Jacksonville, FL to St. Louis, MO bus

Tue, Nov 18
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Journey information

Overview: Bus from Jacksonville, FL to St. Louis, MO

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Take a bus from Jacksonville, FL to St. Louis, MO and enjoy the approximately 751 miles (1209 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 01:45, the last at 23:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
751 miles (1209 km)
Buses per day
3
First bus
01:45
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Jacksonville, FL to St. Louis, MO

Find answers to the most common questions about traveling from Jacksonville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Jacksonville, FL to St. Louis, MO can start from as little as $264 (€214) when you book in advance. The average bus ticket price for Jacksonville, FL to St. Louis, MO is $264 (€214); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from Jacksonville, FL to St. Louis, MO is on average 21 h 5 min   for the 749 mile (1208 km) long journey, but the time it takes to go between Jacksonville, FL and St. Louis, MO by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Jacksonville, FL to St. Louis, MO leaves at 1: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Jacksonville, FL to St. Louis, MO leaves at 9: 40PM.
The cheapest month for a bus from Jacksonville, FL to St. Louis, MO is December.
Yes, you can take a bus to St. Louis, MO from Jacksonville, FL.
No, the bus from Jacksonville, FL to St. Louis, MO has no accessibility options.
No, there are no bathrooms on board the bus from Jacksonville, FL to St. Louis, MO.
No, bikes are not allowed on board the bus from Jacksonville, FL to St. Louis, MO.

To find the cheapest bus tickets for your trip from Jacksonville, FL to St. Louis, MO, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Jacksonville, FL to St. Louis, MO.
    No, luggage for the bus from Jacksonville, FL to St. Louis, MO needs to be booked in addition.
    No, there are no additional luggage options for the bus from Jacksonville, FL to St. Louis, MO.
    Unfortunately, pets are not allowed on the bus from Jacksonville, FL to St. Louis, MO.
    No, there are no USB plugs on board the bus from Jacksonville, FL to St. Louis, MO.
    No, there is no WiFi on board the bus from Jacksonville, FL to St. Louis, MO.

    popular bus stations

    Popular bus stations from Jacksonville, FL to St. Louis, MO

    Jacksonville
    St. Louis
    The major bus station for departures in Jacksonville is Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. Find all the information you need to know about services, amenities and connections at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St for your trip from Jacksonville to St. Louis.
    Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
    information

    More options for your journey from Jacksonville, FL to St. Louis, MO

    Here are some other resources that might have the information you need

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    Tickets and more information for coaches to St. Louis, MO

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