1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Lyon to Brussels
Showing times and prices for Feb 26
Cheapest price
$138
Average price
$220
Fastest journey
3 h 59 m
Average duration
4 h 8 m
Trains per day
43
Distance
569 km
Cheap tickets
The best way to find a cheap train ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $220 if you buy it on the day, but the cheapest tickets can be found for only $138.
Fast trains
Of the 43 trains that leave Lyon for Brussels on Thu, Feb 26, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 26 the direct trains cover the 569 km distance in an average of 4 h 8 m but if you time it right, some trains will get you there in just 3 h 59 m .
On Thu, Feb 26 the slowest trains will take 4 h 13 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
985408:27AM3h59
Lyon Part Dieu12:26PMBrussels-Midi
$1381One-way
0 transfers
6620+
946902:04PM4h43
Lyon Part Dieu06:47PMBrussels-Midi
$1941One-way
1 transfer
6620+946901:50PM4h57
Gare de Lyon-Perrache06:47PMBrussels-Midi
$1941One-way
1 transfer
6628+939305:50PM4h57
Gare de Lyon-Perrache10:47PMBrussels-Midi
$1961One-way
1 transfer
6628+939306:04PM4h43
Lyon Part Dieu10:47PMBrussels-Midi
$1961One-way
1 transfer
985408:27AM3h59
Lyon Part Dieu12:26PMBrussels-Midi
$1381One-way
0 transfers
6696+938705:38PM4h06
Lyon Part Dieu09:44PMBrussels-Midi
$3191One-way
1 transfer
6902+942307:07AM4h10
Lyon Saint-Exupéry TGV11:17AMBrussels-Midi
$2781One-way
1 transfer
6642+932106:38AM4h11
Lyon Part Dieu10:49AMBrussels-Midi
$2041One-way
1 transfer
6608+942908:04AM4h13
Lyon Part Dieu12:17PMBrussels-Midi
$2061One-way
1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $121.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$130 Average price | $52 Average price Cheapest | $287 Average price |
6h 8m Average total duration 5h 38m Onboard + 30m Additional time* | 8h 27m Average total duration 7h 57m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Brussels train times
The table below shows live departures for Lyon to Brussels trains for tomorrow, Thursday, February 26. You can also manually refresh the results below to see updated train journeys.
Last updated at 10:06 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6642+9321 | 5:24 AM Gare de Lyon-Perrache | 4h25 | 9:49 AM Brussels-Midi | 1 transfer | |
| 6642+9321 | 5:38 AM Lyon Part Dieu | 4h11 | 9:49 AM Brussels-Midi | 1 transfer | |
| 6644+9423 | 5:38 AM Gare de Lyon-Perrache | 4h39 | 10:17 AM Brussels-Midi | 1 transfer | |
| 6690+9423 | 6:04 AM Lyon Part Dieu | 4h13 | 10:17 AM Brussels-Midi | 1 transfer | |
| 6604+9423 | 6:04 AM Lyon Part Dieu | 4h13 | 10:17 AM Brussels-Midi | 1 transfer | |
| 6902+9423 | 6:07 AM Lyon Saint-Exupéry TGV | 4h10 | 10:17 AM Brussels-Midi | 1 transfer | |
| 6608+9429 | 6:50 AM Gare de Lyon-Perrache | 4h27 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6608+9329 | 6:50 AM Gare de Lyon-Perrache | 4h27 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6906+9429 | 6:54 AM Lyon Saint-Exupéry TGV | 4h23 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6906+9329 | 6:54 AM Lyon Saint-Exupéry TGV | 4h23 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6608+9429 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6608+9329 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
| 9854 | On time 7:27 AM Lyon Part Dieu | 3h59 | 11:26 AM Brussels-Midi | 0 transfersDirect | |
| 6908+9351 | 9:53 AM Lyon Saint-Exupéry TGV | 4h55 | 2:48 PM Brussels-Midi | 1 transfer | |
| 6908+9451 | 9:53 AM Lyon Saint-Exupéry TGV | 4h55 | 2:48 PM Brussels-Midi | 1 transfer | |
| 9862 | On time 10:00 AM Lyon Part Dieu | 4h26 | 2:26 PM Brussels-Midi | 0 transfersDirect | |
