- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Flights from St. Louis, MO to San Diego, CA depart on average 64 times per day, taking around 6h 37m. Cheap flight tickets for this journey start at €129 but you can travel from only €108 by bus.
The earliest flight runs at 05:00, the last at 22:49. The fastest flight covers the 1560 miles (2512 km) distance in 4h 26m. August is the cheapest month to fly.
Distance 1560 miles (2512 km) |
Average flight duration 6h 37m |
Cheapest ticket price €129 |
Flights per day 64 |
Fastest flight 4h 26m |
First flight 5:00 AM |
Last flight 10:49 PM |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 6 days |
Cheapest price on Sep 15
€132
Average ticket price on Sep 15
€297
Fastest journey on Sep 15
5 h 33 m
Average journey duration on Sep 15
5 h 50 m
Flights on Sep 15
89
Distance
2512 km
The best way to find a cheap flight ticket from St. Louis, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Diego, CA will cost around €297 if you buy it on the day, but the cheapest tickets can be found for only €132.
It's difficult to get from St. Louis, MO to San Diego, CA without transferring at least once.
AA2574 · AA2122
AA1363 · AA1511
AA2261 · AA2034
AA2660 · AA480
AA1363 · AA1243
UA1380 · UA1281
AA2660 · AA480
UA1548 · UA540
AA3333 · AA1769
UA2459 · UA1940Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €280 For those with little time, consider booking a flight, which has an average total journey time of 8h 37m. Average ticket prices depend on the travel mode: a bus costs an average of €280, while a train costs an average of €677.
Distance: 1560 miles (2512 km)
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
€504 Average price | €677 Average price | €280 Average price Cheapest | €314 Average price (fuel + tolls) |
8h 37m Average total duration Fastest 6h 37m Onboard + 2h 0m Additional time* | 51h 35m Average total duration 51h 5m Onboard + 30m Additional time* | 42h 56m Average total duration 42h 26m Onboard + 30m Additional time* | 26h 33m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to San Diego, CA:
A bus is €225 less than a flight for this route with tickets for a flight from St. Louis, MO to San Diego, CA costing on average €504.
A bus is €398 less than a train for this route with tickets for a train from St. Louis, MO to San Diego, CA costing on average €677.
Other travel options to San Diego, CA take longer:
Bus takes on average 42h 26m.
Train takes on average 51h 5m.
The table below shows live departures for St. Louis, MO to San Diego, CA flights for today, Monday, September 14. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AA1515 · AA466 | 6:53 AM St. Louis Lambert International Airport | 8h07 | 1:00 PM San Diego International Airport | 1 transfer | |
AA537 · AA3109 | 7:00 AM St. Louis Lambert International Airport | 7h03 | 12:03 PM San Diego International Airport | 1 transfer | |
AA1997 · AA2131 | 7:21 AM St. Louis Lambert International Airport | 6h54 | 12:15 PM San Diego International Airport | 1 transfer | |
AA2574 · AA2122 | 8:00 AM St. Louis Lambert International Airport | 6h03 | 12:03 PM San Diego International Airport | 1 transfer | |
UA2749 · UA1049 · UA582 | 8:00 AM St. Louis Lambert International Airport | 11h26 | 5:26 PM San Diego International Airport | 2 transfers | |
UA3674 · UA1079 | 8:20 AM St. Louis Lambert International Airport | 13h33 | 7:53 PM San Diego International Airport | 1 transfer | |
UA4601 · UA1363 · UA582 | 8:30 AM St. Louis Lambert International Airport | 10h56 | 5:26 PM San Diego International Airport | 2 transfers | |
UA4595 · UA2399 | 8:35 AM St. Louis Lambert International Airport | 6h42 | 1:17 PM San Diego International Airport | 1 transfer | |
UA4506 · UA2163 | 8:40 AM St. Louis Lambert International Airport | 8h17 | 2:57 PM San Diego International Airport | 1 transfer | |
UA2100 · UA5508 | 8:42 AM St. Louis Lambert International Airport | 14h03 | 8:45 PM McClellan–Palomar Airport | 1 transfer | |
