Columbus, OH CMH to St. Louis, MO STL flight with United

Mon, Sep 21
+ Add return
American Airlines
Republic Airlines
United
skywest airlines
psa airlines
2,000+ travel companies
American Airlines
Republic Airlines
United
skywest airlines
psa airlines
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Journey information

Overview: Columbus, OH to St. Louis, MO flight

USAUSA
USAUSA
Icon of flight

Flights from Columbus, OH to St. Louis, MO depart on average 46 times per day, taking around 4h 14m. Cheap flight tickets for this journey start at CHF221 but you can travel from only CHF41 by bus.

The earliest flight runs at 05:00, the last at 21:28. The fastest flight covers the 395 miles (637 km) distance in 2h 50m. December is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from CHF41
Distance
395 miles (637 km)
Average flight duration
4h 14m
Cheapest ticket price
CHF221
Flights per day
46
Fastest flight
2h 50m
First flight
5:00 AM
Last flight
9:28 PM
Cheapest Month
Dec
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from CHF41

The cheapest and fastest flights from Columbus, OH to St. Louis, MO

Showing times, prices and bookable tickets for Sep 21

Cheapest price on Sep 21

CHF105

Average ticket price on Sep 21

CHF208

Fastest journey on Sep 21

4 h 33 m

Average journey duration on Sep 21

5 h 3 m

Flights on Sep 21

2

Distance

637 km

Cheap tickets

The best way to find a cheap flight ticket from Columbus, OH to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Columbus, OH to St. Louis, MO will cost around CHF208 if you buy it on the day, but the cheapest tickets can be found for only CHF105.

Fast flights

On Mon, Sep 21, we found 2 flights from Columbus, OH to St. Louis, MO, including 2 direct services.

On Mon, Sep 21 the direct flights cover the 637 km distance in an average of 5 h 3 m but if you time it right, some flights will get you there in just 4 h 33 m .

On Mon, Sep 21 the longest flights will take 5 h 32 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • American Airlines
    11:33 PM5h32
    Columbus, OH
    5:05 AMSt. Louis, MO
    CHF1051One-way
    0 transfers
  • American Airlines
    9:02 AM4h33
    Columbus, OH
    1:35 PMSt. Louis, MO
    CHF3111One-way
    0 transfers

Travel Information

Compare bus and flight for Columbus, OH to St. Louis, MO

Omio recommends booking the bus as it is the most popular option from Columbus, OH to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF61 For those with little time, consider booking a flight, which has an average total journey time of 6h 14m. Average ticket prices depend on the travel mode: a bus costs an average of CHF61, while a flight costs an average of CHF565.

Distance: 395 miles (637 km)

Compare flight with

Flight
Most popular
Bus
Driving

CHF565

Average price

CHF61

Average price

Cheapest

CHF70

Average price

(fuel + tolls)

6h 14m

Average total duration

Fastest

4h 14m

Onboard

+

2h 0m

Additional time*

10h 55m

Average total duration

10h 25m

Onboard

+

30m

Additional time*

6h 16m

Average total duration

(door-to-door)

United

Most popular airline

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Columbus, OH to St. Louis, MO is a bus with an average price of CHF61.

This is compared to other travel options from Columbus, OH to St. Louis, MO:

A bus is CHF504 less than a flight for this route with tickets for a flight from Columbus, OH to St. Louis, MO costing on average CHF565.

The fastest way to travel from Columbus, OH to St. Louis, MO is by flight with an average journey time of 4h 14m.

Other travel options to St. Louis, MO take longer:

Bus takes on average 10h 25m.

It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.

Live departures

Columbus, OH to St. Louis, MO flight times

The table below shows live departures for Columbus, OH to St. Louis, MO flights for tomorrow, Monday, September 21. You can also manually refresh the results below to see updated flight journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
American Airlines9:02 AM Columbus, OH
4h33
1:35 PM St. Louis, MO0 transfersDirect

This is the last flight of the day.

Find all the dates and times for this journey

Compare prices and tickets Columbus, OH to St. Louis, MO by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25
Sat
Sep 26
Sun
Sep 27

Airlines: United, American Airlines, Republic Airlines, psa airlines, skywest airlines from Columbus, OH to St. Louis, MOFind the best flights between Columbus, OH to St. Louis, MO with Omio's travel partners United, American Airlines, Republic Airlines, psa airlines, skywest airlines from CHF41. We can find you the best deals, schedules and tickets when comparing and booking the best trip.

