St. Louis, MO to San Diego, CA train

Sat, Sep 19
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Regionale
Deutsche Bahn
iryo
Frecciarossa
AVE
2,000+ travel companies
Regionale
Deutsche Bahn
iryo
Frecciarossa
AVE
2,000+ travel companies
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Travel Information

Compare train, bus, and flight for St. Louis, MO to San Diego, CA

Omio recommends booking the flight as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $347 For those with little time, consider booking a flight, which has an average total journey time of 8h 36m. Average ticket prices depend on the travel mode: a bus costs an average of $347, while a flight costs an average of $595.

Distance: 1560 miles (2512 km)

Compare flight with

Most popular
Flight
Bus
Driving

$595

Average price

$347

Average price

Cheapest

$384

Average price

(fuel + tolls)

8h 36m

Average total duration

Fastest

6h 36m

Onboard

+

2h 0m

Additional time*

42h 0m

Average total duration

41h 30m

Onboard

+

30m

Additional time*

26h 33m

Average total duration

(door-to-door)

United

Most popular airline

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from St. Louis, MO to San Diego, CA is a bus with an average price of $347 (€284).

This is compared to other travel options from St. Louis, MO to San Diego, CA:

A bus is $248 (€202) less than a flight for this route with tickets for a flight from St. Louis, MO to San Diego, CA costing on average $595 (€487).

The fastest way to travel from St. Louis, MO to San Diego, CA is by flight with an average journey time of 6h 36m.

Other travel options to San Diego, CA take longer:

Bus takes on average 41h 30m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Diego, CA including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to San Diego, CA among Omio's users.

Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Train from St. Louis, MO to San Diego, CA

USAUSA
USAUSA
Icon of train

Take a train from St. Louis, MO to San Diego, CA and enjoy the approximately 1560 miles (2512 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 06:35, the last at 19:42.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $255 (€208)
Distance
1560 miles (2512 km)
First train
6:35 AM
Last train
7:42 PM
Cheapest Month
Apr
Cheapest Day
Sun
High Season
Oct - Dec
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $255 (€208)

Complete guide to San Diego, CA

Things to do in San Diego, CA

Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.

  • Must visit

San Diego Museum of Art

Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.

  • Must visit

Museum of Contemporary Art San Diego

Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.

  • Must visit

USS Midway Museum

Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.

US Dollar ($)

San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$25-45 per person for a mid-range meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$4-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.

FAQs: Trains from St. Louis, MO to San Diego, CA

Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from St. Louis, MO to San Diego, CA is 1560 miles (2512 km).
The first train from St. Louis, MO to San Diego, CA leaves at 6:35 AM.
The last train from St. Louis, MO to San Diego, CA leaves at 7:42 PM.
There is no high speed train available from St. Louis, MO to San Diego, CA.
Unfortunately, there is no night train available from St. Louis, MO to San Diego, CA.
The train station in St. Louis, MO that goes to San Diego, CA is St. Louis Station, St. Louis, MO, which connects to Old Town Station, San Diego, CA.
The cheapest way to get from St. Louis, MO to San Diego, CA is by bus, with a cost of around $133 (€108).
The train journey from St. Louis, MO to San Diego, CA offers scenic views, particularly as it passes through diverse landscapes such as the expansive plains of the Midwest, the rugged terrain of New Mexico, and the picturesque desert vistas of Arizona, providing passengers with a varied and visually appealing travel experience.
In San Diego, CA, you can explore the vibrant art scene at the Museum of Contemporary Art, enjoy a harbor cruise for stunning skyline and naval ship views, and hike the scenic trails at Torrey Pines State Natural Reserve. Visit the Birch Aquarium to learn about marine life, or experience a whale watching tour off the coast. Don't miss Balboa Park, with its museums and the San Diego Zoo, the historic USS Midway Museum, picturesque La Jolla Cove, the lively Gaslamp Quarter, and the beautiful Coronado Beach.
Three to four days are ideal to explore San Diego's main attractions, including its beaches, Balboa Park, San Diego Zoo, and vibrant neighborhoods.
Yes, you can take the train from St. Louis, MO to San Diego, CA.
Since neither St. Louis, MO nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from San Diego, CA include Irvine, CA, Santa Ana, CA, Oceanside, CA, Orange, CA, San Juan Capistrano, CA.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to San Diego, CA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from St. Louis, MO to San Diego, CA

Most St. Louis, MO to San Diego, CA trains use the St. Louis Station to Old Town Station station pair, with some services arriving at Santa Fe Depot. Use this guide to compare St. Louis, MO and San Diego, CA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in St. Louis
Arrival train stations in San Diego

Which St. Louis, MO station do trains to San Diego, CA leave from?

Trains from St. Louis, MO to San Diego, CA leave from St. Louis Station. The station is 0 miles (1 km) from St. Louis, MO city centre at 430 S 15th St, St. Louis, MO 63103, USA.
St. Louis Station430 S 15th St, St. Louis, MO 63103, USA+1 800-872-7245WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to St. Louis Station from St. Louis city centre

TrainMlb, Mlr · 3m · $4 · every ~14 min

St. Louis Station train station facilities and services

St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.

Food and drink

Food options include: Landry's Seafood House, The Station Grille

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at St. Louis Station. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at St. Louis Station. Lost and found is available at the station.

Parking, taxis and toilets

Available at St. Louis Station: Parking, Taxis, WC.

Bike and car services

Available at St. Louis Station: Bike Parking, Car Rental.

Accessibility

Accessibility facilities are available at St. Louis Station: Ramps, restrooms.

Shops, hotels and contact

Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.

More options for your journey from St. Louis, MO to San Diego, CA

Here are some other resources that might have the information you need

Most popular trains to and from San Diego, CA and St. Louis, MO

HomeTrainsTrains in USATrain Times to San Diego, CASt. Louis, MO to San Diego, CA train

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