Travel Information
Compare train, bus, and flight for Mannheim to Prague
Omio recommends booking the train as it is the most popular option from Mannheim to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a flight, which has an average total journey time of 4h 2m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a flight costs an average of $192.
Distance: 267 miles (431 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$86 Average price | $49 Average price Cheapest | $192 Average price | $114 Average price (fuel + tolls) |
9h 43m Average total duration 9h 13m Onboard + 30m Additional time* | 6h 53m Average total duration 6h 23m Onboard + 30m Additional time* | 4h 2m Average total duration Fastest 2h 2m Onboard + 2h 0m Additional time* | 5h 40m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mannheim to Prague:
A bus is $37 (€30) less than a train for this route with tickets for a train from Mannheim to Prague costing on average $86 (€70).
A bus is $143 (€116) less than a flight for this route with tickets for a flight from Mannheim to Prague costing on average $192 (€155).
Other travel options to Prague take longer:
Bus takes on average 6h 53m.
Train takes on average 9h 43m.
Tickets start at around $86 (€70) compared to roughly $114 (€93) in fuel and tolls — a saving of about $28 (€23). The journey takes 9h 13m versus 5h 40m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Mannheim to Prague
How to get from Mannheim to Prague by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus3:25 AM6h40Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:05 AMPraha, Na Knížecí$471One-way0 transfers
Cheapest
FlixBus3:25 AM6h40Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:05 AMPraha, Na Knížecí$471One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport$1781One-way0 transfers
Other options
ICE 774 · ICE 527 · 3565+
3578:03 AM8h18Mannheim Hbf4:21 PMPrague hlavní nádraží$1491One-way3 transfers
ICE 772 · ICE 621 · 3569+
35910:03 AM8h18Mannheim Hbf6:21 PMPrague hlavní nádraží$1661One-way3 transfers
ICE 513+
3599:33 AM8h48Mannheim Hbf6:21 PMPrague hlavní nádraží$1791One-way1 transfer
FlixBus3:25 AM7h10Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:35 AMPraha, ÚAN Florenc$471One-way0 transfers
FlixBus3:35 PM7h20Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:55 PMPraha, Na Knížecí$471One-way0 transfers
FlixBus5:20 AM7h25Mannheim, ZOB (Heinrich-Von-Stephan-Straße)12:45 PMPraha, Na Knížecí$471One-way0 transfers
ICE 216+
DE44113:55 PM5h30Mannheim Hbf9:25 PMPrague Vaclav Havel Airport$2031One-way1 transfer
ICE 106+
DE44113:33 PM5h52Mannheim Hbf9:25 PMPrague Vaclav Havel Airport$2071One-way1 transfer
ICE 516+
DE44114:34 PM4h51Mannheim Hbf9:25 PMPrague Vaclav Havel Airport$2101One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Mannheim to Prague
The Best Way According to our Users
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FAQs: Travel from Mannheim to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Prague.

This is compared to other travel options from Mannheim to Prague:
A bus is $37 (€30) less than a train for this route with tickets for a train from Mannheim to Prague costing on average $86 (€70).
A bus is $143 (€116) less than a flight for this route with tickets for a flight from Mannheim to Prague costing on average $192 (€155).
Other travel options to Prague take longer:
Bus takes on average 6h 53m.
Train takes on average 9h 43m.
- Around 62 flights per day.
- Around 12 trains per day.
- Around 8 buses per day.
However, we recommend checking specific travel dates for your route between Mannheim and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy, ÖBB, Deutsche Bahn Intercity (DB IC) to go to Prague by train.
- Travel with Lufthansa, Lot Polish Airlines to go to Prague by flight.
- 6 direct buses per day with FlixBus, BlaBlaCar.
- 0 direct trains per day with ÖBB.
- 8 direct flights per day with Lufthansa.
Travelling from Mannheim to Prague: related information
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