How to travel from Detroit, MI to St. Louis, MO

Thu, Dec 11
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Miller Transportation
1,000+ more
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Travel Information between Detroit, MI and St. Louis, MO

Distance453 miles (731 km)
Available travel modesBus, train or flight
Ticket price range$60 - $116
Cheapest modeBus • $60 (€54) • 15 h
Fastest modeFlight • $116 (€105) • 4 h 33 min
Popular travel companiesGreyhound, American Airlines or Amtrak

Travel 453 miles (731 km) by bus, train or flight between Detroit, MI and St. Louis, MO. The most popular travel companies which serve this trip are Greyhound, American Airlines or Amtrak among others. Travelers can even take a direct bus, flight or train from Detroit, MI to St. Louis, MO.

Travel options
from Detroit, MI to St. Louis, MO

How to get from Detroit, MI to St. Louis, MO by train, bus or flight.

Our recommendation

bus

The best way to travel from Detroit, MI to St. Louis, MO is by taking a bus because it’s the best combination of price and speed.

Greyhound
12:35PM16h00
Detroit, MI
04:35AMSt. Louis, MO
$1511One-way
0 transfers

Cheapest

Greyhound
12:35PM16h00
Detroit, MI
04:35AMSt. Louis, MO
$1511One-way
0 transfers

Fastest

FlixBus
08:20PM15h05
Detroit, MI
11:25AMSt. Louis, MO
$2081One-way
0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Detroit, MI to St. Louis, MO

Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Detroit, MI to St. Louis, MO.

FAQs

There are 3 options to travel to St. Louis, MO from Detroit, MI including taking a bus, train or flight.

The cheapest way to get from Detroit, MI to St. Louis, MO is by taking a bus with average ticket prices of $60 (€54) compared to other travel options to St. Louis, MO:

Taking a bus costs $55 (€50) less than taking a flight, which costs on average $116 (€105) for the same trip.

A bus is $25 (€23) less than a train for this route with tickets for a train from Detroit, MI to St. Louis, MO costing on average $86 (€77).

The fastest way to get to St. Louis, MO from Detroit, MI is by flight with an average travel time of 4 h 33 min.

Other travel options to St. Louis, MO take longer:

Getting to St. Louis, MO by bus takes 15 h on average.

Taking a train requires on average 13 h 41 min of travel time.

The distance from Detroit, MI to St. Louis, MO is approximately 453 miles (731 km).

The average frequency per day from Detroit, MI to St. Louis, MO is:

  • 3 buses a day.
  • Around 16 flights per day.
  • 2 trains per day.

However, we recommend checking specific travel dates for your trip to St. Louis, MO from Detroit, MI as scheduled services by bus, train or flight can vary by season or day of the week.

These are the most popular departure and arrival points when traveling from Detroit, MI to St. Louis, MO:

    Omio works with many trusted partners that can help you travel the best way from Detroit, MI to St. Louis, MO:

    • You can take a bus from Detroit, MI to St. Louis, MO with Greyhound. Cheap tickets can be found for $73 (€66) with Greyhound from Detroit, MI to St. Louis, MO.
    • You can take a flight from Detroit, MI to St. Louis, MO with American Airlines. Cheap tickets can be found for $116 (€105) with American Airlines from Detroit, MI to St. Louis, MO.
    • You can travel to St. Louis, MO from Detroit, MI by train with Amtrak. You can find cheap tickets on Omio for $86 (€77) with Amtrak from Detroit, MI to St. Louis, MO.

    Yes, there are direct routes from Detroit, MI to St. Louis, MO with the following travel companies:

    • You'll find direct buses with.
    • You can book a direct flight with.
    • You can travel directly by train with.

    Direct services to St. Louis, MO tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your route.

    Many of our customers who book a trip from Detroit, MI to St. Louis, MO often extend their vacation and travel to other popular destinations like Chicago, IL, Jefferson City, MO, Kansas City, KS, Joliet, IL or Rolla, MO. If you’re thinking of adding another destination to your Detroit, MI and St. Louis, MO itinerary, let Omio find you the best connections between St. Louis, MO and any of these top destinations today!
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