- Must visit
USS Midway Museum
A large aircraft carrier museum on the waterfront with restored aircraft, flight deck views, and naval history exhibits. One of the city’s signature attractions.
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The cheapest and fastest buses from Chicago, IL to San Diego, CA
Showing times and prices for May 24
Cheapest price
$149
Average price
$288
Fastest journey
2 d 3 h 5 m
Average duration
2 d 7 h 40 m
Buses per day
7
Distance
2784 km
Cheap tickets
The best way to find a cheap bus ticket from Chicago, IL to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to San Diego, CA will cost around $288 if you buy it on the day, but the cheapest tickets can be found for only $149.
Fast buses
Of the 7 buses that leave Chicago, IL for San Diego, CA on Sun, May 24, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, May 24 the direct buses cover the 2784 km distance in an average of 2 d 7 h 40 m but if you time it right, some buses will get you there in just 2 d 3 h 5 m .
On Sun, May 24 the slowest buses will take 2 d 11 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:30 PM55h45Chicago, IL5:15 AMSan Diego, CA$1491One-way0 transfers- 10:15 PM51h05Chicago, IL1:20 AMSan Diego, CA$1901One-way0 transfers
- 6:15 AM59h50Chicago, IL6:05 PMSan Diego, CA$2091One-way0 transfers
- 5:15 AM59h50Chicago, IL5:05 PMSan Diego, CA$2141One-way0 transfers
- 5:10 AM73h05Chicago, IL6:15 AMSan Diego, CA$3401One-way0 transfers
- 10:15 PM51h05Chicago, IL1:20 AMSan Diego, CA$1901One-way0 transfers
- 10:30 PM55h45Chicago, IL6:15 AMSan Diego, CA$5331One-way0 transfers
- 9:30 PM55h45Chicago, IL5:15 AMSan Diego, CA$1491One-way0 transfers
- 5:25 PM55h55Chicago, IL1:20 AMSan Diego, CA$3831One-way0 transfers
- 6:15 AM59h50Chicago, IL6:05 PMSan Diego, CA$2091One-way0 transfers
Travel Information
Compare train, bus, and flight for Chicago, IL to San Diego, CA
Omio recommends booking the train as it is the most popular option from Chicago, IL to San Diego, CA among Omio's users. If you are prioritising price take the flight with prices starting from $59. For those with little time consider booking a flight which can get you there in 4h 53m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.8 - 2.5kg. The ticket price range depends on the travel mode: a flight costs an average of $59, and a train costs an average of $198.
Distance: 1729 miles (2784 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$307 Average price | $452 Average price | $305 Average price Cheapest | $435 Average price (fuel + tolls) |
47h 19m Average total duration 46h 49m Onboard + 30m Additional time* | 50h 4m Average total duration 49h 34m Onboard + 30m Additional time* | 7h 53m Average total duration Fastest 4h 53m Onboard + 3h 0m Additional time* | 30h 9m Average total duration (door-to-door) |
2.8 - 7.0kg CO2 emissions | 0.8 - 2.5kg CO2 emissions Lowest | 8.4 - 16.7kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Chicago, IL to San Diego, CA is a flight with an average price of $305 (€246).
This is compared to other travel options from Chicago, IL to San Diego, CA:
A flight is $3 (€2) less than a bus for this route with tickets for a bus from Chicago, IL to San Diego, CA costing on average $307 (€249).
A flight is $147 (€119) less than a train for this route with tickets for a train from Chicago, IL to San Diego, CA costing on average $452 (€365).
The fastest way to travel from Chicago, IL to San Diego, CA is by flight with an average journey time of 4h 53m.
Other travel options to San Diego, CA take longer:
Bus takes on average 46h 49m.
