The cheapest and fastest trains from Mannheim to Prague
Cheapest price
$104
Average price
$174
Fastest journey
8 h 44 m
Average duration
8 h 47 m
Trains per day
8
Distance
431 km
The best way to find a cheap train ticket from Mannheim to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mannheim to Prague will cost around $174 if you buy it on the day, but the cheapest tickets can be found for only $104.
It's difficult to get from Mannheim to Prague without transferring at least 3 times.
ICE 372 · ICE 1559 · EC 10177 · EC 177
ICE 374 · ICE 1557 · EC 10175 · EC 175
S 1 · RE 19064 · ICE 535 · RE 3569
ICE 374 · ICE 91+
359
ICE 202 · ICE 621 · RE 3569+
359
S 1 · RE 19064 · ICE 535 · RE 3569
S 38115 · R 19064 · ICE 535 · RE 3569
ICE 202 · ICE 621 · RE 3569+
359
ICE 202 · ICE 621 · RE 3569 · EC 359
ICE 372 · ICE 1559 · EC 10177 · EC 177Travel Information
Compare train, bus, and flight for Mannheim to Prague
Omio recommends booking the train as it is the most popular option from Mannheim to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €131.
Distance: 267 miles (431 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€86 Average price | €45 Average price Cheapest | €169 Average price |
9h 24m Average total duration 8h 54m Onboard + 30m Additional time* | 7h 3m Average total duration 6h 33m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mannheim to Prague train times
The table below shows live departures for Mannheim to Prague trains for today, Friday, December 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 1557 · EC 10175 · EC 175 | On time 7:02 AM Mannheim Hbf | 9h21 | 4:23 PM Prague hlavní nádraží | 2 transfers | |
ICE 1557 · BUS 10175 · EC 175 | On time 7:02 AM Mannheim Hbf | 9h21 | 4:23 PM Prague hlavní nádraží | 2 transfers | |
ICE 374 · ICE 1557 · EC 10175 · EC 175 | On time 7:32 AM Mannheim Hbf | 8h51 | 4:23 PM Prague hlavní nádraží | 3 transfers | |
ICE 374 · ICE 1557 · BUS 10175 · EC 175 | On time 7:32 AM Mannheim Hbf | 8h51 | 4:23 PM Prague hlavní nádraží | 3 transfers | |
ICE 374 · ICE 91+ 359 | On time 7:32 AM Mannheim Hbf | 9h50 | 5:22 PM Prague hlavní nádraží | 2 transfers | |
ICE 202 · ICE 621 · RE 3569 · EC 359 | On time 8:35 AM Mannheim Hbf | 8h47 | 5:22 PM Prague hlavní nádraží | 3 transfers | |
ICE 202 · ICE 621 · RE 3569+ 359 | On time 8:35 AM Mannheim Hbf | 8h47 | 5:22 PM Prague hlavní nádraží | 3 transfers | |
S 1 · RE 19064 · ICE 535 · RE 3569 | 8:38 AM Mannheim Hbf | 8h44 | 5:22 PM Prague hlavní nádraží | 4 transfers | |
S 38115 · R 19064 · ICE 535 · RE 3569 | 8:38 AM Mannheim Hbf | 8h44 | 5:22 PM Prague hlavní nádraží | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mannheim to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 05
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Why should you book Mannheim to Prague trains with Omio?
Deutsche Bahn (EC,ICE,IC,RE) as well as Alex and ÖBB offer trains services from Mannheim to Prague. Omio is an official ticket reseller for all your travel options from Mannheim to Prague.
Why book with Omio vs Deutsche Bahn (EC,ICE,IC,RE)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (EC,ICE,IC,RE), but also compare tickets for the likes of Alex and ÖBB to find the best option for your trip from Mannheim to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (EC,ICE,IC,RE) with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mannheim to Prague.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (EC,ICE,IC,RE) tickets can be bought on Deutsche Bahn (EC,ICE,IC,RE)'s website or third party sellers, Omio allows you to compare with the likes of Alex and ÖBB to help you choose the right option for your journey from Mannheim to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mannheim to Prague.
How far in advance should I book train tickets from Mannheim to Prague?
Journey information
Overview: Train from Mannheim to Prague
Trains from Mannheim to Prague run on average 9 times per day, taking around 8h 54m. Cheap train tickets for this journey start at $55 (€44) but you can travel from only $35 (€28) by bus.
The earliest train runs at 00:30, the last at 23:50. The fastest train covers the 267 miles (431 km) distance in 7h 50m.
Distance 267 miles (431 km) |
Average train duration 8h 54m |
Cheapest ticket price $55 (€44) |
Trains per day 9 |
Fastest train 7h 50m |
First train 00:30 |
Last train 23:50 |
Train companies: Deutsche Bahn, Alex, ÖBB from Mannheim to Prague trainsDeutsche Bahn, Alex, ÖBB trains will get you between Mannheim and Prague from $35 (€28). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alex
ÖBB
FAQs: Trains from Mannheim to Prague
Find answers to the most common questions about traveling from Mannheim to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mannheim to Prague
- Monday: 06:00 - 21:00
- Tuesday: 06:00 - 21:00
- Wednesday: 06:00 - 21:00
- Thursday: 06:00 - 21:00
- Friday: 06:00 - 21:00
- Saturday: 08:00 - 20:30
- Sunday: 08:00 - 20:30
- Safran Persisch-Afghanische Spezialitäten
- Corner
- Liman Döner
- Kaschmir-Tandoori
- Central
- Leonardo Hotel Mannheim City Center
- InterCityHotel Mannheim
- City Hotel
- Restaurant Tennisklause
- Istanbul
- Pasta Bar
- Pizzeria Corona
- Corner
- Brasserie Bernstein
- Liman Döner
- Uzun Imbiss-Bäckerei
- Best Western Hotel Mannheim City
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Most popular train connections from Mannheim
More options for your journey from Mannheim to Prague
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