- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
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The cheapest and fastest buses from Ann Arbor, MI to St. Louis, MO
Showing times and prices for Jun 20
Cheapest price
$148
Average price
$154
Fastest journey
14 h
Average duration
14 h 30 m
Buses per day
2
Distance
680 km
Cheap tickets
The best way to find a cheap bus ticket from Ann Arbor, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ann Arbor, MI to St. Louis, MO will cost around $154 if you buy it on the day, but the cheapest tickets can be found for only $148.
Fast buses
Of the 2 buses that leave Ann Arbor, MI for St. Louis, MO on Sat, Jun 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 680 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 14 h .
On Sat, Jun 20 the slowest buses will take 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:20 PM15h00Ann Arbor, MI4:20 AMSt. Louis, MO$1481One-way0 transfers- 9:25 PM14h00Ann Arbor, MI11:25 AMSt. Louis, MO$1601One-way0 transfers
- 9:25 PM14h00Ann Arbor, MI11:25 AMSt. Louis, MO$1601One-way0 transfers
- 1:20 PM15h00Ann Arbor, MI4:20 AMSt. Louis, MO$1481One-way0 transfers
Travel Information
Compare train, bus, and flight for Ann Arbor, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Ann Arbor, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $77. For those with little time consider booking a flight which can get you there in 5h 46m. The ticket price range depends on the travel mode: a bus costs an average of $77, and a flight costs an average of $181.
Distance: 422 miles (680 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$154 Average price Cheapest | $155 Average price | $406 Average price |
15h 2m Average total duration 14h 32m Onboard + 30m Additional time* | 10h 13m Average total duration 9h 43m Onboard + 30m Additional time* | 8h 46m Average total duration Fastest 5h 46m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Ann Arbor, MI to St. Louis, MO is a bus with an average price of $154 (€126).
This is compared to other travel options from Ann Arbor, MI to St. Louis, MO:
A bus is $1 (€0.95) less than a train for this route with tickets for a train from Ann Arbor, MI to St. Louis, MO costing on average $155 (€127).
A bus is $253 (€207) less than a flight for this route with tickets for a flight from Ann Arbor, MI to St. Louis, MO costing on average $406 (€333).
The fastest way to travel from Ann Arbor, MI to St. Louis, MO is by flight with an average journey time of 5h 46m.
Other travel options to St. Louis, MO take longer:
Train takes on average 9h 43m.
Bus takes on average 14h 32m.
It's helpful to compare your options as there are 3 ways to travel between Ann Arbor, MI and St. Louis, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Ann Arbor, MI to St. Louis, MO among Omio's users.
Ann Arbor, MI to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:35AM | Arrival Time 03:40PM | Duration 15h05 | Departure days Sun | Cheapest price $118 |
Operator Greyhound | Departure Time 04:35AM | Arrival Time 08:20PM | Duration 15h45 | Departure days Wed, Fri | Cheapest price $151 |
Operator Greyhound USA | Departure Time 09:20AM | Arrival Time 11:10PM | Duration 13h50 | Departure days Sun | Cheapest price $118 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 04:20AM | Duration 15h00 | Departure days Mon, Fri, Sat | Cheapest price $148 |
Operator D2A2 | Departure Time 02:15PM | Arrival Time 07:55AM | Duration 17h40 | Departure days Sun | Cheapest price $151 |
Operator Greyhound USA | Departure Time 05:25PM | Arrival Time 06:25AM | Duration 13h00 | Departure days Sun | Cheapest price $118 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 11:25AM | Duration 14h00 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $139 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 12:25PM | Duration 14h00 | Departure days Tue, Wed, Thu | Cheapest price $77 |
Live departures
Ann Arbor, MI to St. Louis, MO bus times
The table below shows live departures for Ann Arbor, MI to St. Louis, MO buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:25 PM Ann Arbor, MI | 14h00 | 11:25 AM St. Louis, MO | 0 transfersDirect | |
| Saturday, June 20 | |||||
| 1:20 PM Ann Arbor, MI | 15h00 | 4:20 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ann Arbor, MI to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Ann Arbor, MI to St. Louis, MO buses with Omio?
