- Must visit
The Charleston Museum
Often called America's first museum, it covers Charleston and Lowcountry history, decorative arts, natural history, and regional culture.
Cheapest price
$151
Average price
$206
Fastest journey
1 d 6 h 35 m
Average duration
1 d 12 h 55 m
Buses per day
2
Distance
1097 km
The best way to find a cheap bus ticket from Detroit, MI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Charleston, SC will cost around $206 if you buy it on the day, but the cheapest tickets can be found for only $151.
Of the 2 buses that leave Detroit, MI for Charleston, SC on Sat, Jun 27, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct buses cover the 1097 km distance in an average of 1 d 12 h 55 m but if you time it right, some buses will get you there in just 1 d 6 h 35 m .
On Sat, Jun 27 the slowest buses will take 1 d 19 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Detroit, MI to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $119. For those with little time consider booking a flight which can get you there in 2h 52m. The ticket price range depends on the travel mode: a bus costs an average of $119, and a train costs an average of $274.
Distance: 681 miles (1097 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$228 Average price Cheapest | $457 Average price | $275 Average price | $178 Average price (fuel + tolls) |
37h 22m Average total duration 36h 52m Onboard + 30m Additional time* | 27h 55m Average total duration 27h 25m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 2h 52m Onboard + 3h 0m Additional time* | 13h 0m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Detroit, MI to Charleston, SC:
A bus is $47 (€38) less than a flight for this route with tickets for a flight from Detroit, MI to Charleston, SC costing on average $275 (€225).
A bus is $229 (€188) less than a train for this route with tickets for a train from Detroit, MI to Charleston, SC costing on average $457 (€374).
Other travel options to Charleston, SC take longer:
Train takes on average 27h 25m.
Bus takes on average 36h 52m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:15AM | Arrival Time 10:30PM | Duration 43h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 04:15AM | Arrival Time 11:30PM | Duration 43h15 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $204 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 10:30PM | Duration 30h35 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $149 |
Operator Greyhound | Departure Time 04:55PM | Arrival Time 11:30PM | Duration 30h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $174 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 11:30PM | Duration 30h10 | Departure days Thu | Cheapest price $119 |
The table below shows live departures for Detroit, MI to Charleston, SC buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:55 PM Detroit, MI | 30h35 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 4:55 PM Detroit, MI | 30h35 | 11:30 PM Charleston, SC | 0 transfersDirect | |
| Sunday, June 21 | |||||
![]() | 3:15 AM Detroit, MI | 43h15 | 10:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Charleston, SC run on average 3 times per day, taking around 36h 52m. Cheap bus tickets for this journey start at $119 (€97) but you can travel from only $91 (€74) by flight.
The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 681 miles (1097 km) distance in 30h 10m.
Distance 681 miles (1097 km) |
Average bus duration 36h 52m |
Cheapest ticket price $119 (€97) |
Buses per day 3 |
Fastest bus 30h 10m |
First bus 5:00 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 77 days |
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
Often called America's first museum, it covers Charleston and Lowcountry history, decorative arts, natural history, and regional culture.
A small but important museum interpreting the domestic slave trade in Charleston through exhibits in a historic market building.
Charleston's leading art museum, known for American art with strong ties to the South, rotating exhibitions, and a distinguished permanent collection.
Charleston's famous waterfront promenade is lined with grand historic homes, harbor views, and classic postcard scenery.
A popular riverfront park known for its pier, lawns, and the photogenic Pineapple Fountain.
Charleston's best-known commercial corridor, mixing historic architecture, shopping, nightlife, and frequent social media visibility.
A Lowcountry classic of sautéed shrimp served over creamy grits, often with bacon or gravy. It is one of Charleston’s signature dishes.
A rich Charleston soup made with crab meat, crab roe, cream, and sherry. It is a historic local specialty associated with the city’s coastal cuisine.
A traditional rice and field pea dish, usually cooked with pork for flavor. It is an iconic Southern and Lowcountry comfort food.
One of Charleston’s most acclaimed restaurants, serving ingredient-driven Southern cuisine with a polished but approachable feel. Reservations are highly sought after.
A popular waterfront restaurant known for Lowcountry seafood, shrimp and grits, and relaxed harbor views. It is a dependable choice for classic Charleston flavors.
A celebrated restaurant focused on refined Southern cooking using seasonal local ingredients. Stylish and upscale, it is one of Charleston’s best-known dining rooms.
Prices are moderate by U.S. standards. Historic district dining and hotels cost more, while casual food and transport stay manageable.
Tip 18-20% in restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet. Tipping is expected for most service roles.
Find answers to the most common questions about traveling from Detroit, MI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Charleston, SC buses use the Detroit, Greyhound Terminal to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Detroit, MI and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need