Travel Information
Compare bus, train, flight, and ferry for Pisa to Palermo
Omio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of $37 For those with little time, consider booking a flight, which has an average total journey time of 4h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a train costs an average of $37, while a flight costs an average of $265.
Distance: 416 miles (670 km)
Compare flight with
Most popular Flight | Train | Ferry | Bus |
|---|---|---|---|
$265 Average price | $37 Average price Cheapest | $56 Average price | $103 Average price |
4h 5m Average total duration Fastest 2h 5m Onboard + 2h 0m Additional time* | 16h 14m Average total duration 15h 44m Onboard + 30m Additional time* | 20h 41m Average total duration 19h 41m Onboard + 1h 0m Additional time* | 20h 37m Average total duration 20h 7m Onboard + 30m Additional time* |
- CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions | 0.7 - 1.7kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Pisa to Palermo
Compare the available ways to get from Pisa to Palermo, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Pisa to Palermo:
A train is $19 less than a ferry for this route with tickets for a ferry from Pisa to Palermo costing on average $56.
A train is $66 less than a bus for this route with tickets for a bus from Pisa to Palermo costing on average $103.
A train is $228 less than a flight for this route with tickets for a flight from Pisa to Palermo costing on average $265.
Other travel options to Palermo take longer:
Train takes on average 16h 14m.
Bus takes on average 20h 37m.
Ferry takes on average 20h 41m.
Travel optionsfrom Pisa to Palermo
How to get from Pisa to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Palermo is by taking a flight because it’s the best combination of price and speed.
FR 84507:25 AM 1h20 Pisa International Airport 8:45 AM Palermo Airport $22 1 One-way 0 transfers
Cheapest
FR 84507:25 AM 1h20 Pisa International Airport 8:45 AM Palermo Airport $22 1 One-way 0 transfers
Fastest
FR 84507:25 AM 1h20 Pisa International Airport 8:45 AM Palermo Airport $22 1 One-way 0 transfers
Other options
Intercity 501 · Intercity 950576:47 AM 16h11 Pisa Centrale 10:58 PM Palermo Centrale $96 1 One-way 1 transfer
InterCityNotte 899+
Intercity 7232:21 AM 16h43 Pisa Centrale 7:04 PM Palermo Centrale $96 1 One-way 1 transfer
FRECCIARGENTO 8583+
Intercity 950577:33 AM 15h25 Pisa Centrale 10:58 PM Palermo Centrale $115 1 One-way 1 transfer
FlixBus · FlixBus5:10 PM 22h05 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) $68 1 One-way 1 transfer
FlixBus · FlixBus · FlixBus7:15 AM 27h45 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) $71 1 One-way 2 transfers
W4662412:35 PM 1h25 Pisa International Airport 2:00 PM Palermo Airport $37 1 One-way 0 transfers
FR 62566:20 PM 1h20 Pisa International Airport 7:40 PM Palermo Airport $64 1 One-way 0 transfers
GL876:30 PM 19h30 Livorno (Terminal Grimaldi) 2:00 PM Port of Palermo $58 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Palermo.

This is compared to other travel options from Pisa to Palermo:
A train is $19 less than a ferry for this route with tickets for a ferry from Pisa to Palermo costing on average $56.
A train is $66 less than a bus for this route with tickets for a bus from Pisa to Palermo costing on average $103.
A train is $228 less than a flight for this route with tickets for a flight from Pisa to Palermo costing on average $265.
Other travel options to Palermo take longer:
Train takes on average 16h 14m.
Bus takes on average 20h 37m.
Ferry takes on average 20h 41m.
- Around 31 trains per day.
- Around 3 flights per day.
- Around 3 buses per day.
- Around 1 ferries per day.
However, we recommend checking specific travel dates for your route between Pisa and Palermo as scheduled services by bus, train, flight, and ferry can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Palermo Airport.
- Trains mostly depart from Pisa Centrale and arrive in Palermo Centrale.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Ferries mostly depart from Livorno (Terminal Grimaldi) and arrive in Port of Palermo.
- Travel with FlixBus to go to Palermo by bus.
- Travel with Intercity Notte, Intercity to go to Palermo by train.
- Travel with Malta Air, Lufthansa, British Airways, Helvetic Airways, Air Baltic, Ryanair to go to Palermo by flight.
- Travel with Grimaldi to go to Palermo by ferry.
- 3 direct flights per day with Malta Air, Ryanair.
- 1 direct ferries per day with Grimaldi.
Travelling from Pisa to Palermo: related information
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