Travel Information
Compare train, bus, and flight for Brussels to Lyon
Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 2h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $129.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$159 Average price | $53 Average price Cheapest | $315 Average price |
4h 14m Average total duration 3h 44m Onboard + 30m Additional time* | 10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Brussels to Lyon
How to get from Brussels to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Lyon is by taking a bus because it’s the best combination of price and speed.
1430 · 504718:05 AM11h05Brussels, Brussels South (Gare du Midi)7:10 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$581One-way1 transfer
Cheapest
1408 · 831335:55 PM10h10Brussels, Brussels South (Gare du Midi)4:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way1 transfer
Fastest
SN358711:00 AM1h25Brussels Airport12:25 PMLyon Saint Exupery Airport$5371One-way0 transfers
Other options
9440+
66211:13 PM4h47Brussels-Midi6:00 PMLyon Part Dieu$2071One-way1 transfer
9440+
66211:13 PM5h01Brussels-Midi6:14 PMGare de Lyon-Perrache$2071One-way1 transfer
9410+
66118:13 AM4h43Brussels-Midi12:56 PMLyon Part Dieu$2261One-way1 transfer
1660 · 506174:35 PM10h55Brussels, Brussels South (Gare du Midi)3:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$451One-way1 transfer
1646 · 501071:30 PM10h50Brussels, Brussels South (Gare du Midi)12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$561One-way1 transfer
50338 · 508837:05 PM10h20Brussels, Brussels South (Gare du Midi)5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$581One-way1 transfer
KL1704+
KL1407+
984410:25 AM11h35Brussels Airport10:00 PMLyon Part Dieu$4591One-way2 transfers
KL1704+
KL1407+
983010:25 AM6h34Brussels Airport4:59 PMLyon Part Dieu$5691One-way2 transfers
KL1704+
KL1407+
983610:25 AM9h37Brussels Airport8:02 PMLyon Part Dieu$5691One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Brussels to Lyon
The Best Way According to our Users
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FAQs: Travel from Brussels to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Lyon.

This is compared to other travel options from Brussels to Lyon:
A bus is $37 (€29) less than a train for this route with tickets for a train from Brussels to Lyon costing on average $61 (€48).
A bus is $106 (€84) less than a flight for this route with tickets for a flight from Brussels to Lyon costing on average $129 (€103).
Other travel options to Lyon take longer:
Train takes on average 3h 42m.
Bus takes on average 9h 50m.
- Around 17 buses per day.
- Around 11 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Brussels and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Brussels-Midi and arrive in Lyon Part Dieu.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Lyon, Perrache Bus Station.
- Travel with TGV, TGV INOUI to go to Lyon by train.
- Travel with Brussels Airlines, Air Baltic, Lufthansa Cityline, Vueling Airlines, Cityjet, easyJet, KLM Cityhopper, KLM to go to Lyon by flight.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Lyon by bus.
- 4 direct trains per day with TGV, TGV INOUI.
- 2 direct flights per day with Air Baltic, easyJet.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
Travelling from Brussels to Lyon: related information
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