The cheapest and fastest trains from Indianapolis, IN to St. Louis, MO
Cheapest price
$116
Average price
$116
Fastest journey
12 h 58 m
Average duration
12 h 58 m
Trains per day
1
Distance
370 km
The best way to find a cheap train ticket from Indianapolis, IN to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to St. Louis, MO will cost around $116 if you buy it on the day, but the cheapest tickets can be found for only $116.
It's difficult to get from Indianapolis, IN to St. Louis, MO without transferring at least once.
8255 AMTRAK · 305 Lincoln Service10:25 AM12h58Indianapolis Station, Indianapolis, IN10:23 PMSt. Louis Station, St. Louis, MO$1161One-way1 transfer
8255 AMTRAK · 305 Lincoln Service10:25 AM12h58Indianapolis Station, Indianapolis, IN10:23 PMSt. Louis Station, St. Louis, MO$1161One-way1 transfer
Travel Information
Compare train, bus, and flight for Indianapolis, IN to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a bus which can get you there in 5h 22m. The ticket price range depends on the travel mode: a bus costs an average of $33, and a flight costs an average of $138.
Distance: 229 miles (370 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$125 Average price | $55 Average price Cheapest | $337 Average price | $50 Average price (fuel + tolls) |
8h 58m Average total duration 8h 28m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 5h 22m Onboard + 30m Additional time* | 11h 43m Average total duration 8h 43m Onboard + 3h 0m Additional time* | 3h 31m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Indianapolis, IN to St. Louis, MO:
A bus is $71 (€57) less than a train for this route with tickets for a train from Indianapolis, IN to St. Louis, MO costing on average $125 (€101).
A bus is $282 (€228) less than a flight for this route with tickets for a flight from Indianapolis, IN to St. Louis, MO costing on average $337 (€272).
Other travel options to St. Louis, MO take longer:
Train takes on average 8h 28m.
Flight takes on average 8h 43m.
Tickets start at around $125 (€101) compared to roughly $50 (€41) in fuel and tolls — a saving of about $-74.98 (€-60.56). The journey takes 8h 28m versus 3h 31m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Indianapolis, IN to St. Louis, MO train times
The table below shows live departures for Indianapolis, IN to St. Louis, MO trains for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
8255 AMTRAK · 305 Lincoln Service | 10:25 AM Indianapolis Station, Indianapolis, IN | 12h58 | 10:23 PM St. Louis Station, St. Louis, MO | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 02
Journey information
Overview: Train from Indianapolis, IN to St. Louis, MO
Trains from Indianapolis, IN to St. Louis, MO run on average 3 times per day, taking around 8h 28m. Cheap train tickets for this journey start at $69 (€55) but you can travel from only $33 (€27) by bus.
The earliest train runs at 04:30, the last at 15:39. The fastest train covers the 229 miles (370 km) distance in 12h 33m.
Distance 229 miles (370 km) |
Average train duration 8h 28m |
Cheapest ticket price $69 (€55) |
Trains per day 3 |
Fastest train 12h 33m |
First train 4:30 AM |
Last train 3:39 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 1 day |
Train companies: Amtrak from Indianapolis, IN to St. Louis, MO trainsAmtrak trains will get you between Indianapolis, IN and St. Louis, MO from $33 (€27). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Indianapolis, IN to St. Louis, MO
Find answers to the most common questions about traveling from Indianapolis, IN to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Indianapolis, IN to St. Louis, MO
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to St. Louis, MO
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