Train takes on average 49h 34m.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and San Diego, CA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Chicago, IL to San Diego, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Chicago, IL to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:10AM | Arrival Time 05:15AM | Duration 73h05 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price $355 |
Operator Greyhound | Departure Time 04:50AM | Arrival Time 05:05PM | Duration 60h15 | Departure days Fri | Cheapest price $154 |
Operator Greyhound | Departure Time 05:10AM | Arrival Time 06:15AM | Duration 73h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $269 |
Operator Greyhound | Departure Time 05:15AM | Arrival Time 05:05PM | Duration 59h50 | Departure days Thu, Sun | Cheapest price $142 |
Operator Greyhound | Departure Time 06:15AM | Arrival Time 06:05PM | Duration 59h50 | Departure days Sun | Cheapest price $209 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 01:20AM | Duration 58h05 | Departure days Sat | Cheapest price $264 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 06:15AM | Duration 62h15 | Departure days Tue, Sat | Cheapest price $296 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 09:40PM | Duration 53h20 | Departure days Tue | Cheapest price $131 |
Operator Greyhound | Departure Time 05:01PM | Arrival Time 09:10PM | Duration 52h09 | Departure days Tue | Cheapest price $185 |
Operator Greyhound | Departure Time 05:25PM | Arrival Time 09:40PM | Duration 52h15 | Departure days Wed, Thu, Fri, Sun | Cheapest price $207 |
Operator Greyhound | Departure Time 06:01PM | Arrival Time 10:10PM | Duration 52h09 | Departure days Tue, Fri, Sat | Cheapest price $388 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 05:15AM | Duration 57h30 | Departure days Wed | Cheapest price $403 |
Operator Greyhound | Departure Time 08:45PM | Arrival Time 06:15AM | Duration 57h30 | Departure days Tue, Wed | Cheapest price $346 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 01:10AM | Duration 51h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $144 |
Operator Greyhound | Departure Time 10:15PM | Arrival Time 05:15AM | Duration 55h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $163 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 06:15AM | Duration 55h45 | Departure days Thu, Sat, Sun | Cheapest price $460 |
Live departures
Chicago, IL to San Diego, CA bus times
The table below shows live departures for Chicago, IL to San Diego, CA buses for today, Saturday, May 23. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:15 PM Chicago, IL | 58h05 | 1:20 AM San Diego, CA | 0 transfersDirect | |
| 4:00 PM Chicago, IL | 57h45 | 1:45 AM San Diego, CA | 0 transfersDirect | |
| 6:01 PM Chicago, IL | 51h09 | 9:10 PM San Diego, CA | 0 transfersDirect | |
| 9:30 PM Chicago, IL | 55h40 | 5:10 AM San Diego, CA | 0 transfersDirect | |
| 10:15 PM Chicago, IL | 51h05 | 1:20 AM San Diego, CA | 0 transfersDirect | |
| 10:30 PM Chicago, IL | 55h45 | 6:15 AM San Diego, CA | 0 transfersDirect | |
| Sunday, May 24 | |||||
| 5:10 AM Chicago, IL | 73h05 | 6:15 AM San Diego, CA | 0 transfersDirect | |
| 5:15 AM Chicago, IL | 59h50 | 5:05 PM San Diego, CA | 0 transfersDirect | |
| 6:15 AM Chicago, IL | 59h50 | 6:05 PM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 24
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Why should you book Chicago, IL to San Diego, CA buses with Omio?
Greyhound as well as FlixBus offer buses services from Chicago, IL to San Diego, CA.
Omio is an official ticket reseller for all your travel options from Chicago, IL to San Diego, CA.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Chicago, IL to San Diego, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to San Diego, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Chicago, IL to San Diego, CA.
Journey information
Overview: Bus from Chicago, IL to San Diego, CA
USAUSA
Buses from Chicago, IL to San Diego, CA run on average 14 times per day, taking around 46h 49m. Cheap bus tickets for this journey start at $131 (€106) but you can travel from only $59 (€48) by flight.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1729 miles (2784 km) distance in 50h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $59 (€48)
Distance 1729 miles (2784 km) |
Average bus duration 46h 49m |
Cheapest ticket price $131 (€106) |
Buses per day 14 |
Fastest bus 50h 30m |
First bus 12:15 AM |
Last bus 11:10 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $59 (€48)
Bus providers: Greyhound, FlixBus from Chicago, IL to San Diego, CAYou can travel by bus between Chicago, IL to San Diego, CA with Greyhound, FlixBus for as low as $59 (€48). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
53h 10m
Cheapest Price
$618 (€500)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
50h 30m
Cheapest Price
$131 (€106)
Greyhound frequency
15 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Diego
Things to do in San Diego
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
- Recommended
San Diego Museum of Art
Balboa Park’s major art museum, known for European old masters, Asian art, and rotating exhibitions in a landmark Spanish Colonial Revival building.
