Travel Information
Compare train and bus for Karlsruhe to Milan
Omio recommends booking the train as it is the most popular option from Karlsruhe to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 6h 26m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $66.
Distance: 247 miles (398 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$168 Average price | $53 Average price Cheapest | $173 Average price (fuel + tolls) |
6h 56m Average total duration Fastest 6h 26m Onboard + 30m Additional time* | 11h 10m Average total duration 10h 40m Onboard + 30m Additional time* | 6h 24m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Karlsruhe to Milan:
A bus is $115 (€94) less than a train for this route with tickets for a train from Karlsruhe to Milan costing on average $168 (€138).
Other travel options to Milan take longer:
Train takes on average 6h 26m.
Bus takes on average 10h 40m.
Travel optionsfrom Karlsruhe to Milan
How to get from Karlsruhe to Milan by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Milan is by taking a bus because it’s the best combination of price and speed.
FlixBus9:30 AM7h20Karlsruhe Hbf4:50 PMMilano, Autostazione Lampugnano$501One-way0 transfers
Cheapest
FlixBus9:30 AM7h20Karlsruhe Hbf4:50 PMMilano, Autostazione Lampugnano$501One-way0 transfers
Fastest
ICE 376 · ICE 614+
LH56367:59 AM6h01Karlsruhe Hbf2:00 PMMilan Malpensa Airport$2581One-way2 transfers
Other options
ECE 1519:11 AM6h42Karlsruhe Hbf3:53 PMMilan Centrale$2071One-way0 transfers
FlixBus8:10 PM9h55Karlsruhe Hbf6:05 AMMilano, Autostazione Lampugnano$531One-way0 transfers
30493 · 474412:25 AM12h45Karlsruhe, Hinterm Hauptbahnhof (Südeingang)1:10 PMMilano, Autostazione Lampugnano$571One-way1 transfer
FlixBus3:20 AM7h55Karlsruhe Hbf11:15 AMMilano, Autostazione Lampugnano$621One-way0 transfers
ICE 202+
U254288:59 AM12h21Karlsruhe Hbf9:20 PMMilan Linate Airport$1791One-way1 transfer
ICE 106+
U254282:59 PM6h21Karlsruhe Hbf9:20 PMMilan Linate Airport$1831One-way1 transfer
ICE 72 · ICE 916+
U254282:37 PM6h43Karlsruhe Hbf9:20 PMMilan Linate Airport$1831One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Karlsruhe to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Milan.

This is compared to other travel options from Karlsruhe to Milan:
A bus is $115 (€94) less than a train for this route with tickets for a train from Karlsruhe to Milan costing on average $168 (€138).
Other travel options to Milan take longer:
Train takes on average 6h 26m.
Bus takes on average 10h 40m.
- Around 8 buses per day.
- Around 1 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Milan as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Karlsruhe/Baden-Baden Airport and arrive in Milan Bergamo Orio al Serio Airport.
- Trains mostly depart from Karlsruhe Hbf and arrive in Milan Centrale.
- Buses mostly depart from Karlsruhe Hbf and arrive in Milano, Autostazione Lampugnano.
- Travel with Ryanair, Malta Air to go to Milan by flight.
- Travel with Deutsche Bahn, Trenitalia, Deutsche Bahn Intercity (DB IC), Nederlandse Spoorwegen (NS) to go to Milan by train.
- Travel with FlixBus, BlaBlaCar Bus, Marino Autolinee to go to Milan by bus.
- 1 direct flights per day with Malta Air.
- 1 direct trains per day with Deutsche Bahn.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, Marino Autolinee.
Travelling from Karlsruhe to Milan: related information
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