- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 20
€882
Average ticket price on Sep 20
€882
Fastest journey on Sep 20
22 h 20 m
Average journey duration on Sep 20
22 h 20 m
Trains on Sep 20
1
Distance
1278 km
The best way to find a cheap train ticket from Syracuse, NY to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to St. Louis, MO will cost around €882 if you buy it on the day, but the cheapest tickets can be found for only €882.
On Sun, Sep 20, we found 1 trains from Syracuse, NY to St. Louis, MO, including 1 direct services.
On Sun, Sep 20 the direct trains cover the 1278 km distance in an average of 22 h 20 m but if you time it right, some trains will get you there in just 22 h 20 m .
On Sun, Sep 20 the slowest trains will take 22 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Syracuse, NY to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €131 For those with little time, consider booking a flight, which has an average total journey time of 6h 28m. Average ticket prices depend on the travel mode: a bus costs an average of €131, while a train costs an average of €611.
Distance: 794 miles (1278 km)
Most popular Train | Flight | Bus |
|---|---|---|
€611 Average price | €546 Average price | €131 Average price Cheapest |
19h 5m Average total duration 18h 35m Onboard + 30m Additional time* | 6h 28m Average total duration Fastest 4h 28m Onboard + 2h 0m Additional time* | 19h 39m Average total duration 19h 9m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse, NY to St. Louis, MO:
A bus is €415 less than a flight for this route with tickets for a flight from Syracuse, NY to St. Louis, MO costing on average €546.
A bus is €480 less than a train for this route with tickets for a train from Syracuse, NY to St. Louis, MO costing on average €611.
Other travel options to St. Louis, MO take longer:
Train takes on average 18h 35m.
Bus takes on average 19h 9m.
The table below shows live departures for Syracuse, NY to St. Louis, MO trains for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:05 AM Syracuse, NY | 22h20 | 12:25 AM St. Louis, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Syracuse, NY to St. Louis, MO run on average 3 times per day, taking around 18h 28m. Cheap train tickets for this journey start at €183 but you can travel from only €86 by bus.
The earliest train runs at 06:35, the last at 22:05. The fastest train covers the 794 miles (1278 km) distance in 18h 6m.
Distance 794 miles (1278 km) |
Average train duration 18h 28m |
Cheapest ticket price €183 |
Trains per day 3 |
Fastest train 18h 6m |
First train 6:35 AM |
Last train 10:05 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Syracuse, NY to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to St. Louis, MO trains use the Syracuse Station to St. Louis Station station pair. Use this guide to compare Syracuse, NY and St. Louis, MO train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Syracuse Station is 3 km from Syracuse city centre. Public transport options include:
Syracuse Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Car Rental, Information Desk, and Luggage Carts.
Food options include: Dinosaur Bar-B-Que, The Mission Restaurant
Ticket office support is available at Syracuse Station. Information desks are located in the main hall.
Luggage storage is available at Syracuse Station. Lost and found is available at the station.
Available at Syracuse Station: Parking, Taxis, WC.
Available at Syracuse Station: Car Rental.
Accessibility facilities are available at Syracuse Station.
Nearby hotels include Embassy Suites by Hilton Syracuse, Comfort Inn & Suites Airport, Best Western Syracuse Downtown Hotel and Suites.
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Landry's Seafood House, The Station Grille
Free. ATMs are available in the train station.
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Available at St. Louis Station: Parking, Taxis, WC.
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Here are some other resources that might have the information you need