- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Ann Arbor, MI to St. Louis, MO
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$148
Average ticket price on Sep 19
$154
Fastest journey on Sep 19
14 h
Average journey duration on Sep 19
14 h 30 m
Buses on Sep 19
2
Distance
680 km
Cheap tickets
The best way to find a cheap bus ticket from Ann Arbor, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ann Arbor, MI to St. Louis, MO will cost around $154 if you buy it on the day, but the cheapest tickets can be found for only $148.
Fast buses
On Sat, Sep 19, we found 2 buses from Ann Arbor, MI to St. Louis, MO, including 2 direct services.
On Sat, Sep 19 the direct buses cover the 680 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 14 h .
On Sat, Sep 19 the slowest buses will take 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:20 PM15h00Ann Arbor, MI4:20 AMSt. Louis, MO$1481One-way0 transfers- 9:25 PM14h00Ann Arbor, MI11:25 AMSt. Louis, MO$1601One-way0 transfers
- 9:25 PM14h00Ann Arbor, MI11:25 AMSt. Louis, MO$1601One-way0 transfers
- 1:20 PM15h00Ann Arbor, MI4:20 AMSt. Louis, MO$1481One-way0 transfers
Travel Information
Compare train, bus, and flight for Ann Arbor, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Ann Arbor, MI to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $128 For those with little time, consider booking a flight, which has an average total journey time of 6h 24m. Average ticket prices depend on the travel mode: a bus costs an average of $128, while a flight costs an average of $760.
Distance: 422 miles (680 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$128 Average price Cheapest | $253 Average price | $760 Average price |
13h 0m Average total duration 12h 30m Onboard + 30m Additional time* | 10h 7m Average total duration 9h 37m Onboard + 30m Additional time* | 6h 24m Average total duration Fastest 4h 24m Onboard + 2h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Ann Arbor, MI to St. Louis, MO is a bus with an average price of $128.
This is compared to other travel options from Ann Arbor, MI to St. Louis, MO:
A bus is $125 less than a train for this route with tickets for a train from Ann Arbor, MI to St. Louis, MO costing on average $253.
A bus is $632 less than a flight for this route with tickets for a flight from Ann Arbor, MI to St. Louis, MO costing on average $760.
The fastest way to travel from Ann Arbor, MI to St. Louis, MO is by flight with an average journey time of 4h 24m.
Other travel options to St. Louis, MO take longer:
Train takes on average 9h 37m.
Bus takes on average 12h 30m.
It's helpful to compare your options as there are 3 ways to travel between Ann Arbor, MI and St. Louis, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Ann Arbor, MI to St. Louis, MO among Omio's users.
Ann Arbor, MI to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:35AM | Arrival Time 03:40PM | Duration 15h05 | Departure days Sun | Cheapest price $119 |
Operator Greyhound | Departure Time 04:35AM | Arrival Time 08:20PM | Duration 15h45 | Departure days Wed, Fri | Cheapest price $151 |
Operator Greyhound USA | Departure Time 09:20AM | Arrival Time 11:10PM | Duration 13h50 | Departure days Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 04:20AM | Duration 15h00 | Departure days Mon, Fri, Sat | Cheapest price $148 |
Operator D2A2 | Departure Time 02:15PM | Arrival Time 07:55AM | Duration 17h40 | Departure days Sun | Cheapest price $152 |
Operator Greyhound USA | Departure Time 05:25PM | Arrival Time 06:25AM | Duration 13h00 | Departure days Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 11:25AM | Duration 14h00 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $139 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 12:25PM | Duration 14h00 | Departure days Tue, Wed, Thu | Cheapest price $77 |
Live departures
Ann Arbor, MI to St. Louis, MO bus times
The table below shows live departures for Ann Arbor, MI to St. Louis, MO buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 4:35 AM Ann Arbor, MI | 15h45 | 8:20 PM St. Louis, MO | 0 transfersDirect | |
| 1:20 PM Ann Arbor, MI | 15h00 | 4:20 AM St. Louis, MO | 0 transfersDirect | |
| 9:25 PM Ann Arbor, MI | 14h00 | 11:25 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ann Arbor, MI to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Sep 19
Sep 19
Sun
Sep 20
Sep 20
Mon
Sep 21
Sep 21
Tue
Sep 22
Sep 22
Wed
Sep 23
Sep 23
Thu
Sep 24
Sep 24
Fri
Sep 25
Sep 25
Why should you book Ann Arbor, MI to St. Louis, MO buses with Omio?
