- Must visit
National Museum of Civil War Medicine
Interactive museum explaining battlefield medicine, surgery, and care during the Civil War in a historic downtown building.
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Journey information
Overview: Bus from Winston Salem, NC to Frederick, MD
USAUSA
Buses from Winston Salem, NC to Frederick, MD run on average 2 times per day, taking around 10h 48m. Cheap bus tickets for this journey start at €59 if you book in advance.
The earliest bus runs at 11:10, the last at 21:55. The fastest bus covers the 276 miles (445 km) distance in 10h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance276 miles (445 km)
- Average bus duration10h 48m
- Cheapest ticket price€59
- Buses per day2
- Fastest bus10h 45m
- First bus11:10 AM
- Last bus9:55 PM
- Cheapest MonthSep
- Cheapest DaySat
- High SeasonJul - Sep
- Low SeasonJul - Sep
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Winston Salem, NC to Frederick, MD trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Winston Salem, NC to Frederick, MD.
Cheap bus tickets from Winston Salem, NC to Frederick, MD can start from as little as €59 when you book in advance. The average bus ticket price for Winston Salem, NC to Frederick, MD is €77 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Winston Salem, NC to Frederick, MD leaves at 11:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Winston Salem, NC to Frederick, MD leaves at 9:55 PM.
There are 2 buses a day from Winston Salem, NC to Frederick, MD which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
Why should you book Winston Salem, NC to Frederick, MD buses with Omio?
Greyhound as well as FlixBus offer buses services from Winston Salem, NC to Frederick, MD.
Omio is an official ticket reseller for all your travel options from Winston Salem, NC to Frederick, MD.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Winston Salem, NC to Frederick, MD.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Winston Salem, NC to Frederick, MD.
Bus companies
Bus companies from Winston Salem, NC to Frederick, MD
Buses from Winston Salem, NC to Frederick, MD with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 45m
Cheapest FlixBus Price
€71
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 50m
Cheapest Greyhound Price
€59
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Winston Salem, NC and Frederick, MD
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Winston Salem, NC to Frederick, MD, you can count on Greyhound, FlixBus for the best way to get you to Frederick, MD. You can also check all possible bus companies who offer a service between Winston Salem, NC and Frederick, MD and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Winston Salem, NC to Frederick, MD:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Winston Salem, NC to Frederick, MD for bus company Greyhound, FlixBus.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Whether you can cancel your bus ticket from Winston Salem, NC to Frederick, MD depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, there is food available to purchase on board the bus from Winston Salem, NC to Frederick, MD.
Yes, the following luggage options are included when booking a bus ticket from Winston Salem, NC to Frederick, MD:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Winston Salem, NC to Frederick, MD:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Winston Salem, NC to Frederick, MD. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Winston Salem, NC to Frederick, MD with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Winston Salem, NC to Frederick, MD with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Winston Salem, NC to Frederick, MD with the following bus company: Greyhound, FlixBus.
Complete guide to Frederick, MD
Things to do in Frederick, MD
Discover the best of Frederick, MD — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frederick, MD trip today.
- Recommended
Heritage Frederick
Regional history museum with exhibits on Frederick County life, culture, and changing communities inside a restored historic home.
- Recommended
Delaplaine Arts Center
Contemporary art space in downtown Frederick presenting rotating exhibitions by regional and national artists in a modern gallery setting.
- Must visit
Carroll Creek Linear Park
Linear downtown park and promenade with fountains, public art, bridges, and event spaces, ideal for walking day or evening.
- Must visit
Downtown Frederick Historic District
Central historic district with preserved architecture, local shops, galleries, and easy access to many of Frederick’s main sights.
- Recommended
North Market Street
Popular downtown street lined with historic buildings, boutiques, public art, and one of the city’s best pedestrian atmospheres.
Maryland Crab Cakes
Maryland crab cakes are packed with blue crab and light seasoning. They are a regional staple near Frederick and widely served across Central Maryland.
Cream Of Crab Soup
Cream of crab soup is a rich Maryland favorite made with crab meat, cream, and seasoning. It reflects the state's strong Chesapeake seafood tradition.
- Vegetarian
Smith Island Cake
Smith Island cake is Maryland's official state dessert, with many thin cake layers and frosting. It is a classic sweet treat found around Frederick.
Milkhouse Brewery
Well-known farm brewery outside downtown with estate beer, pizza, and scenic grounds suited to relaxed afternoons.
The Tasting Room
Contemporary American restaurant known for wood-fired dishes, cocktails, and a polished but relaxed downtown atmosphere.
Pistarro's
Casual local favorite for New York-style pizza, pasta, and Italian-American comfort food in the historic district.
United States Dollar ($)
Moderate for a U.S. mid-size city: hotels and dining are below major metros, but car-based transport and limited transit can raise visitor costs.
Average meal costs
- Budget
- $10-15 for fast food or casual takeaway.
- Mid-range
- $18-35 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars; $1-2 is common.
Plan your visit to Frederick, MD
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Frederick, MD.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Frederick, MD, travelers should be cautious of common urban safety concerns such as petty theft and pickpocketing, especially in crowded areas and during events. It is advisable to stay aware of surroundings and avoid poorly lit or isolated locations at night. Scams targeting travelers are relatively rare but may include overpriced taxi services or unofficial tour offers; using licensed transportation and booking tours through reputable providers helps prevent these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Winston Salem, NC to Frederick, MD
Find answers to the most common questions about traveling from Winston Salem, NC to Frederick, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frederick, MD, this guide helps you travel smarter and with confidence.
Yes, you can take a between Winston Salem, NC and Frederick, MD.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Winston Salem, NC to Frederick, MD
Most Winston Salem, NC to Frederick, MD buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Frederick, East Street (Transit Center) station pair. Use this guide to compare Winston Salem, NC and Frederick, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Winston Salem
Arrival bus stations in Frederick
Which Winston Salem, NC station do buses to Frederick, MD leave from?
Buses from Winston Salem, NC to Frederick, MD leave from Winston Salem, W 5th St (Greyhound Bus Station). The station is from Winston Salem, NC city centre at W 5th St, Winston-Salem, NC 27101, USA.
Winston Salem, W 5th St (Greyhound Bus Station)W 5th St, Winston-Salem, NC 27101, USA
City-centre transport
Getting to Winston Salem, W 5th St (Greyhound Bus Station) from Winston Salem city centre
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Winston Salem, W 5th St (Greyhound Bus Station) bus station facilities and services
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Which Frederick, MD station do buses from Winston Salem, NC arrive at?
Buses from Winston Salem, NC to Frederick, MD arrive at Frederick, East Street (Transit Center). Frederick, East Street (Transit Center) is 0 miles (1 km) from Frederick, MD city centre.
Frederick, East Street (Transit Center)Frederick, MD, USA
City-centre transport
Getting to Frederick, East Street (Transit Center) from Frederick city centre
TrainSouthwest Chief · 63h 13m · €794
Southwest Chief · 67h 1m · €970
BusGreyhound US1210 · 63h 11m · €527
Frederick, East Street (Transit Center) bus station facilities and services
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Tickets and information
Ticket office support is available at Frederick, East Street (Transit Center).
Parking, taxis and toilets
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Bus stations for Winston Salem, NC to Frederick, MD
Check bus stations information for Winston Salem, NC and Frederick, MD, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Winston Salem, W 5th St (Greyhound Bus Station), which is located around away from the city centre, and they get off the bus at Frederick, East Street (Transit Center), located 1 away from the city centre.
Most popular bus connections from Winston Salem, NC
Most popular buses to and from Frederick, MD and Winston Salem, NC
Most popular bus connections to Frederick, MD
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