- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities, and decorative arts.
Cheapest price
$38
Average price
$87
Fastest journey
9 h 35 m
Average duration
10 h 22 m
Buses per day
14
Distance
563 km
The best way to find a cheap bus ticket from Frankfurt am Main to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Lyon will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $38.
Of the 14 buses that leave Frankfurt am Main for Lyon on Thu, Jul 09, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 09 the direct buses cover the 563 km distance in an average of 10 h 22 m but if you time it right, some buses will get you there in just 9 h 35 m .
On Thu, Jul 09 the slowest buses will take 11 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
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51510
FlixBusOmio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $29. For those with little time consider booking a flight which can get you there in 1h 57m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $29, and a flight costs an average of $167.
Distance: 349 miles (563 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$54 Average price Cheapest | $193 Average price | $391 Average price | $177 Average price (fuel + tolls) |
10h 35m Average total duration 10h 5m Onboard + 30m Additional time* | 6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 4h 57m Average total duration Fastest 1h 57m Onboard + 3h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $139 (€115) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $193 (€159).
A bus is $337 (€277) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $391 (€322).
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 5m.
Tickets start at around $54 (€44) compared to roughly $177 (€145) in fuel and tolls — a saving of about $123 (€101). The journey takes 10h 5m versus 7h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Infobus, Sindbad, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 12:50PM | Duration 12h05 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 12:50PM | Duration 11h45 | Departure days Everyday | Cheapest price $77 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 01:50PM | Duration 6h50 | Departure days Sun | Cheapest price $80 |
Operator Sindbad | Departure Time 07:35AM | Arrival Time 05:45PM | Duration 10h10 | Departure days Thu, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 08:50PM | Duration 12h35 | Departure days Everyday | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 03:10PM | Duration 6h50 | Departure days Tue | Cheapest price $61 |
Operator BlaBlaCar Bus | Departure Time 08:55AM | Arrival Time 08:45PM | Duration 11h50 | Departure days Wed, Fri, Sun | Cheapest price $61 |
Operator Alsa | Departure Time 08:55AM | Arrival Time 08:40PM | Duration 11h45 | Departure days Wed, Fri, Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 04:30PM | Duration 7h30 | Departure days Sun | Cheapest price $74 |
Operator Alsa | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Wed, Fri, Sun | Cheapest price $29 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 11:15PM | Duration 12h20 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 11:20AM | Arrival Time 11:15PM | Duration 11h55 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 04:20AM | Duration 14h17 | Departure days Mon, Tue, Thu, Sat | Cheapest price $80 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 04:20AM | Duration 12h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 04:20AM | Duration 12h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $86 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 11:50PM | Duration 6h50 | Departure days Fri | Cheapest price $54 |
Operator FlixBus | Departure Time 06:03PM | Arrival Time 04:20AM | Duration 10h17 | Departure days Fri, Sun | Cheapest price $81 |
Operator BlaBlaCar Bus | Departure Time 06:30PM | Arrival Time 05:10AM | Duration 10h40 | Departure days Everyday | Cheapest price $61 |
Operator FlixBus | Departure Time 07:05PM | Arrival Time 05:05AM | Duration 10h00 | Departure days Everyday | Cheapest price $75 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 05:05AM | Duration 9h35 | Departure days Everyday | Cheapest price $83 |
Operator BlaBlaCar | Departure Time 10:40PM | Arrival Time 05:40AM | Duration 7h00 | Departure days Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:30AM | Duration 11h45 | Departure days Everyday | Cheapest price $52 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:30AM | Duration 11h25 | Departure days Everyday | Cheapest price $55 |
The table below shows live departures for Frankfurt am Main to Lyon buses for today, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 8:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 12h35 | 8:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
54153 | 8:55 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h50 | 8:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Normal | 8:55 AM Frankfurt am Main, Mannheimer Straße (Hauptbahnhof) | 11h45 | 8:40 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
Normal | 9:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h10 | 8:40 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus · FlixBus | 10:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 12h20 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 11:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h55 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
51510 | 6:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 10h40 | 5:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 10h00 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h35 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 10:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h45 | 10:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h25 | 10:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Thursday, July 9 | |||||
FlixBus · FlixBus | 12:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 12h05 | 12:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h45 | 12:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Lyon run on average 12 times per day, taking around 10h 5m. Cheap bus tickets for this journey start at $29 (€24) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 9h 40m.
Distance 349 miles (563 km) |
Average bus duration 10h 5m |
Cheapest ticket price $29 (€24) |
Buses per day 12 |
Direct buses 5 |
Fastest bus 9h 40m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 35 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities, and decorative arts.
Archaeological museum and Roman theatres complex explaining ancient Lugdunum, the Roman city that became Lyon.
Striking science and society museum at the confluence of the Rhône and Saône, known for its architecture and immersive exhibitions.
Lyon's atmospheric old town, famous for Renaissance streets, traboules, and lively pedestrian lanes.
The central peninsula between the Rhône and Saône, packed with shopping streets, squares, and classic city architecture.
One of Europe's largest open squares, a key meeting point and base for exploring central Lyon.
Light dumplings traditionally made with pike and served with a rich Nantua crayfish sauce, a classic of Lyonnais cuisine.
A traditional Lyon salad with frisée, lardons, croutons, and a poached egg, widely served in local bouchons.
Pork sausage baked inside brioche, a beloved Lyon specialty that reflects the city’s charcuterie tradition.
Legendary fine-dining institution with deep Lyon culinary heritage and polished, high-end tasting menus.
Popular modern bouchon known for refined takes on Lyon classics and a warm, intimate atmosphere.
Well-known traditional bouchon serving classic Lyonnais dishes in a lively, rustic setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Small change or rounding up is appreciated; 5-10% only for exceptional service. Taxis are usually rounded up, and tips in bars or cafes are modest.
Official public transport app
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
Find answers to the most common questions about traveling from Frankfurt am Main to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Lyon buses use the Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan). Use this guide to compare Frankfurt am Main and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Here are some other resources that might have the information you need