United

About
United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.
Luggage & cancellation policy
Average United Duration
2h 50m
Cheapest United Price
CHF256
United frequency
29 a day
Luggage included
Carry-on baggage allowance is 7kg total (2 pieces max. ) for both Choice and Flex fares on United Airlines and Virgin Australia flights.
Additional luggage
Excess baggage fees apply for additional checked luggage beyond the standard allowance.
Luggage storage
Both airlines provide checked baggage services for storing luggage during flights.
Cancellation Policy
Cancellation fees apply per person, per booking, with specific fees for different fare types.
Refund
Not applicable to flights; however, full refunds are available if flights are canceled by the airline.
Pregnant on board
Pregnant passengers are permitted to travel, with specific guidelines and medical certificates required after a certain gestational period.
Unaccompagned minor
Unaccompanied minors are permitted to travel, with specific age restrictions and services provided.
Amenities on board the airplane
Wifi
Food sold onboard
Meals and snacks are included on international flights operated by United Airlines and Virgin Australia.
Seat reservation
Seat selection may incur additional fees, depending on the fare type and airline.
Toilets
USB plugs
Accessibility
United Airlines and Virgin Australia offer services to and within Australia, providing accessible travel options for passengers with mobility needs.
Bikes
Both airlines permit bicycles onboard, with specific guidelines and fees.
Pets
United Airlines and Virgin Australia allow pets onboard, subject to specific policies and fees.

American Airlines

About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
2h 51m
Cheapest American Airlines Price
CHF221
American Airlines frequency
10 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.

skywest airlines

About
SkyWest Airlines is a major North American regional airline headquartered in St. George, Utah. It operates flights for larger carriers such as Alaska Airlines (as Alaska SkyWest), American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express). SkyWest is the largest regional airline in North America by fleet size, passengers carried, and destinations served. The airline connects passengers to over 250 destinations across the United States, Canada, and Mexico, primarily linking smaller airports to major airline hubs. SkyWest's fleet consists of regional jets, including the Bombardier CRJ series and Embraer 175 aircraft.
Luggage & cancellation policy
Average skywest airlines Duration
2h 52m
Cheapest skywest airlines Price
CHF224
skywest airlines frequency
2 a day
Luggage included
One carry-on bag and one personal item are allowed for free.
Additional luggage
Additional luggage can be purchased, and fees apply for excess, oversized, or overweight baggage.
Cancellation Policy
If canceled within 24 hours of purchase, a full refund is possible, provided the departure is at least 7 days away; after 24 hours, fees range from $100 to $500.
Refund
If SkyWest Airlines cancels a flight, passengers are eligible for a full refund.
Pregnant on board
Being pregnant on board is allowed, but specific policies may depend on the partner airline.
Unaccompagned minor
Children aged 5-14 can travel alone using the unaccompanied minor service, which includes airport escort and supervision.
Amenities on board the airplane
Seat reservation
Toilets
Accessibility
SkyWest Airlines complies with all provisions of the Air Carrier Access Act and accommodates customers with special needs.
Bikes
Bicycles can be checked in but may incur additional fees and must be properly packed.
Pets
Small pets like cats and dogs are allowed in the cabin for a fee, with restrictions on pet and carrier size.

psa airlines

About
PSA Airlines is an American regional airline and a wholly-owned subsidiary of the American Airlines Group, operating exclusively on behalf of American Airlines under the American Eagle brand. Headquartered in Charlotte, North Carolina, PSA Airlines operates over 800 daily flights to nearly 100 destinations across the United States. The airline maintains an all-jet fleet consisting of Bombardier CRJ700 and CRJ900 regional aircraft. With a team of over 5,000 employees, PSA Airlines plays a significant role in connecting smaller cities to major hubs within American Airlines' network.
Luggage & cancellation policy
Average psa airlines Duration
3h 57m
Cheapest psa airlines Price
CHF511
psa airlines frequency
1 a day
Luggage included
One carry-on bag and one personal item are allowed.
Additional luggage
Additional luggage can be checked for a fee, with weight limits up to 32kg (70lbs) for a single piece.
Cancellation Policy
PSA Airlines' cancellation policy depends on the timeframe of cancellation and ticket flexibility, with some flexible ticket options offering easier cancellations.
Refund
Passengers are entitled to a refund if the airline cancels a flight and they choose not to travel.
Amenities on board the airplane
Food sold onboard
Non-alcoholic beverages are complimentary in Economy Class, while alcoholic drinks and snack boxes can be purchased.
Seat reservation
Seat selection for standard seating is typically included, but preferred or Main Cabin Extra seats may require an additional fee.
Accessibility
Wheelchair assistance is available and should be requested at least 24 hours prior to flight departure.
Bikes
Bicycles can be carried as checked baggage if handlebars are turned sideways, pedals are removed, tires are deflated, and the bike is packed in a case or durable cardboard box.