D2A2 as well as Greyhound offer buses services from Ann Arbor, MI to St. Louis, MO.
Omio is the only official third party seller for D2A2 tickets.
Why book with Omio vs D2A2?
- Compare with other providers: On Omio, you can not only buy tickets for D2A2, but also compare tickets for the likes of Greyhound to find the best option for your trip from Ann Arbor, MI to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare D2A2 with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Ann Arbor, MI to St. Louis, MO.
Journey information
Overview: Bus from Ann Arbor, MI to St. Louis, MO
USAUSA
Buses from Ann Arbor, MI to St. Louis, MO run on average 3 times per day, taking around 12h 30m. Cheap bus tickets for this journey start at $84 if you book in advance.
The earliest bus runs at 00:35, the last at 23:30. The fastest bus covers the 422 miles (680 km) distance in 11h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 422 miles (680 km) |
Average bus duration 12h 30m |
Cheapest ticket price $84 |
Buses per day 3 |
Fastest bus 11h 5m |
First bus 12:35 AM |
Last bus 11:30 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Ann Arbor, MI to St. Louis, MOYou can travel by bus between Ann Arbor, MI to St. Louis, MO with FlixBus, Greyhound for as low as $93. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
11h 5m
Cheapest FlixBus Price
$86
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
12h 40m
Cheapest Greyhound Price
$84
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Ann Arbor, MI to St. Louis, MO
Find answers to the most common questions about traveling from Ann Arbor, MI to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Ann Arbor, MI to St. Louis, MO can start from as little as $84 when you book in advance. The average bus ticket price for Ann Arbor, MI to St. Louis, MO is $128 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Ann Arbor, MI to St. Louis, MO is 11h 5m to travel the 422 miles (680 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Ann Arbor, MI to St. Louis, MO leaves at 12:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Ann Arbor, MI to St. Louis, MO leaves at 11:30 PM.
There are 3 buses a day from Ann Arbor, MI to St. Louis, MO which require at least one change with D2A2, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Ann Arbor, MI to St. Louis, MO, you can count on D2A2, Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Ann Arbor, MI and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Ann Arbor, Amtrak Station, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Ann Arbor, MI is worth doing but not as a day trip with a journey time of 11h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Ann Arbor, MI to St. Louis, MO is October.
It's helpful to compare your options as there are 3 ways to travel between Ann Arbor, MI and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Ann Arbor, MI to St. Louis, MO for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Ann Arbor, MI to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Ann Arbor, MI to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Ann Arbor, MI to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Ann Arbor, MI to St. Louis, MO.
You can reserve your seat on the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Ann Arbor, MI to St. Louis, MO with the following bus company: Greyhound.
Since neither Ann Arbor, MI nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Ann Arbor, MI to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Ann Arbor, MI to St. Louis, MO
Most Ann Arbor, MI to St. Louis, MO buses use the Ann Arbor, Amtrak Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Ann Arbor, MI and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Ann Arbor
Arrival bus stations in St. Louis
Which Ann Arbor, MI station do buses to St. Louis, MO leave from?
Buses from Ann Arbor, MI to St. Louis, MO leave from Ann Arbor, Amtrak Station. The station is 0 miles (1 km) from Ann Arbor, MI city centre at Amtrak Station, 325 Depot St, Ann Arbor, MI 48104, USA.
Ann Arbor, Amtrak StationAmtrak Station, 325 Depot St, Ann Arbor, MI 48104, USA
City-centre transport
Getting to Ann Arbor, Amtrak Station from Ann Arbor city centre
Ann Arbor, Amtrak Station is 1 km from Ann Arbor city centre. Public transport options include:
TRUE
Ann Arbor, Amtrak Station bus station facilities and services
Ann Arbor, Amtrak Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the waiting area. ATMs are available at Ann Arbor, Amtrak Station.
Tickets and information
Ticket office support is available at Ann Arbor, Amtrak Station.
Parking, taxis and toilets
Available at Ann Arbor, Amtrak Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Ann Arbor, Amtrak Station: Station is wheelchair accessible with ramps.
Which St. Louis, MO station do buses from Ann Arbor, MI arrive at?
Buses from Ann Arbor, MI to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
More options for your journey from Ann Arbor, MI to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Ann Arbor, MI
Most popular bus connections to St. Louis, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
