- Must visit
Royal Museums of Fine Arts of Belgium
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Flights from Lyon to Brussels depart on average 12 times per day, taking around 2h 25m. Cheap flight tickets for this journey start at $114 (€92) but you can travel from only $27 (€22) by bus.
There are 2 flights per day. The earliest flight runs at 00:10, the last at 23:40. The fastest flight covers the 353 miles (569 km) distance in 1h 25m. April is the cheapest month to fly.
Distance 353 miles (569 km) |
Average flight duration 2h 25m |
Cheapest ticket price $114 (€92) |
Flights per day 12 |
Direct flights 2 |
Fastest flight 1h 25m |
First flight 12:10 AM |
Last flight 11:40 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 49 days |
Cheapest price
$210
Average price
$526
Fastest journey
1 h 25 m
Average duration
2 h 43 m
Flights per day
50
Distance
569 km
The best way to find a cheap flight ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $526 if you buy it on the day, but the cheapest tickets can be found for only $210.
Of the 50 flights that leave Lyon for Brussels onTue, Jun 02, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 02 the direct flights cover the 569 km distance in an average of 2 h 43 m but if you time it right, some flights will get you there in just 1 h 25 m .
On Tue, Jun 02 the longest flights will take 3 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
VY1223 · VY8986
VY1223 · VY8980
AF7365+
AF5476+
9398
AF7367+
AF8318+
9398
AF7363+
AF5476+
9398
SN3588
SN3594
KL1426+
KL1703
LH2247+
LH5580
OS354+
OS295Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $27. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $27, and a flight costs an average of $114.
Distance: 353 miles (569 km)
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
$312 Average price | $163 Average price | $59 Average price Cheapest | $198 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 7h 28m Average total duration (door-to-door) |
1.7 - 3.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Brussels:
A bus is $104 (€84) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $163 (€131).
A bus is $253 (€204) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $312 (€251).
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
The table below shows live departures for Lyon to Brussels flights for today, Monday, June 1. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AF1140+ 9388+ AF7365 | 11:20 AM Lyon Saint Exupery Airport | 9h46 | 9:06 PM Brussels-Midi | 2 transfers | |
AF1140+ 9398+ AF7365 | 11:20 AM Lyon Saint Exupery Airport | 11h46 | 11:06 PM Brussels-Midi | 2 transfers | |
AF8286+ 9398+ AF6134 | 12:30 PM Lyon Saint Exupery Airport | 10h36 | 11:06 PM Brussels-Midi | 2 transfers | |
AF3134+ 9398+ AF6024 | 12:40 PM Lyon Saint Exupery Airport | 10h26 | 11:06 PM Brussels-Midi | 2 transfers | |
OS354+ OS295 | 12:55 PM Lyon Saint Exupery Airport | 3h50 | 4:45 PM Brussels Airport | 1 transfer | |
SN3588 | 1:10 PM Lyon Saint Exupery Airport | 1h25 | 2:35 PM Brussels Airport | 0 transfersDirect | |
KL1432+ KL1707 | 2:05 PM Lyon Saint Exupery Airport | 8h10 | 10:15 PM Brussels Airport | 1 transfer | |
AF3223+ 9398 | 2:05 PM Lyon Saint Exupery Airport | 9h01 | 11:06 PM Brussels-Midi | 1 transfer | |
KL1432+ 9398 | 2:05 PM Lyon Saint Exupery Airport | 9h01 | 11:06 PM Brussels-Midi | 1 transfer | |
AF3223+ 9476 | 2:05 PM Lyon Saint Exupery Airport | 5h01 | 7:06 PM Brussels-Midi | 1 transfer | |
AF7367 · AF1440+ 9398 | 2:40 PM Lyon Saint Exupery Airport | 8h26 | 11:06 PM Brussels-Midi | 2 transfers | |
AF7367+ AF8318+ 9398 | 2:40 PM Lyon Saint Exupery Airport | 8h26 | 11:06 PM Brussels-Midi | 2 transfers | |
KL1434+ KL1707 | 6:15 PM Lyon Saint Exupery Airport | 4h00 | 10:15 PM Brussels Airport | 1 transfer | |
KL1434+ 9398 | 6:15 PM Lyon Saint Exupery Airport | 4h51 | 11:06 PM Brussels-Midi | 1 transfer | |
AF3224+ 9398 | 6:15 PM Lyon Saint Exupery Airport | 4h51 | 11:06 PM Brussels-Midi | 1 transfer | |
LH1079+ LH5590 | 6:55 PM Lyon Saint Exupery Airport | 3h40 | 10:35 PM Brussels Airport | 1 transfer | |
VY1225 · VY8986 | 10:45 PM Lyon Saint Exupery Airport | 15h45 | 2:30 PM Brussels Airport | 1 transfer | |
| Tuesday, June 2 | |||||
AF7371 · AF1340+ 9364 | 6:00 AM Lyon Saint Exupery Airport | 11h06 | 5:06 PM Brussels-Midi | 2 transfers | |
AF7371 · AF1340+ 9352 | 6:00 AM Lyon Saint Exupery Airport | 9h06 | 3:06 PM Brussels-Midi | 2 transfers | |
AF7371 · AF1340+ 9370 | 6:00 AM Lyon Saint Exupery Airport | 12h06 | 6:06 PM Brussels-Midi | 2 transfers | |