| 6616+9351 | 10:16 AM Gare de Lyon-Perrache | 4h32 | 2:48 PM Brussels-Midi | 1 transfer | |
| 6616+9451 | 10:16 AM Gare de Lyon-Perrache | 4h32 | 2:48 PM Brussels-Midi | 1 transfer | |
| 6616+9351 | 10:34 AM Lyon Part Dieu | 4h14 | 2:48 PM Brussels-Midi | 1 transfer | |
| 6616+9451 | 10:34 AM Lyon Part Dieu | 4h14 | 2:48 PM Brussels-Midi | 1 transfer | |
| 6618+9459 | 11:49 AM Gare de Lyon-Perrache | 4h28 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6618+9359 | 11:49 AM Gare de Lyon-Perrache | 4h28 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6694+9359 | 12:04 PM Lyon Part Dieu | 4h13 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6618+9459 | 12:04 PM Lyon Part Dieu | 4h13 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6618+9359 | 12:04 PM Lyon Part Dieu | 4h13 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6694+9459 | 12:04 PM Lyon Part Dieu | 4h13 | 4:17 PM Brussels-Midi | 1 transfer | |
| 6910+9369 | 12:50 PM Lyon Saint-Exupéry TGV | 4h57 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6620+9469 | 12:50 PM Gare de Lyon-Perrache | 4h57 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6620+9369 | 12:50 PM Gare de Lyon-Perrache | 4h57 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6910+9469 | 12:50 PM Lyon Saint-Exupéry TGV | 4h57 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6620+9469 | 1:04 PM Lyon Part Dieu | 4h43 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6620+9369 | 1:04 PM Lyon Part Dieu | 4h43 | 5:47 PM Brussels-Midi | 1 transfer | |
| 6622+9371 | 1:50 PM Gare de Lyon-Perrache | 4h27 | 6:17 PM Brussels-Midi | 1 transfer | |
| 6622+9471 | 1:50 PM Gare de Lyon-Perrache | 4h27 | 6:17 PM Brussels-Midi | 1 transfer | |
| 6622+9371 | 2:04 PM Lyon Part Dieu | 4h13 | 6:17 PM Brussels-Midi | 1 transfer | |
| 6622+9471 | 2:04 PM Lyon Part Dieu | 4h13 | 6:17 PM Brussels-Midi | 1 transfer | |
| 6624+9381 | 2:50 PM Gare de Lyon-Perrache | 4h57 | 7:47 PM Brussels-Midi | 1 transfer | |
| 6624+9381 | 3:04 PM Lyon Part Dieu | 4h43 | 7:47 PM Brussels-Midi | 1 transfer | |
| 6626+9387 | 3:50 PM Gare de Lyon-Perrache | 4h54 | 8:44 PM Brussels-Midi | 1 transfer | |
| 6696+9387 | 4:38 PM Lyon Part Dieu | 4h06 | 8:44 PM Brussels-Midi | 1 transfer | |
| 6628+9393 | 4:50 PM Gare de Lyon-Perrache | 4h57 | 9:47 PM Brussels-Midi | 1 transfer | |
| 6922+9389 | 4:54 PM Lyon Saint-Exupéry TGV | 4h23 | 9:17 PM Brussels-Midi | 1 transfer | |
| 6628+9393 | 5:04 PM Lyon Part Dieu | 4h43 | 9:47 PM Brussels-Midi | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Thu
Feb 26
Feb 26
Fri
Feb 27
Feb 27
Sat
Feb 28
Feb 28
Sun
Mar 01
Mar 01
Mon
Mar 02
Mar 02
Tue
Mar 03
Mar 03
Wed
Mar 04
Mar 04
Thu
Mar 05
Mar 05
Fri
Mar 06
Mar 06
Sat
Mar 07
Mar 07
Sun
Mar 08
Mar 08
Mon
Mar 09
Mar 09
Tue
Mar 10
Mar 10
Wed
Mar 11
Mar 11
Thu
Mar 12
Mar 12
Fri
Mar 13
Mar 13
Sat
Mar 14
Mar 14
Sun
Mar 15
Mar 15
Mon
Mar 16
Mar 16
Tue
Mar 17
Mar 17
Wed
Mar 18
Mar 18
How far in advance should I book train tickets from Lyon to Brussels?
The best time to book your train from Lyon to Brussels is 77 days before departure. See how prices for trains change on the Lyon to Brussels route.
Prices are for one-way tickets for one passenger from Lyon to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Lyon to Brussels.
Trains
from $112Buses
from $42Flights
from $181Journey information
Overview: Train from Lyon to Brussels
France
Belgium
Trains from Lyon to Brussels run on average 5 times per day, taking around 5h 38m. Cheap train tickets for this journey start at $58 (€46) but you can travel from only $24 (€19) by bus.
