How to travel from Lyon to Brussels

Sat, Feb 28
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TGV
BlaBlaCar Bus
Brussels Airlines
TGV INOUI
FlixBus
1,000+ more
TGV
BlaBlaCar Bus
Brussels Airlines
TGV INOUI
FlixBus
1,000+ more
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Travel Information

Compare train, bus, and flight for Lyon to Brussels

Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $121.

Distance: 353 miles (569 km)

Compare train with

Most popular
Train
Bus
Flight

$136

Average price

$52

Average price

Cheapest

$282

Average price

6h 8m

Average total duration

5h 38m

Onboard

+

30m

Additional time*

8h 28m

Average total duration

7h 58m

Onboard

+

30m

Additional time*

4h 54m

Average total duration

Fastest

1h 54m

Onboard

+

3h 0m

Additional time*

0.2 - 0.5kg

CO2 emissions

Lowest

0.6 - 1.4kg

CO2 emissions

1.7 - 3.4kg

CO2 emissions

TGV

Most popular train company

BlaBlaCar Bus

Most popular bus company

Brussels Airlines

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Travel options
from Lyon to Brussels

How to get from Lyon to Brussels by train, bus or flight.

Our recommendation

bus

The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.

BlaBlaCar Bus50829
10:45PM9h40
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
08:25AMBrussels, Brussels South (Gare du Midi)
$691One-way
0 transfers

Cheapest

BlaBlaCar Bus50829
10:45PM9h40
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
08:25AMBrussels, Brussels South (Gare du Midi)
$691One-way
0 transfers

Fastest

Air FranceKL1426+KLM CityhopperKL1703
06:40AM3h30
Lyon Saint Exupery Airport
10:10AMBrussels Airport
$3361One-way
1 transfer

Other options

SNCF6692+Eurostar9327
07:34AM4h13
Lyon Part Dieu
11:47AMBrussels-Midi
$3301One-way
1 transfer
SNCF6614+Eurostar9447
10:50AM4h27
Gare de Lyon-Perrache
03:17PMBrussels-Midi
$3301One-way
1 transfer
SNCF6614+Eurostar9447
11:04AM4h13
Lyon Part Dieu
03:17PMBrussels-Midi
$3301One-way
1 transfer
BlaBlaCar Bus4788 · 50327
06:15AM10h15
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
04:30PMBrussels, Brussels South (Gare du Midi)
$761One-way
1 transfer
BlaBlaCar Bus4782 · 1466
02:40AM10h50
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
01:30PMBrussels, Brussels South (Gare du Midi)
$691One-way
1 transfer
BlaBlaCar Bus94742 · 1657
01:30AM10h30
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
12:00PMBrussels, Brussels South (Gare du Midi)
$811One-way
1 transfer
Air FranceKL1426+KLM CityhopperKL1705
06:40AM7h35
Lyon Saint Exupery Airport
02:15PMBrussels Airport
$3361One-way
1 transfer
Austrian AirlinesOS354 · OS295
12:50PM4h10
Lyon Saint Exupery Airport
05:00PMBrussels Airport
$3861One-way
1 transfer
Austrian AirlinesOS354 · OS297
12:50PM6h20
Lyon Saint Exupery Airport
07:10PMBrussels Airport
$3861One-way
1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Lyon to Brussels

The Best Way According to our Users

Whether it is for business or leisure, in order to travel from Lyon to Brussels, 87,95% of our customers choose the train as their preferred mode of transportation. By traveling by train on this route, you can enjoy the comfort of spacious seats, spectacular views—and in some cases free Wi-Fi—in both second and first class. Our customers have decided that the train is the best way to get from Lyon to Brussels and have chosen to enjoy this fast, safe and efficient way to arrive at their destination. Taking the train also avoids long lines or potential expenses for transfers to/from the station—especially since most main railway stations are located in the city center. Train companies in Europe vary from country to country, but most of them offer high-speed train routes, therefore when you add up at the end-to-end journey time, the train is often also the fastest way to get to your destination.

Search on Omio to find cheap tickets from Lyon to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Lyon to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

FAQs
There are 3 options to travel between Lyon and Brussels including taking a train, bus, and flight.
The cheapest way to travel from Lyon to Brussels is a bus with an average price of $24 (€19).

This is compared to other travel options from Lyon to Brussels:

A bus is $34 (€27) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $58 (€46).

A bus is $98 (€77) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $121 (€96).

The fastest way to travel from Lyon to Brussels is by flight with an average journey time of 1h 25m.

Other travel options to Brussels take longer:

Train takes on average 3h 43m.

Bus takes on average 9h 40m.

The distance from Lyon to Brussels is approximately 353 miles (569 km).
The average frequency per day from Lyon to Brussels is:
  • Around 16 buses per day.
  • Around 11 flights per day.
  • Around 4 trains per day.

However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Lyon to Brussels:
  • Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
  • Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
  • Buses mostly depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Lyon to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Brussels by bus.
  • Travel with Brussels Airlines, Air Baltic, Lufthansa, Vueling Airlines, KLM, CityJet, Lufthansa Cityline, SWISS, easyJet to go to Brussels by flight.
  • Travel with TGV, TGV INOUI to go to Brussels by train.
Yes, there are direct services available from Lyon to Brussels with the following travel companies:
  • 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
  • 2 direct flights per day with Brussels Airlines, Air Baltic, SWISS, easyJet.
  • 4 direct trains per day with TGV, TGV INOUI.
Omio customers who travel from Lyon to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
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