- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Sep 01
$33
Average ticket price on Sep 01
$39
Fastest journey on Sep 01
10 h 10 m
Average journey duration on Sep 01
10 h 49 m
Buses on Sep 01
7
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around $39 if you buy it on the day, but the cheapest tickets can be found for only $33.
On Tue, Sep 01, we found 7 buses from Brussels to Lyon, including 1 direct services.
On Tue, Sep 01 the direct buses cover the 569 km distance in an average of 10 h 49 m but if you time it right, some buses will get you there in just 10 h 10 m .
On Tue, Sep 01 the slowest buses will take 12 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
50338 · 4787
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
50338 · 5133
51112 · 5807
50338 · 5133
50338 · 4787
FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $48 For those with little time, consider booking a flight, which has an average total journey time of 4h 24m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $48, while a flight costs an average of $285.
Distance: 353 miles (569 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$48 Average price Cheapest | $145 Average price | $285 Average price | $198 Average price (fuel + tolls) |
8h 33m Average total duration 8h 3m Onboard + 30m Additional time* | 4h 59m Average total duration 4h 29m Onboard + 30m Additional time* | 4h 24m Average total duration Fastest 2h 24m Onboard + 2h 0m Additional time* | 6h 56m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Lyon:
A bus is $97 (€78) less than a train for this route with tickets for a train from Brussels to Lyon costing on average $145 (€118).
A bus is $237 (€192) less than a flight for this route with tickets for a flight from Brussels to Lyon costing on average $285 (€231).
Other travel options to Lyon take longer:
Train takes on average 4h 29m.
Bus takes on average 8h 3m.
Tickets start at around $48 (€39) compared to roughly $198 (€160) in fuel and tolls — a saving of about $149 (€121). The journey takes 8h 3m versus 6h 56m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 12:35PM | Duration 11h05 | Departure days Sat, Sun | Cheapest price $34 |
Operator BlaBlaCar Bus | Departure Time 03:11AM | Arrival Time 02:40PM | Duration 11h29 | Departure days Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 04:15AM | Arrival Time 03:25PM | Duration 11h10 | Departure days Fri, Sat, Sun | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 02:20PM | Duration 8h20 | Departure days Sat | Cheapest price $71 |
Operator BlaBlaCar Bus | Departure Time 06:40AM | Arrival Time 06:50PM | Duration 12h10 | Departure days Thu | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:40PM | Duration 7h40 | Departure days Wed | Cheapest price $79 |
Operator BlaBlaCar Bus | Departure Time 07:20AM | Arrival Time 06:50PM | Duration 11h30 | Departure days Mon, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 03:50PM | Duration 7h50 | Departure days Mon, Tue | Cheapest price $55 |
Operator BlaBlaCar Bus | Departure Time 08:05AM | Arrival Time 07:10PM | Duration 11h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 05:00PM | Duration 8h00 | Departure days Fri | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 05:10PM | Duration 7h40 | Departure days Mon | Cheapest price $84 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 05:50PM | Duration 7h50 | Departure days Fri | Cheapest price $82 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 11:50PM | Duration 13h45 | Departure days Tue, Thu, Sat | Cheapest price $30 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 11:50PM | Duration 12h45 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $30 |
Operator BlaBlaCar Bus | Departure Time 11:30AM | Arrival Time 11:50PM | Duration 12h20 | Departure days Mon | Cheapest price $62 |
Operator FlixBus | Departure Time 11:35AM | Arrival Time 11:50PM | Duration 12h15 | Departure days Sat, Sun | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 09:00PM | Duration 8h00 | Departure days Mon | Cheapest price $63 |
Operator BlaBlaCar Bus | Departure Time 01:30PM | Arrival Time 12:20AM | Duration 10h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 03:10AM | Duration 13h30 | Departure days Mon, Tue | Cheapest price $35 |
Operator FlixBus | Departure Time 02:05PM | Arrival Time 04:50AM | Duration 14h45 | Departure days Mon | Cheapest price $70 |
Operator BlaBlaCar Bus | Departure Time 02:20PM | Arrival Time 12:50AM | Duration 10h30 | Departure days Mon, Thu, Fri, Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 02:00AM | Duration 10h50 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $31 |
Operator BlaBlaCar Bus | Departure Time 03:50PM | Arrival Time 03:30AM | Duration 11h40 | Departure days Wed | Cheapest price $27 |
Operator BlaBlaCar Bus | Departure Time 04:35PM | Arrival Time 03:30AM | Duration 10h55 | Departure days Thu | Cheapest price $27 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 05:20AM | Duration 12h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $30 |
Operator BlaBlaCar Bus | Departure Time 04:55PM | Arrival Time 03:30AM | Duration 10h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 12:30AM | Duration 7h30 | Departure days Wed | Cheapest price $66 |
Operator BlaBlaCar Bus | Departure Time 05:55PM | Arrival Time 04:05AM | Duration 10h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar Bus | Departure Time 06:20PM | Arrival Time 04:30AM | Duration 10h10 | Departure days Mon, Tue | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 06:50PM | Arrival Time 03:20AM | Duration 8h30 | Departure days Tue, Sat | Cheapest price $71 |
Operator BlaBlaCar Bus | Departure Time 07:05PM | Arrival Time 05:20AM | Duration 10h15 | Departure days Everyday | Cheapest price $27 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 06:50AM | Duration 10h35 | Departure days Everyday | Cheapest price $51 |
Operator BlaBlaCar Bus | Departure Time 10:15PM | Arrival Time 09:15AM | Duration 11h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $56 |
The table below shows live departures for Brussels to Lyon buses for today, Monday, August 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:05 AM Brussels, Brussels South (Gare du Midi) | 12h45 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50324 · 94763 | 11:30 AM Brussels, Brussels South (Gare du Midi) | 12h20 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1646 · 50107 | 1:30 PM Brussels, Brussels South (Gare du Midi) | 10h50 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:40 PM Brussels, Brussels South (Gare du Midi) | 13h30 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:05 PM Brussels, Brussels South (Gare du Midi) | 14h45 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
50332 · 3357 | 2:20 PM Brussels, Brussels South (Gare du Midi) | 10h30 | 12:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Brussels, Brussels South (Gare du Midi) | 12h40 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50336 · 83133 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 11h10 | 4:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1408 · 5807 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 4:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
51112 · 5133 | 6:20 PM Brussels, Brussels South (Gare du Midi) | 11h00 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50338 · 4787 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50338 · 50883 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:15 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
51094 | 10:15 PM Brussels, Brussels South (Gare du Midi) | 11h00 | 9:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brussels to Lyon run on average 15 times per day, taking around 8h 3m. Cheap bus tickets for this journey start at $27 (€22) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 353 miles (569 km) distance in 10h 10m.
Distance 353 miles (569 km) |
Average bus duration 8h 3m |
Cheapest ticket price $27 (€22) |
Buses per day 15 |
Direct buses 3 |
Fastest bus 10h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sun |
Best time to book 77 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Brussels to Lyon buses use the Brussels, Brussels South (Gare du Midi) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Brussels and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Here are some other resources that might have the information you need