D2A2 as well as Greyhound offer buses services from Ann Arbor, MI to St. Louis, MO.
Omio is the only official third party seller for D2A2 tickets.
Why book with Omio vs D2A2?
- Compare with other providers: On Omio, you can not only buy tickets for D2A2, but also compare tickets for the likes of Greyhound to find the best option for your trip from Ann Arbor, MI to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare D2A2 with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Ann Arbor, MI to St. Louis, MO.
Journey information
Overview: Bus from Ann Arbor, MI to St. Louis, MO
USAUSA
Buses from Ann Arbor, MI to St. Louis, MO run on average 3 times per day, taking around 14h 32m. Cheap bus tickets for this journey start at $77 (€63) but you can travel from only $77 (€63) by train.
The earliest bus runs at 00:35, the last at 23:30. The fastest bus covers the 422 miles (680 km) distance in 14h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $77 (€63)
Distance 422 miles (680 km) |
Average bus duration 14h 32m |
Cheapest ticket price $77 (€63) |
Buses per day 3 |
Fastest bus 14h 0m |
First bus 12:35 AM |
Last bus 11:30 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $77 (€63)
Bus providers: D2A2, Greyhound from Ann Arbor, MI to St. Louis, MOYou can travel by bus between Ann Arbor, MI to St. Louis, MO with D2A2, Greyhound for as low as $77 (€63). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
15h 35m
Cheapest Price
$151 (€123)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
D2A2
Luggage & cancellation policy
Average Duration
17h 10m
Cheapest Price
$151 (€124)
D2A2 frequency
1 a day
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
- Recommended
The Delmar Loop
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Toasted Ravioli
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
- Vegetarian
Gooey Butter Cake
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
Charlie Gitto's On The Hill
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
Ted Drewes Frozen Custard
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
Sidney Street Cafe
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
United States Dollar
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 70+ per person before drinks and tip.
- Coffee
- USD 3-6 for regular coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Ann Arbor, MI to St. Louis, MO
Find answers to the most common questions about traveling from Ann Arbor, MI to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Ann Arbor, MI to St. Louis, MO can start from as little as $77 (€63) when you book in advance. The average bus ticket price for Ann Arbor, MI to St. Louis, MO is $154 (€126) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Ann Arbor, MI to St. Louis, MO is 14h 0m to travel the 422 miles (680 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Ann Arbor, MI to St. Louis, MO leaves at 12:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Ann Arbor, MI to St. Louis, MO leaves at 11:30 PM.
There are 3 buses a day from Ann Arbor, MI to St. Louis, MO which require at least one change with D2A2, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Ann Arbor, MI to St. Louis, MO, you can count on D2A2, Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Ann Arbor, MI and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Ann Arbor, MI is worth doing but not as a day trip with a journey time of 14h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Ann Arbor, MI to St. Louis, MO is October.
It's helpful to compare your options as there are 3 ways to travel between Ann Arbor, MI and St. Louis, MO including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Ann Arbor, MI to St. Louis, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Ann Arbor, MI to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Ann Arbor, MI to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Ann Arbor, MI to St. Louis, MO.
You can reserve your seat on the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound.
Since neither Ann Arbor, MI nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Ann Arbor, MI to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Ann Arbor, MI to St. Louis, MO
Ann Arbor
St. Louis
The major bus station for departures in Ann Arbor is Ann Arbor, Amtrak Station. Find all the information you need to know about services, amenities and connections at Ann Arbor, Amtrak Station for your trip from Ann Arbor to St. Louis.
Ann Arbor, Amtrak Station
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Ann Arbor.
St. Louis, S 15th St (Civic center)
information
Most popular bus connections from Ann Arbor, MI
More options for your journey from Ann Arbor, MI to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Ann Arbor, MI
Most popular bus connections to St. Louis, MO
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