- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.

Cheapest price
$317
Average price
$317
Fastest journey
33h 7m
Average duration
33h 7m
Trains per day
1
Distance
422 km
Omio recommends booking the bus as it is the most popular option from Baltimore, MD to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $91. For those with little time consider booking a flight which can get you there in 3h 34m. The ticket price range depends on the travel mode: a bus costs an average of $91, and a train costs an average of $128.
Distance: 730 miles (1176 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$321 Average price | $207 Average price Cheapest | $244 Average price | $174 Average price (fuel + tolls) |
26h 29m Average total duration 25h 59m Onboard + 30m Additional time* | 21h 10m Average total duration 20h 40m Onboard + 30m Additional time* | 6h 34m Average total duration Fastest 3h 34m Onboard + 3h 0m Additional time* | 12h 58m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Baltimore, MD to St. Louis, MO:
A bus is $37 (€30) less than a flight for this route with tickets for a flight from Baltimore, MD to St. Louis, MO costing on average $244 (€201).
A bus is $114 (€94) less than a train for this route with tickets for a train from Baltimore, MD to St. Louis, MO costing on average $321 (€264).
Other travel options to St. Louis, MO take longer:
Bus takes on average 20h 40m.
Train takes on average 25h 59m.
Tickets start at around $321 (€264) compared to roughly $174 (€144) in fuel and tolls — a saving of about $-146.29 (€-120.55). The journey takes 25h 59m versus 12h 58m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Baltimore, MD to St. Louis, MO trains for today, Tuesday, July 14. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
174 Northeast Regional · 49 Lake Shore Limited · 21 Texas Eagle | 11:18 AM Pennsylvania Station, Baltimore, MD | 33h07 | 7:25 PM St. Louis Station, St. Louis, MO | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Baltimore, MD to St. Louis, MO run on average 4 times per day, taking around 25h 59m. Cheap train tickets for this journey start at $128 (€105) but you can travel from only $91 (€75) by bus.
The earliest train runs at 08:10, the last at 14:21. The fastest train covers the 730 miles (1176 km) distance in 29h 34m.
Distance 730 miles (1176 km) |
Average train duration 25h 59m |
Cheapest ticket price $128 (€105) |
Trains per day 4 |
Fastest train 29h 34m |
First train 8:10 AM |
Last train 2:21 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 84 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Baltimore, MD to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Baltimore, MD to St. Louis, MO trains use the Pennsylvania Station to St. Louis Station station pair. Use this guide to compare Baltimore, MD and St. Louis, MO train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pennsylvania Station is 1 km from Baltimore city centre. Public transport options include:
Pennsylvania Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: The Helmand, Tapas Teatro
Free. ATMs are available in the train station.
Ticket office support is available at Pennsylvania Station. Information desks are located in the main hall.
Luggage storage is available at Pennsylvania Station. Lost and found is available at the station.
Available at Pennsylvania Station: Parking, Taxis, WC.
Available at Pennsylvania Station: Bike Parking, Car Rental.
Accessibility facilities are available at Pennsylvania Station: Elevators, ramps.
Nearby hotels include Hotel Indigo Baltimore Downtown, The Ivy Hotel, Hotel Revival Baltimore.
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Landry's Seafood House, The Station Grille
Free. ATMs are available in the train station.
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Available at St. Louis Station: Parking, Taxis, WC.
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Here are some other resources that might have the information you need