Travel Information
Compare train, bus, and flight for Lyon to Palermo
Omio recommends booking the flight as it is the most popular option from Lyon to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $89. For those with little time consider booking a flight which can get you there in 2h 41m. The ticket price range depends on the travel mode: a bus costs an average of $89, and a flight costs an average of $93.
Distance: 684 miles (1102 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
$266 Average price | $313 Average price | $173 Average price Cheapest |
21h 52m Average total duration 21h 22m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* | 28h 40m Average total duration 28h 10m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Lyon to Palermo by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon to Palermo trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of SNCF to find the best option for your trip from Lyon to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Palermo.
Journey information
Overview: Train from Lyon to Palermo
Trains from Lyon to Palermo run on average 1 times per day, taking around 21h 22m. Cheap train tickets for this journey start at $179 (€145) but you can travel from only $89 (€72) by bus.
The earliest train runs at 05:46, the last at 21:10. The fastest train covers the 684 miles (1102 km) distance in 23h 35m.
Distance 684 miles (1102 km) |
Average train duration 21h 22m |
Cheapest ticket price $179 (€145) |
Trains per day 1 |
Fastest train 23h 35m |
First train 05:46 |
Last train 21:10 |
Cheapest month Jan |
Cheapest day Wed |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Mon |
Least busy day Sun |
Best day to book ahead 42 days |
Train companies: Intercity Notte, SNCF from Lyon to Palermo trainsIntercity Notte, SNCF trains will get you between Lyon and Palermo from $89 (€72). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
SNCF
FAQs: Trains from Lyon to Palermo
Find answers to the most common questions about traveling from Lyon to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon to Palermo
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
More options for your journey from Lyon to Palermo
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