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Journey information
Overview: St. Louis, MO to San Diego, CA flight
USAUSA
Flights from St. Louis, MO to San Diego, CA depart on average 54 times per day, taking around 7h 22m. Cheap flight tickets for this journey start at $185 (€151) but you can travel from only $151 (€124) by bus.
The earliest flight runs at 05:00, the last at 22:49. The fastest flight covers the 1560 miles (2512 km) distance in 5h 54m. August is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $151 (€124)
Distance 1560 miles (2512 km) |
Average flight duration 7h 22m |
Cheapest ticket price $185 (€151) |
Flights per day 54 |
Fastest flight 5h 54m |
First flight 05:00 |
Last flight 22:49 |
Cheapest month Aug |
Cheapest day Wed |
High season Oct - Dec |
Low season Apr - Jun |
Best day to book ahead 6 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $151 (€124)
The cheapest and fastest flights from St. Louis, MO to San Diego, CA
Showing times and prices for Mar 18
Cheapest price
$268
Average price
$307
Fastest journey
7 h 10 m
Average duration
12 h 25 m
Flights per day
2
Distance
2512 km
Cheap tickets
The best way to find a cheap flight ticket from St. Louis, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Diego, CA will cost around $307 if you buy it on the day, but the cheapest tickets can be found for only $268.
Fast flights
Of the 2 flights that leave St. Louis, MO for San Diego, CA onWed, Mar 18, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Mar 18 the direct flights cover the 2512 km distance in an average of 12 h 25 m but if you time it right, some flights will get you there in just 7 h 10 m .
On Wed, Mar 18 the longest flights will take 17 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:05AM17h40
St. Louis, MO04:45AMSan Diego, CA
$2681One-way
0 transfers
09:38PM7h10
St. Louis, MO04:48AMSan Diego, CA
$3471One-way
0 transfers
09:38PM7h10
St. Louis, MO04:48AMSan Diego, CA
$3471One-way
0 transfers
11:05AM17h40
St. Louis, MO04:45AMSan Diego, CA
$2681One-way
0 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to San Diego, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $151. For those with little time consider booking a flight which can get you there in 7h 22m. The ticket price range depends on the travel mode: a bus costs an average of $151, and a train costs an average of $216.
Distance: 1560 miles (2512 km)
Compare flight with
| Flight | Most popular Train | Bus |
|---|---|---|
$335 Average price | $670 Average price | $303 Average price Cheapest |
10h 22m Average total duration Fastest 7h 22m Onboard + 3h 0m Additional time* | 60h 54m Average total duration 60h 24m Onboard + 30m Additional time* | 50h 1m Average total duration 49h 31m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to San Diego, CA flights with Omio?
American Airlines operates all flights services from St. Louis, MO to San Diego, CA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to San Diego, CA.
Why book with Omio vs American Airlines?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to San Diego, CA.
Why book with Omio over Trip, Edreams or Skyscanner?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to San Diego, CA.
Airlines: American Airlines from St. Louis, MO to San Diego, CAFind the best flights between St. Louis, MO to San Diego, CA with Omio's travel partners American Airlines from $151 (€124). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
5h 54m
Cheapest Price
$185 (€151)
American Airlines frequency
24 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
FAQs: St. Louis, MO to San Diego, CA Flight
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap plane tickets from St. Louis, MO to San Diego, CA can start from as little as $185 (€151) when you book in advance. The average flight ticket price for St. Louis, MO to San Diego, CA is $335 (€274) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from St. Louis, MO to San Diego, CA is 5h 54m to travel the 1560 miles (2512 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from St. Louis, MO to San Diego, CA leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from St. Louis, MO to San Diego, CA leaves at 10:49 PM.
There are 54 flights a day from St. Louis, MO to San Diego, CA which require at least one change with American Airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from St. Louis, MO to San Diego, CA, you can count on American Airlines for the best way to get you to San Diego, CA. You can also check all possible airlines who offer a service between St. Louis, MO and San Diego, CA and compare the amenities they offer before buying a plane ticket.
Flights from St. Louis, MO to San Diego, CA generally leave from St. Louis Lambert International Airport and arrive in San Diego International Airport.St. Louis Lambert International Airport is 1 miles (2 km) away from St. Louis, MO city centre and San Diego International Airport is 2 miles (4 km) from San Diego, CA city centre.
The cheapest month for a flight from St. Louis, MO to San Diego, CA is August.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Diego, CA including taking a train, bus, and flight.
Since neither St. Louis, MO nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 2 h between St. Louis, MO and San Diego, CA all year round.
The best events to attend in San Diego, CA include:
- Comic-Con International, the largest comic book and popular arts convention in the world
- San Diego County Fair, a month-long fair featuring rides, games, and local food
- San Diego Beer Week, a celebration of craft beer with tastings and events across the county
- La Jolla Music Festival, an annual event showcasing classical music performances in a picturesque coastal setting.
The best holidays to experience in San Diego, CA include:
- Memorial Day, ideal weather for beach activities and outdoor events
- Independence Day, spectacular fireworks and patriotic celebrations
- Labor Day, perfect for enjoying the last days of summer at the beach
- Thanksgiving, a time for family gatherings with pleasant fall weather.
The best season to visit San Diego, CA is Spring or Fall. The best weather to explore San Diego, CA is during April-June or September-November.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from St. Louis, MO to San Diego, CA
St. Louis
San Diego
The major airport for departures in St. Louis is St. Louis Lambert International Airport. Find all the information you need to know about services, amenities and connections at St. Louis Lambert International Airport for your trip from St. Louis to San Diego.
Amenities at airport
Wifi
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Car Rentalinformation
Distance to city center
2 km
Car connection
I-70, Exit 236Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in both terminals, including Hudson News and Tech on the Go.
Parking
- Parking available with short-term and long-term options, approximately 1.42€ ($1.50) per hour.
Dining
- Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps
WC
- Available throughout both terminals.
Hotel
- Hotels nearby, such as Marriott St. Louis Airport within walking distance.
Shower
- Showers available in some lounges, access may require lounge fee.
Lounge
- Lounges available, including American Airlines Admirals Club.
Lost and Found Office
- Lost and Found located in terminal 1, contact airport for details.
Car Rental
- Car rental services available, including Hertz and Enterprise in terminal 1
Public transit options for St. Louis Lambert International Airport
- MetroLink Red Line, Lambert Airport terminal 1 & 2 stations, 35 minutes
The major airport for arrivals in San Diego is San Diego International Airport. Find all the information you need to know about services, amenities and connections at San Diego International Airport for your journey to San Diego from St. Louis.
Amenities at airport
WifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rentalinformation
Distance to city center
4 kmCar connection
I-5, exit Sassafras StWifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in terminals 1 and 2, including Duty-Free and Hudson News.
Parking
- Parking available, price varies.
Dining
- Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps
WC
- Available throughout the airport.
Hotel
- Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance.
Shower
- Showers available at the Airspace Lounge, access fee required.
Lounge
- Lounges available, including United Club and Airspace Lounge.
Lost and Found Office
- Lost and Found located in terminal 2 East, baggage claim area.
Car Rental
- Car rental services available at Rental Car Center, free shuttle from terminals
Public transit options for San Diego International Airport
- Bus Route 992, Airport Station, 4.8 km
More options for your journey from St. Louis, MO to San Diego, CA
Here are some other resources that might have the information you need
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Most popular flights to San Diego, CA
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