UA2100 · UA1561 | 8:42 AM St. Louis Lambert International Airport | 11h53 | 6:35 PM San Diego International Airport | 1 transfer | |
UA2100 · UA1668 | 8:42 AM St. Louis Lambert International Airport | 9h12 | 3:54 PM San Diego International Airport | 1 transfer | |
UA2100 · UA1257 | 8:42 AM St. Louis Lambert International Airport | 7h02 | 1:44 PM San Diego International Airport | 1 transfer | |
UA2459 · UA5507 | 9:00 AM St. Louis Lambert International Airport | 6h04 | 1:04 PM McClellan–Palomar Airport | 1 transfer | |
UA2459 · UA1940 | 9:00 AM St. Louis Lambert International Airport | 6h01 | 1:01 PM San Diego International Airport | 1 transfer | |
UA4395 · UA1363 · UA582 | 9:40 AM St. Louis Lambert International Airport | 9h46 | 5:26 PM San Diego International Airport | 2 transfers | |
AA3333 · AA1789 | 10:14 AM St. Louis Lambert International Airport | 10h37 | 6:51 PM San Diego International Airport | 1 transfer | |
AA3333 · AA1769 | 10:14 AM St. Louis Lambert International Airport | 5h57 | 2:11 PM San Diego International Airport | 1 transfer | |
UA4517 · UA2188 | 10:53 AM St. Louis Lambert International Airport | 6h56 | 3:49 PM San Diego International Airport | 1 transfer | |
AA2818 · AA2994 | 11:01 AM St. Louis Lambert International Airport | 14h24 | 11:25 PM San Diego International Airport | 1 transfer | |
AA2818 · AA1543 | 11:01 AM St. Louis Lambert International Airport | 8h28 | 5:29 PM San Diego International Airport | 1 transfer | |
AA2818 · AA1861 | 11:01 AM St. Louis Lambert International Airport | 12h29 | 9:30 PM San Diego International Airport | 1 transfer | |
UA5589 · UA1276 | 11:15 AM St. Louis Lambert International Airport | 8h31 | 5:46 PM San Diego International Airport | 1 transfer | |
UA560 · UA2825 | 12:28 PM St. Louis Lambert International Airport | 12h21 | 10:49 PM San Diego International Airport | 1 transfer | |
UA560 · UA1079 | 12:28 PM St. Louis Lambert International Airport | 9h25 | 7:53 PM San Diego International Airport | 1 transfer | |
AA1789+ AA4074 | 12:46 PM St. Louis Lambert International Airport | 8h05 | 6:51 PM San Diego International Airport | 1 transfer | |
AA2266+ AA4074 | 12:46 PM St. Louis Lambert International Airport | 7h01 | 5:47 PM San Diego International Airport | 1 transfer | |
AA1243+ AA4074 | 12:46 PM St. Louis Lambert International Airport | 9h15 | 8:01 PM San Diego International Airport | 1 transfer | |
UA2779 · UA576 · UA1100 | 12:59 PM St. Louis Lambert International Airport | 9h03 | 8:02 PM San Diego International Airport | 2 transfers | |
UA2779 · UA2769 · UA540 | 12:59 PM St. Louis Lambert International Airport | 9h35 | 8:34 PM San Diego International Airport | 2 transfers | |
UA4454 · UA2054 | 1:00 PM St. Louis Lambert International Airport | 9h29 | 8:29 PM San Diego International Airport | 1 transfer | |
UA1380 · UA1195 · UA1100 | 1:36 PM St. Louis Lambert International Airport | 8h26 | 8:02 PM San Diego International Airport | 2 transfers | |
UA1380 · UA1281 | 1:36 PM St. Louis Lambert International Airport | 5h34 | 5:10 PM San Diego International Airport | 1 transfer | |
UA1380 · UA5529 | 1:36 PM St. Louis Lambert International Airport | 9h16 | 8:52 PM McClellan–Palomar Airport | 1 transfer | |
AA1861+ AA6355 | 1:49 PM St. Louis Lambert International Airport | 9h41 | 9:30 PM San Diego International Airport | 1 transfer | |
AA2994+ AA6355 | 1:49 PM St. Louis Lambert International Airport | 11h36 | 11:25 PM San Diego International Airport | 1 transfer | |
AA3096 · AA562 | 1:54 PM St. Louis Lambert International Airport | 7h23 | 7:17 PM San Diego International Airport | 1 transfer | |
AA2660 · AA480 | 2:30 PM St. Louis Lambert International Airport | 5h46 | 6:16 PM San Diego International Airport | 1 transfer | |
UA4060 · UA1911 | 3:13 PM St. Louis Lambert International Airport | 8h11 | 9:24 PM San Diego International Airport | 1 transfer | |
