Travel Information
Compare bus and train for Karlsruhe to Rome
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a train which can get you there in 12h 28m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $49, and a train costs an average of $255.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$86 Average price Cheapest | $376 Average price |
22h 49m Average total duration 22h 19m Onboard + 30m Additional time* | 12h 58m Average total duration Fastest 12h 28m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Karlsruhe to Rome
How to get from Karlsruhe to Rome by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Rome is by taking a bus because it’s the best combination of price and speed.
8:30 AM20h35Karlsruhe5:05 AMRome$561One-way0 transfers
Cheapest
8:30 AM20h35Karlsruhe5:05 AMRome$561One-way0 transfers
Fastest
7:10 PM17h40Karlsruhe12:50 PMRome$841One-way0 transfers
Other options
1:00 PM19h30Karlsruhe8:30 AMRome$571One-way0 transfers
3:30 PM19h45Karlsruhe11:15 AMRome$611One-way0 transfers
4:25 PM23h05Karlsruhe3:30 PMRome$631One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Karlsruhe to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Rome.

This is compared to other travel options from Karlsruhe to Rome:
A bus is $206 (€165) less than a train for this route with tickets for a train from Karlsruhe to Rome costing on average $255 (€204).
Other travel options to Rome take longer:
Bus takes on average 17h 10m.
- Around 13 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Rome as scheduled services by bus and train can vary by season or day of the week.
- Buses mostly depart from Karlsruhe Hbf and arrive in Roma, Autostazione Tiburtina.
- Travel with FlixBus, BlaBlaCar Bus to go to Rome by bus.
- Travel with Eurowings to go to Rome by flight.
- Travel with Trenitalia, Frecciarossa, ÖBB | Railjet, Intercity Notte, Deutsche Bahn to go to Rome by train.
- 1 direct buses per day with FlixBus.
Travelling from Karlsruhe to Rome: related information
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