- Must visit
The Art Institute Of Chicago
One of the premier art museums in the United States, known for its Impressionist masterpieces, modern works, and iconic collections in a landmark downtown building.
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Journey information
Overview: Greenville, SC to Chicago, IL flight
USAUSA
Flights from Greenville, SC to Chicago, IL depart on average 38 times per day, taking around 2h 19m. Cheap flight tickets for this journey start at $145 (€117) but you can travel from only $129 (€104) by bus.
There are 2 flights per day. The earliest flight runs at 00:02, the last at 23:55. The fastest flight covers the 561 miles (903 km) distance in 2h 16m. November is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $129 (€104)
Distance 561 miles (903 km) |
Average flight duration 2h 19m |
Cheapest ticket price $145 (€117) |
Flights per day 38 |
Direct flights 2 |
Fastest flight 2h 16m |
First flight 12:02 AM |
Last flight 11:55 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $129 (€104)
The cheapest and fastest flights from Greenville, SC to Chicago, IL
Showing times and prices for May 30
Cheapest price
$221
Average price
$221
Fastest journey
2 h 16 m
Average duration
2 h 16 m
Flights per day
1
Distance
903 km
Cheap tickets
The best way to find a cheap flight ticket from Greenville, SC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Chicago, IL will cost around $221 if you buy it on the day, but the cheapest tickets can be found for only $221.
Fast flights
Of the 1 flights that leave Greenville, SC for Chicago, IL onSat, May 30, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, May 30 the direct flights cover the 903 km distance in an average of 2 h 16 m but if you time it right, some flights will get you there in just 2 h 16 m .
On Sat, May 30 the longest flights will take 2 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:29 PM2h16Greenville, SC2:45 PMChicago, IL$2211One-way0 transfers
- 12:29 PM2h16Greenville, SC2:45 PMChicago, IL$2211One-way0 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $129. For those with little time consider booking a flight which can get you there in 2h 19m. The ticket price range depends on the travel mode: a bus costs an average of $129, and a flight costs an average of $145.
Distance: 561 miles (903 km)
Compare flight with
| Flight | Most popular Bus | Train | Driving |
|---|---|---|---|
$293 Average price | $195 Average price Cheapest | $285 Average price | $138 Average price (fuel + tolls) |
5h 19m Average total duration Fastest 2h 19m Onboard + 3h 0m Additional time* | 19h 10m Average total duration 18h 40m Onboard + 30m Additional time* | 34h 9m Average total duration 33h 39m Onboard + 30m Additional time* | 10h 55m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Chicago, IL is a bus with an average price of $195 (€157).
This is compared to other travel options from Greenville, SC to Chicago, IL:
A bus is $90 (€72) less than a train for this route with tickets for a train from Greenville, SC to Chicago, IL costing on average $285 (€230).
A bus is $98 (€79) less than a flight for this route with tickets for a flight from Greenville, SC to Chicago, IL costing on average $293 (€236).
The fastest way to travel from Greenville, SC to Chicago, IL is by flight with an average journey time of 2h 19m.
Other travel options to Chicago, IL take longer:
Bus takes on average 18h 40m.
Train takes on average 33h 39m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Chicago, IL including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Greenville, SC to Chicago, IL among Omio's users.
Live departures
Greenville, SC to Chicago, IL flight times
The table below shows live departures for Greenville, SC to Chicago, IL flights for tomorrow, Saturday, May 30. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:29 PM Greenville, SC | 2h16 | 2:45 PM Chicago, IL | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Complete guide to Chicago
Things to do in Chicago
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
- Must visit
Field Museum
A world-class natural history museum famous for its dinosaur fossils, ancient cultures, and major scientific collections, including the celebrated T. rex specimen SUE.
- Must visit
Museum Of Science And Industry
A large interactive science museum in Hyde Park with hands-on exhibits, transportation displays, and family-friendly experiences in a grand historic building.
- Must visit
Millennium Park
Chicago’s signature downtown park combines major public art, gardens, and event spaces, making it one of the city’s essential first stops for visitors.
- Must visit
The Magnificent Mile
The city’s best-known stretch of Michigan Avenue is lined with landmark buildings, shops, and hotels, and serves as a central walking route for first-time visitors.
- Must visit
Chicago Riverwalk
A highly popular waterfront promenade with excellent architecture views, bridges, and easy access to boat tours. It is one of the city’s most scenic urban walks.
