The cheapest and fastest trains from Milan Centrale to Palermo
Cheapest price
$146
Average price
$206
Fastest journey
14 h 25 m
Average duration
18 h 34 m
Trains per day
4
Distance
889 km
The best way to find a cheap train ticket from Milan Centrale to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Palermo will cost around $206 if you buy it on the day, but the cheapest tickets can be found for only $146.
Of the 4 trains that leave Milan Centrale for Palermo on Mon, Dec 22, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct trains cover the 889 km distance in an average of 18 h 34 m but if you time it right, some trains will get you there in just 14 h 25 m .
On Mon, Dec 22 the slowest trains will take 22 h 43 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Milan Centrale - PalermoCompare Intercity Notte, Intercity, Italo



Travel Information
Compare train, bus, flight, and ferry for Milan Centrale to Palermo
Omio recommends booking the train as it is the most popular option from Milan Centrale to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €57. For those with little time consider booking a flight which can get you there in 1h 46m. The ticket price range depends on the travel mode: a ferry costs an average of €57, and a train costs an average of €60.
Distance: 552 miles (889 km)
Compare train with
Most popular Train | Flight | Bus | Ferry |
|---|---|---|---|
€129 Average price | €85 Average price | €109 Average price | €71 Average price Cheapest |
15h 46m Average total duration 15h 16m Onboard + 30m Additional time* | 4h 46m Average total duration Fastest 1h 46m Onboard + 3h 0m Additional time* | 22h 12m Average total duration 21h 42m Onboard + 30m Additional time* | 20h 50m Average total duration 19h 50m Onboard + 1h 0m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Palermo train times
The table below shows live departures for Milan Centrale to Palermo trains for today, Sunday, December 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:15 AM Milan Centrale | 25h07 | 7:22 AM Palermo | 0 transfersDirect | |
![]() | 6:10 PM Milan Centrale | 22h15 | 4:25 PM Palermo | 0 transfersDirect | |
![]() | 7:20 PM Milan Centrale | 16h12 | 11:32 AM Palermo | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
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Dec 29
Dec 30
Dec 31
Jan 01
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Jan 04
Why should you book Milan Centrale to Palermo trains with Omio?
Intercity Notte as well as Intercity, Italo and Frecciargento offer trains services from Milan Centrale to Palermo. Omio is an official ticket reseller for all your travel options from Milan Centrale to Palermo.
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo and Frecciargento to find the best option for your trip from Milan Centrale to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan Centrale to Palermo.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Intercity Notte tickets can be bought on Intercity Notte's website or third party sellers, Omio allows you to compare with the likes of Intercity, Italo and Frecciargento to help you choose the right option for your journey from Milan Centrale to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan Centrale to Palermo.
Journey information
Overview: Train from Milan Centrale to Palermo
Trains from Milan Centrale to Palermo run on average 6 times per day, taking around 15h 16m. Cheap train tickets for this journey start at $75 (€60) but you can travel from only $29 (€23) by flight.
There are 1 trains per day. The earliest train runs at 03:20, the last at 20:25. The fastest train covers the 552 miles (889 km) distance in 13h 42m.
Distance 552 miles (889 km) |
Average train duration 15h 16m |
Cheapest ticket price $75 (€60) |
Trains per day 6 |
Direct trains 1 |
Fastest train 13h 42m |
First train 03:20 |
Last train 20:25 |
Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Milan Centrale to Palermo trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Milan Centrale and Palermo from $29 (€23). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Italo
Frecciargento
Frecciarossa
FAQs: Trains from Milan Centrale to Palermo
Find answers to the most common questions about traveling from Milan Centrale to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Palermo
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Palermo
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