The cheapest and fastest trains from Boston, MA to St. Louis, MO
Cheapest price
$275
Average price
$275
Fastest journey
1 d 12 h 19 m
Average duration
1 d 12 h 19 m
Trains per day
1
Distance
1667 km
The best way to find a cheap train ticket from Boston, MA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to St. Louis, MO will cost around $275 if you buy it on the day, but the cheapest tickets can be found for only $275.
Of the 1 trains that leave Boston, MA for St. Louis, MO on Wed, Nov 26, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 26 the direct trains cover the 1667 km distance in an average of 1 d 12 h 19 m but if you time it right, some trains will get you there in just 1 d 12 h 19 m .
On Wed, Nov 26 the slowest trains will take 1 d 12 h 19 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Boston, MA to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Boston, MA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €67. For those with little time consider booking a flight which can get you there in 3h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of €67, and a flight costs an average of €85.
Distance: 1035 miles (1667 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€182 Average price | €276 Average price | €121 Average price Cheapest |
27h 56m Average total duration 27h 26m Onboard + 30m Additional time* | 6h 50m Average total duration Fastest 3h 50m Onboard + 3h 0m Additional time* | 27h 58m Average total duration 27h 28m Onboard + 30m Additional time* |
0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | 1.7 - 4.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Boston, MA to St. Louis, MO train times
The table below shows live departures for Boston, MA to St. Louis, MO trains for today, Tuesday, November 25. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:50 PM Boston, MA | 36h19 | 5:09 AM St. Louis, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Boston, MA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Why should you book Boston to St. Louis trains with Omio?
Amtrak operates all train services from Boston to St. Louis. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Boston to St. Louis.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Boston to St. Louis.
Journey information
Overview: Train from Boston, MA to St. Louis, MO
Trains from Boston, MA to St. Louis, MO run on average 7 times per day, taking around 27h 26m. Cheap train tickets for this journey start at $138 (€112) but you can travel from only $82 (€67) by bus.
The earliest train runs at 08:10, the last at 14:55. The fastest train covers the 1035 miles (1667 km) distance in 36h 19m.
Distance 1035 miles (1667 km) |
Average train duration 27h 26m |
Cheapest ticket price $138 (€112) |
Trains per day 7 |
Fastest train 36h 19m |
First train 08:10 |
Last train 14:55 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Boston, MA to St. Louis, MO start from as low as $138 (€112) if booked well in advance.
- Standard Fares: Typically, trains cost $223 (€182) depending on the train type and class.
Journey Duration & Frequency
- On average there are 7 daily trains from Boston, MA to St. Louis, MO with 0 direct service.
- The fastest trains can take as little as 36h 19m but the average duration is 27h 26m
Train Operators
- Travel from Boston, MA to St. Louis, MO with Amtrak
- The most booked train company for this route on Omio is Amtrak.
Stations & Schedule
- Most trains depart from South Station, Boston, MA and arrive in St. Louis Station, St. Louis, MO
- First train typically departs at 08:10 AM and the last at 02:55 PM
Train companies: Amtrak from Boston, MA to St. Louis, MO trainsAmtrak trains will get you between Boston, MA and St. Louis, MO from $82 (€67). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Boston, MA to St. Louis, MO
Find answers to the most common questions about traveling from Boston, MA to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Boston, MA to St. Louis, MO
- 5:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via Atlantic Avenue.
- Legal Sea Foods
- Tavern in the Square
- Outside the main entrance.
- Elevators, restrooms.
- $0.50
- InterContinental Boston
- The Langham, Boston
- Boston Harbor Hotel
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for Amtrak services
- Hall 2: platforms 6-13 for MBTA Commuter Rail services
- Bus terminal located on the upper level.
- Subway: Red Line
- Bus: Several lines available
- Commuter Rail: Multiple lines
- 5:00 AM - 1:00 AM Monday - Sunday
- Free
- Parking is available nearby with several garages in the vicinity.
- Sorellina
- Atlantic Fish Company
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $0.50
- Copley Square Hotel
- The Westin Copley Place
- Fairmont Copley Plaza
- Located in the main hall
- Avis
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for Amtrak and MBTA Commuter Rail
- Hall 2: Orange Line subway platforms
- Subway: Orange Line
- Bus: Several lines available
- Commuter Rail: Framingham/Worcester Line, Franklin Line, Needham Line, Providence/Stoughton Line
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from Boston, MA
More options for your journey from Boston, MA to St. Louis, MO
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