Republic Airlines

About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Republic Airlines Duration
2h 53m
Cheapest Republic Airlines Price
CHF221
Republic Airlines frequency
4 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.

Complete guide to St. Louis, MO

Things to do in St. Louis, MO

Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.

  • Must visit

Saint Louis Art Museum

Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.

  • Recommended

Missouri History Museum

Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.

  • Recommended

Saint Louis Science Center

Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.

United States dollar ($)

Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.

Average meal costs

Budget
$10-15 for fast food or casual lunch.
Mid-range
$20-35 per person for a mid-range restaurant meal.
Fine dining
$60+ per person at upscale restaurants.
Coffee
$3-5 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.

FAQs: Columbus, OH to St. Louis, MO Flight

Find answers to the most common questions about traveling from Columbus, OH to St. Louis, MO by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Columbus, OH to St. Louis, MO can start from as little as CHF221 when you book in advance. The average flight ticket price for Columbus, OH to St. Louis, MO is CHF565 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Columbus, OH to St. Louis, MO is 2h 50m to travel the 395 miles (637 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Columbus, OH to St. Louis, MO leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Columbus, OH to St. Louis, MO leaves at 9:28 PM.
Flights from Columbus, OH to St. Louis, MO generally leave from John Glenn International Airport and arrive in St. Louis Lambert International Airport.John Glenn International Airport is 1 miles (2 km) away from Columbus, OH city centre and St. Louis Lambert International Airport is 1 miles (2 km) from St. Louis, MO city centre.
The cheapest month for a flight from Columbus, OH to St. Louis, MO is December.
It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
Since neither Columbus, OH nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between Columbus, OH and St. Louis, MO all year round.
The best events to attend in St. Louis, MO include:
  • St. Louis Mardi Gras, a vibrant celebration featuring parades, live music, and festive activities in the Soulard neighborhood
  • St. Louis Art Fair, an annual event showcasing local and national artists with art exhibits, live performances, and culinary delights
  • Fair St. Louis, a multi-day Independence Day festival with fireworks, concerts, and family-friendly activities along the Gateway Arch.
The best holidays to experience in St. Louis, MO include:
  • Independence Day, vibrant fireworks and festive celebrations throughout the city
  • Labor Day, pleasant weather and various outdoor activities
  • Thanksgiving, a time for family gatherings with a charming autumn atmosphere.
The best season to visit St. Louis, MO is Spring or Fall. The best weather to explore St. Louis, MO is during April-May or September-October.
We recommend using the bus as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from Columbus, OH to St. Louis, MO

Most Columbus, OH to St. Louis, MO flights use the John Glenn International Airport to St. Louis Lambert International Airport airport pair. Use this guide to compare Columbus, OH and St. Louis, MO airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.

Departure airports in Columbus
Arrival airports in St. Louis

Which Columbus, OH airport do flights to St. Louis, MO leave from?

Flights from Columbus, OH to St. Louis, MO depart from John Glenn International Airport. The airport is 1 miles (2 km) from Columbus, OH city centre at 4600 Intertiol Gateway, Columbus, OH 43219, USA.
John Glenn International Airport (CMH)4600 Intertiol Gateway, Columbus, OH 43219, USAWifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rental
City-centre transport

Getting to John Glenn International Airport from Columbus city centre

John Glenn International Airport is 2 km from Columbus city centre. Public transport options include:

Bus374 A, 379 A · 15m · CHF16
Route A, Route D · 25m · CHF8
7 · 47m · CHF2 · every ~3 min
7 · 51m · CHF2 · every ~3 min

John Glenn International Airport airport facilities and services

John Glenn International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.

Food and drink

Food options include: Various locations, including American, Italian, and fast food

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are located in all terminals.

Luggage and lost property

Lost and found is available at the station.

Parking, taxis and toilets

Available at John Glenn International Airport: Parking, Taxis, WC.

Bike and car services

Available at John Glenn International Airport: Car Rental.

Accessibility

Accessibility facilities are available at John Glenn International Airport: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Hotels nearby, such as Hilton Garden Inn and Hampton Inn..

More options for your journey from Columbus, OH to St. Louis, MO

Here are some other resources that might have the information you need

Most popular flights to and from St. Louis, MO and Columbus, OH

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone