Prague to Lyon bus with FlixBus

Fri, Dec 05
+ Add return
FlixBus
BlaBlaCar Bus
Alsa
Rede Expressos
Itabus
1,000+ travel companies
FlixBus
BlaBlaCar Bus
Alsa
Rede Expressos
Itabus
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Prague to Lyon

Showing times and prices for Dec 06

Cheapest price

$88

Average price

$100

Fastest journey

14 h 35 m

Average duration

15 h 59 m

Buses per day

13

Distance

860 km

Cheap tickets

The best way to find a cheap bus ticket from Prague to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Lyon will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $88.

Fast buses

Of the 13 buses that leave Prague for Lyon on Sat, Dec 06, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sat, Dec 06 the direct buses cover the 860 km distance in an average of 15 h 59 m but if you time it right, some buses will get you there in just 14 h 35 m .

On Sat, Dec 06 the slowest buses will take 17 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBusFlixBus
09:50PM14h35
Praha, Na Knížecí
12:25PMLyon, Perrache Bus Station
$881One-way
0 transfers
FlixBusFlixBus
09:25PM15h00
Praha, ÚAN Florenc
12:25PMLyon, Perrache Bus Station
$881One-way
0 transfers
FlixBusFlixBus
02:30PM17h45
Praha, Černý Most
08:15AMLyon, Perrache Bus Station
$911One-way
0 transfers
FlixBusFlixBus
03:10PM17h05
Praha, ÚAN Florenc
08:15AMLyon, Perrache Bus Station
$911One-way
0 transfers
FlixBusFlixBus
04:15PM16h45
Prague, Central Train Station
09:00AMLyon, Perrache Bus Station
$911One-way
0 transfers

Travel Information

Compare train, bus, and flight for Prague to Lyon

Omio recommends booking the flight as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €48. For those with little time consider booking a flight which can get you there in 2h 43m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of €48, and a train costs an average of €221.

Distance: 534 miles (860 km)

