4.9
4.6
Travel Information
Compare train, bus, and flight for Mainz to Lyon
Omio recommends booking the flight as it is the most popular option from Mainz to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $40. For those with little time consider booking a flight which can get you there in 1h 18m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.5 - 1.3kg. The ticket price range depends on the travel mode: a bus costs an average of $40, and a flight costs an average of $164.
Distance: 333 miles (536 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$321 Average price | $64 Average price Cheapest | $180 Average price (fuel + tolls) |
4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* | 10h 40m Average total duration 10h 10m Onboard + 30m Additional time* | 6h 50m Average total duration (door-to-door) |
1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions Lowest | - CO2 emissions |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mainz to Lyon:
A bus is $257 (€211) less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average $321 (€264).
Other travel options to Lyon take longer:
Train takes on average 6h 2m.
Bus takes on average 10h 10m.
Travel optionsfrom Mainz to Lyon
How to get from Mainz to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Lyon is by taking a bus because it’s the best combination of price and speed.
- FlixBus · FlixBus · FlixBus10:30 PM14h20Mainz, Binger Schlag (Kurzzeitparkplatz)12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$701One-way2 transfers
Cheapest
- FlixBus · FlixBus · FlixBus10:30 PM14h20Mainz, Binger Schlag (Kurzzeitparkplatz)12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$701One-way2 transfers
Fastest
- LH107612:20 PM1h20Frankfurt am Main Airport1:40 PMLyon Saint Exupery Airport$4641One-way0 transfers
Other options
S6 · ICE 9590+
121778:57 AM9h02Mainz Römisches Theater station5:59 PMLyon Part Dieu$1811One-way2 transfers- S6 · ICE 9590+55378:57 AM9h02Mainz Römisches Theater station5:59 PMLyon Part Dieu$1811One-way2 transfers
- S5 · ICE 9590+121778:26 AM9h33Mainz Römisches Theater station5:59 PMLyon Part Dieu$1811One-way2 transfers
- FlixBus · FlixBus10:40 PM16h05Mainz, Binger Schlag (Kurzzeitparkplatz)2:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$741One-way1 transfer
- FlixBus · FlixBus · FlixBus10:30 AM18h05Mainz, Binger Schlag (Kurzzeitparkplatz)4:35 AMLyon$871One-way2 transfers
- FlixBus · FlixBus · FlixBus10:30 AM18h20Mainz, Binger Schlag (Kurzzeitparkplatz)4:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$871One-way2 transfers
AF1219 · AF73703:10 PM6h50Frankfurt am Main Airport10:00 PMLyon Saint Exupery Airport$2771One-way1 transfer- AF1519 · AF73689:45 AM8h05Frankfurt am Main Airport5:50 PMLyon Saint Exupery Airport$2771One-way1 transfer
- ICE 23+AF1219 · AF73707:40 AM14h20Mainz Hbf10:00 PMLyon Saint Exupery Airport$2851One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mainz to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Lyon.
This is compared to other travel options from Mainz to Lyon:
A bus is $257 (€211) less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average $321 (€264).
Other travel options to Lyon take longer:
Train takes on average 6h 2m.
Bus takes on average 10h 10m.
- Around 21 flights per day.
- Around 4 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Mainz and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Lyon Part Dieu.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Lyon, Perrache Bus Station.
- Travel with Lufthansa to go to Lyon by flight.
- Travel with FlixBus, ORN Omnibusverkehr Rhein-Nahe GmbH to go to Lyon by bus.
- Travel with TGV, SNCF | TGV INOUI, vlexx to go to Lyon by train.
- 4 direct flights per day with Lufthansa.
- 1 direct trains per day with SNCF | TGV INOUI.
Travelling from Mainz to Lyon: related information
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