- Must visit
Musée des Beaux-Arts de Lyon
One of France's finest art museums outside Paris, with major collections from antiquity to modern art in a former abbey.
Omio recommends booking the train as it is the most popular option from Mainz Hbf to Lyon Part Dieu among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a train which can get you there in 5h 59m. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $329.
Distance: 332 miles (535 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$236 Average price | $52 Average price Cheapest | $329 Average price | $130 Average price (fuel + tolls) |
6h 29m Average total duration Fastest 5h 59m Onboard + 30m Additional time* | 13h 55m Average total duration 13h 25m Onboard + 30m Additional time* | 18h 20m Average total duration 15h 20m Onboard + 3h 0m Additional time* | 6h 8m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mainz Hbf to Lyon Part Dieu:
A bus is $184 (€151) less than a train for this route with tickets for a train from Mainz Hbf to Lyon Part Dieu costing on average $236 (€193).
A bus is $277 (€227) less than a flight for this route with tickets for a flight from Mainz Hbf to Lyon Part Dieu costing on average $329 (€270).
Other travel options to Lyon Part Dieu take longer:
Bus takes on average 13h 25m.
Flight takes on average 15h 20m.
You'll arrive about 9m sooner (5h 59m by train vs 6h 8m by car). Tickets start at around $236 (€193) compared to roughly $130 (€107) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Mainz Hbf to Lyon Part Dieu run on average 1 times per day, taking around 5h 59m. Cheap train tickets for this journey start at $236 (€193) but you can travel from only $52 (€42) by bus.
The earliest train runs at 13:13, the last at 13:13. The fastest train covers the 332 miles (535 km) distance in 6h 45m.
Distance 332 miles (535 km) |
Average train duration 5h 59m |
Cheapest ticket price $236 (€193) |
Trains per day 1 |
Fastest train 6h 45m |
First train 1:13 PM |
Last train 1:13 PM |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Lyon Part Dieu — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon Part Dieu trip today.
One of France's finest art museums outside Paris, with major collections from antiquity to modern art in a former abbey.
Essential museum for understanding Roman Lyon, paired with remarkable ancient theaters on Fourvière hill.
Popular museum showcasing film props, special effects, and detailed miniature scenes in Vieux Lyon.
UNESCO-listed old quarter with Renaissance streets, traboules, lively lanes, and some of the city's most atmospheric walks.
One of Europe's largest pedestrian squares and a major orientation point in central Lyon.
Central district between the Rhône and Saône, ideal for walking between grand squares, shopping streets, and monuments.
Light dumplings traditionally made with pike and served with a rich Nantua crayfish sauce, a classic Lyonnais specialty.
A warm salad of frisée lettuce, lardons, croutons, and a poached egg, emblematic of Lyon's bouchon cuisine.
Pork sausage baked inside a soft brioche loaf, a traditional hearty dish found in many classic Lyon eateries.
Well-known bouchon by chef Joseph Viola, celebrated for traditional Lyonnais specialties in a refined yet convivial atmosphere.
Historic grand brasserie serving Lyonnais and Alsatian classics in a vast Art Deco dining room; a famous institution in Lyon.
Classic Lyon bouchon with a strong local reputation for generous traditional dishes, fixed menus, and a warm old-style dining room.
Moderate for France. Casual dining and coffee are reasonable, while hotels and fine dining near the station can be pricier.
Service is included in restaurant bills. Tipping is not required, but leaving 5-10% for very good service is appreciated. Round up in cafes and taxis.
Official public transport app
Lyon Part-Dieu -> Place Bellecour, Lyon
Find answers to the most common questions about traveling from Mainz Hbf to Lyon Part Dieu by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon Part Dieu, this guide helps you travel smarter and with confidence.

Most Mainz Hbf to Lyon Part Dieu trains use the Frankfurt (Main) Hbf to Lyon Part Dieu station pair. Use this guide to compare Mainz Hbf and Lyon Part Dieu train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Mainz Hbf is 2 km from Mainz city centre. Public transport options include:
Mainz Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Mangal, Asia Wok, Bistrorante Midi, McDonald's
Wi-Fi is available at Mainz Hbf. ATMs are available at Mainz Hbf.
Ticket office support is available at Mainz Hbf. Information desks are available at Mainz Hbf.
Luggage storage is available at Mainz Hbf. Lost and found is available at the station.
Available at Mainz Hbf: Parking, Taxis, WC.
Available at Mainz Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mainz Hbf.
Nearby hotels include Advena Europa Hotel, GuestHouse Mainz, Terminus, Hotel Moguntia.
Mainz-Marienborn is 4 km from Mainz city centre. Public transport options include:
Mainz-Marienborn has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Asia Snack Fu Loi, Artos, Pizzaria Da Raffaele, Hikari Sushi Bar
Wi-Fi is available at Mainz-Marienborn. ATMs are available at Mainz-Marienborn.
Ticket office support is available at Mainz-Marienborn. Information desks are available at Mainz-Marienborn.
Luggage storage is available at Mainz-Marienborn. Lost and found is available at the station.
Available at Mainz-Marienborn: Parking, Taxis, WC.
Available at Mainz-Marienborn: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mainz-Marienborn.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
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