The cheapest and fastest trains from St. Louis, MO to San Diego, CA
Cheapest price
$2047
Average price
$2047
Fastest journey
2 d 8 h 18 m
Average duration
2 d 8 h 18 m
Trains per day
1
Distance
2512 km
The best way to find a cheap train ticket from St. Louis, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Diego, CA will cost around $2047 if you buy it on the day, but the cheapest tickets can be found for only $2047.
Of the 1 trains that leave St. Louis, MO for San Diego, CA on Mon, Dec 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct trains cover the 2512 km distance in an average of 2 d 8 h 18 m but if you time it right, some trains will get you there in just 2 d 8 h 18 m .
On Mon, Dec 22 the slowest trains will take 2 d 8 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for St. Louis, MO to San Diego, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €120. For those with little time consider booking a flight which can get you there in 8h 8m. The ticket price range depends on the travel mode: a bus costs an average of €120, and a train costs an average of €193.
Distance: 1560 miles (2512 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€291 Average price | €206 Average price Cheapest | €258 Average price |
60h 3m Average total duration 59h 33m Onboard + 30m Additional time* | 51h 34m Average total duration 51h 4m Onboard + 30m Additional time* | 11h 8m Average total duration Fastest 8h 8m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Why should you book St. Louis to San Diego trains with Omio?
Amtrak operates all train services from St. Louis to San Diego. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis to San Diego.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis to San Diego.
Journey information
Overview: Train from St. Louis, MO to San Diego, CA
Trains from St. Louis, MO to San Diego, CA run on average 3 times per day, taking around 59h 33m. Cheap train tickets for this journey start at $240 (€193) but you can travel from only $124 (€99) by flight.
The earliest train runs at 06:35, the last at 19:42. The fastest train covers the 1560 miles (2512 km) distance in 56h 18m.
Distance 1560 miles (2512 km) |
Average train duration 59h 33m |
Cheapest ticket price $240 (€193) |
Trains per day 3 |
Fastest train 56h 18m |
First train 06:35 |
Last train 19:42 |
Train companies: Amtrak from St. Louis, MO to San Diego, CA trainsAmtrak trains will get you between St. Louis, MO and San Diego, CA from $124 (€99). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to San Diego, CA
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to San Diego, CA
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
- 5:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with various public and private options.
- The Fish Market
- Karl Strauss Brewing Company
- Outside the main entrance.
- Ramps.
- $1.25
- The Westin San Diego
- The Guild Hotel, San Diego, a Tribute Portfolio Hotel
- Embassy Suites by Hilton San Diego Bay Downtown
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platforms for Amtrak and Coaster trains
- Hall 2: Trolley connections
- San Diego Trolley: Blue Line, Green Line
- Bus: Several lines available
- Amtrak: Pacific Surfliner
- 6:00 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available with several spaces for commuters and visitors.
- Casa Guadalajara
- Old Town Mexican Cafe
- Outside the main entrance.
- Elevators, ramps.
- $0.25
- Old Town Inn
- Fairfield Inn & Suites by Marriott San Diego Old Town
- Best Western Plus Hacienda Hotel Old Town
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platforms for Amtrak and Coaster trains
- Hall 2: Trolley connections
- Trolley: Green Line
- Bus: Several lines available including 8, 9, 10, 28, 30, 35, 44, 88, 105, 150, 923, 928
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Diego, CA
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