The cheapest and fastest trains from Indianapolis, IN to St. Louis, MO
Cheapest price
$108
Average price
$117
Fastest journey
12 h 33 m
Average duration
13 h 20 m
Trains per day
2
Distance
370 km
The best way to find a cheap train ticket from Indianapolis, IN to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to St. Louis, MO will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $108.
Of the 2 trains that leave Indianapolis, IN for St. Louis, MO on Mon, Jan 12, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jan 12 the direct trains cover the 370 km distance in an average of 13 h 20 m but if you time it right, some trains will get you there in just 12 h 33 m .
On Mon, Jan 12 the slowest trains will take 14 h 7 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Indianapolis, IN to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a bus which can get you there in 5h 28m. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €86.
Distance: 229 miles (370 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€99 Average price | €43 Average price Cheapest | €265 Average price |
8h 58m Average total duration 8h 28m Onboard + 30m Additional time* | 5h 58m Average total duration Fastest 5h 28m Onboard + 30m Additional time* | 11h 43m Average total duration 8h 43m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Indianapolis, IN to St. Louis, MO train times
The table below shows live departures for Indianapolis, IN to St. Louis, MO trains for today, Sunday, January 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:10 AM Indianapolis, IN | 9h30 | 8:40 PM St. Louis, MO | 0 transfersDirect | |
![]() | 2:50 PM Indianapolis, IN | 12h33 | 3:23 AM St. Louis, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 12
Jan 13
Jan 14
Jan 15
Jan 16
Jan 17
Jan 18
Why should you book Indianapolis to St. Louis trains with Omio?
Amtrak operates all train services from Indianapolis to St. Louis. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Indianapolis to St. Louis.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Indianapolis to St. Louis.
Journey information
Overview: Train from Indianapolis, IN to St. Louis, MO
Trains from Indianapolis, IN to St. Louis, MO run on average 4 times per day, taking around 8h 28m. Cheap train tickets for this journey start at $81 (€66) but you can travel from only $34 (€28) by bus.
The earliest train runs at 06:00, the last at 14:55. The fastest train covers the 229 miles (370 km) distance in 9h 30m.
Distance 229 miles (370 km) |
Average train duration 8h 28m |
Cheapest ticket price $81 (€66) |
Trains per day 4 |
Fastest train 9h 30m |
First train 06:00 |
Last train 14:55 |
Train companies: Amtrak from Indianapolis, IN to St. Louis, MO trainsAmtrak trains will get you between Indianapolis, IN and St. Louis, MO from $34 (€28). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Indianapolis, IN to St. Louis, MO
Find answers to the most common questions about traveling from Indianapolis, IN to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Indianapolis, IN to St. Louis, MO
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to St. Louis, MO
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