- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Jacksonville, FL to St. Louis, MO
Showing times, prices and bookable tickets for Oct 09
Cheapest price on Oct 09
$115
Average ticket price on Oct 09
$116
Fastest journey on Oct 09
17 h 50 m
Average journey duration on Oct 09
18 h 40 m
Buses on Oct 09
2
Distance
1209 km
Cheap tickets
The best way to find a cheap bus ticket from Jacksonville, FL to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to St. Louis, MO will cost around $116 if you buy it on the day, but the cheapest tickets can be found for only $115.
Fast buses
It's difficult to get from Jacksonville, FL to St. Louis, MO without transferring at least once.
FlixBus+
· 9:25 PM19h30Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St3:55 PMSt. Louis, S 15th St (Civic center)$1151One-way2 transfers- FlixBus · FlixBus4:30 PM17h50Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:20 AMSt. Louis, S 15th St (Civic center)$1171One-way1 transfer
- FlixBus · FlixBus4:30 PM17h50Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:20 AMSt. Louis, S 15th St (Civic center)$1171One-way1 transfer
- FlixBus+ · 9:25 PM19h30Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St3:55 PMSt. Louis, S 15th St (Civic center)$1151One-way2 transfers
Journey information
Overview: Bus from Jacksonville, FL to St. Louis, MO
USAUSA
Buses from Jacksonville, FL to St. Louis, MO run on average 2 times per day, taking around 18h 9m. Cheap bus tickets for this journey start at $91 (€76) if you book in advance.
The earliest bus runs at 01:55, the last at 23:45. The fastest bus covers the 751 miles (1209 km) distance in 16h 41m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 751 miles (1209 km) |
Average bus duration 18h 9m |
Cheapest ticket price $91 (€76) |
Buses per day 2 |
Fastest bus 16h 41m |
First bus 1:55 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Jacksonville, FL to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 03:10PM | Duration 30h10 | Departure days Tue | Cheapest price $95 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 02:15PM | Duration 22h45 | Departure days Mon | Cheapest price $107 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 09:20AM | Duration 17h50 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 03:55PM | Duration 19h30 | Departure days Everyday | Cheapest price $95 |
Operator Greyhound | Departure Time 11:15PM | Arrival Time 09:20AM | Duration 35h05 | Departure days Tue | Cheapest price $108 |
Live departures
Jacksonville, FL to St. Louis, MO bus times
The table below shows live departures for Jacksonville, FL to St. Louis, MO buses for today, Thursday, October 8. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 4:30 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 17h50 | 9:20 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| FlixBus+ · | 9:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 19h30 | 3:55 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Jacksonville, FL to St. Louis, MO buses with Omio?
Greyhound as well as FlixBus offer buses services from Jacksonville, FL to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Jacksonville, FL to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Jacksonville, FL to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Jacksonville, FL to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Jacksonville, FL to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Jacksonville, FL to St. Louis, MO.
Bus providers: Greyhound, FlixBus from Jacksonville, FL to St. Louis, MOYou can travel by bus between Jacksonville, FL to St. Louis, MO with Greyhound, FlixBus for as low as $91 (€76). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 41m
Cheapest FlixBus Price
$94 (€79)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
18h 10m
Cheapest Greyhound Price
$91 (€76)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Jacksonville, FL to St. Louis, MO
Find answers to the most common questions about traveling from Jacksonville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Jacksonville, FL to St. Louis, MO can start from as little as $91 (€76) when you book in advance. The average bus ticket price for Jacksonville, FL to St. Louis, MO is $146 (€123) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Jacksonville, FL to St. Louis, MO is 16h 41m to travel the 751 miles (1209 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Jacksonville, FL to St. Louis, MO leaves at 1:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jacksonville, FL to St. Louis, MO leaves at 11:45 PM.
There are 2 buses a day from Jacksonville, FL to St. Louis, MO which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Jacksonville, FL to St. Louis, MO, you can count on Greyhound, FlixBus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Jacksonville, FL and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Jacksonville, FL and St. Louis, MO including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Jacksonville, FL to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Jacksonville, FL to St. Louis, MO for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Jacksonville, FL to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Jacksonville, FL to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Jacksonville, FL to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Jacksonville, FL to St. Louis, MO:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Jacksonville, FL to St. Louis, MO. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Jacksonville, FL to St. Louis, MO with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Jacksonville, FL to St. Louis, MO with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Jacksonville, FL to St. Louis, MO with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Jacksonville, FL to St. Louis, MO
Most Jacksonville, FL to St. Louis, MO buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Jacksonville, FL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Jacksonville
Arrival bus stations in St. Louis
Which Jacksonville, FL station do buses to St. Louis, MO leave from?
Buses from Jacksonville, FL to St. Louis, MO leave from Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. The station is 1 miles (2 km) from Jacksonville, FL city centre at 1111 W Forsyth St, Jacksonville, FL 32204, USA.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St1111 W Forsyth St, Jacksonville, FL 32204, USA
City-centre transport
Getting to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St from Jacksonville city centre
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Bus1, 11, 18, 205, 3, Nassau, St. Johns, Clay · 12m · $4 · every ~18 min
1, 19, 3 · 17m · $4 · every ~17 min
SubwaySky · 10m · every ~4 min
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St bus station facilities and services
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Tickets and information
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Parking, taxis and toilets
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
Which St. Louis, MO station do buses from Jacksonville, FL arrive at?
Buses from Jacksonville, FL to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Most popular bus connections from Jacksonville, FL
More options for your journey from Jacksonville, FL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Jacksonville, FL
Most popular bus connections to St. Louis, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
