How to travel from Lyon to Brussels

Sat, Aug 29
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Travel by train, bus, flight with
SNCF | TGV INOUI
BlaBlaCar Bus
Brussels Airlines
TGV
FlixBus
1,000+ more
SNCF | TGV INOUI
BlaBlaCar Bus
Brussels Airlines
TGV
FlixBus
1,000+ more
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Travel Information

Compare train, bus, and flight for Lyon to Brussels

Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from Kč565. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of Kč565, and a flight costs an average of Kč1927.

Distance: 353 miles (569 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

Kč3000

Average price

Kč1050

Average price

Cheapest

Kč5552

Average price

Kč4136

Average price

(fuel + tolls)

5h 13m

Average total duration

4h 43m

Onboard

+

30m

Additional time*

8h 30m

Average total duration

8h 0m

Onboard

+

30m

Additional time*

4h 25m

Average total duration

Fastest

2h 25m

Onboard

+

2h 0m

Additional time*

7h 28m

Average total duration

(door-to-door)

0.2 - 0.5kg

CO2 emissions

Lowest

0.6 - 1.4kg

CO2 emissions

1.7 - 3.4kg

CO2 emissions

-

CO2 emissions

TGV

Most popular train company

BlaBlaCar Bus

Most popular bus company

Brussels Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Lyon to Brussels is a bus with an average price of Kč1050.

This is compared to other travel options from Lyon to Brussels:

A bus is Kč1950 less than a train for this route with tickets for a train from Lyon to Brussels costing on average Kč3000.

A bus is Kč4502 less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average Kč5552.

The fastest way to travel from Lyon to Brussels is by flight with an average journey time of 4h 25m.

Other travel options to Brussels take longer:

Train takes on average 5h 13m.

Bus takes on average 8h 30m.

It's helpful to compare your options as there are 3 ways to travel between Lyon and Brussels including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Lyon to Brussels among Omio's users.

Travel options
from Lyon to Brussels

How to get from Lyon to Brussels by train, bus or flight.

Our recommendation

bus

The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.

  • BlaBlaCar Bus58074 · 50337
    12:00 PM11h35
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    11:35 PMBrussels, Brussels South (Gare du Midi)
    9511One-way
    1 transfer

Cheapest

  • BlaBlaCar Bus58074 · 50337
    12:00 PM11h35
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    11:35 PMBrussels, Brussels South (Gare du Midi)
    9511One-way
    1 transfer

Fastest

  • Air BalticSN3594
    7:05 AM1h25
    Lyon Saint Exupery Airport
    8:30 AMBrussels Airport
    58571One-way
    0 transfers

Other options

  • SNCF | TGV INOUI9852
    5:42 AM4h03
    Lyon Part Dieu
    9:45 AMBrussels-Midi
    25711One-way
    0 transfers
  • TER17756+Eurostar9371
    9:16 AM10h03
    Lyon Part Dieu
    7:19 PMBrussels-Midi
    33581One-way
    1 transfer
  • TER17756+Eurostar9359
    9:16 AM8h03
    Lyon Part Dieu
    5:19 PMBrussels-Midi
    34871One-way
    1 transfer
  • BlaBlaCar Bus5130 · 50335
    10:40 AM11h50
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    10:30 PMBrussels, Brussels South (Gare du Midi)
    9511One-way
    1 transfer
  • BlaBlaCar Bus4788 · 1433
    6:15 AM11h15
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    5:30 PMBrussels, Brussels South (Gare du Midi)
    10791One-way
    1 transfer
  • BlaBlaCar Bus51707 · 98080
    7:35 AM11h35
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    7:10 PMBrussels, Brussels South (Gare du Midi)
    12851One-way
    1 transfer
  • Air FranceAF7365+KLMAF5476+Eurostar9376
    11:20 AM7h46
    Lyon Saint Exupery Airport
    7:06 PMBrussels-Midi
    62741One-way
    2 transfers
  • Air FranceAF7365+KLMAF5476+Eurostar9382
    11:20 AM8h46
    Lyon Saint Exupery Airport
    8:06 PMBrussels-Midi
    62741One-way
    2 transfers
  • Air FranceAF7365+KLMAF5476+Eurostar9482
    11:20 AM8h46
    Lyon Saint Exupery Airport
    8:06 PMBrussels-Midi
    62741One-way
    2 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Lyon to Brussels

The Best Way According to our Users

Whether it is for business or leisure, in order to travel from Lyon to Brussels, 87,95% of our customers choose the train as their preferred mode of transportation. By traveling by train on this route, you can enjoy the comfort of spacious seats, spectacular views—and in some cases free Wi-Fi—in both second and first class. Our customers have decided that the train is the best way to get from Lyon to Brussels and have chosen to enjoy this fast, safe and efficient way to arrive at their destination. Taking the train also avoids long lines or potential expenses for transfers to/from the station—especially since most main railway stations are located in the city center. Train companies in Europe vary from country to country, but most of them offer high-speed train routes, therefore when you add up at the end-to-end journey time, the train is often also the fastest way to get to your destination.

Search on Omio to find cheap tickets from Lyon to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Lyon to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

FAQs
There are 3 options to travel between Lyon and Brussels including taking a train, bus, and flight.
The cheapest way to travel from Lyon to Brussels is a bus with an average price of Kč980.

This is compared to other travel options from Lyon to Brussels:

A bus is Kč1994 less than a train for this route with tickets for a train from Lyon to Brussels costing on average Kč2975.

A bus is Kč4409 less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average Kč5390.

The fastest way to travel from Lyon to Brussels is by flight with an average journey time of 4h 25m.

Other travel options to Brussels take longer:

Train takes on average 5h 14m.

Bus takes on average 8h 30m.

The distance from Lyon to Brussels is approximately 353 miles (569 km).
The average frequency per day from Lyon to Brussels is:
  • Around 14 buses per day.
  • Around 13 flights per day.
  • Around 5 trains per day.

However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Lyon to Brussels:
  • Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
  • Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
  • Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Lyon to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar, Alsa to go to Brussels by bus.
  • Travel with Brussels Airlines, Air Baltic, Vueling, Austrian Airlines, KLM, Lufthansa, Swiss, easyJet to go to Brussels by flight.
  • Travel with SNCF | TGV INOUI, TGV, SNCF, TER to go to Brussels by train.
Yes, there are direct services available from Lyon to Brussels with the following travel companies:
  • 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
  • 2 direct flights per day with Brussels Airlines, Air Baltic, Swiss, easyJet.
  • 4 direct trains per day with SNCF | TGV INOUI, TGV.
Omio customers who travel from Lyon to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
Most travelers need at least three days in Brussels to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.
For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.
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