4.9
4.6The cheapest and fastest buses from Winston Salem, NC to Frederick, MD
Cheapest price on Sep 19
$73
Average ticket price on Sep 19
$81
Fastest journey on Sep 19
12 h 15 m
Average journey duration on Sep 19
13 h 25 m
Buses on Sep 19
2
Distance
445 km
The best way to find a cheap bus ticket from Winston Salem, NC to Frederick, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Frederick, MD will cost around $81 if you buy it on the day, but the cheapest tickets can be found for only $73.
It's difficult to get from Winston Salem, NC to Frederick, MD without transferring at least once.
· 7:10 AM12h15Winston Salem, W 5th St (Greyhound Bus Station), NC7:25 PMFrederick, East Street (Transit Center)$731One-way1 transfer
FlixBus+ · · 5:55 PM14h35Winston Salem, W 5th St (Greyhound Bus Station), NC8:30 AMFrederick, East Street (Transit Center)$881One-way3 transfers
- · 7:10 AM12h15Winston Salem, W 5th St (Greyhound Bus Station), NC7:25 PMFrederick, East Street (Transit Center)$731One-way1 transfer
- FlixBus+ · · 5:55 PM14h35Winston Salem, W 5th St (Greyhound Bus Station), NC8:30 AMFrederick, East Street (Transit Center)$881One-way3 transfers
Travel Information
Compare bus for Winston Salem, NC to Frederick, MD
Omio recommends booking the flight as it is the most popular option from Winston Salem, NC to Frederick, MD among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $107 For those with little time, consider booking a flight, which has an average total journey time of 5h 39m. Average ticket prices depend on the travel mode: a bus costs an average of $107, while a flight costs an average of $609.
Distance: 276 miles (445 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$107 Average price Cheapest | $609 Average price | $67 Average price (fuel + tolls) |
11h 18m Average total duration 10h 48m Onboard + 30m Additional time* | 5h 39m Average total duration Fastest 3h 39m Onboard + 2h 0m Additional time* | 5h 38m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Winston Salem, NC to Frederick, MD:
A bus is $502 (€411) less than a flight for this route with tickets for a flight from Winston Salem, NC to Frederick, MD costing on average $609 (€498).
Other travel options to Frederick, MD take longer:
Bus takes on average 10h 48m.
Tickets start at around $107 (€87) compared to roughly $67 (€55) in fuel and tolls — a saving of about $-39.97 (€-32.68). The journey takes 10h 48m versus 5h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Winston Salem, NC to Frederick, MD Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:10AM | Arrival Time 07:25PM | Duration 12h15 | Departure days Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 08:30AM | Duration 14h35 | Departure days Sat | Cheapest price $88 |
Why should you book Winston Salem, NC to Frederick, MD buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Winston Salem, NC to Frederick, MD.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Winston Salem, NC to Frederick, MD.
Journey information
Overview: Bus from Winston Salem, NC to Frederick, MD
USAUSA
Buses from Winston Salem, NC to Frederick, MD run on average 2 times per day, taking around 10h 48m. Cheap bus tickets for this journey start at $100 (€82) if you book in advance.
The earliest bus runs at 11:10, the last at 21:55. The fastest bus covers the 276 miles (445 km) distance in 10h 45m.
Distance 276 miles (445 km) |
Average bus duration 10h 48m |
Cheapest ticket price $100 (€82) |
Buses per day 2 |
Fastest bus 10h 45m |
First bus 11:10 AM |
Last bus 9:55 PM |
High Season Jul - Sep |
Low Season Jul - Sep |
Bus providers: Greyhound, FlixBus from Winston Salem, NC to Frederick, MDYou can travel by bus between Winston Salem, NC to Frederick, MD with Greyhound, FlixBus for as low as $100 (€82). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Winston Salem, NC to Frederick, MD
Find answers to the most common questions about traveling from Winston Salem, NC to Frederick, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frederick, MD, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Winston Salem, NC to Frederick, MD
Most Winston Salem, NC to Frederick, MD buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Frederick, East Street (Transit Center) station pair. Use this guide to compare Winston Salem, NC and Frederick, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Winston Salem, NC station do buses to Frederick, MD leave from?
Getting to Winston Salem, W 5th St (Greyhound Bus Station) from Winston Salem city centre
Winston Salem, W 5th St (Greyhound Bus Station) bus station facilities and services
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Which Frederick, MD station do buses from Winston Salem, NC arrive at?
Getting to Frederick, East Street (Transit Center) from Frederick city centre
Frederick, East Street (Transit Center) bus station facilities and services
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Tickets and information
Ticket office support is available at Frederick, East Street (Transit Center).
Parking, taxis and toilets
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Most popular bus connections from Winston Salem, NC
More options for your journey from Winston Salem, NC to Frederick, MD
Here are some other resources that might have the information you need
Most popular buses to and from Frederick, MD and Winston Salem, NC
Most popular bus connections to Frederick, MD
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