- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Pisa to Palermo
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$72
Average ticket price on Sep 19
$76
Fastest journey on Sep 19
21 h 35 m
Average journey duration on Sep 19
1 d 7 m
Buses on Sep 19
3
Distance
670 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Palermo will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $72.
Fast buses
It's difficult to get from Pisa to Palermo without transferring at least once.
FlixBus · FlixBus1:25 PM21h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$721One-way1 transfer- FlixBus · FlixBus5:25 PM21h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$781One-way1 transfer
- FlixBus · FlixBus · FlixBus6:05 AM28h55Pisa (Pisamover via San Giusto/Aurelia)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$791One-way2 transfers
- FlixBus · FlixBus1:25 PM21h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$721One-way1 transfer
- FlixBus · FlixBus5:25 PM21h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$781One-way1 transfer
- FlixBus · FlixBus · FlixBus6:05 AM28h55Pisa (Pisamover via San Giusto/Aurelia)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$791One-way2 transfers
Travel Information
Compare bus, train, flight, and ferry for Pisa to Palermo
Omio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of $29 For those with little time, consider booking a flight, which has an average total journey time of 3h 53m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a train costs an average of $29, while a flight costs an average of $256.
Distance: 416 miles (670 km)
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
$126 Average price | $256 Average price | $29 Average price Cheapest | $63 Average price |
20h 50m Average total duration 20h 20m Onboard + 30m Additional time* | 3h 53m Average total duration Fastest 1h 53m Onboard + 2h 0m Additional time* | 16h 17m Average total duration 15h 47m Onboard + 30m Additional time* | 20h 44m Average total duration 19h 44m Onboard + 1h 0m Additional time* |
0.7 - 1.7kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company |  Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Pisa to Palermo is a train with an average price of $29.
This is compared to other travel options from Pisa to Palermo:
A train is $34 less than a ferry for this route with tickets for a ferry from Pisa to Palermo costing on average $63.
A train is $97 less than a bus for this route with tickets for a bus from Pisa to Palermo costing on average $126.
A train is $227 less than a flight for this route with tickets for a flight from Pisa to Palermo costing on average $256.
The fastest way to travel from Pisa to Palermo is by flight with an average journey time of 1h 53m.
Other travel options to Palermo take longer:
Train takes on average 15h 47m.
Ferry takes on average 19h 44m.
Bus takes on average 20h 20m.
It's helpful to compare your options as there are 4 ways to travel between Pisa and Palermo including taking a bus, train, flight, and ferry.
We recommend using the flight as it is the most popular way to get from Pisa to Palermo among Omio's users.
Pisa to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:05AM | Arrival Time 11:00AM | Duration 28h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 11:00AM | Duration 27h45 | Departure days Wed | Cheapest price $65 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 11:00AM | Duration 23h00 | Departure days Thu | Cheapest price $59 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 11:00AM | Duration 21h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 03:15PM | Duration 22h05 | Departure days Tue, Wed | Cheapest price $40 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 03:15PM | Duration 21h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $67 |
Live departures
Pisa to Palermo bus times
The table below shows live departures for Pisa to Palermo buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h35 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus · FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h50 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| Saturday, September 19 | |||||
| FlixBus · FlixBus · FlixBus | 6:05 AM Pisa (Pisamover via San Giusto/Aurelia) | 28h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Palermo by bus, train, flight, or ferry
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Sep 19
Sep 19
Sun
Sep 20
Sep 20
Mon
Sep 21
Sep 21
Tue
Sep 22
Sep 22
Wed
Sep 23
Sep 23
Thu
Sep 24
Sep 24
Fri
Sep 25
Sep 25
Sat
Sep 26
Sep 26
Sun
Sep 27
Sep 27
Mon
Sep 28
Sep 28
Tue
Sep 29
Sep 29
Wed
Sep 30
Sep 30
Thu
Oct 01
Oct 01
Fri
Oct 02
Oct 02
Sat
Oct 03
Oct 03
Sun
Oct 04
Oct 04
Mon
Oct 05
Oct 05
Tue
Oct 06
Oct 06
Wed
Oct 07
Oct 07
Thu
Oct 08
Oct 08
Fri
Oct 09
Oct 09
Why should you book Pisa to Palermo buses with Omio?
