Travel Information from Lyon to Brussels
| 352 miles (568 km) | |
| Bus, train or flight | |
| $22 - $105 | |
| Bus • $22 (€20) • 9 h 40 min | |
| Flight • $105 (€95) • 1 h 25 min | |
| BlaBlaCar Bus, Brussels Airlines or SNCF | TGV |
Travel 352 miles (568 km) by bus, train or flight to Brussels from Lyon. The most popular travel companies which serve this trip are BlaBlaCar Bus, Brussels Airlines or SNCF | TGV among others. Travelers can even take a direct bus, flight or train from Lyon to Brussels.
Travel optionsfrom Lyon to Brussels
How to get from Lyon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.
4788 · 50327Cheapest
4788 · 50327Fastest
SN3588Other options
9868
9864
9862
58074 · 50337
FlixBus · FlixBus
FlixBus · FlixBus
VY1221 · VY8982
VY1221 · VY8986
VY1223 · VY8980Find all the dates and times for this journey by train, bus, flight, and ferry .
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How to get from Lyon to Brussels
The Best Way According to our Users
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FAQs: Travel from Lyon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

There are 3 ways to get from Lyon to Brussels: bus, train or flight.
The cheapest way to travel between Lyon and Brussels is a bus with an average price of $22 (€20).
This is compared to other travel options from Lyon to Brussels:
A bus is $83 (€75) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $105 (€95).
A bus is $54 (€49) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $76 (€69).
The fastest way to get to Brussels from Lyon is by flight with an average travel time of 1 h 25 min.
Other travel options to Brussels take longer:
Bus takes 9 h 40 min on average.
Train takes on average 3 h 41 min.
The Lyon to Brussels distance is around 352 miles (568 km).
The average frequency per day from Lyon to Brussels is:
- 23 buses a day.
- Around 10 flights per day.
- 5 trains a day.
However, we recommend checking specific travel dates for your journey from Lyon to Brussels as scheduled services by bus, train or flight can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Lyon to Brussels:
- Most travelers board their bus from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
- Most travelers board their plane from Lyon Saint Exupery Airport and arrive in Brussels Airport.
- Most travelers take a train from Lyon Part Dieu to Brussels-Midi.
Omio works with many trusted partners that can help you travel the best way from Lyon to Brussels:
- You can go to Brussels from Lyon by bus with BlaBlaCar Bus or FlixBus. You'll see cheap bus tickets for $22 (€20) with BlaBlaCar Bus from Lyon to Brussels on Omio.
- You can go to Brussels from Lyon by plane with Brussels Airlines, Lufthansa, KLM, Vueling Airlines, Lufthansa Cityline (2) or easyJet. You'll see cheap plane tickets for $105 (€95) with Vueling Airlines from Lyon to Brussels on Omio.
- You can take a train from Lyon to Brussels with SNCF | TGV or TGV INOUI. Cheap tickets can be found for $76 (€69) with SNCF | TGV from Lyon to Brussels.
Yes, there are direct services available from Lyon to Brussels with the following travel companies:
- Direct buses with FlixBus or BlaBlaCar Bus with 3 direct buses per day.
- 2 direct flights per day with Brussels Airlines.
- Direct trains with TGV INOUI with 5 direct trains per day.
Direct services tend to save you time and add more convenience in getting you to Brussels as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between Lyon and Brussels.
Travelling from Lyon to Brussels: related information
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