Compare bus with

Bus
Most popular
Flight
Train

€67

Average price

Cheapest

€181

Average price

€241

Average price

17h 42m

Average total duration

17h 12m

Onboard

+

30m

Additional time*

5h 43m

Average total duration

Fastest

2h 43m

Onboard

+

3h 0m

Additional time*

14h 30m

Average total duration

14h 0m

Onboard

+

30m

Additional time*

0.9 - 2.1kg

CO2 emissions

Lowest

2.6 - 5.2kg

CO2 emissions

-

CO2 emissions

FlixBus

Most popular bus company

Volotea

Most popular airline

Deutsche Bahn

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Prague to Lyon Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
03:50AM
Arrival Time
11:15PM
Duration
19h25
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$79
Operator
FlixBus
Departure Time
04:10AM
Arrival Time
11:15PM
Duration
19h05
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$79
Operator
FlixBus
Departure Time
05:50AM
Arrival Time
04:45AM
Duration
22h55
Departure days
Tue
Cheapest price
$89
Operator
FlixBus
Departure Time
06:40AM
Arrival Time
11:15PM
Duration
16h35
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$67
Operator
FlixBus
Departure Time
08:50AM
Arrival Time
04:45AM
Duration
19h55
Departure days
Tue, Wed
Cheapest price
$88
Operator
FlixBus
Departure Time
09:00AM
Arrival Time
04:35AM
Duration
19h35
Departure days
Mon, Fri
Cheapest price
$91
Operator
FlixBus
Departure Time
09:10AM
Arrival Time
04:45AM
Duration
19h35
Departure days
Everyday
Cheapest price
$88
Operator
FlixBus
Departure Time
09:40AM
Arrival Time
09:00AM
Duration
23h20
Departure days
Tue
Cheapest price
$85
Operator
FlixBus
Departure Time
09:55AM
Arrival Time
09:00AM
Duration
23h05
Departure days
Tue
Cheapest price
$84
Operator
FlixBus
Departure Time
11:15AM
Arrival Time
04:35AM
Duration
17h20
Departure days
Sat, Sun
Cheapest price
$120
Operator
FlixBus
Departure Time
12:55PM
Arrival Time
08:15AM
Duration
19h20
Departure days
Sun
Cheapest price
$107
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
08:15AM
Duration
19h10
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$99
Operator
BlaBlaCar Bus
Departure Time
01:35PM
Arrival Time
06:25AM
Duration
16h50
Departure days
Thu
Cheapest price
$78
Operator
FlixBus
Departure Time
02:30PM
Arrival Time
08:15AM
Duration
17h45
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$74
Operator
FlixBus
Departure Time
03:05PM
Arrival Time
08:15AM
Duration
17h10
Departure days
Wed, Thu, Sat
Cheapest price
$79
Operator
FlixBus
Departure Time
03:10PM
Arrival Time
08:15AM
Duration
17h05
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$74
Operator
FlixBus
Departure Time
04:00PM
Arrival Time
09:00AM
Duration
17h00
Departure days
Everyday
Cheapest price
$68
Operator
FlixBus
Departure Time
04:15PM
Arrival Time
09:00AM
Duration
16h45
Departure days
Everyday
Cheapest price
$68
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
02:45PM
Duration
21h00
Departure days
Tue
Cheapest price
$85
Operator
BlaBlaCar Bus
Departure Time
07:00PM
Arrival Time
06:45PM
Duration
23h45
Departure days
Sun
Cheapest price
$108
Operator
FlixBus
Departure Time
07:30PM
Arrival Time
02:45PM
Duration
19h15
Departure days
Tue
Cheapest price
$92
Operator
Infobus
Departure Time
09:00PM
Arrival Time
10:00AM
Duration
13h00
Departure days
Tue
Cheapest price
$223
Operator
FlixBus
Departure Time
09:25PM
Arrival Time
12:25PM
Duration
15h00
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$74
Operator
FlixBus
Departure Time
09:50PM
Arrival Time
12:25PM
Duration
14h35
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$74
Operator
FlixBus
Departure Time
09:55PM
Arrival Time
08:35PM
Duration
22h40
Departure days
Tue
Cheapest price
$85
Operator
FlixBus
Departure Time
10:15PM
Arrival Time
08:35PM
Duration
22h20
Departure days
Tue
Cheapest price
$84
Operator
Regiojet
Departure Time
11:00PM
Arrival Time
02:50PM
Duration
15h50
Departure days
Thu
Cheapest price
$81

Live departures

Prague to Lyon bus times

The table below shows live departures for Prague to Lyon buses for today, Friday, December 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:04 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus12:05 PM Prague, Central Train Station
19h10
7:15 AM Lyon, Perrache Bus Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus12:05 PM Praha, Zličín
19h10
7:15 AM Lyon, Perrache Bus Station1 transfer
meinfernbus_flixbusFlixBus1:30 PM Praha, Černý Most
17h45
7:15 AM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus2:10 PM Praha, ÚAN Florenc
17h05
7:15 AM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus3:00 PM Praha, ÚAN Florenc
17h00
8:00 AM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus3:15 PM Prague, Central Train Station
16h45
8:00 AM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus8:25 PM Praha, ÚAN Florenc
15h00
11:25 AM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus8:50 PM Praha, Na Knížecí
14h35
11:25 AM Lyon, Perrache Bus Station0 transfersDirect
Saturday, December 6
meinfernbus_flixbusFlixBus · FlixBus2:50 AM Prague, Central Train Station
19h25
10:15 PM Lyon, Perrache Bus Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus3:10 AM Praha, Na Knížecí
19h05
10:15 PM Lyon, Perrache Bus Station1 transfer
meinfernbus_flixbusFlixBus5:40 AM Praha, ÚAN Florenc
16h35
10:15 PM Lyon, Perrache Bus Station0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus8:10 AM Praha, Na Knížecí
19h35
3:45 AM Lyon, Perrache Bus Station1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Prague to Lyon by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Dec 05
Sat
Dec 06
Sun
Dec 07
Mon
Dec 08
Tue
Dec 09
Wed
Dec 10
Thu
Dec 11
Fri
Dec 12
Sat
Dec 13
Sun
Dec 14
Mon
Dec 15
Tue
Dec 16
Wed
Dec 17
Thu
Dec 18
Fri
Dec 19
Sat
Dec 20
Sun
Dec 21
Mon
Dec 22
Tue
Dec 23
Wed
Dec 24
Thu
Dec 25

Journey information

Overview: Bus from Prague to Lyon

CzechiaCzechia
FranceFrance
Icon of bus

Buses from Prague to Lyon run on average 12 times per day, taking around 17h 12m. Cheap bus tickets for this journey start at $60 (€48) but you can travel from only $57 (€46) by flight.

