The cheapest and fastest buses from Des Moines, IA to Columbus, OH
Cheapest price
$162
Average price
$162
Fastest journey
18 h 20 m
Average duration
1 d 2 h 13 m
Buses per day
2
Distance
911 km
The best way to find a cheap bus ticket from Des Moines, IA to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Columbus, OH will cost around $162 if you buy it on the day, but the cheapest tickets can be found for only $162.
It's difficult to get from Des Moines, IA to Columbus, OH without transferring at least once.




Travel Information
Compare bus and flight for Des Moines, IA to Columbus, OH
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Columbus, OH among Omio's users. If you are prioritising price take the bus with prices starting from $214. For those with little time consider booking a flight which can get you there in 4h 15m. The ticket price range depends on the travel mode: a bus costs an average of $214, and a flight costs an average of $412.
Distance: 566 miles (911 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$241 Average price Cheapest | $412 Average price |
21h 57m Average total duration 21h 27m Onboard + 30m Additional time* | 7h 15m Average total duration Fastest 4h 15m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Des Moines, IA to Columbus, OH bus times
The table below shows live departures for Des Moines, IA to Columbus, OH buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:20 AM Des Moines, IA | 18h20 | 3:40 AM Columbus, OH | 1 transfer | |
![]() | 9:45 AM Des Moines, IA | 34h05 | 7:50 PM Columbus, OH | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Columbus, OH by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Des Moines, IA to Columbus, OH buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Columbus, OH.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Columbus, OH.
Journey information
Overview: Bus from Des Moines, IA to Columbus, OH
Buses from Des Moines, IA to Columbus, OH run on average 4 times per day, taking around 21h 27m. Cheap bus tickets for this journey start at $214 (€174) if you book in advance.
The earliest bus runs at 03:45, the last at 23:30. The fastest bus covers the 566 miles (911 km) distance in 18h 5m.
Distance 566 miles (911 km) |
Average bus duration 21h 27m |
Cheapest ticket price $214 (€174) |
Buses per day 4 |
Fastest bus 18h 5m |
First bus 03:45 |
Last bus 23:30 |
Cheapest month Nov |
Cheapest day Sun |
High season Jan - Mar |
Low season Jul - Sep |
Bus providers: Greyhound from Des Moines, IA to Columbus, OHYou can travel by bus between Des Moines, IA to Columbus, OH with Greyhound for as low as $214 (€174). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Des Moines, IA to Columbus, OH
Find answers to the most common questions about traveling from Des Moines, IA to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Columbus Zoo and Aquarium, a renowned zoo featuring diverse animal exhibits and conservation programs
- Franklin Park Conservatory and Botanical Gardens, a horticultural landmark with seasonal exhibitions and a stunning glasshouse
- Ohio Statehouse, a Greek Revival-style capitol building offering guided tours and historical insights
- Scioto Mile, a scenic urban oasis with parks, fountains, and trails along the Scioto River
- Wexner Center for the Arts, a contemporary art gallery showcasing innovative exhibitions and performances.
- COSI (Center of Science and Industry), an interactive science museum offering hands-on exhibits and educational programs
- Short North Arts District, a vibrant neighborhood known for its art galleries, boutiques, and dining options
- German Village, a historic area with charming brick streets, unique shops, and traditional German cuisine
- North Market, a bustling public market featuring diverse food vendors and local products
- Columbus Museum of Art, offering engaging exhibitions and a dynamic collection of American and European art.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Des Moines, IA to Columbus, OH
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Columbus, OH
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