The cheapest and fastest trains from Pisa to Palermo
Cheapest price
$107
Average price
$170
Fastest journey
13 h 46 m
Average duration
15 h 19 m
Trains per day
6
Distance
670 km
The best way to find a cheap train ticket from Pisa to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Palermo will cost around $170 if you buy it on the day, but the cheapest tickets can be found for only $107.
It's difficult to get from Pisa to Palermo without transferring at least once.
Intercity 501 · Intercity 7276:47 AM16h14Pisa Centrale11:01 PMPalermo Centrale$1071One-way1 transfer
FRECCIARGENTO 8583+
Intercity 7277:33 AM15h28Pisa Centrale11:01 PMPalermo Centrale$1341One-way1 transfer
InterCityNotte 899+
Intercity 7232:56 AM16h12Pisa Centrale7:08 PMPalermo Centrale$1371One-way1 transfer
Regionale 18250+
FRECCIAROSSA 9503+
Intercity 7234:15 AM14h53Pisa Centrale7:08 PMPalermo Centrale$1851One-way2 transfers
FRECCIARGENTO 8551+
FRECCIAROSSA 9519+
Intercity 7279:15 AM13h46Pisa Centrale11:01 PMPalermo Centrale$2081One-way2 transfers
FRECCIARGENTO 8551+
FRECCIAROSSA 9519+
Intercity 7279:15 AM13h46Pisa Centrale11:01 PMPalermo Centrale$2081One-way2 transfers
Regionale 18250+
FRECCIAROSSA 9503+
Intercity 7234:15 AM14h53Pisa Centrale7:08 PMPalermo Centrale$1851One-way2 transfers
FRECCIARGENTO 8583+
Intercity 7277:33 AM15h28Pisa Centrale11:01 PMPalermo Centrale$1341One-way1 transfer
InterCityNotte 899+
Intercity 7232:56 AM16h12Pisa Centrale7:08 PMPalermo Centrale$1371One-way1 transfer
Intercity 501 · Intercity 7276:47 AM16h14Pisa Centrale11:01 PMPalermo Centrale$1071One-way1 transfer
Travel Information
Compare bus, train, flight, and ferry for Pisa to Palermo
Omio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from $49. For those with little time consider booking a flight which can get you there in 1h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a ferry costs an average of $49, and a flight costs an average of $21.
Distance: 416 miles (670 km)
Compare train with
| Train | Most popular Flight | Ferry | Bus |
|---|---|---|---|
$130 Average price | $145 Average price | $68 Average price Cheapest | $87 Average price |
16h 9m Average total duration 15h 39m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 20h 49m Average total duration 19h 49m Onboard + 1h 0m Additional time* | 17h 53m Average total duration 17h 23m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions | 0.7 - 1.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular ferry company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Palermo train times
The table below shows live departures for Pisa to Palermo trains for tomorrow, Wednesday, May 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
InterCityNotte 899+ Intercity 723 | 2:56 AM Pisa Centrale | 16h12 | 7:08 PM Palermo Centrale | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 9503+ Intercity 723 | 4:15 AM Pisa Centrale | 14h53 | 7:08 PM Palermo Centrale | 2 transfers | |
Intercity 501 · Intercity 727 | 6:47 AM Pisa Centrale | 16h14 | 11:01 PM Palermo Centrale | 1 transfer | |
FRECCIARGENTO 8583+ Intercity 727 | 7:33 AM Pisa Centrale | 15h28 | 11:01 PM Palermo Centrale | 1 transfer | |
FRECCIARGENTO 8551+ FRECCIAROSSA 9519+ Intercity 727 | 9:15 AM Pisa Centrale | 13h46 | 11:01 PM Palermo Centrale | 2 transfers | |
FRECCIARGENTO 8591+ InterCityNotte 1959 | 8:38 PM Pisa Centrale | 17h05 | 1:43 PM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Palermo by bus, train, flight, or ferry
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How far in advance should I book train tickets from Pisa to Palermo?
Journey information
Overview: Train from Pisa to Palermo
Trains from Pisa to Palermo run on average 7 times per day, taking around 15h 39m. Cheap train tickets for this journey start at $51 (€41) but you can travel from only $21 (€17) by flight.
The earliest train runs at 00:01, the last at 23:40. The fastest train covers the 416 miles (670 km) distance in 14h 55m.
Distance 416 miles (670 km) |
Average train duration 15h 39m |
Cheapest ticket price $51 (€41) |
Trains per day 7 |
Fastest train 14h 55m |
First train 12:01 AM |
Last train 11:40 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Tue |
Best time to book 49 days |
Train companies: Intercity, Intercity Notte, Regionale from Pisa to Palermo trainsIntercity, Intercity Notte, Regionale trains will get you between Pisa and Palermo from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity
Intercity Notte
Regionale
FAQs: Trains from Pisa to Palermo
Find answers to the most common questions about traveling from Pisa to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa to Palermo
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 24/7
- Ristorante pizzeria
- SushiKing
- Ristorante Cinese Oriente
- Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
- Rosso di Sera Relais Tuscany
- Le Cascine
- Camping Village Torre Pendente
- 24/7
- Train lines: REG, RV
Most popular train connections from Pisa
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