FlixBus operates all buses services from Pisa to Palermo.
Omio is an official ticket reseller for all your travel options from Pisa to Palermo.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train, flight and ferry to ensure you get the best deal for traveling from Pisa to Palermo.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train, flight and ferry to find the ideal travel option from Pisa to Palermo.
Journey information
Overview: Bus from Pisa to Palermo
ItalyItaly
Buses from Pisa to Palermo run on average 3 times per day, taking around 20h 20m. Cheap bus tickets for this journey start at $48 but you can travel from only $11 by train.
The earliest bus runs at 01:38, the last at 23:30. The fastest bus covers the 416 miles (670 km) distance in 18h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $11
Distance 416 miles (670 km) |
Average bus duration 20h 20m |
Cheapest ticket price $48 |
Buses per day 3 |
Fastest bus 18h 0m |
First bus 1:38 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $11
Bus providers: FlixBus from Pisa to PalermoYou can travel by bus between Pisa to Palermo with FlixBus for as low as $25. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
18h 0m
Cheapest FlixBus Price
$48
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Palermo
Things to do in Palermo
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
- Recommended
Palazzo Mirto
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
- Recommended
Steri Museum
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
- Must visit
Via Vittorio Emanuele
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
- Must visit
Via Maqueda
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
- Recommended
Albergheria
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Arancina
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Pane con la Milza
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta con le Sarde
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
I Pupi
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Osteria Ballarò
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Nni Franco U Vastiddaru
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Euro (€)
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Average meal costs
- Budget
- €8-12 for street food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
FAQs: Bus from Pisa to Palermo
Find answers to the most common questions about traveling from Pisa to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Palermo can start from as little as $48 when you book in advance. The average bus ticket price for Pisa to Palermo is $126 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Palermo is 18h 0m to travel the 416 miles (670 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Palermo leaves at 1:38 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Palermo leaves at 11:30 PM.
There are 3 buses a day from Pisa to Palermo which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Palermo, you can count on FlixBus for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Pisa and Palermo and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia), Lucca, Stazione FS . When arriving in Palermo , you can end your journey in bus stations like Palermo, Via Tommaso Fazello (Terminal Bus) .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Palermo, Via Tommaso Fazello (Terminal Bus), located 1 away from the city centre.
A trip to Palermo from Pisa is worth doing but not as a day trip with a journey time of 18h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Palermo is March.
It's helpful to compare your options as there are 4 ways to travel between Pisa and Palermo including taking a bus, train, flight, and ferry.
Yes, there are bathrooms on board the bus from Pisa to Palermo for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Pisa to Palermo:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Palermo are:
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Whether you can cancel your bus ticket from Pisa to Palermo depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Palermo:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Palermo:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Palermo. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Palermo with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Palermo with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Palermo with the following bus company: FlixBus.
Since both Pisa and Palermo are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Palermo among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Palermo
Most Pisa to Palermo buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Pisa and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pisa
Arrival bus stations in Palermo
Which Pisa station do buses to Palermo leave from?
Buses from Pisa to Palermo leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, Italy
City-centre transport
Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Bus21, E24, 1+ · 12m · $1 · every ~10 min
1+, 21 · 14m · $1 · every ~9 min
1+ · 24m · $2 · every ~9 min
21 · 30m · $2
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi and ATMs
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Tickets and information
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Parking, taxis and toilets
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Bike and car services
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, Italy
City-centre transport
Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Bus15 · 5m · $1 · every ~3 min
15 · 7m · $1 · every ~3 min
15 · 9m · $1 · every ~3 min
Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Tickets and information
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Parking, taxis and toilets
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Most popular bus connections from Pisa
More options for your journey from Pisa to Palermo
Here are some other resources that might have the information you need
Most popular buses to and from Palermo and Pisa
Most popular bus connections to Palermo
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
