The cheapest and fastest trains from Detroit, MI to St. Louis, MO
Cheapest price
$128
Average price
$128
Fastest journey
13 h 41 m
Average duration
13 h 41 m
Trains per day
1
Distance
731 km
The best way to find a cheap train ticket from Detroit, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to St. Louis, MO will cost around $128 if you buy it on the day, but the cheapest tickets can be found for only $128.
Of the 1 trains that leave Detroit, MI for St. Louis, MO on Fri, Nov 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 28 the direct trains cover the 731 km distance in an average of 13 h 41 m but if you time it right, some trains will get you there in just 13 h 41 m .
On Fri, Nov 28 the slowest trains will take 13 h 41 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Detroit, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Detroit, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €56. For those with little time consider booking a flight which can get you there in 4h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of €56, and a flight costs an average of €26.
Distance: 454 miles (731 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€118 Average price | €86 Average price Cheapest | €212 Average price |
11h 0m Average total duration 10h 30m Onboard + 30m Additional time* | 13h 35m Average total duration 13h 5m Onboard + 30m Additional time* | 7h 43m Average total duration Fastest 4h 43m Onboard + 3h 0m Additional time* |
0.2 - 0.7kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | 2.2 - 4.4kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Detroit, MI to St. Louis, MO train times
The table below shows live departures for Detroit, MI to St. Louis, MO trains for tomorrow, Friday, November 28. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:26 AM Detroit, MI | 13h41 | 12:07 AM St. Louis, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Detroit, MI to St. Louis, MO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Dec 04
Why should you book Detroit to St. Louis trains with Omio?
Amtrak operates all train services from Detroit to St. Louis. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Detroit to St. Louis.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Detroit to St. Louis.
Journey information
Overview: Train from Detroit, MI to St. Louis, MO
Trains from Detroit, MI to St. Louis, MO run on average 2 times per day, taking around 10h 30m. Cheap train tickets for this journey start at $85 (€69) but you can travel from only $32 (€26) by flight.
The earliest train runs at 04:30, the last at 10:25. The fastest train covers the 454 miles (731 km) distance in 13h 41m.
Distance 454 miles (731 km) |
Average train duration 10h 30m |
Cheapest ticket price $85 (€69) |
Trains per day 2 |
Fastest train 13h 41m |
First train 04:30 |
Last train 10:25 |
Train companies: Amtrak from Detroit, MI to St. Louis, MO trainsAmtrak trains will get you between Detroit, MI and St. Louis, MO from $32 (€26). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Detroit, MI to St. Louis, MO
Find answers to the most common questions about traveling from Detroit, MI to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Detroit, MI to St. Louis, MO
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available adjacent to the station.
- Cuisine Restaurant
- New Center Eatery
- Outside the main entrance.
- Elevators, ramps.
- $1
- Hotel St. Regis
- The Inn on Ferry Street
- MotorCity Casino Hotel
- Located in the main hall
- Located in the main hall
- Free
- The station has a main hall with ticketing and waiting areas
- platforms are accessible via the main entrance.
- QLine streetcar
- Bus: Several lines available
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
More options for your journey from Detroit, MI to St. Louis, MO
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