- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
$140
Average price
$211
Fastest journey
14 h 55 m
Average duration
15 h 57 m
Trains per day
4
Distance
670 km
The best way to find a cheap train ticket from Pisa to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Palermo will cost around $211 if you buy it on the day, but the cheapest tickets can be found for only $140.
It's difficult to get from Pisa to Palermo without transferring at least once.
FRECCIARGENTO 8591+
InterCityNotte 1959
Regionale 18250+
FRECCIAROSSA 9503+
Intercity 723
Regionale Veloce 4048+
FRECCIAROSSA 9431+
InterCityNotte 1955
InterCityNotte 899+
Intercity 723
Regionale 18250+
FRECCIAROSSA 9503+
Intercity 723
Regionale Veloce 4048+
FRECCIAROSSA 9431+
InterCityNotte 1955
FRECCIARGENTO 8591+
InterCityNotte 1959
InterCityNotte 899+
Intercity 723Trains from Pisa to Palermo run on average 7 times per day, taking around 15h 39m. Cheap train tickets for this journey start at $67 but you can travel from only $21 by flight.
The earliest train runs at 00:03, the last at 23:50. The fastest train covers the 416 miles (670 km) distance in 14h 50m.
Distance 416 miles (670 km) |
Average train duration 15h 39m |
Cheapest ticket price $67 |
Trains per day 7 |
Fastest train 14h 50m |
First train 12:03 AM |
Last train 11:50 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 49 days |
The table below shows live departures for Pisa to Palermo trains for today, Tuesday, August 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4048+ FRECCIAROSSA 9431+ InterCityNotte 1955 | 5:32 PM Pisa Centrale | 15h46 | 9:18 AM Palermo Centrale | 2 transfers | |
FRECCIARGENTO 8591+ InterCityNotte 1959 | 8:38 PM Pisa Centrale | 16h18 | 12:56 PM Palermo Centrale | 1 transfer | |
| Wednesday, August 5 | |||||
Intercity 723+ InterCityNotte 899 | 2:21 AM Pisa Centrale | 16h49 | 7:10 PM Palermo Centrale | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 9503+ Intercity 723 | 4:15 AM Pisa Centrale | 14h55 | 7:10 PM Palermo Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Official public transport app
Palermo Centrale -> Quattro Canti, Palermo
Find answers to the most common questions about traveling from Pisa to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Pisa to Palermo trains use the Pisa Centrale to Palermo Centrale station pair. Use this guide to compare Pisa and Palermo train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Pisa, Aeroporto Galilei Di Pisa is 1 km from Pisa city centre. Check local transport options before travel.
Pisa, Aeroporto Galilei Di Pisa has practical services for this route, including Accessibility.
Accessibility facilities are available at Pisa, Aeroporto Galilei Di Pisa.
Pisa San Rossore is 1 km from Pisa city centre. Public transport options include:
Pisa San Rossore has practical services for this route, including Parking, Dining, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Ristorante pizzeria, SushiKing, Ristorante Cinese Oriente
The ticket office is open 24/7.
Available at Pisa San Rossore: Parking, WC.
Available at Pisa San Rossore: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa San Rossore: Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
Nearby hotels include Rosso di Sera Relais Tuscany, Le Cascine, Camping Village Torre Pendente.
Here are some other resources that might have the information you need