AA7550 · AA9271 | 3:19 PM St. Louis Lambert International Airport | 7h57 | 9:16 PM San Diego International Airport | 1 transfer | |
UA4500 · UA2022 | 3:32 PM St. Louis Lambert International Airport | 8h38 | 10:10 PM San Diego International Airport | 1 transfer | |
AA1363 · AA1243 | 3:34 PM St. Louis Lambert International Airport | 6h27 | 8:01 PM San Diego International Airport | 1 transfer | |
AA1363 · AA1511 | 3:34 PM St. Louis Lambert International Airport | 8h14 | 9:48 PM San Diego International Airport | 1 transfer | |
UA1548 · UA5529 | 4:40 PM St. Louis Lambert International Airport | 6h12 | 8:52 PM McClellan–Palomar Airport | 1 transfer | |
UA1548 · UA540 | 4:40 PM St. Louis Lambert International Airport | 5h54 | 8:34 PM San Diego International Airport | 1 transfer | |
UA1548 · UA1389 | 4:40 PM St. Louis Lambert International Airport | 9h49 | 12:29 AM San Diego International Airport | 1 transfer | |
AA1511+ AA3739 | 5:11 PM St. Louis Lambert International Airport | 6h37 | 9:48 PM San Diego International Airport | 1 transfer | |
AA2994+ AA4645 | 5:18 PM St. Louis Lambert International Airport | 8h07 | 11:25 PM San Diego International Airport | 1 transfer | |
UA541 · UA2022 | 5:30 PM St. Louis Lambert International Airport | 6h40 | 10:10 PM San Diego International Airport | 1 transfer | |
| Tuesday, September 15 | |||||
AA1926 · AA2131 | 5:00 AM St. Louis Lambert International Airport | 9h15 | 12:15 PM San Diego International Airport | 1 transfer | |
AA2261 · AA2034 | 5:43 AM St. Louis Lambert International Airport | 6h42 | 10:25 AM San Diego International Airport | 1 transfer | |
AA2261 · AA3109 | 5:43 AM St. Louis Lambert International Airport | 8h20 | 12:03 PM San Diego International Airport | 1 transfer | |
AA2261 · AA520 · AA2122 | 5:43 AM St. Louis Lambert International Airport | 8h20 | 12:03 PM San Diego International Airport | 2 transfers | |
UA6258 · UA2399 | 6:15 AM St. Louis Lambert International Airport | 9h02 | 1:17 PM San Diego International Airport | 1 transfer | |
UA6258 · UA2491 | 6:15 AM St. Louis Lambert International Airport | 6h43 | 10:58 AM San Diego International Airport | 1 transfer | |
AS473 · AS688 · AS3099 | 6:29 AM St. Louis Lambert International Airport | 12h41 | 5:10 PM San Diego International Airport | 2 transfers | |
AS473 · AS533 · AS3103 | 6:29 AM St. Louis Lambert International Airport | 12h21 | 4:50 PM San Diego International Airport | 2 transfers | |
AS473 · AS658 · AS2322 | 6:29 AM St. Louis Lambert International Airport | 11h23 | 3:52 PM San Diego International Airport | 2 transfers | |
AS473 · AS3145 · AS425 | 6:29 AM St. Louis Lambert International Airport | 13h07 | 5:36 PM San Diego International Airport | 2 transfers | |
AS473 · AS655 · AS1326 | 6:29 AM St. Louis Lambert International Airport | 14h31 | 7:00 PM San Diego International Airport | 2 transfers | |
AS473 · AS658 · AS2220 | 6:29 AM St. Louis Lambert International Airport | 14h04 | 6:33 PM San Diego International Airport | 2 transfers | |
AS473 · AS2106 · AS3481 | 6:29 AM St. Louis Lambert International Airport | 15h50 | 8:19 PM San Diego International Airport | 2 transfers | |
AS473 · AS533 · AS2103 | 6:29 AM St. Louis Lambert International Airport | 14h14 | 6:43 PM San Diego International Airport | 2 transfers | |
AS473 · AS488 · AS425 | 6:29 AM St. Louis Lambert International Airport | 13h07 | 5:36 PM San Diego International Airport | 2 transfers | |
AS473 · AS488 · AS667 | 6:29 AM St. Louis Lambert International Airport | 15h52 | 8:21 PM San Diego International Airport | 2 transfers | |
AS473 · AS383 · AS3388 | 6:29 AM St. Louis Lambert International Airport | 13h18 | 5:47 PM San Diego International Airport | 2 transfers | |
AS473 · AS738 · AS3011 | 6:29 AM St. Louis Lambert International Airport | 14h24 | 6:53 PM San Diego International Airport | 2 transfers | |
AS473 · AS597 · AS3481 | 6:29 AM St. Louis Lambert International Airport | 15h50 | 8:19 PM San Diego International Airport | 2 transfers | |
