How to travel from Lyon to Brussels

Wed, Apr 15
+ Add return
Travel by train, bus, flight with
TGV
BlaBlaCar Bus
Brussels Airlines
TGV INOUI
FlixBus
1,000+ more
TGV
BlaBlaCar Bus
Brussels Airlines
TGV INOUI
FlixBus
1,000+ more
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Travel Information

Compare train, bus, and flight for Lyon to Brussels

Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $121.

Distance: 353 miles (569 km)

Compare train with

Most popular
Train
Bus
Flight

$136

Average price

$52

Average price

Cheapest

$282

Average price

6h 8m

Average total duration

5h 38m

Onboard

+

30m

Additional time*

8h 28m

Average total duration

7h 58m

Onboard

+

30m

Additional time*

4h 54m

Average total duration

Fastest

1h 54m

Onboard

+

3h 0m

Additional time*

0.2 - 0.5kg

CO2 emissions

Lowest

0.6 - 1.4kg

CO2 emissions

1.7 - 3.4kg

CO2 emissions

TGV

Most popular train company

BlaBlaCar Bus

Most popular bus company

Brussels Airlines

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Travel options
from Lyon to Brussels

How to get from Lyon to Brussels by train, bus or flight.

Our recommendation

bus

The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.

  • BlaBlaCar Bus83134 · 50331
    8:30 AM11h15
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    7:45 PMBrussels, Brussels South (Gare du Midi)
    $361One-way
    1 transfer

Cheapest

  • BlaBlaCar Bus83134 · 50331
    8:30 AM11h15
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    7:45 PMBrussels, Brussels South (Gare du Midi)
    $361One-way
    1 transfer

Fastest

  • Air BalticSN3588
    1:10 PM1h25
    Lyon Saint Exupery Airport
    2:35 PMBrussels Airport
    $3101One-way
    0 transfers

Other options

  • SNCF6906+Eurostar9429
    7:54 AM4h23
    Lyon Saint-Exupéry TGV
    12:17 PMBrussels-Midi
    $2011One-way
    1 transfer
  • SNCF6908+Eurostar9351
    10:53 AM4h55
    Lyon Saint-Exupéry TGV
    3:48 PMBrussels-Midi
    $2151One-way
    1 transfer
  • SNCF6906+Eurostar9329
    7:54 AM4h23
    Lyon Saint-Exupéry TGV
    12:17 PMBrussels-Midi
    $2201One-way
    1 transfer
  • BlaBlaCar Bus51470 · 1613
    3:50 PM10h23
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    2:13 AMBrussels, Brussels South (Gare du Midi)
    $381One-way
    1 transfer
  • BlaBlaCar Bus58074 · 50337
    12:00 PM11h35
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    11:35 PMBrussels, Brussels South (Gare du Midi)
    $481One-way
    1 transfer
  • BlaBlaCar Bus50618 · 1657
    1:20 AM10h40
    Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    12:00 PMBrussels, Brussels South (Gare du Midi)
    $581One-way
    1 transfer
  • Air FranceAF7371+KLMAF8382+Eurostar9364
    6:00 AM11h06
    Lyon Saint Exupery Airport
    5:06 PMBrussels-Midi
    $3631One-way
    2 transfers
  • Air FranceAF7371+KLMAF8382+Eurostar9370
    6:00 AM12h06
    Lyon Saint Exupery Airport
    6:06 PMBrussels-Midi
    $3631One-way
    2 transfers
  • Air FranceAF7371+KLMAF8382+Eurostar9382
    6:00 AM14h06
    Lyon Saint Exupery Airport
    8:06 PMBrussels-Midi
    $3631One-way
    2 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Apr 15
Thu
Apr 16
Fri
Apr 17
Sat
Apr 18
Sun
Apr 19
Mon
Apr 20
Tue
Apr 21
Wed
Apr 22
Thu
Apr 23
Fri
Apr 24
Sat
Apr 25
Sun
Apr 26
Mon
Apr 27
Tue
Apr 28
Wed
Apr 29
Thu
Apr 30
Fri
May 01
Sat
May 02
Sun
May 03
Mon
May 04
Tue
May 05

How to get from Lyon to Brussels

The Best Way According to our Users

Whether it is for business or leisure, in order to travel from Lyon to Brussels, 87,95% of our customers choose the train as their preferred mode of transportation. By traveling by train on this route, you can enjoy the comfort of spacious seats, spectacular views—and in some cases free Wi-Fi—in both second and first class. Our customers have decided that the train is the best way to get from Lyon to Brussels and have chosen to enjoy this fast, safe and efficient way to arrive at their destination. Taking the train also avoids long lines or potential expenses for transfers to/from the station—especially since most main railway stations are located in the city center. Train companies in Europe vary from country to country, but most of them offer high-speed train routes, therefore when you add up at the end-to-end journey time, the train is often also the fastest way to get to your destination.

Search on Omio to find cheap tickets from Lyon to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Lyon to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

FAQs
There are 3 options to travel between Lyon and Brussels including taking a train, bus, and flight.
The cheapest way to travel from Lyon to Brussels is a bus with an average price of $24 (€19).

This is compared to other travel options from Lyon to Brussels:

A bus is $34 (€27) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $58 (€46).

A bus is $97 (€77) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $121 (€96).

The fastest way to travel from Lyon to Brussels is by flight with an average journey time of 1h 25m.

Other travel options to Brussels take longer:

Train takes on average 3h 43m.

Bus takes on average 9h 40m.

The distance from Lyon to Brussels is approximately 353 miles (569 km).
The average frequency per day from Lyon to Brussels is:
  • Around 16 buses per day.
  • Around 11 flights per day.
  • Around 4 trains per day.

However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Lyon to Brussels:
  • Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
  • Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
  • Buses mostly depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Lyon to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with Brussels Airlines, Air Baltic, Lufthansa, Vueling Airlines, KLM, Cityjet, Swiss, easyJet to go to Brussels by flight.
  • Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Brussels by bus.
  • Travel with TGV, TGV INOUI to go to Brussels by train.
Yes, there are direct services available from Lyon to Brussels with the following travel companies:
  • 2 direct flights per day with Brussels Airlines, Air Baltic, Swiss, easyJet.
  • 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
  • 4 direct trains per day with TGV, TGV INOUI.
Omio customers who travel from Lyon to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
HomeTravelTravel to BelgiumTravel to BrusselsHow to travel from Lyon to Brussels

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone