4.9
4.6
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $60 For those with little time, consider booking a train, which has an average total journey time of 4h 23m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $60, while a flight costs an average of $427.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$95 Average price | $60 Average price Cheapest | $427 Average price | $191 Average price (fuel + tolls) |
4h 23m Average total duration Fastest 3h 53m Onboard + 30m Additional time* | 10h 37m Average total duration 10h 7m Onboard + 30m Additional time* | 5h 6m Average total duration 3h 6m Onboard + 2h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Brussels:
A bus is $35 (€29) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $95 (€80).
A bus is $367 (€308) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $427 (€358).
Other travel options to Brussels take longer:
Flight takes on average 5h 6m.
Bus takes on average 10h 37m.
The journey is about 3h 35m faster (3h 53m by train vs 7h 28m by car) and roughly $96 (€81) cheaper once you factor in fuel and tolls ($95 (€80) vs $191 (€160)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Lyon to Brussels
How to get from Lyon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.
5130 · 5033510:40 AM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:30 PMBrussels, Brussels South (Gare du Midi)$311One-way1 transfer
Cheapest
- 5130 · 5033510:40 AM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:30 PMBrussels, Brussels South (Gare du Midi)$311One-way1 transfer
Fastest
- SN27249:15 PM1h15Geneva International Airport10:30 PMBrussels Airport$3261One-way0 transfers
Other options
- 98827:01 PM3h59Lyon Part Dieu11:00 PMBrussels-Midi$891One-way0 transfers
- 6628+
93936:04 PM4h43Lyon Part Dieu10:47 PMBrussels-Midi$981One-way1 transfer - 6626+93935:04 PM5h43Lyon Part Dieu10:47 PMBrussels-Midi$981One-way1 transfer
- 5132 · 165711:55 PM12h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)$361One-way1 transfer
- FlixBus9:25 PM10h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:15 AMBrussels, Brussels South (Gare du Midi)$391One-way0 transfers
- FlixBus · FlixBus3:15 PM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:05 AMBrussels, Brussels South (Gare du Midi)$551One-way1 transfer
AF7365+
AF5476+939811:20 AM11h46Lyon Saint Exupery Airport11:06 PMBrussels-Midi$2251One-way2 transfers
VY1223 · VY898610:45 PM15h45Lyon Saint Exupery Airport2:30 PMBrussels Airport$2291One-way1 transfer
SN35947:05 AM1h25Lyon Saint Exupery Airport8:30 AMBrussels Airport$2721One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Lyon to Brussels
The Best Way According to our Users
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FAQs: Travel from Lyon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.
This is compared to other travel options from Lyon to Brussels:
A bus is $35 (€29) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $95 (€80).
A bus is $367 (€308) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $427 (€358).
Other travel options to Brussels take longer:
Flight takes on average 5h 6m.
Bus takes on average 10h 37m.
- Around 16 trains per day.
- Around 15 flights per day.
- Around 14 buses per day.
However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with BlaBlaCar Bus, FlixBus to go to Brussels by bus.
- Travel with Brussels Airlines, Air Baltic, British Airways, Vueling, Austrian Airlines, Swiss, Lufthansa, BA Euroflyer, Lufthansa Cityline, KLM Cityhopper, Transavia France, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Bulgaria Air, Helvetic Airways, Lot Polish Airlines to go to Brussels by flight.
- Travel with SNCF | TGV INOUI, SNCF, TER, SNCF | TGV Lyria to go to Brussels by train.
- 2 direct buses per day with BlaBlaCar Bus, FlixBus.
- 2 direct flights per day with Air Baltic.
- 4 direct trains per day with SNCF | TGV INOUI.
Travelling from Lyon to Brussels: related information
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