There are 4 trains per day. The earliest train runs at 00:15, the last at 19:16. The fastest train covers the 353 miles (569 km) distance in 3h 43m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $24 (€19)
Distance 353 miles (569 km) |
Average train duration 5h 38m |
Cheapest ticket price $58 (€46) |
Trains per day 5 |
Direct trains 4 |
Fastest train 3h 43m |
First train 00:15 |
Last train 19:16 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $24 (€19)
Train companies: TGV, TGV INOUI from Lyon to Brussels trainsTGV, TGV INOUI trains will get you between Lyon and Brussels from $24 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
About
TGV is a high-speed train company based in France. It operates a fleet of modern trains that can reach speeds of up to 320 km/h. The TGV offers a variety of train types, including the TGV Duplex, TGV Lyria, TGV InOui, and TGV OuiGo. Each train type provides different amenities, such as Wi-Fi, power outlets, and comfortable seating. Ticket options include Standard, Flexi, and Prem’s. Onboard facilities feature a bar, restaurant, and luggage storage. Popular TGV routes include Paris to Lyon, Paris to Marseille, and Paris to Lille.
Luggage & cancellation policy
Average Duration
3h 41m
Cheapest Price
$87 (€69)
TGV frequency
6 a day
Luggage included
2 pieces of hand luggage and 1 suitcase included in ticket price
Luggage storage
Dedicated luggage areas at end of carriages and overhead racks
Cancellation Policy
According to fare conditions and ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals and bar service, at-seat dining in first class
Seat reservation
Included in first class, optional fee in second class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket, guide dogs travel free
Quiet zone
TGV INOUI
About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Average Duration
3h 43m
Cheapest Price
$58 (€46)
TGV INOUI frequency
5 a day
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone
FAQs: Trains from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Train ticket prices from Lyon to Brussels can vary. The cheapest ticket starts at $58 (€46), while the average price is around $136 (€108).
The train from Lyon to Brussels takes 3h 43m and runs 4 per day.
The distance by train from Lyon to Brussels is 353 miles (569 km).
The first train from Lyon to Brussels leaves at 12:15 AM.
The last train from Lyon to Brussels leaves at 7:16 PM.
Yes, there is a high-speed train from Lyon to Brussels.
Yes, there is a direct train from Lyon to Brussels. This service operates 4 times per day, provided by TGV, TGV INOUI.
Unfortunately, there is no night train available from Lyon to Brussels.
The train station in Lyon that goes to Brussels is Lyon Part Dieu, which connects to Brussels-Midi.
The cheapest way to get from Lyon to Brussels is by bus, with a cost of around $24 (€19).
The train journey from Lyon to Brussels offers scenic views, particularly as it passes through the picturesque landscapes of the French countryside and the rolling hills of southern Belgium. Passengers can enjoy views of charming villages, lush fields, and historical architecture along the route.
A day trip from Lyon to Brussels is not feasible as the journey takes 3h 43m each way. The distance is 353 miles (569 km), with 5 trains available per day.
In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.
For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.
Yes, you can take the train from Lyon to Brussels.
popular train stations
Popular train stations from Lyon to Brussels
Lyon
Brussels
The major train station for departures in Lyon is Lyon Part Dieu. Find all the information you need to know about services, amenities and connections at Lyon Part Dieu for your trip from Lyon to Brussels.
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Distance to city center
1 kmWifi
- Free unlimited WiFi.
Lockers
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
Dining
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
Accessibility
- Complimentary personalized care is available.
Hotel
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
Ticket Office
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Information Desk
- Located in the station's main hall.
Public transit options for Lyon Part Dieu
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
Amenities at train station
WifiParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Fri: 10:00 - 18:00
Distance to city center
1 kmWifi
- Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION."
Dining
- PAUL
Accessibility
- Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
Hotel
- Mercure Lyon Centre Chateau Perrache
- Hotel De Normandie
- InterContinental Lyon-Hotel Dieu
Ticket Office
- Mon - Fri: 10:00 - 18:00
Information Desk
- Information services are available at the ticket office, located in Hall Level 2.
Public transit options for Lyon-Perrache
- Metro lines: A, B, C, D
- Bus lines: 8, 31, 46, 49, 55, 60, 63, S1, C19, C21, C22
- Tram lines: 1, 2
- Train lines: TGV, TGV INOUI, OUIGO, TER Auvergne-Rhône-Alpes, Intercités
The major train station for arrivals in Brussels is Bruxelles-Midi. Find all the information you need to know about services, amenities and connections at Bruxelles-Midi for your journey to Brussels from Lyon.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:45 - 21:30
Wifi
- Wi-Fi is available for a fee.
Lockers
- Baggage storage facility is located across from the Thalys business lounge.
Dining
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
Accessibility
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
Information Desk
- Located in the main concourse and next to the international platforms.
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
Most popular trains to and from Brussels and Lyon
Most popular train connections to Brussels
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
