4.9
4.6
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a flight costs an average of $111.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$159 Average price | $58 Average price Cheapest | $304 Average price | $193 Average price (fuel + tolls) |
5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Brussels:
A bus is $101 (€84) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $159 (€131).
A bus is $246 (€204) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $304 (€251).
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
Travel optionsfrom Lyon to Brussels
How to get from Lyon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.
- 4788 · 503276:15 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:30 PMBrussels, Brussels South (Gare du Midi)$531One-way1 transfer
Cheapest
- 4788 · 503276:15 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:30 PMBrussels, Brussels South (Gare du Midi)$531One-way1 transfer
Fastest
SN35881:10 PM1h25Lyon Saint Exupery Airport2:35 PMBrussels Airport$2911One-way0 transfers
Other options
- 98525:50 AM4h02Lyon Part Dieu9:52 AMBrussels-Midi$1031One-way0 transfers
- 6690+
93657:04 AM11h13Lyon Part Dieu6:17 PMBrussels-Midi$1631One-way1 transfer 
17758+948911:16 AM11h01Lyon Part Dieu10:17 PMBrussels-Midi$1641One-way1 transfer
- 83134 · 980808:30 AM10h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)7:10 PMBrussels, Brussels South (Gare du Midi)$581One-way1 transfer
- 94782 · 14662:30 AM11h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:30 PMBrussels, Brussels South (Gare du Midi)$681One-way1 transfer
- 94742 · 16571:30 AM10h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)$701One-way1 transfer
VY1223 · VY89806:00 PM15h45Lyon Saint Exupery Airport9:45 AMBrussels Airport$2611One-way1 transfer- VY1221 · VY89869:45 AM4h45Lyon Saint Exupery Airport2:30 PMBrussels Airport$2771One-way1 transfer
- VY1221 · VY89829:45 AM7h40Lyon Saint Exupery Airport5:25 PMBrussels Airport$2771One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Lyon to Brussels
The Best Way According to our Users
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FAQs: Travel from Lyon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.
This is compared to other travel options from Lyon to Brussels:
A bus is $101 (€84) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $159 (€131).
A bus is $246 (€204) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $304 (€251).
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
- Around 14 buses per day.
- Around 12 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar, Alsa to go to Brussels by bus.
- Travel with SNCF | TGV INOUI, TGV to go to Brussels by train.
- Travel with Brussels Airlines, Air Baltic, Lufthansa, Vueling, Austrian Airlines, KLM, Swiss, easyJet to go to Brussels by flight.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
- 4 direct trains per day with SNCF | TGV INOUI, TGV.
- 2 direct flights per day with Brussels Airlines, Air Baltic, Swiss, easyJet.
Travelling from Lyon to Brussels: related information
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