The cheapest and fastest trains from Syracuse, NY to St. Louis, MO
Cheapest price
$363
Average price
$363
Fastest journey
21 h 2 m
Average duration
21 h 2 m
Trains per day
1
Distance
1278 km
The best way to find a cheap train ticket from Syracuse, NY to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to St. Louis, MO will cost around $363 if you buy it on the day, but the cheapest tickets can be found for only $363.
It's difficult to get from Syracuse, NY to St. Louis, MO without transferring at least once.


Travel Information
Compare train, bus, and flight for Syracuse, NY to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Syracuse, NY to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from €289. For those with little time consider booking a train which can get you there in 18h 23m. The ticket price range depends on the travel mode: a train costs an average of €289, and a bus costs an average of €312.
Distance: 794 miles (1278 km)
Compare train with
Most popular Train | Bus |
|---|---|
€289 Average price Cheapest | €352 Average price |
18h 53m Average total duration Fastest 18h 23m Onboard + 30m Additional time* | 29h 17m Average total duration 28h 47m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Syracuse, NY to St. Louis, MO train times
The table below shows live departures for Syracuse, NY to St. Louis, MO trains for today, Wednesday, February 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:05 PM Syracuse, NY | 21h02 | 7:07 PM St. Louis, MO | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Syracuse, NY to St. Louis, MO
Trains from Syracuse, NY to St. Louis, MO run on average 4 times per day, taking around 18h 23m. Cheap train tickets for this journey start at $364 (€289) if you book in advance.
The earliest train runs at 06:35, the last at 22:05. The fastest train covers the 794 miles (1278 km) distance in 21h 2m.
Distance 794 miles (1278 km) |
Average train duration 18h 23m |
Cheapest ticket price $364 (€289) |
Trains per day 4 |
Fastest train 21h 2m |
First train 06:35 |
Last train 22:05 |
Train companies: Amtrak from Syracuse, NY to St. Louis, MO trainsAmtrak trains will get you between Syracuse, NY and St. Louis, MO from $364 (€289). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Syracuse, NY to St. Louis, MO
Find answers to the most common questions about traveling from Syracuse, NY to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Syracuse, NY to St. Louis, MO
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available at the station.
- Dinosaur Bar-B-Que
- The Mission Restaurant
- Outside the main entrance.
- $1
- Embassy Suites by Hilton Syracuse
- Comfort Inn & Suites Airport
- Best Western Syracuse Downtown Hotel and Suites
- Located in the main hall
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and bus services
- Bus: Centro Bus Service
- Taxi: Available outside the station
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
More options for your journey from Syracuse, NY to St. Louis, MO
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