- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
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The cheapest and fastest trains from St. Louis, MO to San Diego, CA
Showing times and prices for Aug 05
Cheapest price
€194
Average price
€194
Fastest journey
2 d 8 h 18 m
Average duration
2 d 8 h 18 m
Trains per day
1
Distance
2512 km
Cheap tickets
The best way to find a cheap train ticket from St. Louis, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Diego, CA will cost around €194 if you buy it on the day, but the cheapest tickets can be found for only €194.
Fast trains
Of the 1 trains that leave St. Louis, MO for San Diego, CA on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct trains cover the 2512 km distance in an average of 2 d 8 h 18 m but if you time it right, some trains will get you there in just 2 d 8 h 18 m .
On Wed, Aug 05 the slowest trains will take 2 d 8 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:35 AM56h18St. Louis, MO7:53 PMSan Diego, CA€1941One-way0 transfers
- 11:35 AM56h18St. Louis, MO7:53 PMSan Diego, CA€1941One-way0 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to San Diego, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price take the flight with prices starting from €120. For those with little time consider booking a flight which can get you there in 7h 22m. The ticket price range depends on the travel mode: a flight costs an average of €120, and a train costs an average of €176.
Distance: 1560 miles (2512 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€227 Average price | €225 Average price | €214 Average price Cheapest | €311 Average price (fuel + tolls) |
61h 41m Average total duration 61h 11m Onboard + 30m Additional time* | 39h 10m Average total duration 38h 40m Onboard + 30m Additional time* | 10h 22m Average total duration Fastest 7h 22m Onboard + 3h 0m Additional time* | 26h 33m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to San Diego, CA is a flight with an average price of €214.
This is compared to other travel options from St. Louis, MO to San Diego, CA:
A flight is €11 less than a bus for this route with tickets for a bus from St. Louis, MO to San Diego, CA costing on average €225.
A flight is €13 less than a train for this route with tickets for a train from St. Louis, MO to San Diego, CA costing on average €227.
The fastest way to travel from St. Louis, MO to San Diego, CA is by flight with an average journey time of 7h 22m.
Other travel options to San Diego, CA take longer:
Bus takes on average 38h 40m.
Train takes on average 61h 11m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Diego, CA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to San Diego, CA among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around €227 compared to roughly €311 in fuel and tolls — a saving of about €84. The journey takes 61h 11m versus 26h 33m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Aug 05
Aug 05
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Journey information
Overview: Train from St. Louis, MO to San Diego, CA
USAUSA
Trains from St. Louis, MO to San Diego, CA run on average 3 times per day, taking around 61h 11m. Cheap train tickets for this journey start at €176 but you can travel from only €111 by bus.
The earliest train runs at 06:35, the last at 19:42. The fastest train covers the 1560 miles (2512 km) distance in 56h 18m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €111
Distance 1560 miles (2512 km) |
Average train duration 61h 11m |
Cheapest ticket price €176 |
Trains per day 3 |
Fastest train 56h 18m |
First train 6:35 AM |
Last train 7:42 PM |
Cheapest Month Apr |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €111
Train companies: Amtrak from St. Louis, MO to San Diego, CA trainsAmtrak trains will get you between St. Louis, MO and San Diego, CA from €111. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
56h 18m
Cheapest Price
€176
Amtrak frequency
1 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to San Diego, CA
Things to do in San Diego, CA
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
- Must visit
Museum of Contemporary Art San Diego
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
- Must visit
USS Midway Museum
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
- Must visit
Balboa Park
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
- Must visit
Gaslamp Quarter
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
- Must visit
La Jolla Cove
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
Fish Taco
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
California Burrito
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
- Gluten-free
Sea Urchin (Uni)
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Sushi Ota
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Mitch's Seafood
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Juniper and Ivy
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
US Dollar ($)
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a mid-range meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
FAQs: Trains from St. Louis, MO to San Diego, CA
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
Train ticket prices from St. Louis, MO to San Diego, CA can vary. The cheapest ticket starts at €176, while the average price is around €227.
The train from St. Louis, MO to San Diego, CA takes 56h 18m and runs 3 per day.
The distance by train from St. Louis, MO to San Diego, CA is 1560 miles (2512 km).
The first train from St. Louis, MO to San Diego, CA leaves at 6:35 AM.
The last train from St. Louis, MO to San Diego, CA leaves at 7:42 PM.
There is no high speed train available from St. Louis, MO to San Diego, CA.
There is no direct train service currently available from St. Louis, MO to San Diego, CA.
Unfortunately, there is no night train available from St. Louis, MO to San Diego, CA.
The train station in St. Louis, MO that goes to San Diego, CA is St. Louis Station, St. Louis, MO, which connects to Santa Fe Depot, San Diego, CA.