- Recommended
Museum of Contemporary Art San Diego
Contemporary art museum with strong regional and international programming, especially noted for its oceanfront La Jolla location and modern exhibitions.
- Must visit
Balboa Park
San Diego’s flagship urban park, packed with gardens, museums, Spanish Colonial architecture, plazas, and highly photogenic walking paths.
- Must visit
La Jolla Cove
A scenic coastal area known for sea lions, cliffs, turquoise water, and one of the city’s most photographed ocean viewpoints.
- Must visit
Gaslamp Quarter
The city’s best-known historic downtown district, lined with Victorian-era buildings, lively streets, and a strong day-to-night atmosphere.
Fish Tacos
Beer-battered or grilled fish in a tortilla, usually topped with cabbage, crema, and salsa. A signature San Diego favorite shaped by Baja California influence.
California Burrito
A San Diego staple burrito filled with carne asada, fries, cheese, and salsa. It is one of the city’s most iconic late-night and taqueria foods.
Carne Asada Fries
French fries topped with carne asada, cheese, guacamole, sour cream, and salsa. This indulgent border-style dish is strongly associated with San Diego taco shops.
Mitch's Seafood
Established waterfront seafood restaurant in Point Loma known for fresh local catch, fish sandwiches, and harbor views.
Las Cuatro Milpas
Legendary casual spot in Barrio Logan known for traditional Mexican plates, handmade tortillas, and an old-school local atmosphere.
Oscar's Mexican Seafood
Popular casual venue celebrated for fish tacos, smoked fish tacos, and fresh coastal Baja-style seafood in a laid-back setting.
United States Dollar
San Diego is pricey by U.S. standards, especially for hotels and dining, though tacos, casual eats, and happy hours can help keep daily costs lower.
Average meal costs
- Budget
- USD 10-18 for tacos, fast food, or casual counter service.
- Mid-range
- USD 25-45 per person at a standard sit-down restaurant.
- Fine dining
- USD 80+ per person before drinks, tax, and tip.
- Coffee
- USD 4-7 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up or 10-15% for taxis, and USD 2-5 nightly for hotel housekeeping.
FAQs: Bus from Chicago, IL to San Diego, CA
Find answers to the most common questions about traveling from Chicago, IL to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Chicago, IL to San Diego, CA can start from as little as $131 (€106) when you book in advance. The average bus ticket price for Chicago, IL to San Diego, CA is $307 (€249) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to San Diego, CA is 50h 30m to travel the 1729 miles (2784 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to San Diego, CA leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to San Diego, CA leaves at 11:10 PM.
There are 14 buses a day from Chicago, IL to San Diego, CA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Chicago, IL to San Diego, CA, you can count on Greyhound, FlixBus for the best way to get you to San Diego, CA. You can also check all possible bus companies who offer a service between Chicago, IL and San Diego, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Diego, CA from Chicago, IL is worth doing but not as a day trip with a journey time of 50h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Chicago, IL to San Diego, CA is January.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and San Diego, CA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Chicago, IL to San Diego, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Chicago, IL to San Diego, CA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in San Diego, CA are:
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
Whether you can cancel your bus ticket from Chicago, IL to San Diego, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Chicago, IL to San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Chicago, IL to San Diego, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Chicago, IL to San Diego, CA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Chicago, IL to San Diego, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Chicago, IL to San Diego, CA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Chicago, IL to San Diego, CA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Chicago, IL to San Diego, CA with the following bus company: Greyhound, FlixBus.
Since neither Chicago, IL nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Chicago, IL to San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Chicago, IL to San Diego, CA
Chicago
San Diego
The major bus station for departures in Chicago is Chicago, Union Station (Amtrak). Find all the information you need to know about services, amenities and connections at Chicago, Union Station (Amtrak) for your trip from Chicago to San Diego.
Chicago, Union Station (Amtrak)
information
Chicago, Greyhound Bus Station
information
The major bus station for arrivals in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip to San Diego from Chicago.
San Diego, Congress Street (Old Town Park)
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
San Diego, San Ysidro Transit Center
information
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and Chicago, IL
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