The cheapest and fastest trains from Greenville, SC to Jacksonville, FL
Cheapest price
$213
Average price
$213
Fastest journey
1 d 4 h 9 m
Average duration
1 d 4 h 9 m
Trains per day
1
Distance
507 km
The best way to find a cheap train ticket from Greenville, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Jacksonville, FL will cost around $213 if you buy it on the day, but the cheapest tickets can be found for only $213.
Of the 1 trains that leave Greenville, SC for Jacksonville, FL on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 507 km distance in an average of 1 d 4 h 9 m but if you time it right, some trains will get you there in just 1 d 4 h 9 m .
On Fri, Nov 07 the slowest trains will take 1 d 4 h 9 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greenville, SC to Jacksonville, FL
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from €106. For those with little time consider booking a flight which can get you there in 4h 17m. The ticket price range depends on the travel mode: a bus costs an average of €106, and a flight costs an average of €260.
Distance: 315 miles (507 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€161 Average price | €108 Average price Cheapest | €260 Average price |
23h 59m Average total duration 23h 29m Onboard + 30m Additional time* | 11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 7h 17m Average total duration Fastest 4h 17m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Greenville, SC to Jacksonville, FL train times
The table below shows live departures for Greenville, SC to Jacksonville, FL trains for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:23 AM Greenville, SC | 28h09 | 10:32 AM Jacksonville, FL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
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Nov 13
Journey information
Overview: Train from Greenville, SC to Jacksonville, FL
Trains from Greenville, SC to Jacksonville, FL run on average 2 times per day, taking around 23h 29m. Cheap train tickets for this journey start at $182 (€148) but you can travel from only $131 (€106) by bus.
The earliest train runs at 02:23, the last at 22:33. The fastest train covers the 315 miles (507 km) distance in 28h 9m.
Distance 315 miles (507 km) |
Average train duration 23h 29m |
Cheapest ticket price $182 (€148) |
Trains per day 2 |
Fastest train 28h 9m |
First train 02:23 |
Last train 22:33 |
Train companies: Amtrak from Greenville, SC to Jacksonville, FL trainsAmtrak trains will get you between Greenville, SC and Jacksonville, FL from $131 (€106). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Greenville, SC to Jacksonville, FL
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Greenville, SC to Jacksonville, FL
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available adjacent to the station, open 24/7.
- Soby's
- Larkin's on the River
- Outside the main entrance.
- Ramps, assistance.
- $1.00
- The Westin Poinsett, Greenville
- Courtyard Greenville Downtown
- Hyatt Regency Greenville
- Located in the main hall
- Located in the main hall
- Free
- The station has a single platform for Amtrak services and a waiting area.
- Bus: Greenlink Transit Route 3
- Taxi services available
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Several lines available
Most popular train connections from Greenville, SC
More options for your journey from Greenville, SC to Jacksonville, FL
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