KL1426+ 9328 | 6:30 AM Lyon Saint Exupery Airport | 4h36 | 11:06 AM Brussels-Midi | 1 transfer | |
AF8316+ 9328 | 6:30 AM Lyon Saint Exupery Airport | 4h36 | 11:06 AM Brussels-Midi | 1 transfer | |
KL1426+ KL1705 | 6:30 AM Lyon Saint Exupery Airport | 8h10 | 2:40 PM Brussels Airport | 1 transfer | |
KL1426+ KL1703 | 6:30 AM Lyon Saint Exupery Airport | 3h10 | 9:40 AM Brussels Airport | 1 transfer | |
KL1426+ 9428 | 6:30 AM Lyon Saint Exupery Airport | 4h36 | 11:06 AM Brussels-Midi | 1 transfer | |
LH1083 · LH988+ 9370 | 6:55 AM Lyon Saint Exupery Airport | 11h11 | 6:06 PM Brussels-Midi | 2 transfers | |
LH1083 · LH988+ 9352 | 6:55 AM Lyon Saint Exupery Airport | 8h11 | 3:06 PM Brussels-Midi | 2 transfers | |
LH1083 · LH988+ 9364 | 6:55 AM Lyon Saint Exupery Airport | 10h11 | 5:06 PM Brussels-Midi | 2 transfers | |
LH1083+ LH5572 | 6:55 AM Lyon Saint Exupery Airport | 4h55 | 11:50 AM Brussels Airport | 1 transfer | |
SN3594 | 7:05 AM Lyon Saint Exupery Airport | 1h25 | 8:30 AM Brussels Airport | 0 transfersDirect | |
AF3215+ 9398+ AF6142 | 8:35 AM Lyon Saint Exupery Airport | 14h31 | 11:06 PM Brussels-Midi | 2 transfers | |
AF3215+ 9364+ AF6142 | 8:35 AM Lyon Saint Exupery Airport | 8h31 | 5:06 PM Brussels-Midi | 2 transfers | |
AF3215+ 9370+ AF6142 | 8:35 AM Lyon Saint Exupery Airport | 9h31 | 6:06 PM Brussels-Midi | 2 transfers | |
AF3140+ 9398+ AF6022 | 8:45 AM Lyon Saint Exupery Airport | 14h21 | 11:06 PM Brussels-Midi | 2 transfers | |
AF3140+ 9364+ AF6022 | 8:45 AM Lyon Saint Exupery Airport | 8h21 | 5:06 PM Brussels-Midi | 2 transfers | |
AF3140+ 9370+ AF6022 | 8:45 AM Lyon Saint Exupery Airport | 9h21 | 6:06 PM Brussels-Midi | 2 transfers | |
LH2247+ LH5580 | 9:25 AM Lyon Saint Exupery Airport | 3h45 | 1:10 PM Brussels Airport | 1 transfer | |
LH2247 · LH2304+ 9370 | 9:25 AM Lyon Saint Exupery Airport | 8h41 | 6:06 PM Brussels-Midi | 2 transfers | |
LH2247 · LH2304+ 9398 | 9:25 AM Lyon Saint Exupery Airport | 13h41 | 11:06 PM Brussels-Midi | 2 transfers | |
LH2247 · LH2306+ 9398 | 9:25 AM Lyon Saint Exupery Airport | 13h41 | 11:06 PM Brussels-Midi | 2 transfers | |
AF8320+ 9352 | 9:55 AM Lyon Saint Exupery Airport | 5h11 | 3:06 PM Brussels-Midi | 1 transfer | |
KL1428+ 9364 | 9:55 AM Lyon Saint Exupery Airport | 7h11 | 5:06 PM Brussels-Midi | 1 transfer | |
KL1428 · KL1705 | 9:55 AM Lyon Saint Exupery Airport | 4h45 | 2:40 PM Brussels Airport | 1 transfer | |
KL1428+ 9352 | 9:55 AM Lyon Saint Exupery Airport | 5h11 | 3:06 PM Brussels-Midi | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Dedicated to René Magritte, this museum holds the world's largest collection of his works. It is a standout stop for surrealism lovers and one of Brussels' most famous museums.
A contemporary art museum known for street art, digital culture, and youth-oriented exhibitions. It became especially popular with younger visitors and on social media.
A landscaped cultural hill linking the upper and lower city, known for its formal gardens and classic skyline view. It is one of Brussels' best walking and photography spots.
A beautiful 19th-century covered arcade with elegant glass roofing and historic atmosphere. It is one of the city's most photogenic and fashionable passages.
A grand urban park laid out around monumental buildings and the Cinquantenaire Arch. Ideal for a walk, photos, and combining with nearby museums.
Brussels’ classic pairing of mussels steamed with white wine, celery, and herbs, served with crisp fries. It is one of the city’s most iconic and widely loved meals.
A traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. It is a staple of local brasserie cuisine.
A comforting Brussels side dish of mashed potatoes mixed with seasonal vegetables such as carrots, leeks, or spinach, often served with sausage or meat.
Well-regarded Belgian restaurant serving regional classics, strong beer pairings, and seasonal ingredients in a cozy, old-Brussels dining room.
One of Brussels’ landmark fine-dining restaurants, celebrated for refined Belgian-influenced cuisine, polished service, and an elegant Art Nouveau setting.
Popular traditional restaurant near Sainte-Catherine known for generous Belgian comfort food, beer-based stews, and an unfussy, bustling atmosphere.
Moderate by Western European standards. Beer, waffles, and transit are reasonable; hotels and central dining cost more.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Round up taxi fares.
Official public transport app
Brussels Airport -> Bruxelles-Central Station, Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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