There are 5 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 14h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $57 (€46)
Distance
534 miles (860 km)
Average bus duration
17h 12m
Cheapest ticket price
$60 (€48)
Buses per day
12
Direct buses
5
Fastest bus
14h 35m
First bus
00:10
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $57 (€46)

Bus providers: FlixBus, BlaBlaCar Bus from Prague to LyonYou can travel by bus between Prague to Lyon with FlixBus, BlaBlaCar Bus for as low as $57 (€46). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 35m
Cheapest Price
$64 (€52)
FlixBus frequency
14 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
16h 45m
Cheapest Price
$60 (€48)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

FAQs: Bus from Prague to Lyon

Find answers to the most common questions about traveling from Prague to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Prague to Lyon can start from as little as $62 (€50) when you book in advance. The average bus ticket price for Prague to Lyon is $94 (€76); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Prague to Lyon bus time is 14 h 35 min   covering the 533 mile (860 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Prague to Lyon leaves at 2: 50AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Prague to Lyon leaves at 10: 50PM.
Yes, there are 4 direct buses a day from Prague to Lyon with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
For the journey from Prague to Lyon you can take a bus with FlixBus or BlaBlaCar Bus. Be sure to check out all possible bus providers that offer services to Lyon from Prague on Omio to compare what amenities they may have.
The cheapest month for a bus from Prague to Lyon is October.
You have options as you can travel between Prague and Lyon 3 different ways: bus, flight or train.
Yes, the following accessibility options are available when taking the bus from Prague to Lyon:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
Yes, there are bathrooms on board the bus from Prague to Lyon for bus providers FlixBus and BlaBlaCar Bus.
Some of the most interesting sights to explore in Lyon are:
  • Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
  • Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
  • Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
  • Musée des Confluences, a modern science and anthropology museum with innovative exhibits
  • Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
The best things to do in Lyon include:
  • Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
  • Take a river cruise on the Rhône and Saône for a unique view of the city
  • Explore the traboules, secret passageways in Vieux Lyon
  • Attend a performance at the Opéra de Lyon, known for its diverse program
  • Visit the Institut Lumière, dedicated to the history of cinema.
Yes, bikes are allowed on board the bus with bus providers FlixBus and BlaBlaCar Bus.
Whether you can cancel your bus ticket from Prague to Lyon depends on the bus providers:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.

To find the cheapest bus tickets for your trip from Prague to Lyon, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Prague to Lyon.
    Yes, the following luggage options are included when booking a bus ticket from Prague to Lyon:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • BlaBlaCar Bus
      • One carry-on bag up to 7kg and one checked bag up to 20kg.
    Yes, the following additional luggage options are available when booking a bus ticket from Prague to Lyon:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • BlaBlaCar Bus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Prague to Lyon. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Prague to Lyon with the following bus providers: FlixBus and BlaBlaCar Bus
    Yes, there are USB plugs on board the bus from Prague to Lyon with the following bus companies: FlixBus and BlaBlaCar Bus.
    Yes, there is Wifi on board the bus from Prague to Lyon with the following bus providers: FlixBus and BlaBlaCar Bus.

    popular bus stations

    Popular bus stations from Prague to Lyon

    Prague
    Lyon
    The major bus station for departures in Prague is Praha, Na Knížecí. Find all the information you need to know about services, amenities and connections at Praha, Na Knížecí for your trip from Prague to Lyon.
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    information
    ticketOfficeHours
    Distance to city center
    2 km
    carConnection
    Car connection
    Ostrovského
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Café Na Knížecí (in the station)
    • Bistro Praha (0.2 km)
    • Restaurace U Knížete (0.5 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, Na Knížecí
    • Bus: 137, 176, 191 Metro: B
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    Ticket OfficeTicket Office
    information
    ticketOfficeHours
    Ticket Office Hours
    • 00:00-23:59
    ticketOfficeHours
    Distance to city center
    1 km
    carConnection
    Car connection
    Wilsonova
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Czech Bistro (in the station)
    • Fast Food Express (in the station)
    • Bohemian Café (0.2 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, Hlavní Nádraží
    • Bus: 135, 175, 207 Metro: C Train: All major s
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    Ticket OfficeTicket Office
    information
    ticketOfficeHours
    Ticket Office Hours
    • 06:00-23:00
    ticketOfficeHours
    Distance to city center
    1 km
    carConnection
    Car connection
    Křižíkova
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Cafeteria Florenc (in the station)
    • Bistro Florenc (0.2 km)
    • Restaurace U Rozvařilů (0.5 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, ÚAN Florenc
    • Bus: 133, 135, 175, 207 Metro: B, C

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone