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Compare bus, train, and flight for Milan to Prague
Omio recommends booking the flight as it is the most popular option from Milan to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €42. For those with little time consider booking a flight which can get you there in 2h 56m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of €42, and a train costs an average of €102.
Distance: 401 miles (646 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
€129 Average price | €68 Average price Cheapest | €172 Average price |
5h 56m Average total duration Fastest 2h 56m Onboard + 3h 0m Additional time* | 13h 36m Average total duration 13h 6m Onboard + 30m Additional time* | 15h 16m Average total duration 14h 46m Onboard + 30m Additional time* |
1.9 - 3.9kg CO2 emissions | 0.6 - 1.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Milan to Prague
How to get from Milan to Prague by train, bus or flight.
Our recommendation
The best way to travel from Milan to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
U23901Other options
FlixBus
FlixBus
FlixBus · FlixBus
DE4356 · DE4409
FR 3530
EW9823 · EW9772Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Milan to Prague
The Best Way According to our Users
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FAQs: Travel from Milan to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Prague.

This is compared to other travel options from Milan to Prague:
A flight is $27 (€21) less than a bus for this route with tickets for a bus from Milan to Prague costing on average $52 (€41).
A flight is $28 (€22) less than a train for this route with tickets for a train from Milan to Prague costing on average $53 (€42).
Other travel options to Prague take longer:
Bus takes on average 13h 40m.
Train takes on average 15h 28m.
- Around 80 flights per day.
- Around 32 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Milan and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Malpensa Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Milan Centrale and arrive in Prague hlavní nádraží.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Praha, ÚAN Florenc.
- Travel with easyJet, KM Malta Airlines, Ryanair, Buzz, Wizz Air, Lufthansa, Air Dolomiti, Condor, KLM, Eurowings , Austrian Airlines, Air France, SWISS, LAER, Brussels Airlines, Air Serbia, LOT Polish Airlines, KLM Cityhopper, Norwegian Air to go to Prague by flight.
- Travel with FlixBus, Infobus, BlaBlaCar Bus, Musil Tour to go to Prague by bus.
- Travel with Deutsche Bahn to go to Prague by train.
- 4 direct flights per day with easyJet, KM Malta Airlines, Ryanair, Buzz.
- 2 direct buses per day with FlixBus, Infobus, Musil Tour.
Travelling from Milan to Prague: related information
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