- Recommended
Spartanburg Science Center
Science and history museum with regional exhibits, a planetarium, and family-friendly programs in downtown Spartanburg.
Take a bus from Winston Salem, NC to Spartanburg, SC and enjoy the approximately 123 miles (199 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 03:04, the last at 21:05.
Distance 123 miles (199 km) |
First bus 3:04 AM |
Last bus 9:05 PM |
Cheapest Month Jan |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jan - Mar |
Busiest Day Sat |
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Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Winston Salem, NC to Spartanburg, SC.
Discover the best of Spartanburg, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Spartanburg, SC trip today.
Science and history museum with regional exhibits, a planetarium, and family-friendly programs in downtown Spartanburg.
Art museum and gallery space on the Chapman Cultural Center campus, featuring rotating exhibitions and local artists.
Rail museum with historic locomotives, cars, and exhibits on regional railroad history near downtown Spartanburg.
Central downtown square with shops, public art, seating, and frequent events; a practical starting point for exploring Spartanburg.
Popular urban greenway for walking and cycling, linking downtown with parks, public art, and neighborhood views.
Large city park with trails, sports areas, gardens, and open space for a relaxed outdoor break close to downtown.
South Carolina-style pulled pork smoked low and slow, then finished with a tangy mustard barbecue sauce common across the Upstate and Midlands.
Pork shoulder smoked whole over wood, then chopped or pulled. It is a cornerstone of local barbecue culture in Spartanburg and the Upstate.
Stone-ground corn grits simmered until creamy, often served at breakfast or with seafood. Grits are a longstanding Southern staple in local homes and diners.
Upscale downtown restaurant focused on contemporary American dishes, steaks, and cocktails in a polished historic space.
Established Southern meat-and-three restaurant with fried chicken, vegetables, casseroles, and homestyle desserts in a simple setting.
Lively neighborhood restaurant serving burgers, sandwiches, salads, and broad craft beer selection in a relaxed downtown setting.
Moderate for a U.S. city. Hotels and dining are usually cheaper than major metros, but car use and limited transit can raise total trip costs.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or cafe order if there is table service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Spartanburg, SC.
Find answers to the most common questions about traveling from Winston Salem, NC to Spartanburg, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Spartanburg, SC, this guide helps you travel smarter and with confidence.

Most Winston Salem, NC to Spartanburg, SC buses use the Winston Salem, W 5th St (Greyhound Bus Station) to station pair. Use this guide to compare Winston Salem, NC and Spartanburg, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
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