4.9
4.6
Travel Information
Compare train, bus, and flight for Mainz to Lyon
Omio recommends booking the flight as it is the most popular option from Mainz to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a flight which can get you there in 1h 18m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.5 - 1.3kg. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $167.
Distance: 333 miles (536 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$327 Average price | $65 Average price Cheapest | $183 Average price (fuel + tolls) |
4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* | 10h 40m Average total duration 10h 10m Onboard + 30m Additional time* | 6h 50m Average total duration (door-to-door) |
1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions Lowest | - CO2 emissions |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mainz to Lyon:
A bus is $262 (€211) less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average $327 (€264).
Other travel options to Lyon take longer:
Train takes on average 6h 2m.
Bus takes on average 10h 10m.
Travel optionsfrom Mainz to Lyon
How to get from Mainz to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Lyon is by taking a train because it’s the best combination of price and speed.
S6 · 13656 · 4557 · ICE 2777:00 AM10h59Mainz Römisches Theater station5:59 PMLyon Part Dieu$1941One-way5 transfers
Cheapest
- S6 · 13656 · 4557 · ICE 2777:00 AM10h59Mainz Römisches Theater station5:59 PMLyon Part Dieu$1941One-way5 transfers
Fastest
- S6 · 13656 · 4557 · ICE 2777:00 AM10h59Mainz Römisches Theater station5:59 PMLyon Part Dieu$1941One-way5 transfers
Other options
- S6 · 4751 · S5 · ICE 2776:33 AM11h26Mainz Römisches Theater station5:59 PMLyon Part Dieu$1941One-way5 transfers
- S5 · ICE 277+
12177+
874246:27 AM11h32Mainz Römisches Theater station5:59 PMLyon Part Dieu$1941One-way3 transfers - 4251 · ICE 511 · ICE 277+121776:14 AM11h45Mainz Römisches Theater station5:59 PMLyon Part Dieu$2021One-way4 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Mainz to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Lyon.
This is compared to other travel options from Mainz to Lyon:
A bus is $262 (€211) less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average $327 (€264).
Other travel options to Lyon take longer:
Train takes on average 6h 2m.
Bus takes on average 10h 10m.
- Around 21 flights per day.
- Around 4 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Mainz and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Lyon, Perrache Bus Station.
- Travel with TGV, SNCF | TGV INOUI, vlexx to go to Lyon by train.
- Travel with Lufthansa to go to Lyon by flight.
- Travel with FlixBus, ORN Omnibusverkehr Rhein-Nahe GmbH to go to Lyon by bus.
- 1 direct trains per day with SNCF | TGV INOUI.
- 4 direct flights per day with Lufthansa.
Travelling from Mainz to Lyon: related information
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