- Must visit
Greensboro Science Center
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
Cheapest price
$143
Average price
$156
Fastest journey
21 h 10 m
Average duration
23 h 42 m
Buses per day
7
Distance
934 km
The best way to find a cheap bus ticket from Chicago, IL to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Greensboro, NC will cost around $156 if you buy it on the day, but the cheapest tickets can be found for only $143.
It's difficult to get from Chicago, IL to Greensboro, NC without transferring at least once.
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FlixBus · FlixBus
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FlixBusOmio recommends booking the train as it is the most popular option from Chicago, IL to Greensboro, NC among Omio's users. If you are prioritising price take the bus with prices starting from $102. For those with little time consider booking a flight which can get you there in 5h 13m. The ticket price range depends on the travel mode: a bus costs an average of $102, and a train costs an average of $163.
Distance: 580 miles (934 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$139 Average price Cheapest | $237 Average price | $220 Average price | $169 Average price (fuel + tolls) |
21h 30m Average total duration 21h 0m Onboard + 30m Additional time* | 24h 29m Average total duration 23h 59m Onboard + 30m Additional time* | 8h 13m Average total duration Fastest 5h 13m Onboard + 3h 0m Additional time* | 11h 25m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Chicago, IL to Greensboro, NC:
A bus is $81 (€66) less than a flight for this route with tickets for a flight from Chicago, IL to Greensboro, NC costing on average $220 (€180).
A bus is $98 (€80) less than a train for this route with tickets for a train from Chicago, IL to Greensboro, NC costing on average $237 (€194).
Other travel options to Greensboro, NC take longer:
Bus takes on average 21h 0m.
Train takes on average 23h 59m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:00AM | Arrival Time 01:10AM | Duration 25h10 | Departure days Sun | Cheapest price $227 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 05:35AM | Duration 25h45 | Departure days Sun | Cheapest price $109 |
Operator Greyhound | Departure Time 05:10AM | Arrival Time 05:35AM | Duration 24h25 | Departure days Sun | Cheapest price $164 |
Operator Greyhound | Departure Time 06:10AM | Arrival Time 07:50AM | Duration 24h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $112 |
Operator Greyhound | Departure Time 09:55AM | Arrival Time 10:55AM | Duration 24h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $107 |
Operator Greyhound | Departure Time 10:15AM | Arrival Time 10:55AM | Duration 23h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $107 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:55PM | Duration 21h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $118 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 08:10PM | Duration 25h10 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $138 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 04:55PM | Duration 21h10 | Departure days Sat | Cheapest price $184 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 01:10AM | Duration 25h20 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $134 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 01:10AM | Duration 25h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $134 |
The table below shows live departures for Chicago, IL to Greensboro, NC buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:45 PM Chicago, IL | 21h10 | 4:55 PM Greensboro, NC | 0 transfersDirect | |
| Sunday, June 21 | |||||
· | 6:10 AM Chicago, Greyhound Bus Station | 24h40 | 7:50 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 1 transfer | |
· | 9:55 AM Chicago, Greyhound Bus Station | 24h00 | 10:55 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 1 transfer | |
· | 10:15 AM Chicago, Union Station (Amtrak), IL | 23h40 | 10:55 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Chicago, IL to Greensboro, NC run on average 6 times per day, taking around 21h 0m. Cheap bus tickets for this journey start at $102 (€83) if you book in advance.
The earliest bus runs at 00:20, the last at 23:25. The fastest bus covers the 580 miles (934 km) distance in 21h 10m.
Distance 580 miles (934 km) |
Average bus duration 21h 0m |
Cheapest ticket price $102 (€83) |
Buses per day 6 |
Fastest bus 21h 10m |
First bus 12:20 AM |
Last bus 11:25 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 21 days |
Discover the best of Greensboro — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro trip today.
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
A nationally significant museum at the former Woolworth building, interpreting the Greensboro sit-ins and the civil rights movement.
The university art museum with a strong modern and contemporary collection, widely regarded as one of the city’s best cultural stops.
The city’s main walkable core, mixing historic blocks, murals, theaters, museums, and nightlife-oriented public spaces.
A large historic park with trails, monuments, and interpretive stops, combining outdoor walking with Revolutionary War history.
A landscaped public garden with seasonal color, sculptures, and easy paths, popular for photos and quiet walks.
Slow-smoked pork shoulder chopped or pulled and dressed in a tangy vinegar-based sauce, a classic Piedmont and statewide barbecue tradition.
A regional red slaw made with cabbage and a lightly sweet vinegar-tomato dressing, commonly served on barbecue sandwiches across central North Carolina.
Fluffy Southern biscuits filled with salty cured ham, a breakfast staple in North Carolina and a familiar comfort food in Greensboro.
A popular casual spot recognized for creative burgers, good beer selection, and lively neighborhood energy.
A polished bistro at Proximity Hotel known for seasonal American fare, strong brunch, and an upscale yet relaxed setting.
An established restaurant offering European-influenced American cuisine, dependable service, and a refined dining room popular for dinner and brunch.
Costs are generally moderate for U.S. travel, with affordable dining and parking, while hotels vary by season and events.
Tip 18-20% at restaurants; 20%+ for excellent service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Chicago, IL to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

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