- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
€104
Average price
€119
Fastest journey
22 h 5 m
Average duration
23 h 43 m
Buses per day
2
Distance
670 km
The best way to find a cheap bus ticket from Pisa to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Palermo will cost around €119 if you buy it on the day, but the cheapest tickets can be found for only €104.
It's difficult to get from Pisa to Palermo without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €39. For those with little time consider booking a flight which can get you there in 1h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a ferry costs an average of €39, and a train costs an average of €55.
Distance: 416 miles (670 km)
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
€63 Average price | €102 Average price | €111 Average price | €49 Average price Cheapest |
17h 52m Average total duration 17h 22m Onboard + 30m Additional time* | 4h 24m Average total duration Fastest 1h 24m Onboard + 3h 0m Additional time* | 16h 9m Average total duration 15h 39m Onboard + 30m Additional time* | 20h 52m Average total duration 19h 52m Onboard + 1h 0m Additional time* |
0.7 - 1.7kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Palermo:
A ferry is €13 less than a bus for this route with tickets for a bus from Pisa to Palermo costing on average €63.
A ferry is €52 less than a flight for this route with tickets for a flight from Pisa to Palermo costing on average €102.
A ferry is €62 less than a train for this route with tickets for a train from Pisa to Palermo costing on average €111.
Other travel options to Palermo take longer:
Train takes on average 15h 39m.
Bus takes on average 17h 22m.
Ferry takes on average 19h 52m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:05AM | Arrival Time 11:00AM | Duration 28h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price €99 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 11:10PM | Duration 14h00 | Departure days Fri | Cheapest price €110 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 11:00AM | Duration 25h20 | Departure days Wed | Cheapest price €104 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 11:00AM | Duration 23h00 | Departure days Thu | Cheapest price €111 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 11:00AM | Duration 21h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €148 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 03:15PM | Duration 22h05 | Departure days Tue, Wed | Cheapest price €113 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 03:15PM | Duration 21h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €112 |
The table below shows live departures for Pisa to Palermo buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:05 AM Pisa (Pisamover via San Giusto/Aurelia) | 28h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h35 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h05 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Palermo run on average 3 times per day, taking around 17h 22m. Cheap bus tickets for this journey start at €26 but you can travel from only €17 by flight.
The earliest bus runs at 01:38, the last at 23:30. The fastest bus covers the 416 miles (670 km) distance in 20h 30m.
Distance 416 miles (670 km) |
Average bus duration 17h 22m |
Cheapest ticket price €26 |
Buses per day 3 |
Fastest bus 20h 30m |
First bus 1:38 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 42 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Pisa to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Pisa to Palermo buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Pisa and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need