- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$39
Average price
$93
Fastest journey
9 h 35 m
Average duration
10 h 9 m
Buses per day
17
Distance
563 km
The best way to find a cheap bus ticket from Frankfurt am Main to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Lyon will cost around $93 if you buy it on the day, but the cheapest tickets can be found for only $39.
Of the 17 buses that leave Frankfurt am Main for Lyon on Sun, Aug 23, 10 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Aug 23 the direct buses cover the 563 km distance in an average of 10 h 9 m but if you time it right, some buses will get you there in just 9 h 35 m .
On Sun, Aug 23 the slowest buses will take 10 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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51510Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $30. For those with little time consider booking a flight which can get you there in 1h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $30, and a flight costs an average of $171.
Distance: 349 miles (563 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$54 Average price Cheapest | $177 Average price | $319 Average price | $183 Average price (fuel + tolls) |
10h 43m Average total duration 10h 13m Onboard + 30m Additional time* | 6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 4h 54m Average total duration Fastest 1h 54m Onboard + 3h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $123 less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $177.
A bus is $265 less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $319.
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 13m.
Tickets start at around $54 compared to roughly $183 in fuel and tolls — a saving of about $129. The journey takes 10h 13m versus 7h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Alsa, Sindbad, Infobus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 12:00AM | Arrival Time 07:40AM | Duration 7h40 | Departure days Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 12:45AM | Arrival Time 12:50PM | Duration 12h05 | Departure days Everyday | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 12:50AM | Arrival Time 08:00AM | Duration 7h10 | Departure days Tue | Cheapest price $68 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 12:50PM | Duration 11h45 | Departure days Everyday | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 01:20PM | Duration 7h20 | Departure days Sat | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 01:50PM | Duration 6h50 | Departure days Tue | Cheapest price $46 |
Operator Sindbad | Departure Time 07:30AM | Arrival Time 05:45PM | Duration 10h15 | Departure days Thu, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 08:50PM | Duration 12h35 | Departure days Everyday | Cheapest price $52 |
Operator BlaBlaCar Bus | Departure Time 08:55AM | Arrival Time 08:45PM | Duration 11h50 | Departure days Wed, Fri, Sun | Cheapest price $56 |
Operator Alsa | Departure Time 08:55AM | Arrival Time 08:40PM | Duration 11h45 | Departure days Wed, Fri, Sun | Cheapest price $50 |
Operator Alsa | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Wed, Fri, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 11:15PM | Duration 12h20 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 11:20AM | Arrival Time 11:15PM | Duration 11h55 | Departure days Everyday | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 01:40PM | Arrival Time 09:10PM | Duration 7h30 | Departure days Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 04:20AM | Duration 14h17 | Departure days Wed, Thu, Sat | Cheapest price $63 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 04:20AM | Duration 12h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 04:20AM | Duration 12h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 06:03PM | Arrival Time 04:20AM | Duration 10h17 | Departure days Fri, Sun | Cheapest price $91 |
Operator BlaBlaCar Bus | Departure Time 06:30PM | Arrival Time 05:10AM | Duration 10h40 | Departure days Everyday | Cheapest price $56 |
Operator FlixBus | Departure Time 07:05PM | Arrival Time 05:05AM | Duration 10h00 | Departure days Everyday | Cheapest price $62 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 05:05AM | Duration 9h35 | Departure days Everyday | Cheapest price $58 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:30AM | Duration 11h45 | Departure days Everyday | Cheapest price $56 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:30AM | Duration 11h25 | Departure days Everyday | Cheapest price $58 |
The table below shows live departures for Frankfurt am Main to Lyon buses for today, Saturday, August 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h55 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus+ FlixTrain | 2:03 PM Frankfurt South station | 14h17 | 4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 3:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 12h50 | 4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 12h20 | 4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
51510 | 6:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 10h40 | 5:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 10h00 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 7:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h35 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 10:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h45 | 10:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h25 | 10:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Sunday, August 23 | |||||
FlixBus · FlixBus | 12:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h55 | 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h35 | 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
0 | 7:30 AM Frankfurt am Main | 10h15 | 5:45 PM Lyon | 0 transfersDirect | |
FlixBus | 8:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 12h35 | 8:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Normal | 8:55 AM Frankfurt am Main, Mannheimer Straße (Hauptbahnhof) | 11h45 | 8:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
54153 | 8:55 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h50 | 8:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Normal | 9:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h10 | 8:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 10:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 12h20 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Lyon run on average 12 times per day, taking around 10h 13m. Cheap bus tickets for this journey start at $30 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 10h 0m.
Distance 349 miles (563 km) |
Average bus duration 10h 13m |
Cheapest ticket price $30 |
Buses per day 12 |
Direct buses 5 |
Fastest bus 10h 0m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 35 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Frankfurt am Main to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Lyon buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Frankfurt am Main and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Frankfurt am Main, Hauptbahnhof is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Hauptbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets and cafes are inside the station.
Free Wi-Fi is available throughout the station. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Frankfurt am Main, Hauptbahnhof.
Available at Frankfurt am Main, Hauptbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Hauptbahnhof: The station is fully accessible to wheelchair users.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Here are some other resources that might have the information you need