- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Oct 18
$90
Average ticket price on Oct 18
$136
Fastest journey on Oct 18
14 h 50 m
Average journey duration on Oct 18
16 h 7 m
Buses on Oct 18
19
Distance
860 km
The best way to find a cheap bus ticket from Prague to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Lyon will cost around $136 if you buy it on the day, but the cheapest tickets can be found for only $90.
On Sun, Oct 18, we found 19 buses from Prague to Lyon, including 7 direct services.
On Sun, Oct 18 the direct buses cover the 860 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Sun, Oct 18 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBusBuses from Prague to Lyon run on average 15 times per day, taking around 16h 52m. Cheap bus tickets for this journey start at $51 (€43) but you can travel from only $35 (€29) by flight.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 534 miles (860 km) distance in 13h 0m.
Distance 534 miles (860 km) |
Average bus duration 16h 52m |
Cheapest ticket price $51 (€43) |
Buses per day 15 |
Direct buses 6 |
Fastest bus 13h 0m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Tue |
Best time to book 56 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:30AM | Arrival Time 09:40PM | Duration 19h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $70 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 11:15PM | Duration 19h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 11:15PM | Duration 19h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 05:05AM | Duration 23h15 | Departure days Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 11:15PM | Duration 16h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 05:05AM | Duration 20h15 | Departure days Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 04:20AM | Duration 19h20 | Departure days Tue, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 05:05AM | Duration 19h55 | Departure days Wed, Thu | Cheapest price $75 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 04:20AM | Duration 19h00 | Departure days Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 04:20AM | Duration 18h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 08:15AM | Duration 21h20 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 04:20AM | Duration 17h05 | Departure days Mon, Fri, Sat | Cheapest price $96 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 12:50PM | Duration 24h05 | Departure days Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 10:30AM | Duration 21h40 | Departure days Mon, Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 08:15AM | Duration 19h20 | Departure days Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 08:15AM | Duration 19h10 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 08:15AM | Duration 17h45 | Departure days Everyday | Cheapest price $66 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 08:15AM | Duration 17h10 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $69 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 08:15AM | Duration 17h05 | Departure days Everyday | Cheapest price $66 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 09:05AM | Duration 17h05 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:05AM | Duration 16h50 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 02:45PM | Duration 21h00 | Departure days Mon, Tue | Cheapest price $69 |
Operator BlaBlaCar Bus | Departure Time 07:00PM | Arrival Time 04:25PM | Duration 21h25 | Departure days Thu, Sun | Cheapest price $124 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 03:20PM | Duration 19h55 | Departure days Mon, Tue, Wed, Thu | Cheapest price $73 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 02:45PM | Duration 19h15 | Departure days Mon, Tue | Cheapest price $81 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 03:20PM | Duration 19h00 | Departure days Wed, Thu, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 03:20PM | Duration 18h55 | Departure days Sun | Cheapest price $136 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 05:45PM | Duration 21h05 | Departure days Mon | Cheapest price $78 |
Operator AMI-Tour | Departure Time 09:00PM | Arrival Time 10:00AM | Duration 13h00 | Departure days Tue | Cheapest price $156 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 12:40PM | Duration 15h15 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 12:40PM | Duration 14h50 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 08:50PM | Duration 22h50 | Departure days Tue | Cheapest price $72 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 08:50PM | Duration 22h25 | Departure days Mon, Tue | Cheapest price $70 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 02:50PM | Duration 15h50 | Departure days Thu | Cheapest price $96 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 08:50PM | Duration 21h45 | Departure days Mon, Tue | Cheapest price $69 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 09:40PM | Duration 22h00 | Departure days Mon, Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 08:50PM | Duration 21h00 | Departure days Everyday | Cheapest price $69 |
The table below shows live departures for Prague to Lyon buses for today, Saturday, October 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:50 PM Prague, Central Train Station | 21h00 | 8:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Sunday, October 18 | |||||
FlixBus · FlixBus · FlixBus | 2:30 AM Prague, Central Train Station | 19h10 | 9:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
FlixBus · FlixBus | 3:25 AM Prague, Central Train Station | 19h50 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 3:40 AM Praha, Na Knížecí | 19h35 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 6:40 AM Praha, ÚAN Florenc | 16h35 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 9:00 AM Prague, Central Train Station | 19h20 | 4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 9:40 AM Praha, Na Knížecí | 18h40 | 4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 21h20 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 12:55 PM Praha, Zličín | 19h20 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:05 PM Prague, Central Train Station | 19h10 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 2:30 PM Praha, Černý Most | 17h45 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 3:10 PM Praha, ÚAN Florenc | 17h05 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 4:00 PM Praha, ÚAN Florenc | 17h05 | 9:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 4:15 PM Prague, Central Train Station | 16h50 | 9:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
30513 · 51708 | 7:00 PM Praha, ÚAN Florenc | 21h25 | 4:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Prague, Central Train Station | 19h00 | 3:20 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:25 PM Praha, Zličín | 18h55 | 3:20 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
FlixBus | 9:25 PM Praha, ÚAN Florenc | 15h15 | 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 9:50 PM Praha, Na Knížecí | 14h50 | 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Prague to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Prague to Lyon buses use the Praha, Hlavní Nádraží to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Prague and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
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