- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
The best way to find a cheap bus ticket from Columbus, OH to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbus, OH to Harrisburg, PA will cost around $77 if you buy it on the day, but the cheapest tickets can be found for only $71.
On Wed, Nov 04, we found 3 buses from Columbus, OH to Harrisburg, PA, including 3 direct services.
On Wed, Nov 04 the direct buses cover the 521 km distance in an average of 8 h 35 m but if you time it right, some buses will get you there in just 8 h 20 m .
On Wed, Nov 04 the slowest buses will take 9 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Columbus, OH to Harrisburg, PA run on average 5 times per day, taking around 9h 2m. Cheap bus tickets for this journey start at $48 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:40, the last at 21:10. The fastest bus covers the 323 miles (521 km) distance in 8h 15m.
Distance 323 miles (521 km) |
Average bus duration 9h 2m |
Cheapest ticket price $48 |
Buses per day 5 |
Direct buses 5 |
Fastest bus 8h 15m |
First bus 12:40 AM |
Last bus 9:10 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 42 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Columbus, OH to Harrisburg, PA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:40AM | Arrival Time 10:15AM | Duration 9h35 | Departure days Mon | Cheapest price $96 |
Operator Greyhound | Departure Time 12:50AM | Arrival Time 10:25AM | Duration 9h35 | Departure days Tue, Thu | Cheapest price $65 |
Operator Greyhound | Departure Time 01:10AM | Arrival Time 09:30AM | Duration 8h20 | Departure days Thu, Sun | Cheapest price $80 |
Operator Greyhound | Departure Time 02:10AM | Arrival Time 10:30AM | Duration 8h20 | Departure days Thu | Cheapest price $74 |
Operator Flixbus USA | Departure Time 03:45AM | Arrival Time 12:10PM | Duration 8h25 | Departure days Mon, Tue, Thu | Cheapest price $58 |
Operator Greyhound | Departure Time 05:40AM | Arrival Time 03:15PM | Duration 9h35 | Departure days Sun | Cheapest price $60 |
Operator Greyhound USA | Departure Time 02:00PM | Arrival Time 11:05PM | Duration 9h05 | Departure days Mon, Tue, Thu | Cheapest price $82 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 01:35AM | Duration 8h15 | Departure days Thu | Cheapest price $61 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 03:05AM | Duration 9h05 | Departure days Wed, Fri, Sat | Cheapest price $65 |
Operator Greyhound | Departure Time 08:45PM | Arrival Time 05:35AM | Duration 8h50 | Departure days Tue, Thu | Cheapest price $60 |
The table below shows live departures for Columbus, OH to Harrisburg, PA buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 PM Columbus, E Mound St (Akili Christian High School), OH | 9h15 | 11:15 PM Harrisburg, Market St (Bus Station), PA | 0 transfersDirect | |
| Wednesday, November 4 | |||||
![]() | 1:10 AM Columbus, OH | 8h20 | 9:30 AM Harrisburg, PA | 0 transfersDirect | |
| Tuesday, November 3 | |||||
![]() | 8:45 PM Columbus, E Mound St (Akili Christian High School), OH | 8h50 | 5:35 AM Harrisburg, Market St (Bus Station), PA | 0 transfersDirect | |
| Wednesday, November 4 | |||||
![]() | 2:10 AM Columbus, OH | 8h20 | 10:30 AM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Harrisburg, PA.
Find answers to the most common questions about traveling from Columbus, OH to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Columbus, OH to Harrisburg, PA buses use the Columbus, E Mound St (Akili Christian High School) to Harrisburg, Market St (Bus Station) station pair. Use this guide to compare Columbus, OH and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Check bus stations information for Columbus, OH and Harrisburg, PA, including where buses depart and arrive on this route.
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