- Must visit
Royal Museums of Fine Arts of Belgium
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Cheapest price
$99
Average price
$211
Fastest journey
3 h 53 m
Average duration
3 h 56 m
Trains per day
42
Distance
569 km
The best way to find a cheap train ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $211 if you buy it on the day, but the cheapest tickets can be found for only $99.
Of the 42 trains that leave Lyon for Brussels on Thu, May 28, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct trains cover the 569 km distance in an average of 3 h 56 m but if you time it right, some trains will get you there in just 3 h 53 m .
On Thu, May 28 the slowest trains will take 3 h 59 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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9882
9868
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9882
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9864
9854Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $27. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $27, and a flight costs an average of $114.
Distance: 353 miles (569 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$163 Average price | $59 Average price Cheapest | $312 Average price | $197 Average price (fuel + tolls) |
5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Brussels:
A bus is $103 (€84) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $163 (€131).
A bus is $252 (€204) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $312 (€251).
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
The journey is about 2h 41m faster (4h 47m by train vs 7h 28m by car) and roughly $35 (€28) cheaper once you factor in fuel and tolls ($163 (€131) vs $197 (€159)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI, TGV.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Lyon to Brussels trains for today, Wednesday, May 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6612+ 9341 | 9:50 AM Gare de Lyon-Perrache | 4h27 | 2:17 PM Brussels-Midi | 1 transfer | |
6612+ 9341 | 10:04 AM Lyon Part Dieu | 4h13 | 2:17 PM Brussels-Midi | 1 transfer | |
6908+ 9351 | 10:54 AM Lyon Saint-Exupéry TGV | 4h54 | 3:48 PM Brussels-Midi | 1 transfer | |
6908+ 9451 | 10:54 AM Lyon Saint-Exupéry TGV | 4h54 | 3:48 PM Brussels-Midi | 1 transfer | |
6616+ 9351 | 11:16 AM Gare de Lyon-Perrache | 4h32 | 3:48 PM Brussels-Midi | 1 transfer | |
6616+ 9451 | 11:16 AM Gare de Lyon-Perrache | 4h32 | 3:48 PM Brussels-Midi | 1 transfer | |
6616+ 9351 | 11:34 AM Lyon Part Dieu | 4h14 | 3:48 PM Brussels-Midi | 1 transfer | |
6616+ 9451 | 11:34 AM Lyon Part Dieu | 4h14 | 3:48 PM Brussels-Midi | 1 transfer | |
6618+ 9459 | 12:49 PM Gare de Lyon-Perrache | 4h29 | 5:18 PM Brussels-Midi | 1 transfer | |
6618+ 9359 | 12:49 PM Gare de Lyon-Perrache | 4h29 | 5:18 PM Brussels-Midi | 1 transfer | |
6694+ 9459 | 1:04 PM Lyon Part Dieu | 4h14 | 5:18 PM Brussels-Midi | 1 transfer | |
6694+ 9359 | 1:04 PM Lyon Part Dieu | 4h14 | 5:18 PM Brussels-Midi | 1 transfer | |
6618+ 9359 | 1:04 PM Lyon Part Dieu | 4h14 | 5:18 PM Brussels-Midi | 1 transfer | |
6618+ 9459 | 1:04 PM Lyon Part Dieu | 4h14 | 5:18 PM Brussels-Midi | 1 transfer | |
6620+ 9369 | 1:50 PM Gare de Lyon-Perrache | 4h57 | 6:47 PM Brussels-Midi | 1 transfer | |
6910+ 9369 | 1:54 PM Lyon Saint-Exupéry TGV | 4h53 | 6:47 PM Brussels-Midi | 1 transfer | |
6620+ 9369 | 2:04 PM Lyon Part Dieu | 4h43 | 6:47 PM Brussels-Midi | 1 transfer | |
6624+ 9477 | 3:50 PM Gare de Lyon-Perrache | 4h32 | 8:22 PM Brussels-Midi | 1 transfer | |
6624+ 9377 | 3:50 PM Gare de Lyon-Perrache | 4h32 | 8:22 PM Brussels-Midi | 1 transfer | |
6920+ 9377 | 3:54 PM Lyon Saint-Exupéry TGV | 4h28 | 8:22 PM Brussels-Midi | 1 transfer | |
6920+ 9477 | 3:54 PM Lyon Saint-Exupéry TGV | 4h28 | 8:22 PM Brussels-Midi | 1 transfer | |
6624+ 9377 | 4:04 PM Lyon Part Dieu | 4h18 | 8:22 PM Brussels-Midi | 1 transfer | |
6624+ 9477 | 4:04 PM Lyon Part Dieu | 4h18 | 8:22 PM Brussels-Midi | 1 transfer | |
6626+ 9387 | 4:50 PM Gare de Lyon-Perrache | 4h54 | 9:44 PM Brussels-Midi | 1 transfer | |
9864 | 5:00 PM Lyon Part Dieu | 3h56 | 8:56 PM Brussels-Midi | 0 transfersDirect | |
9868 | 5:00 PM Lyon Part Dieu | 3h56 | 8:56 PM Brussels-Midi | 0 transfersDirect | |
6696+ 9387 | 5:38 PM Lyon Part Dieu | 4h06 | 9:44 PM Brussels-Midi | 1 transfer | |
6628+ 9393 | 5:50 PM Gare de Lyon-Perrache | 4h57 | 10:47 PM Brussels-Midi | 1 transfer | |
6922+ 9393 | 5:54 PM Lyon Saint-Exupéry TGV | 4h53 | 10:47 PM Brussels-Midi | 1 transfer | |
6628+ 9393 | 6:04 PM Lyon Part Dieu | 4h43 | 10:47 PM Brussels-Midi | 1 transfer | |
9882 | 7:01 PM Lyon Part Dieu | 3h55 | 10:56 PM Brussels-Midi | 0 transfersDirect | |
| Thursday, May 28 | |||||
9852 | 5:50 AM Lyon Part Dieu | 3h53 | 9:43 AM Brussels-Midi | 0 transfersDirect | |
6642+ 9321 | 6:24 AM Gare de Lyon-Perrache | 4h25 | 10:49 AM Brussels-Midi | 1 transfer | |
6644+ 9423 | 6:38 AM Gare de Lyon-Perrache | 4h39 | 11:17 AM Brussels-Midi | 1 transfer | |
6642+ 9321 | 6:38 AM Lyon Part Dieu | 4h11 | 10:49 AM Brussels-Midi | 1 transfer | |
6902+ 9423 | 6:54 AM Lyon Saint-Exupéry TGV | 4h23 | 11:17 AM Brussels-Midi | 1 transfer | |
6690+ 9423 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
6604+ 9423 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
6608+ 9329 | 7:50 AM Gare de Lyon-Perrache | 4h27 | 12:17 PM Brussels-Midi | 1 transfer | |
6608+ 9429 | 7:50 AM Gare de Lyon-Perrache | 4h27 | 12:17 PM Brussels-Midi | 1 transfer | |
6906+ 9329 | 7:59 AM Lyon Saint-Exupéry TGV | 4h18 | 12:17 PM Brussels-Midi | 1 transfer | |
6906+ 9429 | 7:59 AM Lyon Saint-Exupéry TGV | 4h18 | 12:17 PM Brussels-Midi | 1 transfer | |
6608+ 9429 | 8:04 AM Lyon Part Dieu | 4h13 | 12:17 PM Brussels-Midi | 1 transfer | |
6608+ 9329 | 8:04 AM Lyon Part Dieu | 4h13 | 12:17 PM Brussels-Midi | 1 transfer | |
9854 | 8:27 AM Lyon Part Dieu | 3h59 | 12:26 PM Brussels-Midi | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Lyon to Brussels run on average 4 times per day, taking around 4h 47m. Cheap train tickets for this journey start at $93 (€75) but you can travel from only $27 (€22) by bus.
There are 4 trains per day. The earliest train runs at 00:15, the last at 19:16. The fastest train covers the 353 miles (569 km) distance in 3h 53m.
Distance 353 miles (569 km) |
Average train duration 4h 47m |
Cheapest ticket price $93 (€75) |
Trains per day 4 |
Direct trains 4 |
Fastest train 3h 53m |
First train 12:15 AM |
Last train 7:16 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 56 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Dedicated to René Magritte, this museum holds the world's largest collection of his works. It is a standout stop for surrealism lovers and one of Brussels' most famous museums.
A contemporary art museum known for street art, digital culture, and youth-oriented exhibitions. It became especially popular with younger visitors and on social media.
A landscaped cultural hill linking the upper and lower city, known for its formal gardens and classic skyline view. It is one of Brussels' best walking and photography spots.
A beautiful 19th-century covered arcade with elegant glass roofing and historic atmosphere. It is one of the city's most photogenic and fashionable passages.
A grand urban park laid out around monumental buildings and the Cinquantenaire Arch. Ideal for a walk, photos, and combining with nearby museums.
Brussels’ classic pairing of mussels steamed with white wine, celery, and herbs, served with crisp fries. It is one of the city’s most iconic and widely loved meals.
A traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. It is a staple of local brasserie cuisine.
A comforting Brussels side dish of mashed potatoes mixed with seasonal vegetables such as carrots, leeks, or spinach, often served with sausage or meat.
Well-regarded Belgian restaurant serving regional classics, strong beer pairings, and seasonal ingredients in a cozy, old-Brussels dining room.
One of Brussels’ landmark fine-dining restaurants, celebrated for refined Belgian-influenced cuisine, polished service, and an elegant Art Nouveau setting.
Popular traditional restaurant near Sainte-Catherine known for generous Belgian comfort food, beer-based stews, and an unfussy, bustling atmosphere.
Moderate by Western European standards. Beer, waffles, and transit are reasonable; hotels and central dining cost more.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Round up taxi fares.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Lyon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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