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Travel Information
Compare bus, train, and flight for Detroit, MI to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Detroit, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $87. For those with little time consider booking a flight which can get you there in 4h 52m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $87, and a flight costs an average of $198.
Distance: 454 miles (731 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$150 Average price Cheapest | $161 Average price | $384 Average price |
13h 46m Average total duration 13h 16m Onboard + 30m Additional time* | 10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 7h 52m Average total duration Fastest 4h 52m Onboard + 3h 0m Additional time* |
0.7 - 1.8kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.2 - 4.4kg CO2 emissions |
 Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Detroit, MI to St. Louis, MO
How to get from Detroit, MI to St. Louis, MO by train, bus or flight.
Our recommendation
The best way to travel from Detroit, MI to St. Louis, MO is by taking a bus because it’s the best combination of price and speed.
- +
FlixBus8:20 AM16h00Detroit, Greyhound Terminal11:20 PMSt. Louis, S 15th St (Civic center)$1291One-way1 transfer
Cheapest
- +FlixBus11:15 PM17h25Detroit, Greyhound Terminal3:40 PMSt. Louis, S 15th St (Civic center)$1201One-way1 transfer
Fastest
AA1259+
AA38706:00 AM3h27Detroit Wayne County Airport8:27 AMSt. Louis Lambert International Airport$5321One-way1 transfer
Other options
- 353 Wolverine · 305 Lincoln Service9:35 AM13h48Detroit Amtrak, Detroit, MI10:23 PMSt. Louis Station, St. Louis, MO$1421One-way1 transfer
- 351 Wolverine · 21 Texas Eagle7:03 AM13h22Detroit Amtrak, Detroit, MI7:25 PMSt. Louis Station, St. Louis, MO$1551One-way1 transfer
- undefined · undefined8:15 PM12h40Detroit, Greyhound Terminal7:55 AMSt. Louis, S 15th St (Civic center)$1301One-way1 transfer
- +FlixBus4:20 PM15h05Detroit, Greyhound Terminal6:25 AMSt. Louis, S 15th St (Civic center)$1291One-way1 transfer
AA5013+AA19268:20 AM4h27Detroit Wayne County Airport11:47 AMSt. Louis Lambert International Airport$5321One-way1 transfer- AA1439 · AA29587:20 AM7h02Detroit Wayne County Airport1:22 PMSt. Louis Lambert International Airport$5321One-way1 transfer
- AA2054 · AA24773:30 PM5h00Detroit Wayne County Airport7:30 PMSt. Louis Lambert International Airport$5321One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Detroit, MI to St. Louis, MO
Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Detroit, MI to St. Louis, MO.
This is compared to other travel options from Detroit, MI to St. Louis, MO:
A bus is $5 (€4) less than a train for this route with tickets for a train from Detroit, MI to St. Louis, MO costing on average $92 (€74).
A bus is $110 (€88) less than a flight for this route with tickets for a flight from Detroit, MI to St. Louis, MO costing on average $198 (€158).
Other travel options to St. Louis, MO take longer:
Train takes on average 13h 41m.
Bus takes on average 12h 40m.
- Around 32 flights per day.
- Around 3 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Detroit, MI and St. Louis, MO as scheduled services by bus, train, and flight can vary by season or day of the week.
- Buses mostly depart from Detroit, Greyhound Terminal and arrive in St. Louis, S 15th St (Civic center).
- Trains mostly depart from Detroit Amtrak, Detroit, MI and arrive in St. Louis Station, St. Louis, MO.
- Flights mostly depart from Detroit Wayne County Airport and arrive in St. Louis Lambert International Airport.
- Travel with Amtrak to go to St. Louis, MO by train.
- Travel with United to go to St. Louis, MO by flight.
- Travel with Greyhound, FlixBus, Barons Bus, Miller Transportation to go to St. Louis, MO by bus.
Travelling from Detroit, MI to St. Louis, MO: related information
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