Travel Information
Compare train, bus, and flight for Prague to Pisa
Omio recommends booking the flight as it is the most popular option from Prague to Pisa among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $129 For those with little time, consider booking a flight, which has an average total journey time of 5h 25m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.8 - 1.9kg. Average ticket prices depend on the travel mode: a bus costs an average of $129, while a flight costs an average of $568.
Distance: 479 miles (771 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$568 Average price | $129 Average price Cheapest | $282 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 3h 25m Onboard + 2h 0m Additional time* | 18h 10m Average total duration 17h 40m Onboard + 30m Additional time* | 11h 27m Average total duration (door-to-door) |
2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Prague to Pisa
Compare the available ways to get from Prague to Pisa, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Pisa:
A bus is $440 (€370) less than a flight for this route with tickets for a flight from Prague to Pisa costing on average $568 (€479).
Other travel options to Pisa take longer:
Bus takes on average 18h 10m.
You'll arrive about 8h 2m sooner (3h 25m by flight vs 11h 27m by car). Tickets start at around $568 (€479) compared to roughly $282 (€238) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Prague to Pisa
How to get from Prague to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Prague to Pisa is by taking a bus because it’s the best combination of price and speed.
FlixBus9:25 PM 16h25 Praha, ÚAN Florenc 1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) $80 1 One-way 0 transfers
Cheapest
FlixBus9:25 PM 16h25 Praha, ÚAN Florenc 1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) $80 1 One-way 0 transfers
Fastest
FR 82325:00 PM 1h40 Prague Vaclav Havel Airport 6:40 PM Pisa International Airport $98 1 One-way 0 transfers
Other options
FlixBus · FlixBus · FlixBus3:00 PM 22h50 Praha, Černý Most 1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) $108 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus2:30 PM 22h50 Praha, Černý Most 1:20 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) $108 1 One-way 2 transfers
FlixBus · FlixBus5:45 PM 20h05 Prague, Central Train Station 1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) $108 1 One-way 1 transfer
Regionale 20729 · Regionale Veloce 4140+
W460663:15 PM 9h00 Prague Vaclav Havel Airport 12:15 AM Pisa Centrale $131 1 One-way 2 transfers
Regionale 20721+
Intercity 522+
W460663:15 PM 7h35 Prague Vaclav Havel Airport 10:50 PM Pisa Centrale $136 1 One-way 2 transfers
Regionale 20727+
W46066+
FRECCIARGENTO 85963:15 PM 7h25 Prague Vaclav Havel Airport 10:40 PM Pisa Centrale $151 1 One-way 2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Pisa.

This is compared to other travel options from Prague to Pisa:
A bus is $440 (€370) less than a flight for this route with tickets for a flight from Prague to Pisa costing on average $568 (€479).
Other travel options to Pisa take longer:
Bus takes on average 18h 10m.
- Around 11 flights per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Pisa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Pisa International Airport.
- Buses mostly depart from Prague, Central Train Station and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with Transavia France, Air Dolomiti, British Airways, Eurowings, Malta Air, Buzz, Austrian Airlines, Brussels Airlines, Smartwings, Swiss, Ryanair to go to Pisa by flight.
- Travel with FlixBus to go to Pisa by bus.
- 1 direct flights per day with Malta Air, Buzz, Ryanair.
- 1 direct buses per day with FlixBus.
Travelling from Prague to Pisa: related information
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