The cheapest and fastest buses from Pisa to Palermo
Cheapest price
$190
Average price
$214
Fastest journey
21 h
Average duration
23 h 57 m
Buses per day
3
Distance
670 km
The best way to find a cheap bus ticket from Pisa to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Palermo will cost around $214 if you buy it on the day, but the cheapest tickets can be found for only $190.
It's difficult to get from Pisa to Palermo without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare train, bus, flight, and ferry for Pisa to Palermo
Omio recommends booking the flight as it is the most popular option from Pisa to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €40. For those with little time consider booking a flight which can get you there in 1h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a ferry costs an average of €40, and a flight costs an average of €25.
Distance: 416 miles (670 km)
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
€101 Average price | €125 Average price | €119 Average price | €56 Average price Cheapest |
17h 55m Average total duration 17h 25m Onboard + 30m Additional time* | 4h 24m Average total duration Fastest 1h 24m Onboard + 3h 0m Additional time* | 16h 7m Average total duration 15h 37m Onboard + 30m Additional time* | 20h 49m Average total duration 19h 49m Onboard + 1h 0m Additional time* |
0.7 - 1.7kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Pisa to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 11:00AM | Duration 29h15 | Departure days Mon, Tue, Fri, Sun | Cheapest price $142 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 11:10PM | Duration 13h10 | Departure days Wed | Cheapest price $99 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 11:00AM | Duration 21h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 02:25PM | Duration 21h30 | Departure days Tue, Wed | Cheapest price $177 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 02:25PM | Duration 21h00 | Departure days Mon, Sun | Cheapest price $190 |
Live departures
Pisa to Palermo bus times
The table below shows live departures for Pisa to Palermo buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:30 PM Pisa | 35h30 | 9:00 AM Palermo | 0 transfersDirect | |
| Sunday, December 21 | |||||
FlixBus · FlixBus · FlixBus | 4:45 AM Pisa, Aeroporto Parcheggio Aurelia | 29h15 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus | 12:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h35 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 4:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h00 | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Dec 30
Dec 31
Jan 01
Jan 02
Jan 03
Jan 04
Jan 05
Jan 06
Jan 07
Jan 08
Jan 09
Jan 10
Journey information
Overview: Bus from Pisa to Palermo
Buses from Pisa to Palermo run on average 3 times per day, taking around 17h 25m. Cheap bus tickets for this journey start at $60 (€48) but you can travel from only $31 (€25) by flight.
The earliest bus runs at 02:18, the last at 23:30. The fastest bus covers the 416 miles (670 km) distance in 20h 55m.
Distance 416 miles (670 km) |
Average bus duration 17h 25m |
Cheapest ticket price $60 (€48) |
Buses per day 3 |
Fastest bus 20h 55m |
First bus 02:18 |
Last bus 23:30 |
Bus providers: FlixBus, BlaBlaCar, Curcio Viaggi from Pisa to PalermoYou can travel by bus between Pisa to Palermo with FlixBus, BlaBlaCar, Curcio Viaggi for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
Curcio Viaggi
FAQs: Bus from Pisa to Palermo
Find answers to the most common questions about traveling from Pisa to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Pisa to Palermo, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Palermo
Most popular bus connections from Pisa
More options for your journey from Pisa to Palermo
Here are some other resources that might have the information you need



