- Must visit
Cummer Museum of Art & Gardens
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Cheapest price
$180
Average price
$180
Fastest journey
1 d 4 h 9 m
Average duration
1 d 4 h 9 m
Trains per day
1
Distance
507 km
The best way to find a cheap train ticket from Greenville, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Jacksonville, FL will cost around $180 if you buy it on the day, but the cheapest tickets can be found for only $180.
Of the 1 trains that leave Greenville, SC for Jacksonville, FL on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct trains cover the 507 km distance in an average of 1 d 4 h 9 m but if you time it right, some trains will get you there in just 1 d 4 h 9 m .
On Wed, Aug 05 the slowest trains will take 1 d 4 h 9 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Trains from Greenville, SC to Jacksonville, FL run on average 3 times per day, taking around 23h 29m. Cheap train tickets for this journey start at $122 but you can travel from only $88 by bus.
The earliest train runs at 02:23, the last at 22:33. The fastest train covers the 315 miles (507 km) distance in 28h 9m.
Distance 315 miles (507 km) |
Average train duration 23h 29m |
Cheapest ticket price $122 |
Trains per day 3 |
Fastest train 28h 9m |
First train 2:23 AM |
Last train 10:33 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 14 days |
The table below shows live departures for Greenville, SC to Jacksonville, FL trains for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:23 AM Greenville, SC | 28h09 | 10:32 AM Jacksonville, FL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Jacksonville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville, FL trip today.
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Regional history museum covering Northeast Florida through engaging exhibits on city growth, culture, and key local events.
Contemporary art museum in the university district, presenting rotating exhibitions and thoughtful programs by living artists.
Lively riverfront district with museums, restaurants nearby, public art, and one of Jacksonville's best skyline strolls.
Scenic promenade across the river from downtown, ideal for walks, bridge views, and sunset photos along the Southbank.
Creative historic neighborhood known for murals, local shops, nightlife, and a walkable mix of old Jacksonville character.
Mayport shrimp are local Atlantic shrimp, prized for their sweet flavor. They are a Jacksonville seafood staple, often served fried, grilled, or in baskets near the coast.
A Low Country boil with shrimp, sausage, corn, and potatoes reflects Northeast Florida’s coastal Southern cooking and is popular at casual local seafood spots.
Fresh local oysters from nearby Florida waters are served raw, baked, or chargrilled. They are a classic Jacksonville choice tied to the region’s seafood culture.
Popular casual seafood restaurant in Mayport, best known for fresh local shrimp, fried seafood platters, and a laid-back dockside feel.
Refined riverfront steakhouse known for prime steaks, seafood, and polished service in an upscale setting on the Southbank.
Established upscale seafood restaurant with an extensive wine list, elegant atmosphere, and strong reputation for fresh fish and fine dining.
Moderate for US beach cities. Hotels vary by season; meals and coffee are typical US prices, and most visitors need a car as transit is limited.
Tip 18-20% at restaurants, more for great service. Taxis usually get 10-15%. Cafes often use tip jars or screens; $1-2 is common.
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Jacksonville, FL trains use the Greenville Station to Jacksonville Station station pair. Use this guide to compare Greenville, SC and Jacksonville, FL train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Greenville Station is 1 km from Greenville city centre. Public transport options include:
Greenville Station has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Soby's, Larkin's on the River
Free.
Ticket office support is available at Greenville Station. Information desks are located in the main hall.
Luggage storage is available at Greenville Station. Lost and found is available at the station.
Available at Greenville Station: Parking, Taxis, WC.
Available at Greenville Station: Bike Parking, Bike Rental.
Accessibility facilities are available at Greenville Station: Ramps, assistance.
Nearby hotels include The Westin Poinsett, Greenville, Courtyard Greenville Downtown, Hyatt Regency Greenville.
Jacksonville Station is 7 km from Jacksonville city centre. Public transport options include:
Jacksonville Station has practical services for this route, including Parking, Taxis, Accessibility, WC, Ticket Office, Information Desk, and Luggage Carts.
Ticket office support is available at Jacksonville Station. Information desks are located in the main hall.
Available at Jacksonville Station: Parking, Taxis, WC.
Accessibility facilities are available at Jacksonville Station: Ramps, restrooms.
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