Travel Information
Compare train and bus for Brussels to Karlsruhe
Omio recommends booking the train as it is the most popular option from Brussels to Karlsruhe among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €42 For those with little time, consider booking a flight, which has an average total journey time of 3h 10m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of €42, while a flight costs an average of €461.
Distance: 219 miles (354 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€111 Average price | €42 Average price Cheapest | €461 Average price | €72 Average price (fuel + tolls) |
4h 59m Average total duration 4h 29m Onboard + 30m Additional time* | 9h 8m Average total duration 8h 38m Onboard + 30m Additional time* | 3h 10m Average total duration Fastest 1h 10m Onboard + 2h 0m Additional time* | 4h 44m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | 1.1 - 2.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Brussels to Karlsruhe
Compare the available ways to get from Brussels to Karlsruhe, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Brussels to Karlsruhe:
A bus is €70 less than a train for this route with tickets for a train from Brussels to Karlsruhe costing on average €111.
A bus is €420 less than a flight for this route with tickets for a flight from Brussels to Karlsruhe costing on average €461.
Other travel options to Karlsruhe take longer:
Train takes on average 4h 59m.
Bus takes on average 9h 8m.
You'll arrive about 15m sooner (4h 29m by train vs 4h 44m by car). Tickets start at around €111 compared to roughly €72 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Brussels to Karlsruhe
How to get from Brussels to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus4:15 PM 11h00 Brussels, Brussels South (Gare du Midi) 3:15 AM Karlsruhe Hbf €37 1 One-way 1 transfer
Cheapest
FlixBus · FlixBus4:15 PM 11h00 Brussels, Brussels South (Gare du Midi) 3:15 AM Karlsruhe Hbf €37 1 One-way 1 transfer
Fastest
SN2617+
ICE 2057:30 PM 3h30 Brussels Airport 11:00 PM Karlsruhe Hbf €477 1 One-way 1 transfer
Other options
IC 522 · R 5005 · 26809 · ICE 51312:20 AM 9h39 Brussels-Midi 9:59 AM Karlsruhe €64 1 One-way 4 transfers
ICE 11 · IC 2040 · ICE 2796:31 AM 5h28 Brussels-North 11:59 AM Karlsruhe Hbf €114 1 One-way 2 transfers
ICE 13 · ICE 2013 · ICE 371 · STR 38:25 AM 5h48 Brussels-Midi 2:13 PM Europaplatz/Post Galerie (Karlstraße) €116 1 One-way 3 transfers
FlixBus · FlixBus3:40 PM 12h10 Brussels, Avenue des Magnolias (King Baudouin) 3:50 AM Karlsruhe Hbf €38 1 One-way 1 transfer
FlixBus · FlixBus1:20 AM 12h35 Brussels, Brussels South (Gare du Midi) 1:55 PM Karlsruhe Hbf €39 1 One-way 1 transfer
KL1706 · KL1821+
ICE 2052:45 PM 8h15 Brussels Airport 11:00 PM Karlsruhe Hbf €299 1 One-way 2 transfers
KL1704 · KL1821+
ICE 20510:45 AM 12h15 Brussels Airport 11:00 PM Karlsruhe Hbf €299 1 One-way 2 transfers
KL1704 · KL1819+
ICE 20510:45 AM 12h15 Brussels Airport 11:00 PM Karlsruhe Hbf €299 1 One-way 2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Brussels to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Karlsruhe.

This is compared to other travel options from Brussels to Karlsruhe:
A bus is €70 less than a train for this route with tickets for a train from Brussels to Karlsruhe costing on average €111.
A bus is €420 less than a flight for this route with tickets for a flight from Brussels to Karlsruhe costing on average €461.
Other travel options to Karlsruhe take longer:
Train takes on average 4h 59m.
Bus takes on average 9h 8m.
- Around 6 flights per day.
- Around 5 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Brussels and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Brussels-Midi and arrive in Karlsruhe Hbf.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Karlsruhe Hbf.
- Travel with Brussels Airlines to go to Karlsruhe by flight.
- Travel with Deutsche Bahn, Intercity to go to Karlsruhe by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Karlsruhe by bus.
- 6 direct flights per day with Brussels Airlines.
- 0 direct buses per day with FlixBus.
Travelling from Brussels to Karlsruhe: related information
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