- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
Omio recommends booking the flight as it is the most popular option from Lyon to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $99. For those with little time consider booking a flight which can get you there in 2h 41m. The ticket price range depends on the travel mode: a bus costs an average of $99, and a flight costs an average of $53.
Distance: 684 miles (1102 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$253 Average price | $268 Average price | $173 Average price Cheapest | $323 Average price (fuel + tolls) |
24h 41m Average total duration 24h 11m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* | 28h 52m Average total duration 28h 22m Onboard + 30m Additional time* | 19h 26m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Palermo:
A bus is $81 (€66) less than a train for this route with tickets for a train from Lyon to Palermo costing on average $253 (€207).
A bus is $95 (€78) less than a flight for this route with tickets for a flight from Lyon to Palermo costing on average $268 (€219).
Other travel options to Palermo take longer:
Train takes on average 24h 11m.
Bus takes on average 28h 22m.
Tickets start at around $253 (€207) compared to roughly $323 (€264) in fuel and tolls — a saving of about $69 (€57). The journey takes 24h 11m versus 19h 26m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Lyon to Palermo trains for today, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:31 AM Lyon | 23h37 | 7:08 AM Palermo | 0 transfersDirect | |
![]() | 8:31 AM Lyon | 23h40 | 8:11 AM Palermo | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Lyon to Palermo run on average 1 times per day, taking around 24h 11m. Cheap train tickets for this journey start at $191 (€156) but you can travel from only $53 (€44) by flight.
The earliest train runs at 05:46, the last at 21:10. The fastest train covers the 684 miles (1102 km) distance in 23h 37m.
Distance 684 miles (1102 km) |
Average train duration 24h 11m |
Cheapest ticket price $191 (€156) |
Trains per day 1 |
Fastest train 23h 37m |
First train 5:46 AM |
Last train 9:10 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 42 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
One of Sicily's most important archaeological museums, with Punic, Greek and Roman collections and notable sculpture fragments.
Historic noble residence preserved with original furnishings, offering a vivid look at aristocratic life in Palermo.
Energetic historic district centered on Palermo's most famous street market, full of everyday local life and vivid street scenes.
Striking central square framed by historic buildings and the famous fountain, a key stop in the old town.
One of Palermo's main historic streets, largely pedestrianized and lined with landmarks, shops and lively urban scenes.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. Palermo is famous for its round arancine and strong street-food tradition.
A classic Palermo street sandwich made with veal spleen and lung, often topped with caciocavallo or ricotta. It is one of the city's most iconic local bites.
Chickpea fritters, usually served in a sesame bread roll. They are a beloved Palermo snack and a staple of the city's historic friggitorie.
Well-regarded restaurant near the historic center serving refined Sicilian cuisine with local ingredients in an elegant but relaxed atmosphere.
Popular central spot for approachable Sicilian cooking, including pasta and regional classics, with a casual and lively atmosphere.
Established seafood-focused trattoria appreciated for traditional Palermo and Sicilian dishes in a classic local dining room.
Moderate by Italian standards: street food is cheap, while central hotels and tourist restaurants cost more.
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; about 5-10% for very good restaurant service. Taxis are usually rounded up.
Official public transport app
Palermo Centrale, Palermo -> Quattro Canti, Palermo
Find answers to the most common questions about traveling from Lyon to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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