- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Cheapest price
€76
Average price
€77
Fastest journey
17 h 20 m
Average duration
19 h 44 m
Buses per day
5
Distance
911 km
The best way to find a cheap bus ticket from Des Moines, IA to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Columbus, OH will cost around €77 if you buy it on the day, but the cheapest tickets can be found for only €76.
It's difficult to get from Des Moines, IA to Columbus, OH without transferring at least once.
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FlixBusOmio recommends booking the bus as it is the most popular option from Des Moines, IA to Columbus, OH among Omio's users. If you are prioritising price take the bus with prices starting from €202. For those with little time consider booking a flight which can get you there in 4h 15m. The ticket price range depends on the travel mode: a bus costs an average of €202, and a flight costs an average of €334.
Distance: 566 miles (911 km)
Most popular Bus | Flight | Driving |
|---|---|---|
€207 Average price Cheapest | €334 Average price | €103 Average price (fuel + tolls) |
23h 38m Average total duration 23h 8m Onboard + 30m Additional time* | 7h 15m Average total duration Fastest 4h 15m Onboard + 3h 0m Additional time* | 9h 36m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Columbus, OH:
A bus is €128 less than a flight for this route with tickets for a flight from Des Moines, IA to Columbus, OH costing on average €334.
Other travel options to Columbus, OH take longer:
Bus takes on average 23h 8m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:30AM | Arrival Time 12:35AM | Duration 18h05 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €78 |
Operator Greyhound USA | Departure Time 09:20AM | Arrival Time 03:40AM | Duration 18h20 | Departure days Everyday | Cheapest price €75 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 03:40AM | Duration 17h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price €76 |
Operator Greyhound USA | Departure Time 09:45AM | Arrival Time 07:50PM | Duration 34h05 | Departure days Mon | Cheapest price €131 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 05:10PM | Duration 23h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €76 |
The table below shows live departures for Des Moines, IA to Columbus, OH buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 5:30 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 18h05 | 12:35 AM Columbus, E Mound St (Akili Christian High School), OH | 2 transfers | |
· · | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 18h55 | 5:15 AM Columbus, E Mound St (Akili Christian High School), OH | 2 transfers | |
· | 4:20 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 20h30 | 1:50 PM Columbus, E Mound St (Akili Christian High School), OH | 1 transfer | |
· + FlixBus | 4:20 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 23h50 | 5:10 PM Columbus, E Town St (Bus Station), OH | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Columbus, OH run on average 4 times per day, taking around 23h 8m. Cheap bus tickets for this journey start at €202 if you book in advance.
The earliest bus runs at 03:45, the last at 23:50. The fastest bus covers the 566 miles (911 km) distance in 19h 5m.
Distance 566 miles (911 km) |
Average bus duration 23h 8m |
Cheapest ticket price €202 |
Buses per day 4 |
Fastest bus 19h 5m |
First bus 3:45 AM |
Last bus 11:50 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from Des Moines, IA to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Des Moines, IA to Columbus, OH buses use the to Columbus, E Town St (Bus Station) station pair. Use this guide to compare Des Moines, IA and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need