How to travel from Detroit, MI to St. Louis, MO

Thu, Sep 12
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Travel Information from Detroit, MI to St. Louis, MO

distanceDistance453 miles (731 km)
modeAvailable travel modesBus, train or flight
priceTicket price range$63 - $174
cheapestCheapest modeBus • $63 (€54) • 13 h 40 min
fastestFastest modeFlight • $174 (€150) • 4 h 28 min
carriersPopular travel companiesGreyhound, Sky West Airlines or Amtrak

Travel 453 miles (731 km) by bus, train or flight to St. Louis, MO from Detroit, MI. The most popular travel companies which serve this trip are Greyhound, Sky West Airlines or Amtrak among others. Travelers can even take a direct bus, flight or train from Detroit, MI to St. Louis, MO.

Travel options
from Detroit, MI to St. Louis, MO

How to get from Detroit, MI to St. Louis, MO by train, bus or flight.

Our recommendation
bus

The best way to travel from Detroit, MI to St. Louis, MO is by taking a bus because it’s the best combination of price and speed.

FlixBus
01:45PM15h00
Detroit, MI
04:45AMSt. Louis, MO
$891One-way
0 transfers
Cheapest
FlixBus
01:45PM15h00
Detroit, MI
04:45AMSt. Louis, MO
$891One-way
0 transfers
Fastest
FlixBus
01:45PM15h00
Detroit, MI
04:45AMSt. Louis, MO
$891One-way
0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Fri
Sep 13
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Sep 19

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SNCF

All travel companies: Airlines, Train and Bus from Detroit to St. Louis

Travel between Detroit and St. Louis on Amtrak, American Airlines and Greyhound travel with Omio. When comparing schedules and tickets, we will also show you other options with multiple connections or other travel modes if they’re available.

Amtrak is a passenger train service based in the United States. It operates more than 300 trains daily including trains from Detroit to St. Louis, connecting more than 500 destinations in 46 states and three Canadian provinces. Amtrak offers a variety of train types, including the Acela Express, Northeast Regional, Keystone Service, and the Auto Train. The Acela Express is the fastest train, reaching speeds of up to 150 mph. The Northeast Regional is the most popular, offering frequent service between major cities in the Northeast. The Keystone Service is a regional service connecting Philadelphia and Harrisburg, Pennsylvania. The Auto Train is a unique service that allows passengers to transport their cars along with them. Amtrak offers a variety of ticket types, including Saver, Value, Flexible, and Business Class. Saver tickets are the most affordable, while Business Class tickets offer the most amenities, such as complimentary meals and access to the Amtrak Metropolitan Lounge. Onboard facilities vary by train type, but all Amtrak trains offer comfortable seating, Wi-Fi, and power outlets. The most popular routes for Amtrak include the Northeast Corridor, which runs between Washington, D. C. And Boston, and the Pacific Surfliner, which runs between San Diego and San Luis Obispo, California. Other popular routes include the Capitol Corridor, which runs between San Jose and Sacramento, California, and the Empire Builder, which runs between Chicago and Seattle.

      American Airlines is one of the leading airlines in the USA and the world; they offer Main Cabin, Business and First Class tickets for your travel to St. Louis from Detroit.

        FAQs: Travel from Detroit, MI to St. Louis, MO

        FAQs: Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Detroit, MI to St. Louis, MO.
        FAQs

        There are 3 options to travel from Detroit, MI to St. Louis, MO including taking a bus, train or flight.

        The cheapest way to travel between Detroit, MI and St. Louis, MO is a bus with an average price of $63 (€54).

        This is compared to other travel options from Detroit, MI to St. Louis, MO:

        A bus is $111 (€96) less than a flight with an average ticket price of $174 (€150) from Detroit, MI to St. Louis, MO.

        A bus is $17 (€14) less than a train for this trip with tickets for a train from Detroit, MI to St. Louis, MO costing on average $79 (€68).

        The fastest way to get to St. Louis, MO from Detroit, MI is by flight with an average travel time of 4 h 28 min.

        Other travel options to St. Louis, MO take longer:

        Bus takes 13 h 40 min on average.

        Train takes 13 h 41 min on average.

        You should expect to travel around 453 miles (731 km) between Detroit, MI and St. Louis, MO.

        The average frequency per day from Detroit, MI to St. Louis, MO is:

          However, we recommend checking specific travel dates for your trip to St. Louis, MO from Detroit, MI as scheduled services by bus, train or flight can vary by season or day of the week.

          These are the most popular departure and arrival points when traveling from Detroit, MI to St. Louis, MO:

            Omio works with many trusted partners that can help you travel the best way from Detroit, MI to St. Louis, MO:

            • You can travel from Detroit, MI to St. Louis, MO by bus with Greyhound. You can find cheap tickets on Omio for $116 (€100) with Greyhound from Detroit, MI to St. Louis, MO.
            • You can travel by plane from Detroit, MI to St. Louis, MO with Sky West Airlines or American Airlines, and you can find American Airlines Detroit, MI to St. Louis, MO tickets for $251 (€216) on Omio.
            • You can take a train from Detroit, MI to St. Louis, MO with Amtrak. Cheap tickets can be found for $106 (€92) with Amtrak from Detroit, MI to St. Louis, MO.

            Yes, there are direct services available from Detroit, MI to St. Louis, MO with the following travel companies:

            • Direct services by bus with.
            • Direct services by plane with.
            • Direct services by train with.

            Direct services tend to save you time and add more convenience in getting you to St. Louis, MO as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between Detroit, MI and St. Louis, MO.

            Looking to extend your trip from Detroit, MI to St. Louis, MO? Many Omio customers who go from Detroit, MI to St. Louis, MO usually extend their vacation to explore other popular destinations like Chicago, IL, Jefferson City, MO, Kansas City, KS, Joliet, IL or Rolla, MO. If you're looking to explore Chicago, IL, Jefferson City, MO, Kansas City, KS, Joliet, IL or Rolla, MO from St. Louis, MO, let Omio find you the best connections available at an affordable price.
            HomeTravelTravel to USATravel to St. Louis, MOHow to travel from Detroit, MI to St. Louis, MO

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