Journey information
Overview: Greenville, SC to Jacksonville, FL flight
Flights from Greenville, SC to Jacksonville, FL depart on average 16 times per day, taking around 5h 16m. Cheap flight tickets for this journey start at $149 (€121) but you can travel from only $88 (€71) by bus.
The earliest flight runs at 05:00, the last at 20:37. The fastest flight covers the 315 miles (507 km) distance in 4h 33m. December is the cheapest month to fly.
Distance 315 miles (507 km) |
Average flight duration 5h 16m |
Cheapest ticket price $149 (€121) |
Flights per day 16 |
Fastest flight 4h 33m |
Cheapest month December |
First flight 05:00 |
Last flight 20:37 |
The cheapest and fastest flights from Greenville, SC to Jacksonville, FL
Cheapest price
$298
Average price
$298
Fastest journey
5 h 56 m
Average duration
5 h 56 m
Flights per day
1
Distance
507 km
The best way to find a cheap flight ticket from Greenville, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Jacksonville, FL will cost around $298 if you buy it on the day, but the cheapest tickets can be found for only $298.
Of the 1 flights that leave Greenville, SC for Jacksonville, FL onMon, Mar 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct flights cover the 507 km distance in an average of 5 h 56 m but if you time it right, some flights will get you there in just 5 h 56 m .
On Mon, Mar 23 the longest flights will take 5 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greenville, SC to Jacksonville, FL
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $88. For those with little time consider booking a flight which can get you there in 5h 16m. The ticket price range depends on the travel mode: a bus costs an average of $88, and a flight costs an average of $149.
Distance: 315 miles (507 km)
Compare flight with
| Flight | Most popular Bus | Train |
|---|---|---|
$273 Average price | $157 Average price Cheapest | $174 Average price |
8h 16m Average total duration Fastest 5h 16m Onboard + 3h 0m Additional time* | 11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 23h 59m Average total duration 23h 29m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
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Mar 29
FAQs: Greenville, SC to Jacksonville, FL Flight
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

- Jacksonville Jazz Festival, a vibrant celebration of jazz music featuring top artists and local talent
- Jacksonville Sea & Sky Spectacular, an exciting air and sea show showcasing military and civilian aircraft along with thrilling boat displays
- One Spark, a unique crowdfunding festival that brings together creators, innovators, and entrepreneurs to showcase their projects.
- Memorial Day, the unofficial start of summer with vibrant beach activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, warm weather perfect for outdoor activities and fewer crowds.
popular airports
Popular airports from Greenville, SC to Jacksonville, FL
- Free Wi-Fi available throughout the airport.
- Shops available in the main terminal, including newsstands and gift shops.
- Parking available near the terminal, approximately 1.1€ (20 MXN) per hour.
- Restaurants available in Concourse A and C, including fast food and sit-down options like Chili's and Vino Volo.
- Available outside the terminal.
- Elevators, toilets
- Available throughout the airport, near gates and baggage claim.
- Hotels nearby, such as DoubleTree by Hilton, within walking distance.
- Showers available in some lounges, check access requirements.
- Lounges available, including Delta Sky Club, with access for eligible passengers.
- Lost and Found located in the main terminal, near baggage claim.
- Car rental services available on-site, with major companies like Hertz and Avis.
- Bus Route 1, JTA stop at Airport terminal, 13 miles
Most popular flights from Greenville, SC
More options for your journey from Greenville, SC to Jacksonville, FL
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