How to travel from Lyon to Brussels

Wed, Jan 14
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Brussels Airlines
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Travel options
from Lyon to Brussels

How to get from Lyon to Brussels by train, bus or flight.

Our recommendation

bus

The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.

BlaBlaCar Bus5130 · 50337
10:40AM12h55
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
11:35PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer

Cheapest

BlaBlaCar Bus5130 · 50337
10:40AM12h55
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
11:35PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer

Fastest

Brussels AirlinesSN3588
11:50AM1h25
Lyon Saint Exupery Airport
01:15PMBrussels Airport
$3081One-way
0 transfers

Other options

TGV INOUI9854
08:27AM3h59
Lyon Part Dieu
12:26PMBrussels-Midi
$1171One-way
0 transfers
TGV INOUI9862
11:00AM4h26
Lyon Part Dieu
03:26PMBrussels-Midi
$1311One-way
0 transfers
TGV INOUI9868
05:00PM3h43
Lyon Part Dieu
08:43PMBrussels-Midi
$1381One-way
0 transfers
FlixBusFlixBus · FlixBus
09:10AM15h25
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
12:35AMBrussels, Brussels South (Gare du Midi)
$521One-way
1 transfer
FlixBusFlixBus · FlixBus
12:50AM11h55
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
12:45PMBrussels, Brussels South (Gare du Midi)
$651One-way
1 transfer
FlixBusFlixBus · FlixBus
12:10AM12h10
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
12:20PMBrussels, Brussels South (Gare du Midi)
$641One-way
1 transfer
Brussels AirlinesSN3594
07:00AM1h25
Lyon Saint Exupery Airport
08:25AMBrussels Airport
$3081One-way
0 transfers
Air FranceAF7365 · AF1140+Eurostar9398
03:00PM8h06
Lyon Saint Exupery Airport
11:06PMBrussels-Midi
$2861One-way
2 transfers
Air FranceAF7371 · AF1500+Eurostar9388
06:55AM14h11
Lyon Saint Exupery Airport
09:06PMBrussels-Midi
$2911One-way
2 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

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How to get from Lyon to Brussels

The Best Way According to our Users

Whether it is for business or leisure, in order to travel from Lyon to Brussels, 87,95% of our customers choose the train as their preferred mode of transportation. By traveling by train on this route, you can enjoy the comfort of spacious seats, spectacular views—and in some cases free Wi-Fi—in both second and first class. Our customers have decided that the train is the best way to get from Lyon to Brussels and have chosen to enjoy this fast, safe and efficient way to arrive at their destination. Taking the train also avoids long lines or potential expenses for transfers to/from the station—especially since most main railway stations are located in the city center. Train companies in Europe vary from country to country, but most of them offer high-speed train routes, therefore when you add up at the end-to-end journey time, the train is often also the fastest way to get to your destination.

Search on Omio to find cheap tickets from Lyon to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Lyon to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

FAQs

There are 3 ways to get from Lyon to Brussels: bus, train or flight.

The cheapest way to travel between Lyon and Brussels is a bus with an average price of $22 (€20).

This is compared to other travel options from Lyon to Brussels:

A bus is $83 (€75) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $105 (€95).

A bus is $54 (€49) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $76 (€69).

The fastest way to get to Brussels from Lyon is by flight with an average travel time of 1 h 25 min.

Other travel options to Brussels take longer:

Bus takes 9 h 40 min on average.

Train takes on average 3 h 41 min.

The Lyon to Brussels distance is around 352 miles (568 km).

The average frequency per day from Lyon to Brussels is:

  • 23 buses a day.
  • Around 10 flights per day.
  • 5 trains a day.

However, we recommend checking specific travel dates for your journey from Lyon to Brussels as scheduled services by bus, train or flight can vary by season or day of the week.

These are the most popular departure and arrival points when traveling from Lyon to Brussels:

  • Most travelers board their bus from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
  • Most travelers board their plane from Lyon Saint Exupery Airport and arrive in Brussels Airport.
  • Most travelers take a train from Lyon Part Dieu to Brussels-Midi.

Omio works with many trusted partners that can help you travel the best way from Lyon to Brussels:

  • You can go to Brussels from Lyon by bus with BlaBlaCar Bus or FlixBus. You'll see cheap bus tickets for $22 (€20) with BlaBlaCar Bus from Lyon to Brussels on Omio.
  • You can go to Brussels from Lyon by plane with Brussels Airlines, Lufthansa, KLM, Vueling Airlines, Lufthansa Cityline (2) or easyJet. You'll see cheap plane tickets for $105 (€95) with Vueling Airlines from Lyon to Brussels on Omio.
  • You can take a train from Lyon to Brussels with SNCF | TGV or TGV INOUI. Cheap tickets can be found for $76 (€69) with SNCF | TGV from Lyon to Brussels.

Yes, there are direct services available from Lyon to Brussels with the following travel companies:

  • Direct buses with FlixBus or BlaBlaCar Bus with 3 direct buses per day.
  • 2 direct flights per day with Brussels Airlines.
  • Direct trains with TGV INOUI with 5 direct trains per day.

Direct services tend to save you time and add more convenience in getting you to Brussels as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between Lyon and Brussels.

Looking to extend your trip from Lyon to Brussels? Many Omio customers who go from Lyon to Brussels usually extend their vacation to explore other popular destinations like Paris, Amsterdam, Bruges, London or Berlin. If you're looking to explore Paris, Amsterdam, Bruges, London or Berlin from Brussels, let Omio find you the best connections available at an affordable price.
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