The cheapest and fastest trains from Syracuse, NY to St. Louis, MO
Cheapest price
$493
Average price
$493
Fastest journey
21 h 2 m
Average duration
21 h 2 m
Trains per day
1
Distance
1278 km
The best way to find a cheap train ticket from Syracuse, NY to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to St. Louis, MO will cost around $493 if you buy it on the day, but the cheapest tickets can be found for only $493.
It's difficult to get from Syracuse, NY to St. Louis, MO without transferring at least once.
10:05 PM21h02Syracuse, NY7:07 PMSt. Louis, MO$4931One-way1 transfer
10:05 PM21h02Syracuse, NY7:07 PMSt. Louis, MO$4931One-way1 transfer
Travel Information
Compare train, bus, and flight for Syracuse, NY to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Syracuse, NY to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from $155. For those with little time consider booking a flight which can get you there in 6h 10m. The ticket price range depends on the travel mode: a train costs an average of $155, and a flight costs an average of $374.
Distance: 794 miles (1278 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$213 Average price Cheapest | $289 Average price | $383 Average price |
18h 48m Average total duration 18h 18m Onboard + 30m Additional time* | 27h 45m Average total duration 27h 15m Onboard + 30m Additional time* | 9h 10m Average total duration Fastest 6h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Syracuse, NY to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 06
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May 12
Journey information
Overview: Train from Syracuse, NY to St. Louis, MO
Trains from Syracuse, NY to St. Louis, MO run on average 4 times per day, taking around 18h 18m. Cheap train tickets for this journey start at $155 (€124) if you book in advance.
The earliest train runs at 06:35, the last at 22:05. The fastest train covers the 794 miles (1278 km) distance in 22h 20m.
Distance 794 miles (1278 km) |
Average train duration 18h 18m |
Cheapest ticket price $155 (€124) |
Trains per day 4 |
Fastest train 22h 20m |
First train 6:35 AM |
Last train 10:05 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Train companies: Amtrak from Syracuse, NY to St. Louis, MO trainsAmtrak trains will get you between Syracuse, NY and St. Louis, MO from $155 (€124). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Syracuse, NY to St. Louis, MO
Find answers to the most common questions about traveling from Syracuse, NY to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Syracuse, NY to St. Louis, MO
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available at the station.
- Dinosaur Bar-B-Que
- The Mission Restaurant
- Outside the main entrance.
- $1
- Embassy Suites by Hilton Syracuse
- Comfort Inn & Suites Airport
- Best Western Syracuse Downtown Hotel and Suites
- Located in the main hall
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and bus services
- Bus: Centro Bus Service
- Taxi: Available outside the station
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
More options for your journey from Syracuse, NY to St. Louis, MO
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