The cheapest and fastest buses from Brussels to Lyon
Cheapest price
$37
Average price
$56
Fastest journey
7 h 40 m
Average duration
9 h 50 m
Buses per day
13
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $37.
Of the 13 buses that leave Brussels for Lyon on Thu, Dec 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Dec 04 the direct buses cover the 569 km distance in an average of 9 h 50 m but if you time it right, some buses will get you there in just 7 h 40 m .
On Thu, Dec 04 the slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1646 · 50107
50326 · 5131
FlixBus · FlixBus
FlixBus · FlixBus
1408 · 5807
50338 · 5133
50338 · 4787
FlixBus
1408 · 5807Travel Information
Compare train, bus, and flight for Brussels to Lyon
Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €134.
Distance: 353 miles (569 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€43 Average price Cheapest | €126 Average price | €315 Average price |
10h 2m Average total duration 9h 32m Onboard + 30m Additional time* | 4h 13m Average total duration 3h 43m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Brussels to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 01:00AM | Arrival Time 08:40AM | Duration 7h40 | Departure days Thu | Cheapest price $66 |
Operator FlixBus | Departure Time 01:30AM | Arrival Time 02:45PM | Duration 13h15 | Departure days Everyday | Cheapest price $40 |
Operator BlaBlaCar Bus | Departure Time 03:11AM | Arrival Time 02:35PM | Duration 11h24 | Departure days Mon, Fri, Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 04:15AM | Arrival Time 03:20PM | Duration 11h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $41 |
Operator BlaBlaCar Bus | Departure Time 06:40AM | Arrival Time 06:45PM | Duration 12h05 | Departure days Thu | Cheapest price $38 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:40PM | Duration 7h40 | Departure days Sat | Cheapest price $76 |
Operator BlaBlaCar Bus | Departure Time 07:20AM | Arrival Time 06:45PM | Duration 11h25 | Departure days Mon, Fri, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 08:45PM | Duration 13h05 | Departure days Fri | Cheapest price $81 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 03:50PM | Duration 7h50 | Departure days Mon | Cheapest price $69 |
Operator FlixBus | Departure Time 09:35AM | Arrival Time 08:45PM | Duration 11h10 | Departure days Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 11:20PM | Duration 13h15 | Departure days Tue, Thu, Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:20PM | Duration 12h40 | Departure days Thu | Cheapest price $68 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 06:50PM | Duration 7h50 | Departure days Wed | Cheapest price $76 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 11:20PM | Duration 11h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 08:20PM | Duration 8h20 | Departure days Wed | Cheapest price $76 |
Operator BlaBlaCar Bus | Departure Time 01:30PM | Arrival Time 12:15AM | Duration 10h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $31 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 01:10AM | Duration 11h30 | Departure days Tue, Wed, Thu | Cheapest price $41 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 01:10AM | Duration 10h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 03:20AM | Duration 12h10 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 12:00AM | Duration 8h30 | Departure days Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 03:20AM | Duration 10h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 12:50AM | Duration 7h50 | Departure days Fri | Cheapest price $76 |
Operator BlaBlaCar Bus | Departure Time 05:55PM | Arrival Time 04:30AM | Duration 10h35 | Departure days Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator BlaBlaCar Bus | Departure Time 07:05PM | Arrival Time 05:15AM | Duration 10h10 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 06:45AM | Duration 10h30 | Departure days Everyday | Cheapest price $50 |
Live departures
Brussels to Lyon bus times
The table below shows live departures for Brussels to Lyon buses for today, Wednesday, December 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:40 PM Brussels, Brussels South (Gare du Midi) | 11h30 | 12:10 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 2:10 PM Brussels, Brussels South (Gare du Midi) | 12h10 | 2:20 AM Lyon, Perrache Bus Station | 1 transfer | |
50338 · 5133 | 6:05 PM Brussels, Brussels South (Gare du Midi) | 10h10 | 4:15 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 7:15 PM Brussels, Brussels South (Gare du Midi) | 10h30 | 5:45 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
| Thursday, December 4 | |||||
FlixBus · FlixBus | 12:30 AM Brussels, Brussels South (Gare du Midi) | 13h15 | 1:45 PM Lyon, Perrache Bus Station | 1 transfer | |
50326 · 5131 | 5:40 AM Brussels, Brussels South (Gare du Midi) | 12h05 | 5:45 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 9:05 AM Brussels, Gare Du Midi | 13h15 | 10:20 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 9:40 AM Brussels, Brussels South (Gare du Midi) | 12h40 | 10:20 PM Lyon, Perrache Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Brussels to Lyon
Buses from Brussels to Lyon run on average 20 times per day, taking around 9h 32m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 353 miles (569 km) distance in 9h 40m.
Distance 353 miles (569 km) |
Average bus duration 9h 32m |
Cheapest ticket price $24 (€19) |
Buses per day 20 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Brussels to LyonYou can travel by bus between Brussels to Lyon with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Brussels to Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

When departing from Brussels, you have various bus station options to start your trip from including Bruxelles, Gare du Nord and Brussels, Brussels South (Gare du Midi). When arriving in Lyon, you can end your journey in bus stations like Lyon, Perrache Bus Station and Lyon, Gare Perrache.
Passengers board the bus most frequently from Bruxelles, Gare du Nord, which is located around 1.1 miles (1.7 km) away from the city centre, and they get off the bus at Lyon, Perrache Bus Station, located 1.4 miles (2.3 km) away from the city centre.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Brussels to Lyon, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Brussels to Lyon
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:00
- Free Wi-Fi
- Available outside the main terminal.
- Elevators, ramps
- Available in the station.
- Bus: 272, 471 Train: IC, S2, S4
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Brussels
More options for your journey from Brussels to Lyon
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