The cheapest and fastest buses from Ann Arbor, MI to St. Louis, MO
Cheapest price
$71
Average price
$71
Fastest journey
11 h 25 m
Average duration
11 h 25 m
Buses per day
1
Distance
680 km
The best way to find a cheap bus ticket from Ann Arbor, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ann Arbor, MI to St. Louis, MO will cost around $71 if you buy it on the day, but the cheapest tickets can be found for only $71.
Of the 1 buses that leave Ann Arbor, MI for St. Louis, MO on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 680 km distance in an average of 11 h 25 m but if you time it right, some buses will get you there in just 11 h 25 m .
On Sun, Dec 21 the slowest buses will take 11 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Ann Arbor, MI - St. Louis, MOCompare FlixBus, Greyhound


Travel Information
Compare train, bus, and flight for Ann Arbor, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Ann Arbor, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €57. For those with little time consider booking a flight which can get you there in 6h 10m. The ticket price range depends on the travel mode: a bus costs an average of €57, and a flight costs an average of €104.
Distance: 422 miles (680 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€76 Average price Cheapest | €186 Average price | €255 Average price |
15h 17m Average total duration 14h 47m Onboard + 30m Additional time* | 10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 9h 10m Average total duration Fastest 6h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Ann Arbor, MI to St. Louis, MO bus times
The table below shows live departures for Ann Arbor, MI to St. Louis, MO buses for tomorrow, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:15 PM Ann Arbor, MI | 11h25 | 11:40 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ann Arbor, MI to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
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Dec 27
Journey information
Overview: Bus from Ann Arbor, MI to St. Louis, MO
Buses from Ann Arbor, MI to St. Louis, MO run on average 3 times per day, taking around 14h 47m. Cheap bus tickets for this journey start at $71 (€57) if you book in advance.
The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 422 miles (680 km) distance in 14h 5m.
Distance 422 miles (680 km) |
Average bus duration 14h 47m |
Cheapest ticket price $71 (€57) |
Buses per day 3 |
Fastest bus 14h 5m |
First bus 00:45 |
Last bus 23:30 |
Bus providers: Greyhound, FlixBus from Ann Arbor, MI to St. Louis, MOYou can travel by bus between Ann Arbor, MI to St. Louis, MO with Greyhound, FlixBus for as low as $71 (€57). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Ann Arbor, MI to St. Louis, MO
Find answers to the most common questions about traveling from Ann Arbor, MI to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Ann Arbor, MI to St. Louis, MO, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Ann Arbor, MI to St. Louis, MO
More options for your journey from Ann Arbor, MI to St. Louis, MO
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