- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price on Sep 19
$24
Average ticket price on Sep 19
$28
Fastest journey on Sep 19
4 h 17 m
Average journey duration on Sep 19
4 h 48 m
Trains on Sep 19
8
Distance
204 km
The best way to find a cheap train ticket from Syracuse to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Palermo will cost around $28 if you buy it on the day, but the cheapest tickets can be found for only $24.
It's difficult to get from Syracuse to Palermo without transferring at least once.
Regionale 5516 · Regionale Veloce 5519
Regionale 5502 · Regionale Veloce 5503
Regionale 5380 · Regionale Veloce 5491
Regionale 5382 · Regionale 21507 · Regionale Veloce 5511
Regionale 5386 · Regionale Veloce 5513
Regionale 5386 · Regionale Veloce 5513
Regionale 5516 · Regionale Veloce 5519
Regionale 5502 · Regionale Veloce 5503
Intercity 734+
Regionale Veloce 5491
Regionale 5380 · Regionale Veloce 5491Omio recommends booking the bus as it is the most popular option from Syracuse to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of $32 For those with little time, consider booking a bus, which has an average total journey time of 4h 10m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a train costs an average of $32, while a bus costs an average of $35.
Distance: 126 miles (204 km)
| Train | Most popular Bus |
|---|---|
$32 Average price Cheapest | $35 Average price |
5h 31m Average total duration 5h 1m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Palermo:
A train is $4 less than a bus for this route with tickets for a bus from Syracuse to Palermo costing on average $35.
Other travel options to Palermo take longer:
Train takes on average 5h 1m.
The table below shows live departures for Syracuse to Palermo trains for today, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 5502 · Regionale Veloce 5503 | 5:49 AM Syracuse station | 4h40 | 10:29 AM Palermo Centrale | 1 transfer | |
Regionale 5380 · Regionale Veloce 5491 | 6:40 AM Syracuse station | 5h49 | 12:29 PM Palermo Centrale | 1 transfer | |
Intercity 734+ Regionale Veloce 5491 | 7:43 AM Syracuse station | 4h46 | 12:29 PM Palermo Centrale | 1 transfer | |
Regionale 5382 · Regionale 21507 · Regionale Veloce 5511 | 8:49 AM Syracuse station | 7h40 | 4:29 PM Palermo Centrale | 2 transfers | |
Regionale 5382 · Regionale 5361 | 8:49 AM Syracuse station | 6h38 | 3:27 PM Palermo Centrale | 1 transfer | |
Intercity 724+ Regionale Veloce 5511 | 10:25 AM Syracuse station | 6h04 | 4:29 PM Palermo Centrale | 1 transfer | |
Regionale 5386 · Regionale Veloce 5513 | 2:12 PM Syracuse station | 4h17 | 6:29 PM Palermo Centrale | 1 transfer | |
Regionale 5516 · Regionale Veloce 5519 | 4:00 PM Syracuse station | 4h29 | 8:29 PM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Syracuse to Palermo run on average 7 times per day, taking around 5h 1m. Cheap train tickets for this journey start at $24 but you can travel from only $18 by bus.
The earliest train runs at 03:17, the last at 20:25. The fastest train covers the 126 miles (204 km) distance in 3h 42m.
Distance 126 miles (204 km) |
Average train duration 5h 1m |
Cheapest ticket price $24 |
Trains per day 7 |
Fastest train 3h 42m |
First train 3:17 AM |
Last train 8:25 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 42 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Official public transport app
Palermo Centrale -> Quattro Canti, Palermo
Find answers to the most common questions about traveling from Syracuse to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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