Travel Information
Compare bus, train, flight, and ferry for Pisa to Palermo
Omio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from $50. For those with little time consider booking a flight which can get you there in 1h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a ferry costs an average of $50, and a flight costs an average of $22.
Distance: 416 miles (670 km)
Compare flight with
Most popular Flight | Train | Ferry | Bus |
|---|---|---|---|
$146 Average price | $131 Average price | $68 Average price Cheapest | $88 Average price |
4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 16h 9m Average total duration 15h 39m Onboard + 30m Additional time* | 20h 49m Average total duration 19h 49m Onboard + 1h 0m Additional time* | 17h 53m Average total duration 17h 23m Onboard + 30m Additional time* |
- CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions | 0.7 - 1.7kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Palermo
How to get from Pisa to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Palermo is by taking a flight because it’s the best combination of price and speed.
FR 62566:20 AM1h20Pisa International Airport7:40 AMPalermo Airport$281One-way0 transfers
Cheapest
FR 62566:20 AM1h20Pisa International Airport7:40 AMPalermo Airport$281One-way0 transfers
Fastest
FR 62566:20 AM1h20Pisa International Airport7:40 AMPalermo Airport$281One-way0 transfers
Other options
InterCityNotte 899+
Intercity 7232:56 AM16h12Pisa Centrale7:08 PMPalermo Centrale$1421One-way1 transfer
Intercity 501 · Intercity 7276:47 AM16h14Pisa Centrale11:01 PMPalermo Centrale$1491One-way1 transfer
FRECCIARGENTO 8583+
Intercity 7277:33 AM15h28Pisa Centrale11:01 PMPalermo Centrale$1781One-way1 transfer
FlixBus · FlixBus5:25 PM21h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$791One-way1 transfer
FlixBus · FlixBus12:00 PM23h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$1001One-way1 transfer
FlixBus · FlixBus · FlixBus6:05 AM28h55Pisa, Aeroporto Parcheggio Aurelia11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$1151One-way2 transfers
FR 848611:30 AM1h20Pisa International Airport12:50 PMPalermo Airport$791One-way0 transfers
FR 84503:25 PM1h20Pisa International Airport4:45 PMPalermo Airport$1221One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Palermo.

This is compared to other travel options from Pisa to Palermo:
A ferry is $19 (€15) less than a bus for this route with tickets for a bus from Pisa to Palermo costing on average $88 (€70).
A ferry is $63 (€50) less than a train for this route with tickets for a train from Pisa to Palermo costing on average $131 (€105).
A ferry is $77 (€62) less than a flight for this route with tickets for a flight from Pisa to Palermo costing on average $146 (€116).
Other travel options to Palermo take longer:
Train takes on average 15h 39m.
Bus takes on average 17h 23m.
Ferry takes on average 19h 49m.
- Around 7 trains per day.
- Around 3 flights per day.
- Around 3 buses per day.
- Around 1 ferries per day.
However, we recommend checking specific travel dates for your route between Pisa and Palermo as scheduled services by bus, train, flight, and ferry can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Palermo Airport.
- Trains mostly depart from Pisa Centrale and arrive in Palermo Centrale.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Ferries mostly depart from Port of Livorno and arrive in Port of Palermo.
- Travel with Intercity, Intercity Notte, Regionale to go to Palermo by train.
- Travel with FlixBus, BlaBlaCar, Curcio Viaggi to go to Palermo by bus.
- Travel with Ryanair, Malta Air, Volotea to go to Palermo by flight.
- Travel with Grimaldi to go to Palermo by ferry.
- 0 direct buses per day with BlaBlaCar.
- 3 direct flights per day with Ryanair, Malta Air.
Travelling from Pisa to Palermo: related information
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