How to travel from Mainz to Lyon

Fri, Oct 23
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Travel Information

Compare train, bus, and flight for Mainz to Lyon

Omio recommends booking the train as it is the most popular option from Mainz to Lyon among Omio's users. If you are prioritising price, take the train, with an average ticket price of €22 For those with little time, consider booking a flight, which has an average total journey time of 4h 41m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a train costs an average of €22, while a flight costs an average of €436.

Distance: 333 miles (536 km)

Compare train with

Most popular
Train
Flight
Bus
Driving

€22

Average price

Cheapest

€436

Average price

€61

Average price

€149

Average price

(fuel + tolls)

7h 5m

Average total duration

6h 35m

Onboard

+

30m

Additional time*

4h 41m

Average total duration

Fastest

2h 41m

Onboard

+

2h 0m

Additional time*

13h 55m

Average total duration

13h 25m

Onboard

+

30m

Additional time*

6h 50m

Average total duration

(door-to-door)

0.2 - 0.5kg

CO2 emissions

Lowest

1.6 - 3.2kg

CO2 emissions

0.5 - 1.3kg

CO2 emissions

-

CO2 emissions

SNCF | TGV INOUI

Most popular train company

KLM

Most popular airline

FlixBus

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Compare ways to travel from Mainz to Lyon

Compare the available ways to get from Mainz to Lyon, with the key details around price, speed, convenience, and direct service.

The cheapest way to travel from Mainz to Lyon is a train with an average price of €22.

This is compared to other travel options from Mainz to Lyon:

A train is €40 less than a bus for this route with tickets for a bus from Mainz to Lyon costing on average €61.

A train is €414 less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average €436.

The fastest way to travel from Mainz to Lyon is by flight with an average journey time of 4h 41m.

Other travel options to Lyon take longer:

Train takes on average 7h 5m.

Bus takes on average 13h 55m.

It's helpful to compare your options as there are 3 ways to travel between Mainz and Lyon including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Mainz to Lyon among Omio's users.
Take the train. On this route, it beats driving on both time and money.

The journey is about 15m faster (6h 35m by train vs 6h 50m by car) and roughly €127 cheaper once you factor in fuel and tolls (€22 vs €149). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.

Driving is still worth considering if you want to stop along the way or need a car once you arrive.

Travel options
from Mainz to Lyon

How to get from Mainz to Lyon by train, bus or flight.

Our recommendation

bus

The best way to travel from Mainz to Lyon is by taking a bus because it’s the best combination of price and speed.

  • FlixBusFlixBus · FlixBus
    4:20 PM20h20
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    €701One-way
    1 transfer

Cheapest

  • FlixBusFlixBus · FlixBus
    4:20 PM20h20
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    €701One-way
    1 transfer

Fastest

  • Lufthansa City AirlinesLH4105+LufthansaLH2248
    8:30 AM3h50
    Cologne Bonn Airport
    12:20 PMLyon Saint Exupery Airport
    €6761One-way
    1 transfer

Other options

  • Deutsche BahnS6 · ICE 9590+SNCF | TGV INOUI5537
    8:57 AM9h02
    Mainz Römisches Theater station
    5:59 PMLyon Part Dieu
    €1731One-way
    2 transfers
  • Deutsche BahnS6 · ICE 9590+SNCF | TGV INOUI12177
    8:57 AM9h02
    Mainz Römisches Theater station
    5:59 PMLyon Part Dieu
    €1731One-way
    2 transfers
  • Deutsche BahnS5 · ICE 9590+SNCF | TGV INOUI12177
    8:26 AM9h33
    Mainz Römisches Theater station
    5:59 PMLyon Part Dieu
    €1731One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    10:30 AM17h50
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    4:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    €911One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    10:40 PM14h15
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    €1031One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    8:20 AM14h55
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    €1201One-way
    2 transfers
  • Deutsche BahnICE 23+LufthansaLH1078
    7:40 AM10h30
    Mainz Hbf
    6:10 PMLyon Saint Exupery Airport
    €3161One-way
    1 transfer
  • Deutsche BahnICE 23+KLMKL1818 · KL1435
    7:40 AM15h10
    Mainz Hbf
    10:50 PMLyon Saint Exupery Airport
    €3941One-way
    2 transfers
  • Turkish AirlinesTK1676 · TK1807
    7:15 PM14h00
    Cologne Bonn Airport
    9:15 AMLyon Saint Exupery Airport
    €4101One-way
    1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Mainz to Lyon

Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Lyon.

FAQs
There are 3 options to travel between Mainz and Lyon including taking a train, bus, and flight.
The cheapest way to travel from Mainz to Lyon is a train with an average price of €22.

This is compared to other travel options from Mainz to Lyon:

A train is €40 less than a bus for this route with tickets for a bus from Mainz to Lyon costing on average €61.

A train is €414 less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average €436.

The fastest way to travel from Mainz to Lyon is by flight with an average journey time of 4h 41m.

Other travel options to Lyon take longer:

Train takes on average 7h 5m.

Bus takes on average 13h 55m.

The distance from Mainz to Lyon is approximately 333 miles (536 km).
The average frequency per day from Mainz to Lyon is:
  • Around 30 flights per day.
  • Around 15 trains per day.
  • Around 4 buses per day.

However, we recommend checking specific travel dates for your route between Mainz and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mainz to Lyon:
  • Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
  • Trains mostly depart from Mainz Römisches Theater station and arrive in Lyon Part Dieu.
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
If finding a good deal is your main consideration for your trip from Mainz to Lyon, then we'll help you find the best value travel companies for you:
  • Travel with Lufthansa, BA Euroflyer, Lufthansa Cityline, KLM Cityhopper, CitizenPlane, Brussels Airlines, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Austrian Airlines, Air Baltic, Turkish Airlines, Helvetic Airways, Lot Polish Airlines, British Airways to go to Lyon by flight.
  • Travel with FlixBus to go to Lyon by bus.
  • Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Lyon by train.
Yes, there is a direct route available from Mainz to Lyon:
  • 4 direct flights per day with Lufthansa, Air Dolomiti.
Omio customers who travel from Mainz to Lyon often also extend their vacation to go to Paris, Barcelona, Milan, Geneva, London. Omio can help you plan your trip by finding the best connections between Lyon and these popular destinations at a great price.
Most travelers need at least three days in Lyon to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Lyon, you can explore Les Halles de Lyon Paul Bocuse, an indoor market offering gourmet food, take a river cruise on the Rhône and Saône, and discover the secret passageways of the traboules in Vieux Lyon. Attend a performance at the Opéra de Lyon or visit the Institut Lumière for cinema history. Don't miss the Basilica of Notre-Dame de Fourvière for panoramic views, Vieux Lyon for its Renaissance architecture, Parc de la Tête d'Or with its zoo and botanical garden, the Musée des Confluences, or the bustling Place Bellecour.
For a fulfilling experience in Lyon, spending 2 to 3 days is ideal. This allows you to explore key attractions such as Vieux Lyon, Basilica of Notre-Dame de Fourvière, and the Musée des Confluences, while also enjoying the city's renowned gastronomy and vibrant cultural scene.

Travelling from Mainz to Lyon: related information

Here are some other resources that might have the information you need

HomeTravelTravel to FranceTravel to LyonHow to travel from Mainz to Lyon

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