The cheapest and fastest trains from Ann Arbor, MI to St. Louis, MO
Cheapest price
$250
Average price
$250
Fastest journey
11 h 53 m
Average duration
13 h 38 m
Trains per day
3
Distance
680 km
The best way to find a cheap train ticket from Ann Arbor, MI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ann Arbor, MI to St. Louis, MO will cost around $250 if you buy it on the day, but the cheapest tickets can be found for only $250.
It's difficult to get from Ann Arbor, MI to St. Louis, MO without transferring at least once.






Travel Information
Compare train, bus, and flight for Ann Arbor, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Ann Arbor, MI to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €57. For those with little time consider booking a flight which can get you there in 6h 10m. The ticket price range depends on the travel mode: a bus costs an average of €57, and a flight costs an average of €104.
Distance: 422 miles (680 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€186 Average price | €255 Average price | €76 Average price Cheapest |
10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 9h 10m Average total duration Fastest 6h 10m Onboard + 3h 0m Additional time* | 15h 17m Average total duration 14h 47m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Ann Arbor, MI to St. Louis, MO train times
The table below shows live departures for Ann Arbor, MI to St. Louis, MO trains for today, Thursday, December 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:14 AM Ann Arbor, MI | 12h53 | 12:07 AM St. Louis, MO | 0 transfersDirect | |
![]() | 2:23 PM Ann Arbor, MI | 13h00 | 3:23 AM St. Louis, MO | 0 transfersDirect | |
| Friday, December 5 | |||||
![]() | 7:14 AM Ann Arbor, MI | 11h53 | 7:07 PM St. Louis, MO | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ann Arbor, MI to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 05
Dec 06
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Dec 11
Why should you book Ann Arbor to St. Louis trains with Omio?
Amtrak operates all train services from Ann Arbor to St. Louis. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Ann Arbor to St. Louis.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Ann Arbor to St. Louis.
Journey information
Overview: Train from Ann Arbor, MI to St. Louis, MO
Trains from Ann Arbor, MI to St. Louis, MO run on average 2 times per day, taking around 9h 30m. Cheap train tickets for this journey start at $106 (€85) but you can travel from only $70 (€57) by bus.
The earliest train runs at 04:30, the last at 10:25. The fastest train covers the 422 miles (680 km) distance in 12h 53m.
Distance 422 miles (680 km) |
Average train duration 9h 30m |
Cheapest ticket price $106 (€85) |
Trains per day 2 |
Fastest train 12h 53m |
First train 04:30 |
Last train 10:25 |
Train companies: Amtrak from Ann Arbor, MI to St. Louis, MO trainsAmtrak trains will get you between Ann Arbor, MI and St. Louis, MO from $70 (€57). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Ann Arbor, MI to St. Louis, MO
Find answers to the most common questions about traveling from Ann Arbor, MI to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Ann Arbor, MI to St. Louis, MO
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps.
- Free for passengers
- Graduate Ann Arbor
- Residence Inn by Marriott Ann Arbor Downtown
- Bell Tower Hotel
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area and a single platform for Amtrak services.
- Bus: TheRide routes available
- Taxi services available
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from Ann Arbor, MI
More options for your journey from Ann Arbor, MI to St. Louis, MO
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