566 miles (912 km) distance in 15h 10m.
Distance 566 miles (912 km) |
Average bus duration 15h 22m |
Cheapest ticket price $32 (€26) |
Buses per day 11 |
Direct buses 3 |
Fastest bus 15h 10m |
First bus 12:14 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 56 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Perrache Bus Station -> Lyon Part-Dieu Station
Find answers to the most common questions about traveling from Madrid to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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