Jacksonville, FL to St. Louis, MO bus

Sat, Feb 14
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FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Travel Information

Compare bus for Jacksonville, FL to St. Louis, MO

Omio recommends booking the train as it is the most popular option from Jacksonville, FL to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €171. For those with little time consider booking a flight which can get you there in 8h 13m. The ticket price range depends on the travel mode: a bus costs an average of €171, and a train costs an average of €236.

Distance: 751 miles (1209 km)

Compare bus with

Bus
Most popular
Train
Flight

€173

Average price

Cheapest

€236

Average price

€207

Average price

20h 0m

Average total duration

19h 30m

Onboard

+

30m

Additional time*

40h 53m

Average total duration

40h 23m

Onboard

+

30m

Additional time*

11h 13m

Average total duration

Fastest

8h 13m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Journey information

Overview: Bus from Jacksonville, FL to St. Louis, MO

USAUSA
USAUSA
Icon of bus

Buses from Jacksonville, FL to St. Louis, MO run on average 3 times per day, taking around 19h 30m. Cheap bus tickets for this journey start at $216 (€171) if you book in advance.

The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 751 miles (1209 km) distance in 19h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
751 miles (1209 km)
Average bus duration
19h 30m
Cheapest ticket price
$216 (€171)
Buses per day
3
Fastest bus
19h 30m
First bus
02:00
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Jacksonville, FL to St. Louis, MO

Find answers to the most common questions about traveling from Jacksonville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Jacksonville, FL to St. Louis, MO can start from as little as $216 (€171) when you book in advance. The average bus ticket price for Jacksonville, FL to St. Louis, MO is $219 (€173) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Jacksonville, FL to St. Louis, MO is 19h 30m to travel the 751 miles (1209 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Jacksonville, FL to St. Louis, MO leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jacksonville, FL to St. Louis, MO leaves at 11:30 PM.
A trip to St. Louis, MO from Jacksonville, FL is worth doing but not as a day trip with a journey time of 19h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Jacksonville, FL to St. Louis, MO is July.
Yes, you can take a between Jacksonville, FL and St. Louis, MO.
No, the bus from Jacksonville, FL to St. Louis, MO has no accessibility options.
No, there are no bathrooms on board the bus from Jacksonville, FL to St. Louis, MO.
No, bikes are not allowed on board the bus from Jacksonville, FL to St. Louis, MO.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Jacksonville, FL to St. Louis, MO.
No, luggage for the bus from Jacksonville, FL to St. Louis, MO needs to be booked in addition.
No, there are no additional luggage options for the bus from Jacksonville, FL to St. Louis, MO.
Unfortunately, pets are not allowed on the bus from Jacksonville, FL to St. Louis, MO.
No, there are no USB plugs on board the bus from Jacksonville, FL to St. Louis, MO.
No, there is no WiFi on board the bus from Jacksonville, FL to St. Louis, MO.

popular bus stations

Popular bus stations from Jacksonville, FL to St. Louis, MO

Jacksonville
St. Louis
The major bus station for departures in Jacksonville is Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. Find all the information you need to know about services, amenities and connections at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St for your trip from Jacksonville to St. Louis.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
information

Most popular buses to and from St. Louis, MO and Jacksonville, FL

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