The cheapest way to get from St. Louis, MO to San Diego, CA is by bus, with a cost of around €111.
The train journey from St. Louis, MO to San Diego, CA offers scenic views, particularly as it passes through diverse landscapes such as the expansive plains of the Midwest, the rugged terrain of New Mexico, and the picturesque desert vistas of Arizona, providing passengers with a varied and visually appealing travel experience.
A day trip from St. Louis, MO to San Diego, CA is not feasible, as the journey takes 56h 18m and covers 1560 miles (2512 km). There are 3 trips per day by train.
In San Diego, CA, you can explore the vibrant art scene at the Museum of Contemporary Art, enjoy a harbor cruise for stunning skyline and naval ship views, and hike the scenic trails at Torrey Pines State Natural Reserve. Visit the Birch Aquarium to learn about marine life, or experience a whale watching tour off the coast. Don't miss Balboa Park, with its museums and the San Diego Zoo, the historic USS Midway Museum, picturesque La Jolla Cove, the lively Gaslamp Quarter, and the beautiful Coronado Beach.
Three to four days are ideal to explore San Diego's main attractions, including its beaches, Balboa Park, San Diego Zoo, and vibrant neighborhoods.
Yes, you can take the train from St. Louis, MO to San Diego, CA.
Since neither St. Louis, MO nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from San Diego, CA include Irvine, CA, Santa Ana, CA, Oceanside, CA, Orange, CA, San Juan Capistrano, CA.
We recommend using the train as it is the most popular way to get from St. Louis, MO to San Diego, CA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from St. Louis, MO to San Diego, CA
Most St. Louis, MO to San Diego, CA trains use the St. Louis Station to Santa Fe Depot station pair, with some services arriving at Old Town Station. Use this guide to compare St. Louis, MO and San Diego, CA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in St. Louis
Arrival train stations in San Diego
Which St. Louis, MO station do trains to San Diego, CA leave from?
Trains from St. Louis, MO to San Diego, CA leave from St. Louis Station. The station is 0 miles (1 km) from St. Louis, MO city centre at 430 S 15th St, St. Louis, MO 63103, USA.
St. Louis Station430 S 15th St, St. Louis, MO 63103, USA+1 800-872-7245
City-centre transport
Getting to St. Louis Station from St. Louis city centre
TrainMlb, Mlr · 3m · €3 · every ~14 min
St. Louis Station train station facilities and services
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Landry's Seafood House, The Station Grille
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at St. Louis Station: Parking, Taxis, WC.
Bike and car services
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Which San Diego, CA station do trains from St. Louis, MO arrive at?
Trains from St. Louis, MO to San Diego, CA most often arrive at Santa Fe Depot. Some services arrive at Old Town Station, so check your ticket before travel to confirm your San Diego, CA arrival station.
Santa Fe Depot1050 Kettner Blvd, San Diego, CA 92101, USA+1 800-872-7245
City-centre transport
Getting to Santa Fe Depot from San Diego city centre
Santa Fe Depot is 1 km from San Diego city centre. Public transport options include:
Bus215, 225, 235, 910 · 5m · €5 · every ~22 min
TramBlue, Orange · 2m · every ~15 min
Santa Fe Depot train station facilities and services
Santa Fe Depot has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: The Fish Market, Karl Strauss Brewing Company
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Santa Fe Depot. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Santa Fe Depot. Lost and found is available at the station.
Parking, taxis and toilets
Available at Santa Fe Depot: Parking, Taxis, WC.
Bike and car services
Available at Santa Fe Depot: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Santa Fe Depot: Ramps.
Shops, hotels and contact
Nearby hotels include The Westin San Diego, The Guild Hotel, San Diego, a Tribute Portfolio Hotel, Embassy Suites by Hilton San Diego Bay Downtown.
Old Town Station4009 Taylor Street, San Diego, CA 92110, United States
City-centre transport
Getting to Old Town Station from San Diego city centre
Old Town Station is 5 km from San Diego city centre. Public transport options include:
TrainCoaster · 7m · €6 · every ~2 min
Pacific Surfliner · 7m · €1 · every ~2 min
BusFlixBus 2017 · 15m · €1
83 · 26m · €5
TramGreen, Blue, Event · 9m · every ~18 min
Blue · 14m · every ~9 min
Old Town Station train station facilities and services
Old Town Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Casa Guadalajara, Old Town Mexican Cafe
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Old Town Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Old Town Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Old Town Station: Parking, Taxis, WC.
Bike and car services
Available at Old Town Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Old Town Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Old Town Inn, Fairfield Inn & Suites by Marriott San Diego Old Town, Best Western Plus Hacienda Hotel Old Town.
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Diego, CA
Here are some other resources that might have the information you need
Most popular trains to and from San Diego, CA and St. Louis, MO
Most popular train connections to San Diego, CA
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