Deep-Dish Pizza
Chicago’s iconic thick, buttery-crust pizza baked in a deep pan with layers of cheese, toppings, and chunky tomato sauce.
Chicago-Style Hot Dog
An all-beef hot dog on a poppy seed bun topped with mustard, onions, relish, tomato, pickle spear, sport peppers, and celery salt.
Italian Beef Sandwich
Thin-sliced seasoned roast beef served on a long roll, often dipped in jus and topped with sweet peppers or giardiniera.
Girl & the Goat
A celebrated West Loop restaurant with bold small plates, creative flavors, and a vibrant, modern atmosphere.
Alinea
Chicago’s internationally renowned fine-dining destination known for highly creative tasting menus and theatrical presentation.
Lou Malnati's Pizzeria
A classic Chicago pizzeria famous for buttery-crust deep-dish pizza and a relaxed, family-friendly atmosphere.
United States Dollar
Moderate for a major U.S. city: casual food is reasonable, but hotels, parking, and fine dining add up fast.
Average meal costs
- Budget
- USD 10-18 for fast food or casual takeout.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 80+ per person before drinks and tip.
- Coffee
- USD 4-7 for a coffee drink.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotels: USD 2-5 for housekeeping; USD 1-2 per bag.
FAQs: Greenville, SC to Chicago, IL Flight
Find answers to the most common questions about traveling from Greenville, SC to Chicago, IL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Greenville, SC to Chicago, IL can start from as little as $145 (€117) when you book in advance. The average flight ticket price for Greenville, SC to Chicago, IL is $293 (€236) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Greenville, SC to Chicago, IL is 2h 16m to travel the 561 miles (903 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Greenville, SC to Chicago, IL leaves at 12:02 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Greenville, SC to Chicago, IL leaves at 11:55 PM.
The cheapest month for a flight from Greenville, SC to Chicago, IL is November.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Chicago, IL including taking a bus, train, and flight.
Since neither Greenville, SC nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between Greenville, SC and Chicago, IL all year round.
The best events to attend in Chicago, IL include:
- Chicago Air and Water Show, an exhilarating display of military and civilian aircraft performing daring maneuvers over Lake Michigan
- Lollapalooza, a massive music festival featuring top artists across multiple genres in Grant Park
- Chicago Gourmet, a premier culinary event celebrating the city's vibrant food scene with tastings, cooking demonstrations, and wine pairings.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best holidays to experience in Chicago, IL include:
- Memorial Day, the unofficial start of summer with vibrant outdoor activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a lively atmosphere with various festivals and pleasant weather.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
The best season to visit Chicago, IL is Spring or Summer. The best weather to explore Chicago, IL is during May-September.
We recommend using the bus as it is the most popular way to get from Greenville, SC to Chicago, IL among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from Greenville, SC to Chicago, IL
Greenville
Chicago
The major airport for departures in Greenville is Greenville-Spartanburg International Airport. Find all the information you need to know about services, amenities and connections at Greenville-Spartanburg International Airport for your trip from Greenville to Chicago.
Greenville-Spartanburg International Airport (GSP)
information
The major airport for arrivals in Chicago is O'Hare International Airport. Find all the information you need to know about services, amenities and connections at O'Hare International Airport for your journey to Chicago from Greenville.
Amenities at airport
Wifi
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Car Rentalinformation
Distance to city center
3 km
Car connection
I-190, Exit 1Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops are located in all terminals, including duty-free and brands like Hudson and MAC Cosmetics.
Parking
- Parking available with options including hourly, daily, and economy lots, approximately 2.85€ ($3) per hour.
Dining
- Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps, toilets
WC
- Available throughout the airport.
Hotel
- Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby.
Shower
- Showers are available in some lounges, such as the United Club, but access may require a fee or membership.
Lounge
- Lounges available, including United Club and American Airlines Admirals Club.
Lost and Found Office
- Lost and Found located in terminal 1, near the baggage claim area.
Car Rental
- Car rental services are available at the Multi-Modal Facility, with companies like Hertz and Avis.
Public transit options for O'Hare International Airport
- CTA Blue Line, O'Hare Station, 45 minutes to city center
Most popular flights from Greenville, SC
More options for your journey from Greenville, SC to Chicago, IL
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Most popular flights to and from Chicago, IL and Greenville, SC
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