AS473 · AS763 · AS2218 | 6:29 AM St. Louis Lambert International Airport | 14h08 | 6:37 PM San Diego International Airport | 2 transfers | |
AS473 · AS288 · AS2218 | 6:29 AM St. Louis Lambert International Airport | 14h08 | 6:37 PM San Diego International Airport | 2 transfers | |
AS473 · AS275 · AS2415 | 6:29 AM St. Louis Lambert International Airport | 11h27 | 3:56 PM San Diego International Airport | 2 transfers | |
AS473 · AS612 · AS3011 | 6:29 AM St. Louis Lambert International Airport | 14h24 | 6:53 PM San Diego International Airport | 2 transfers | |
AS473 · AS697 | 6:29 AM St. Louis Lambert International Airport | 8h52 | 1:21 PM San Diego International Airport | 1 transfer | |
AS473 · AS688 · AS1326 | 6:29 AM St. Louis Lambert International Airport | 14h31 | 7:00 PM San Diego International Airport | 2 transfers | |
AA7628 · AA7486 | 6:29 AM St. Louis Lambert International Airport | 8h52 | 1:21 PM San Diego International Airport | 1 transfer | |
AS473 · AS621 | 6:29 AM St. Louis Lambert International Airport | 10h13 | 2:42 PM San Diego International Airport | 1 transfer | |
AS473 · AS2191 · AS2318 | 6:29 AM St. Louis Lambert International Airport | 12h27 | 4:56 PM San Diego International Airport | 2 transfers | |
AS473 · AS3145 · AS1312 | 6:29 AM St. Louis Lambert International Airport | 12h07 | 4:36 PM San Diego International Airport | 2 transfers | |
AS473 · AS1321 · AS3046 | 6:29 AM St. Louis Lambert International Airport | 16h07 | 8:36 PM San Diego International Airport | 2 transfers | |
AS473 · AS763 · AS3439 | 6:29 AM St. Louis Lambert International Airport | 10h07 | 2:36 PM San Diego International Airport | 2 transfers | |
AS473 · AS612 · AS2410 | 6:29 AM St. Louis Lambert International Airport | 11h42 | 4:11 PM San Diego International Airport | 2 transfers | |
AS473 · AS655 · AS3099 | 6:29 AM St. Louis Lambert International Airport | 12h41 | 5:10 PM San Diego International Airport | 2 transfers | |
AS473 · AS3145 · AS667 | 6:29 AM St. Louis Lambert International Airport | 15h52 | 8:21 PM San Diego International Airport | 2 transfers | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to San Diego, CA flights use the St. Louis Lambert International Airport to San Diego International Airport airport pair, with some services landing at McClellan-Palomar Airport. Use this guide to compare St. Louis, MO and San Diego, CA airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
St. Louis Lambert International Airport is 2 km from St. Louis city centre. Public transport options include:
St. Louis Lambert International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
Free Wi-Fi available throughout the airport. ATMs are located in both terminals.
Lost and found is available at the station.
Available at St. Louis Lambert International Airport: Parking, Taxis, WC.
Available at St. Louis Lambert International Airport: Car Rental.
Accessibility facilities are available at St. Louis Lambert International Airport: Elevators, ramps.
Nearby hotels include Hotels nearby, such as Marriott St. Louis Airport within walking distance..
San Diego International Airport is 4 km from San Diego city centre. Public transport options include:
San Diego International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Lost and found is available at the station.
Available at San Diego International Airport: Parking, Taxis, WC.
Available at San Diego International Airport: Car Rental.
Accessibility facilities are available at San Diego International Airport: Elevators, ramps.
Nearby hotels include Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance..
McClellan-Palomar Airport has practical services for this route, including Accessibility.
Accessibility facilities are available at McClellan-Palomar Airport: The place has an entrance that is wheelchair-accessible.
Here are some other resources that might have the information you need