Travel Information
Compare bus, train, and flight for Greenville, SC to Jacksonville, FL
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from €106. For those with little time consider booking a flight which can get you there in 4h 17m. The ticket price range depends on the travel mode: a bus costs an average of €106, and a flight costs an average of €260.
Distance: 315 miles (507 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€161 Average price | €108 Average price Cheapest | €260 Average price |
23h 59m Average total duration 23h 29m Onboard + 30m Additional time* | 11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 7h 17m Average total duration Fastest 4h 17m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Greenville to Jacksonville trains with Omio?
Amtrak operates all train services from Greenville to Jacksonville. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville to Jacksonville.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville to Jacksonville.
Journey information
Overview: Train from Greenville, SC to Jacksonville, FL
Trains from Greenville, SC to Jacksonville, FL run on average 2 times per day, taking around 23h 29m. Cheap train tickets for this journey start at $185 (€148) but you can travel from only $133 (€106) by bus.
The earliest train runs at 02:23, the last at 22:33. The fastest train covers the 315 miles (507 km) distance in 28h 9m.
Distance 315 miles (507 km) |
Average train duration 23h 29m |
Cheapest ticket price $185 (€148) |
Trains per day 2 |
Fastest train 28h 9m |
First train 02:23 |
Last train 22:33 |
Train companies: Amtrak from Greenville, SC to Jacksonville, FL trainsAmtrak trains will get you between Greenville, SC and Jacksonville, FL from $133 (€106). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Greenville, SC to Jacksonville, FL
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Greenville, SC to Jacksonville, FL
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available adjacent to the station, open 24/7.
- Soby's
- Larkin's on the River
- Outside the main entrance.
- Ramps, assistance.
- $1.00
- The Westin Poinsett, Greenville
- Courtyard Greenville Downtown
- Hyatt Regency Greenville
- Located in the main hall
- Located in the main hall
- Free
- The station has a single platform for Amtrak services and a waiting area.
- Bus: Greenlink Transit Route 3
- Taxi services available
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Several lines available
Most popular train connections from Greenville, SC
More options for your journey from Greenville, SC to Jacksonville, FL
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