How to travel from Mannheim to Prague

Fri, Mar 06
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Travel by train, bus, flight with
FlixBus
Alex
Lufthansa
Deutsche Bahn
České dráhy
1,000+ more
FlixBus
Alex
Lufthansa
Deutsche Bahn
České dráhy
1,000+ more
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Travel Information

Compare train, bus, and flight for Mannheim to Prague

Omio recommends booking the train as it is the most popular option from Mannheim to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $31. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $31, and a flight costs an average of $155.

Distance: 267 miles (431 km)

Compare train with

Most popular
Train
Bus
Flight

$111

Average price

$55

Average price

Cheapest

$211

Average price

9h 40m

Average total duration

9h 10m

Onboard

+

30m

Additional time*

7h 2m

Average total duration

6h 32m

Onboard

+

30m

Additional time*

5h 2m

Average total duration

Fastest

2h 2m

Onboard

+

3h 0m

Additional time*

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.1kg

CO2 emissions

1.3 - 2.6kg

CO2 emissions

Alex

Most popular train company

FlixBus

Most popular bus company

Lufthansa

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Travel options
from Mannheim to Prague

How to get from Mannheim to Prague by train, bus or flight.

Our recommendation

bus

The best way to travel from Mannheim to Prague is by taking a bus because it’s the best combination of price and speed.

FlixBusFlixBus
05:20AM7h25
Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
12:45PMPraha, Na Knížecí
$641One-way
0 transfers

Cheapest

FlixBusFlixBus
05:20AM7h25
Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
12:45PMPraha, Na Knížecí
$641One-way
0 transfers

Fastest

CondorDE4407
02:15PM1h00
Frankfurt am Main Airport
03:15PMPrague Vaclav Havel Airport
$2521One-way
0 transfers

Other options

České dráhyICE 692 · IC 2443 · rj 383
09:29AM7h56
Mannheim Hbf
05:25PMPrague hlavní nádraží
$1691One-way
2 transfers
Deutsche BahnICE 692 · IC 2443 · RJ 383
09:29AM7h56
Mannheim Hbf
05:25PMPrague hlavní nádraží
$2241One-way
2 transfers
Deutsche BahnICE 513+Alex359
09:33AM8h48
Mannheim Hbf
06:21PMPrague hlavní nádraží
$2401One-way
1 transfer
FlixBusFlixBus
05:20AM7h45
Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
01:05PMPraha, ÚAN Florenc
$641One-way
0 transfers
FlixBusFlixBus
03:25AM6h40
Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
10:05AMPraha, Na Knížecí
$641One-way
0 transfers
FlixBusFlixBus
03:25AM7h10
Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
10:35AMPraha, ÚAN Florenc
$641One-way
0 transfers
Deutsche BahnICE 616+CondorDE4407
06:34AM8h41
Mannheim Hbf
03:15PMPrague Vaclav Havel Airport
$3221One-way
1 transfer
Deutsche BahnICE 218+CondorDE4411
03:55PM5h15
Mannheim Hbf
09:10PMPrague Vaclav Havel Airport
$3351One-way
1 transfer
Deutsche BahnICE 106+CondorDE4411
03:33PM5h37
Mannheim Hbf
09:10PMPrague Vaclav Havel Airport
$3351One-way
1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Mannheim to Prague

The Best Way According to our Users

If you want to travel from Mannheim to Prague there are several options available to you. For this route, however, 100,00% of our customers choose the bus as their preferred method of transportation. Nowadays, traveling by bus is a relaxing and entertaining experience. Most bus companies offer different on-board services; ranging from "welcome drinks" to free wi-fi or personal entertainment. For this reason, the bus is often chosen as the best way to get from Mannheim to Prague. Bus companies normally offer comfortable journeys for reasonable prices, and if you choose to travel on a night bus you can even save the money of one night in a hotel. For that reason, the bus is most likely the cheapest way to get to your destination.

Search on Omio to find cheap tickets from Mannheim to Prague. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Mannheim to Prague

Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Prague.

FAQs
There are 3 options to travel between Mannheim and Prague including taking a train, bus, and flight.
The cheapest way to travel from Mannheim to Prague is a bus with an average price of $31 (€25).

This is compared to other travel options from Mannheim to Prague:

A bus is $11 (€9) less than a train for this route with tickets for a train from Mannheim to Prague costing on average $43 (€35).

A bus is $123 (€100) less than a flight for this route with tickets for a flight from Mannheim to Prague costing on average $155 (€125).

The fastest way to travel from Mannheim to Prague is by flight with an average journey time of 1h 0m.

Other travel options to Prague take longer:

Bus takes on average 7h 10m.

Train takes on average 7h 46m.

The distance from Mannheim to Prague is approximately 267 miles (431 km).
The average frequency per day from Mannheim to Prague is:
  • Around 55 flights per day.
  • Around 11 trains per day.
  • Around 7 buses per day.

However, we recommend checking specific travel dates for your route between Mannheim and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mannheim to Prague:
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
  • Trains mostly depart from Mannheim Hbf and arrive in Prague hlavní nádraží.
  • Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Praha, ÚAN Florenc.
If finding a good deal is your main consideration for your trip from Mannheim to Prague, then we'll help you find the best value travel companies for you:
  • Travel with Lufthansa, LOT Polish Airlines to go to Prague by flight.
  • Travel with FlixBus, BlaBlaCar to go to Prague by bus.
  • Travel with Alex, Deutsche Bahn, České dráhy, ÖBB to go to Prague by train.
Yes, there are direct services available from Mannheim to Prague with the following travel companies:
  • 6 direct buses per day with FlixBus, BlaBlaCar.
  • 0 direct trains per day with ÖBB.
Omio customers who travel from Mannheim to Prague often also extend their vacation to go to Vienna, Budapest, Berlin, Dresden, Munich. Omio can help you plan your trip by finding the best connections between Prague and these popular destinations at a great price.
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