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Compare train and bus for Karlsruhe to Madrid
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from $75. For those with little time consider booking a train which can get you there in 12h 28m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a bus costs an average of $75, and a train costs an average of $580.
Distance: 837 miles (1348 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$109 Average price Cheapest | $580 Average price | $486 Average price (fuel + tolls) |
26h 18m Average total duration 25h 48m Onboard + 30m Additional time* | 12h 58m Average total duration Fastest 12h 28m Onboard + 30m Additional time* | 17h 48m Average total duration (door-to-door) |
1.3 - 3.4kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Madrid:
A bus is $471 (€379) less than a train for this route with tickets for a train from Karlsruhe to Madrid costing on average $580 (€466).
Other travel options to Madrid take longer:
Bus takes on average 25h 48m.
Travel optionsfrom Karlsruhe to Madrid
How to get from Karlsruhe to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Madrid is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus11:10 PM32h45Karlsruhe Hbf7:55 AMMadrid, Estación Sur de Autobuses$991One-way1 transfer
Cheapest
FlixBus · FlixBus11:10 PM32h45Karlsruhe Hbf7:55 AMMadrid, Estación Sur de Autobuses$991One-way1 transfer
Fastest
FlixBus · FlixBus6:35 AM25h35Karlsruhe Hbf8:10 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1581One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus11:55 PM31h30Karlsruhe Hbf7:25 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1031One-way2 transfers
FlixBus · FlixBus4:05 AM28h35Karlsruhe Hbf8:40 AMMadrid, Estación Sur de Autobuses$1051One-way1 transfer
FlixBus · FlixBus11:40 PM34h50Karlsruhe Hbf10:30 AMMadrid, Estación Sur de Autobuses$1101One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Madrid.

This is compared to other travel options from Karlsruhe to Madrid:
A bus is $471 (€379) less than a train for this route with tickets for a train from Karlsruhe to Madrid costing on average $580 (€466).
Other travel options to Madrid take longer:
Bus takes on average 25h 48m.
- Around 9 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Madrid as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Karlsruhe Hbf and arrive in Madrid, Estación Sur de Autobuses.
- Travel with FlixBus, BlaBlaCar Bus, Alsa to go to Madrid by bus.
- Travel with AVE, Deutsche Bahn Intercity (DB IC) to go to Madrid by train.
- 1 direct buses per day with BlaBlaCar Bus, Alsa.
Travelling from Karlsruhe to Madrid: related information
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